symphytum officinale root extract

extract of the roots of the comfrey, symphytum officinale l., boraginaceae

CAS: 84696-05-9

Identification

Namesymphytum officinale root extract
IUPACsymphytum officinale root extract
CAS Number84696-05-9
FDA UNIISearch

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantidandruff agents

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantidandruff agents
Recommendation for symphytum officinale root extract usage levels up tonot for fragrance use.
Recommendation for symphytum officinale root extract flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

comfrey

Synonyms

comfrey root extract quaker comfrey root extract extract of the roots of the comfrey, symphytum officinale l., boraginaceae symphytum officinalis root extract PubMed: Comparative Study of the Biological Activity of Allantoin and Aqueous Extract of the Comfrey Root. PubMed: Herbal medicine for low-back pain. PubMed: TLC densitometric method for screening of lycopsamine in comfrey root (Symphytum officinale L.) extracts using retrorsine as a reference compound. PubMed: Semi-automated separation of the epimeric dehydropyrrolizidine alkaloids lycopsamine and intermedine: preparation of their N-oxides and NMR comparison with diastereoisomeric rinderine and echinatine. PubMed: Comfrey root: from tradition to modern clinical trials. PubMed: Distinct cell-specific expression of homospermidine synthase involved in pyrrolizidine alkaloid biosynthesis in three species of the boraginales. PubMed: Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. PubMed: MicroRNAs and their predicted target messenger RNAs are deregulated by exposure to a carcinogenic dose of comfrey in rat liver. PubMed: Absence of mutagenic effects of a particular Symphytum officinale L. liquid extract in the bacterial reverse mutation assay. PubMed: Lead chelation to immobilised Symphytum officinale L. (comfrey) root tannins. PubMed: Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver. PubMed: Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts. PubMed: Efficacy and tolerance of a comfrey root extract (Extr. Rad. Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study. PubMed: A rapid cleanup method for the isolation and concentration of pyrrolizidine alkaloids in comfrey root. PubMed: The influence of phytohormones on growth, organ differentiation and fructan production in callus of Symphytum officinale L. PubMed: Mutagenic effects of aqueous extracts of Symphytum officinale L. and of its alkaloidal fractions. PubMed: [Development of root-layers of symphytum officinale L. and their storage and consumption of carbohydrates]. PubMed: [Annual developmental cycle of roots and shoots in Symphytum officinale L. in relation to storage and consumption of carbohydrates]. PubMed: Comfrey (Symphytum officinale L.) root; its anatomy and its detection in admixture with chicory in dandelion coffee.