gamma-butyrolactone
4-hydroxybutyric acid lactone
Identification
| Name | gamma-butyrolactone |
| IUPAC | oxolan-2-one |
| CAS Number | 96-48-0 |
| EINECS | 202-509-5 |
| FDA UNII | OL659KIY4X |
| Molecular Formula | C4 H6 O2 |
| Molecular Weight | 86.09022000 |
| MDL Number | MFCD00005386 |
| Nikkaji Number | J3.971C |
| Beilstein | 0105248 |
| CoE Number | 615 |
| XlogP3 | -0.60 (est) |
Regulatory
| JECFA Food Flavoring | 219 4-hydroxybutyric acid lactone |
| DG SANTE Food Flavourings | 10.006 butyro-1,4-lactone |
| FEMA Number | 3291 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 96-48-0 ; 4-HYDROXYBUTANOIC ACID LACTONE |
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | Yes |
| Specific Gravity | 1.12000 to 1.13000 @ 25.00 °C. |
| Pounds per Gallon - (est). | 9.320 to 9.403 |
| Refractive Index | 1.43000 to 1.44000 @ 20.00 °C. |
| Melting Point | -43.30 °C. @ 760.00 mm Hg |
| Boiling Point | 204.00 to 205.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.450000 mmHg @ 25.00 °C. |
| Vapor Density | 3.00 ( Air = 1 ) |
| Flash Point | 209.00 °F. TCC ( 98.33 °C. ) |
| logP (o/w) | -0.640 |
| Soluble in | alcohol |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | fragrance |
Organoleptic Properties
| Odor Description |
at 100.00 %. Creamy, oily with fatty nuances SWEET, AROMATIC, CREAMY OILY, CREAMY, FATTY Caramel, Fatty, Creamy SWEET, AROMATIC, CREAMY
|
| Taste Description | at 75.00 ppm. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 1540 mg/kg |
| Dermal Toxicity | skin-guinea pig LD50 > 5000 mg/kg |
| Inhalation Toxicity | inhalation-rat LC50 > 5100 mg/m3/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION\nBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for gamma-butyrolactone usage levels up to | 0.5000 % in the fragrance concentrate. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 110.00 (μg/capita/day) |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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