2-hydroxybenzaldehyde

o-hydroxybenzaldehyde

CAS: 90-02-8 C7 H6 O2 MW: 122.12322000 medicinal spicy

Identification

Name2-hydroxybenzaldehyde
IUPAC2-hydroxybenzaldehyde
CAS Number90-02-8
EINECS201-961-0
FDA UNII17K64GZH20
Molecular FormulaC7 H6 O2
Molecular Weight122.12322000
MDL NumberMFCD00003317
Nikkaji NumberJ10.607K
Beilstein0471388
CoE Number605
XlogP31.80 (est)

Regulatory

JECFA Food Flavoring897 salicylaldehyde
DG SANTE Food Flavourings05.055 salicylaldehyde
FEMA Number3004
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)90-02-8 ; SALICYLALDEHYDE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to pale yellow clear oily liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.16300 to 1.16800 @ 20.00 °C.
Pounds per Gallon - (est). 9.689 to 9.730
Refractive Index 1.57100 to 1.57400 @ 20.00 °C.
Melting Point 1.00 to 2.00 °C. @ 760.00 mm Hg
Boiling Point 196.00 to 197.00 °C. @ 760.00 mm Hg, 96.00 to 97.00 °C. @ 30.00 mm Hg
Acid Value 10.00 max. KOH/g
Vapor Pressure 0.329000 mmHg @ 25.00 °C. (est)
Vapor Density 4.2 ( Air = 1 )
Flash Point 170.00 °F. TCC ( 76.67 °C. )
logP (o/w) 1.810
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Description
at 10.00 % in dipropylene glycol.
Medicinal, spicy cinnamon-wintergreen like cooling note
Taste Description at 20.00 ppm.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience2 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 520 mg/kg
Dermal Toxicityskin-rabbit LD50 3000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for 2-hydroxybenzaldehyde usage levels up to1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)84.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)16.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum11.00000
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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R C Treatt and Co Ltd

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Potential Uses

FR cassia FR cinnamon FR coffee FR grape FR meadowsweet FR seaweed absolute replacer FR spice spirea FL tea FR tobacco FL tomato FR vanilla FR violet FR wallflower

Natural Occurrence

buckwheat seed cassia castoreum PMC cinnamomum fragrans baillon leaf oil madagascar @ 0.20% Data cinnamon oil CO2 extract @ 0.04-0.23% Data grape muscat grape PMC peppermint leaf sherry PMC tea leaf tomato fruit vanilla

Synonyms

benzaldehyde, 2-hydroxy- 2- formyl phenol ortho- formyl phenol 2- formylphenol o- formylphenol ortho- formylphenol 2- hydroxybenzaldehyde o- hydroxybenzaldehyde ortho- hydroxybenzaldehyde salicyl aldehyde salicylal salicylaldehyde salicylic aldehyde PubMed: Novel salicylaldehyde derivatives as fluorescence turn-on sensors for cyanide ion. PubMed: Determination and depletion of amoxicillin residues in eggs. PubMed: Potent nematicidal activity of phthalaldehyde, salicylaldehyde, and cinnamic aldehyde against Meloidogyne incognita. PubMed: Identification and quantification of aroma compounds of tartary buckwheat (Fagopyrum tataricum Gaertn.) and some of its milling fractions. PubMed: [Antibacterial activity of essential oil vapor for histamine-producing bacteria]. PubMed: Influence of irradiation time and solution concentration on the photochemical degradation of EDDHA/Fe3+: effect of its photodecomposition products on soybean growth. PubMed: The determination of some heavy metals in food samples by flame atomic absorption spectrometry after their separation-preconcentration on bis salicyl aldehyde, 1,3 propan diimine (BSPDI) loaded on activated carbon. PubMed: Sequestration of plant-derived phenolglucosides by larvae of the leaf beetle Chrysomela lapponica: thioglucosides as mechanistic probes. PubMed: Food protective and color alteration effects of acaricidal aldehydes on Tyrophagus putrescentiae (Schrank). PubMed: Isolation of antioxidant compounds from the methanolic extract of the roots of Decalepis hamiltonii (Wight and Arn.). PubMed: L-tryptophan reacts with naturally occurring and food-occurring phenolic aldehydes to give phenolic tetrahydro-beta-carboline alkaloids: activity as antioxidants and free radical scavengers. PubMed: Characterization of an extracellular salicyl alcohol oxidase from larval defensive secretions of Chrysomela populi and Phratora vitellinae (Chrysomelina). PubMed: Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. PubMed: Determination of daminozide residues in apple pulp using HPLC-DAD-UV. PubMed: Growth-Inhibiting Effects of Cinnamomum cassia Bark-Derived Materials on Human Intestinal Bacteria. PubMed: Insecticidal and fumigant activities of Cinnamomum cassia bark-derived materials against Mechoris ursulus (Coleoptera: attelabidae). PubMed: Modified gas chromatographic/mass spectrometric method for determination of daminozide in high protein food products. PubMed: Toxins in chrysomelid beetles Possible evolutionary sequence from de novo synthesis to derivation from food-plant chemicals. PubMed: Hyperthermic and anorectic effects of oxazolidines derived from L-ephedrine in rats.