methyl syringate
benzoic acid, 4-hydroxy-3,5-dimethoxy-, methyl ester
Identification
| Name | methyl syringate |
| IUPAC | methyl 4-hydroxy-3,5-dimethoxybenzoate |
| CAS Number | 884-35-5 |
| FDA UNII | W5A196MP8A |
| Molecular Formula | C10 H12 O5 |
| Molecular Weight | 212.20164000 |
| MDL Number | MFCD00017199 |
| Nikkaji Number | J356.639K |
| XlogP3 | 1.40 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 339.90 °C. @ 760.00 mm Hg (est) |
| Flash Point | 270.00 °F. TCC ( 132.40 °C. ) (est) |
| logP (o/w) | 1.100 (est) |
| Soluble in | water, 1485 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for methyl syringate usage levels up to | not for fragrance use. |
| Recommendation for methyl syringate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzoic acid, 4-hydroxy-3,5-dimethoxy-, methyl ester
methyl 4-hydroxy-3,5-dimethoxybenzoate
methyl syringoate
syringic acid methyl ester
syringic acid monomethyl ester
PubMed:
Immunochemical authentication of manuka honey using a monoclonal antibody specific to a glycoside of methyl syringate.
PubMed:
Plausible authentication of manuka honey and related products by measuring leptosperin with methyl syringate.
PubMed:
Differentiation of manuka honey from kanuka honey and from jelly bush honey using HS-SPME-GC/MS and UHPLC-PDA-MS/MS.
PubMed:
Pretreatment with laccase and a phenolic mediator degrades lignin and enhances saccharification of Eucalyptus feedstock.
PubMed:
Phytochemical and physical-chemical analysis of Polish willow (Salix spp.) honey: identification of the marker compounds.
PubMed:
The volatile profiles of a rare apple (Malus domestica Borkh.) honey: shikimic acid-pathway derivatives, terpenes, and others.
PubMed:
Cornflower (Centaurea cyanus L.) honey quality parameters: chromatographic fingerprints, chemical biomarkers, antioxidant capacity and others.
PubMed:
The TRPA1 agonist, methyl syringate suppresses food intake and gastric emptying.
PubMed:
Bioorganic diversity of rare Coriandrum sativum L. honey: unusual chromatographic profiles containing derivatives of linalool/oxygenated methoxybenzene.
PubMed:
Understanding pulp delignification by laccase-mediator systems through isolation and characterization of lignin-carbohydrate complexes.
PubMed:
Methyl syringate, a low-molecular-weight phenolic ester, as an activator of the chemosensory ion channel TRPA1.
PubMed:
Obtaining biobleached eucalyptus cellulose fibres by using various enzyme combinations.
PubMed:
Methyl syringate: an efficient phenolic mediator for bacterial and fungal laccases.
PubMed:
Riboflavin and lumichrome in Dalmatian sage honey and other unifloral honeys determined by LC-DAD technique.
PubMed:
Laccase for biobleaching of eucalypt kraft pulp by means of a modified industrial bleaching sequence.
PubMed:
Polyphenolic profile as a useful tool to identify the wood used in wine aging.
PubMed:
Classification and characterization of manuka honeys based on phenolic compounds and methylglyoxal.
PubMed:
Identification of a novel glycoside, leptosin, as a chemical marker of manuka honey.
PubMed:
Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds.
PubMed:
Towards industrially-feasible delignification and pitch removal by treating paper pulp with Myceliophthora thermophila laccase and a phenolic mediator.
PubMed:
Volatile compounds of Asphodelus microcarpus Salzm. et Viv. Honey obtained by HS-SPME and USE analyzed by GC/MS.
PubMed:
Phenolic compounds as enhancers in enzymatic and electrochemical oxidation of veratryl alcohol and lignins.
PubMed:
Triterpenoidal alkaloids from Buxus natalensis and their acetylcholinesterase inhibitory activity.
PubMed:
Composition of sulla (Hedysarum coronarium L.) honey solvent extractives determined by GC/MS: norisoprenoids and other volatile organic compounds.
PubMed:
Organic extractives from Mentha spp. honey and the bee-stomach: methyl syringate, vomifoliol, terpenediol I, hotrienol and other compounds.
PubMed:
Phenolic compounds in cherry ( Prunus avium ) heartwood with a view to their use in cooperage.
PubMed:
Biodegradability of kraft mill TCF biobleaching effluents: application of enzymatic laccase-mediator system.
PubMed:
Headspace, volatile and semi-volatile organic compounds diversity and radical scavenging activity of ultrasonic solvent extracts from Amorpha fruticosa honey samples.
PubMed:
Methyl syringate: a chemical marker of asphodel (Asphodelus microcarpus Salzm. et Viv.) monofloral honey.
PubMed:
Copper-induced peroxidation of phosphatidylserine-containing liposomes is inhibited by nanomolar concentrations of specific antioxidants.
PubMed:
Mediator-assisted laccase-catalyzed oxidation of 4-hydroxybiphenyl.
PubMed:
Laccase-catalysed iodide oxidation in presence of methyl syringate.
PubMed:
Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum.
PubMed:
Aromatic compound glucosides, alkyl glucoside and glucide from the fruit of anise.
PubMed:
Dioxygen reactivity of laccase: dependence on laccase source, pH, and anion inhibition.
PubMed:
Multichannel coulometric detection coupled with liquid chromatography for determination of phenolic esters in honey.
PubMed:
Synergistic action of phenolic signal compounds and carbohydrates in the induction of virulence gene expression of Agrobacterium tumefaciens.