glycyrrhiza glabra rhizome/root extract

extract of the roots and rhizomes of the licorice, glycyrrhiza glabra l., fabaceae

CAS: 84775-66-6 licorice licorice

Identification

Nameglycyrrhiza glabra rhizome/root extract
IUPACglycyrrhiza glabra rhizome/root extract
CAS Number84775-66-6
FDA UNIISearch

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices184.1408
FEMA Number2628
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)68916-91-6 ; LICORICE EXTRACT (GLYCYRRHIZA SPP.)
FDA RegulationFDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

Organoleptic Properties

Odor Description at 100.00 %.
Taste Description licorice

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Horner International

The finest extracts in the world

Horner International supplies the finest natural extracts and flavors to a world-wide customer base.

View All Website +1 919 787 3112 ext. 112 lisa.ramraj@hornerintl.com

Potential Uses

None Found

Natural Occurrence

licorice PbMd

Synonyms

extract of the roots and rhizomes of the licorice, glycyrrhiza glabra l., fabaceae licorice rhizome/root extract PubMed: Aqueous extracts and polysaccharides from liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. PubMed: Comparative Analysis of Antibacterial Properties and Chemical Composition of Glycyrrhiza glabra L. from Astrakhan Region (Russia) and Calabria Region (Italy). PubMed: Evaluation of sodium benzoate and licorice (Glycyrrhiza glabra) root extract as heat-sensitizing additives against Escherichia coli O157:H7 in mildly heated young coconut liquid endosperm. PubMed: Enhancement of Hippocampal CA3 Neuronal Dendritic Arborization by Glycyrrhiza glabra root extract Treatment in Wistar Albino Rats. PubMed: Qualitative identification of dibenzoylmethane in licorice root (Glycyrrhiza glabra) using gas chromatography-triple quadrupole mass spectrometry. PubMed: A Simple Semi-preparative Reversed-phase HPLC/PDA Method for Separation and Quantification of Glycyrrhizin in Nine Samples of Glycyrrhiza glabra Root Collected from Different Geographical Origins. PubMed: Liquorice, a unique "guide drug" of traditional Chinese medicine: a review of its role in drug interactions. PubMed: Absolute configuration of naturally occurring glabridin. PubMed: Beneficial effect of aqueous root extract of Glycyrrhiza glabra on learning and memory using different behavioral models: An experimental study. PubMed: Transdermal microemulsions of Glycyrrhiza glabra L.: characterization, stability and evaluation of antioxidant potential. PubMed: Improving the thrombin inhibitory activity of glycyrrhizin, a triterpenic saponin, through a molecular simplification of the carbohydrate moiety. PubMed: Glycyrrhizin ameliorates insulin resistance, hyperglycemia, dyslipidemia and oxidative stress in fructose-induced metabolic syndrome-X in rat model. PubMed: Comparison of three officinal Chinese pharmacopoeia species of Glycyrrhiza based on separation and quantification of triterpene saponins and chemometrics analysis. PubMed: Effect of GutGard in the Management of Helicobacter pylori: A Randomized Double Blind Placebo Controlled Study. PubMed: Application of Glycyrrhiza glabra root as a novel adsorbent in the removal of toluene vapors: equilibrium, kinetic, and thermodynamic study. PubMed: Anti-convulsant action and amelioration of oxidative stress by Glycyrrhiza glabra root extract in pentylenetetrazole- induced seizure in albino rats. PubMed: [Genetic effects of root extracts of Glycyrrhiza glabra L. on different test-systems]. PubMed: In vitro studies on protective effect of Glycyrrhiza glabra root extracts against cadmium-induced genetic and oxidative damage in human lymphocytes. PubMed: Treatment of licorice seeds with colchicine: changes in seedling DNA levels and anthocyanin and glycyrrhizic acid contents of derived callus cultures. PubMed: Chromolithic method development, validation and system