silybum marianum fruit extract

extract of the fruit of the lady's thistle, silybum marianum (l.), asteraceae

CAS: 84604-20-6

Identification

Namesilybum marianum fruit extract
CAS Number84604-20-6
FDA UNIISearch

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LD50 681 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for silybum marianum fruit extract usage levels up tonot for fragrance use.
Recommendation for silybum marianum fruit extract flavor usage levels up tonot for flavor use.

ECSA Chemicals

Human Chemistry

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Potential Uses

None Found

Natural Occurrence

milk thistle

Synonyms

extract of the fruit of the lady's thistle, silybum marianum (l.), asteraceae lady's thistle fruit extract ladys thistle fruit extract milk thistle fruit extract st. mary's thistle fruit extract st. marys thistle fruit extract PubMed: Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum). PubMed: Absolute configuration of isosilybin A by X-ray crystallography of the heavy atom analogue 7-(4-Bromobenzoyl)isosilybin A. PubMed: Metabolic effects of silibinin in the rat liver. PubMed: Identification of novel pregnane X receptor activators from traditional Chinese medicines. PubMed: Methyl jasmonate increases silymarin production in Silybum marianum (L.) Gaernt cell cultures treated with β-cyclodextrins. PubMed: Milk thistle in liver diseases: past, present, future. PubMed: Silymarin BIO-C, an extract from Silybum marianum fruits, induces hyperprolactinemia in intact female rats. PubMed: Anti- and pro-mutagenic effects of silymarin in the Ames bacterial reverse mutation assay. PubMed: Pressurized water versus ethanol as a Silybum marianum extraction solvent for inhibition of low-density lipoprotein oxidation mediated by copper and J774 macrophage cells. PubMed: Immunosuppressive effect of silibinin in experimental autoimmune encephalomyelitis. PubMed: Silyamandin, a new flavonolignan isolated from milk thistle tinctures. PubMed: [Formation of flavanolignane in the white-flowered variety (Szibilla) of Silybum marianum in relation to fruit development]. PubMed: Use of Silybum marianum fruit extract in broiler chicken nutrition: influence on performance and meat quality. PubMed: [Study of inorganic elements in silybum marianum: distribution and extraction rate]. PubMed: Anticancer potential of silymarin: from bench to bed side. PubMed: Structure elucidation and antioxidant activity of (-)-isosilandrin isolated from Silybum marianum L. PubMed: Microbial transformation of silybin by Trichoderma koningii. PubMed: A silychristin isomer and variation of flavonolignan levels in milk thistle (Silybum marianum) fruits. PubMed: A review of the bioavailability and clinical efficacy of milk thistle phytosome: a silybin-phosphatidylcholine complex (Siliphos). PubMed: Silibinin down-regulates prostate epithelium-derived Ets transcription factor in LNCaP prostate cancer cells. PubMed: Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Part I. Silymarin and its flavonolignans. PubMed: Silibinin protects mice from T cell-dependent liver injury. PubMed: Physiological responses to a natural antioxidant flavonoid mixture, silymarin, in BALB/c mice: II. alterations in thymic differentiation correlate with changes in c-myc gene expression. PubMed: Determination of silymarine in the extract from the dried silybum marianum fruits by high performance liquid chromatography and capillary electrophoresis. PubMed: [Tissue and suspension cultures of Silybum marianum. I. Communication: isolation and growth of tissue and suspension cultures and studies on flavonoids (author's transl)]. PubMed: The effects of silymarin on experimental phalloidine poisoning. PubMed: [Separation of flavonoids from the fruits of St Mary's distel (Silybum marianum)].