Identification

Namemethyl 2-furoate
IUPACmethyl furan-2-carboxylate
CAS Number611-13-2
EINECS210-254-6
FDA UNIIO9A8D29YDE
Molecular FormulaC6 H6 O3
Molecular Weight126.11142000
MDL NumberMFCD00003236
Nikkaji NumberJ7.016E
Beilstein0111110
CoE Number358
XlogP31.00 (est)

Regulatory

JECFA Food Flavoring746 methyl 2-furoate
DG SANTE Food Flavourings13.002 methyl 2-furoate
FEMA Number2703
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)611-13-2 ; METHYL 2-FUROATE

Physical Properties

Appearance pale yellow to orange clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.17000 to 1.18000 @ 25.00 °C.
Pounds per Gallon - (est). 9.736 to 9.819
Refractive Index 1.48000 to 1.49000 @ 20.00 °C.
Boiling Point 181.00 to 182.00 °C. @ 760.00 mm Hg, 81.00 to 82.00 °C. @ 20.00 mm Hg
Vapor Pressure 0.858000 mmHg @ 25.00 °C. (est)
Vapor Density 3.7 ( Air = 1 )
Flash Point 164.00 °F. TCC ( 73.33 °C. )
logP (o/w) 1.000
Soluble in alcohol
Insoluble in water
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium ,
Substantivity 64 hour(s) at 100.00 %
Odor Description
at 10.00 % in dipropylene glycol.
A nutty, peppermint, tobacco odor with mushroom undertones
Fruity mushroom fungus tobacco sweet
Odor sample from Bedoukian Research, Inc.
Taste Description
sweet caramel brown sugar musty
Sweet, caramel, brown sugar, slightly musty
sweet caramel brown sugar musty

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience10 % solution: no irritation or sensitization.
Oral/Parenteral Toxicitygavage-rat LD50 [sex: M,F] 300 mg/kg
Dermal Toxicityskin-rabbit LD50 > 1250 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for methyl 2-furoate usage levels up to2.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)30.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)37.00 (μg/capita/day)
Threshold of Concern540 (μg/person/day)
Structure ClassII
baked goods1.00000
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy0.06000
fruit ices0.06000
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FR almond FL brandy FL chocolate cocoa FR coffee FR filbert FR fungus FL nut FR peanut FR peppermint FR tobacco FL tomato

Natural Occurrence

almond seed blackberry fruit PMC brandy PMC cocoa coffee PMC cognac PMC cranberry fruit filbert roasted filbert guava fruit honey PMC katsuobushi PMC kiwi fruit okra papaya fruit passion fruit juice peanut roasted peanut plum fruit potato baked potato raisin PMC rice soursop tamarind fruit oil tamarind seed oil tomato

Synonyms

2- furan carboxylic acid methyl ester furan-2-carboxylic acid methyl ester 2- furancarboxylic acid methyl ester 2- furancarboxylic acid, methyl ester furoic acid methyl ester 2- furoic acid methyl ester furoic acid, methyl ester 2- furoic acid, methyl ester 2-( methoxycarbonyl) furan 2-( methoxycarbonyl)furan methyl 2-furan carboxylate methyl 2-furancarboxylate methyl 2-furyl carboxylate methyl 2-furylcarboxylate methyl furan-2-carboxylate methyl pyromucate methyl-2-furoate pyromucic acid methyl ester PubMed: A tunable process: catalytic transformation of renewable furfural with aliphatic alcohols in the presence of molecular oxygen. PubMed: Aerobic oxidation of hydroxymethylfurfural and furfural by using heterogeneous Cox Oy -N@C catalysts. PubMed: Synthesis of terephthalic acid via Diels-Alder reactions with ethylene and oxidized variants of 5-hydroxymethylfurfural. PubMed: Enantioselective synthesis of xanthatin. PubMed: Cobalt-catalyzed C-H borylation. PubMed: Insertional mutagenesis and cloning of the gene required for the biosynthesis of the non-host-specific toxin in Cochliobolus lunatus that causes maize leaf spot. PubMed: Asymmetric synthesis of both enantiomers of arteludovicinolide A. PubMed: An efficient method for the determination of furan derivatives in apple cider and wine by solid phase extraction and high performance liquid chromatography--diode array detector. PubMed: Anti-fish nodaviral activity of furan-2-yl acetate extracted from marine Streptomyces spp. PubMed: [Secondary metabolites of a marine actinomycete Streptomyces sp. (No. 195-02) from South China Sea]. PubMed: Suppression of blood lipid concentrations by volatile Maillard reaction products. PubMed: 5-Furan-2yl[1,3,4]oxadiazole-2-thiol, 5-furan-2yl-4H [1,2,4] triazole-3-thiol and their thiol-thione tautomerism. PubMed: Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure. PubMed: [Bisbenzofuro[3,2-b: 2',3'-e]pyridines]. PubMed: A ceramic electrochemical microreactor for the methoxylation of methyl-2-furoate with direct mass spectrometry coupling. PubMed: Gas chromatography/mass spectrometric characterisation of pyrolysis/silylation products of glucose and cellulose. PubMed: Synthesis of enantiopure dihydropyranones: aldol-based ring expansion of dihydrofurans. PubMed: Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide. PubMed: Generation of Maillard compounds from inulin during the thermal processing of Agave tequilana Weber Var. azul. PubMed: Poikilothermia induced by a 2-furancarboxylic acid derivative. PubMed: High-performance liquid chromatographic determination of methyl anthranilate, hydroxymethylfurfural and related compounds in honey. PubMed: Analysis of the transformation products of dehydro-L-ascorbic acid by ion-pairing high-performance liquid chromatography. PubMed: Characterization of the interaction between human alpha-thrombin and methyl 3-(2-methyl-1-oxopropoxy)[1]benzothieno[3,2-b]furan-2-carboxylate (LY806303) using electrospray mass spectrometry and tandem mass spectrometry. PubMed: Mutagenicity of 3,4-diphenyl-5-nitrofuran analogs in Salmonella typhimurium. PubMed: Synthesis and evaluation of the antitumor properties of esters of 2-furoic acid and 2-furylacrylic acid.