suitability analysis of ultra-sound assisted extraction of glycyrrhizic acid and glycyrrhetinic acid from Glycyrrhiza glabra. PubMed: High throughput screening to identify natural human monoamine oxidase B inhibitors. PubMed: An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts. PubMed: Licorice induced hypokalemia, edema, and thrombocytopenia. PubMed: Licochalcone a inhibits lipopolysaccharide-induced inflammatory response in vitro and in vivo. PubMed: ISSR and RAPD based evaluation of genetic stability of encapsulated micro shoots of Glycyrrhiza glabra following 6 months of storage. PubMed: Glycyrrhizin and long-term histopathologic changes in a murine model of asthma. PubMed: Biogeography of symbiotic and other endophytic bacteria isolated from medicinal Glycyrrhiza species in China. PubMed: Evaluation of the genotoxic potential of standardized extract of Glycyrrhiza glabra (GutGard™). PubMed: Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra). PubMed: Modulation of lipopolysaccharide-induced pro-inflammatory mediators by an extract of Glycyrrhiza glabra and its phytoconstituents. PubMed: Ameliorative effects of glycyrrhizin on streptozotocin-induced diabetes in rats. PubMed: Evaluation of the Anticonvulsant Activity of the Leaves of Glycyrrhiza glabra var. glandulifera Grown in Iran, as a Possible Renewable Source for Anticonvulsant Compounds. PubMed: Black licorice ingestion: Yet another confounding agent in patients with melena. PubMed: Metabolic profiling of roots of liquorice (Glycyrrhiza glabra) from different geographical areas by ESI/MS/MS and determination of major metabolites by LC-ESI/MS and LC-ESI/MS/MS. PubMed: Leaves Antimicrobial Activity of Glycyrrhiza glabra L. PubMed: Dual inhibitory effect of Glycyrrhiza glabra (GutGard™) on COX and LOX products. PubMed: 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice. PubMed: The effect of licorice drink on the systemic exposure of verapamil in rabbits. PubMed: The Effect of Licorice Drink on the Systemic Exposure of Verapamil in Rabbits. PubMed: Natural anti-inflammatory products and leukotriene inhibitors as complementary therapy for bronchial asthma. PubMed: Antidyslipidaemic activity of Glycyrrhiza glabra in high fructose diet induced dsyslipidaemic Syrian golden hamsters. PubMed: Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway. PubMed: A rapid screening method for prenylated flavonoids with ultra-high-performance liquid chromatography/electrospray ionisation mass spectrometry in licorice root extracts. PubMed: Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine. PubMed: Evaluation of antioxidant and anti-atherogenic properties of Glycyrrhiza glabra root using in vitro models. PubMed: [Cloning and characterization of cDNA encoding Psammosilene tunicoides squalene synthase]. PubMed: Isoliquiritigenin, a flavonoid from licorice, plays a dual role in regulating gastrointestinal motility in vitro and in vivo. PubMed: In vitro effects of glycyrrhetinic acid on the growth of clinical isolates of Candida albicans. PubMed: Anti-proliferative effect of licochalcone A on vascular smooth muscle cells. PubMed: Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice. PubMed: Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice. PubMed: Isoliquiritigenin, a flavonoid from licorice, relaxes guinea-pig tracheal smooth muscle in vitro and in vivo: role of cGMP/PKG pathway. PubMed: Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root. PubMed: Role of P-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra. PubMed: Chemoprofile and bioactivities of Taverniera cuneifolia (Roth) Arn.: a wild relative and possible substitute of Glycyrrhiza glabra L. PubMed: Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra. PubMed: Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats. PubMed: Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats. PubMed: Simultaneous HPLC analysis, with isocratic elution, of glycyrrhizin and glycyrrhetic acid in liquorice roots and confectionery products. PubMed: Chemopreventive properties of the ethanol extract of chinese licorice (Glycyrrhiza uralensis) root: induction of apoptosis and G1 cell cycle arrest in MCF-7 human breast cancer cells. PubMed: Effect of licorice root on peripheral blood indexes upon vibration exposure. PubMed: Separation and analysis of glycyrrhizin, 18beta-glycyrrhetic acid and 18alpha-glycyrrhetic acid in liquorice roots by means of capillary zone electrophoresis. PubMed: Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts. PubMed: Licorice flavonoids suppress abdominal fat accumulation and increase in blood glucose level in obese diabetic KK-A(y) mice. PubMed: [Effects of nutrient solution concentration on inorganic and glycyrrhizin contents of Glycyrrhiza glabra Linn]. PubMed: Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. PubMed: Differential expression of three oxidosqualene cyclase mRNAs in Glycyrrhiza glabra. PubMed: Isoliquiritigenin inhibits the growth of prostate cancer. PubMed: Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine. PubMed: Antioxidant effect of licorice root on blood catalase activity in vibration stress. PubMed: Protection of DNA and microsomal membranes in vitro by Glycyrrhiza glabra L. against gamma irradiation. PubMed: Immunological studies of Revitonil, a phytopharmaceutical containing Echinacea purpurea and Glycyrrhiza glabra root extract. PubMed: [Comparative study of Glycyrrhiza glabra L. and Glycyrrhiza echinata L. of different origin. Medicinal plant polysaccharides III]. PubMed: Flavonoid constituents from Glycyrrhiza glabra hairy root cultures. PubMed: Antioxidant activity of parapharmaceutics containing natural inhibitors of free radical processes. PubMed: Biosynthesis of the dimethylallyl moiety of glabrol in Glycyrrhiza glabra hairy root cultures via a non-mevalonate pathway. PubMed: Antimicrobial flavonoids from Glycyrrhiza glabra hairy root cultures. PubMed: Activation of macrophages by crude polysaccharide fractions obtained from shoots of Glycyrrhiza glabra and hairy roots of Glycyrrhiza uralensis in vitro. PubMed: [Polysaccharides of Glycyrrhiza glabra L. and Glycyrrhiza echinata L. Medicinal plants II]. PubMed: Seasonal variation of glycyrrhizin and isoliquiritigenin glycosides in the root of Glycyrrhiza glabra L. PubMed: Structural aspects of the inhibitory effect of glabridin on LDL oxidation. PubMed: The antioxidative effects of the isoflavan glabridin on endogenous constituents of LDL during its oxidation. PubMed: Antioxidant constituents from licorice roots: isolation, structure elucidation and antioxidative capacity toward LDL oxidation. PubMed: Inhibition of human complement by beta-glycyrrhetinic acid. PubMed: Distribution Pattern of Saponins in Different Organs of Glycyrrhiza glabra. PubMed: A further contribution to the triterpenoid constituents of Glycyrrhiza glabra L. PubMed: Triterpenoid biosynthesis in tissue cultures of Glycyrrhiza glabra var. glandulifera. PubMed: Biotransformation of 18 beta-glycyrrhetinic acid by cell suspension cultures of Glycyrrhiza glabra. PubMed: Examination of triterpenoids produced by callus and cell suspension cultures of Glycyrrhiza glabra. PubMed: [Identification of some flavonic aglycones in root extracts of Glycyrrhiza glabra L]. PubMed: Isolation of two new flavonoids from the root of Glycyrrhiza glabra var. typica. PubMed: [Differences between the root and rhizome of Ural licorice (Glycyrrhiza uralensis Fisch.) and those of smooth licorice (Glycyrrhiza glabra L.)]. PubMed: [Liquiritoside, flavonoside from root of licorice, Glycyrrhiza glabra L]. PubMed: Evaluation of the genotoxic potential of standardized extract of Glycyrrhiza glabra (GutGard™). PubMed: Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6. PubMed: Memory enhancing activity of Glycyrrhiza glabra in mice.