thiiranepropane nitrile
4,5-epithiovaleronitrile
Identification
| Name | thiiranepropane nitrile |
| IUPAC | 3-(thiiran-2-yl)propanenitrile |
| CAS Number | 54096-45-6 |
| FDA UNII | Search |
| Molecular Formula | C5 H7 N S |
| Molecular Weight | 113.18279000 |
| Nikkaji Number | J96.714I |
| Beilstein | 1362236 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.352e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for thiiranepropane nitrile usage levels up to | not for fragrance use. |
| Recommendation for thiiranepropane nitrile flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
1-
cyano-3,4-epithiobutane
3-(
thiiran-2-yl)propanenitrile
thiiranepropanenitrile
3-(2-
thiiranyl)propanenitrile
4,5-epi
thiopentane nitrile
4,5-epi
thiopentanenitrile
4,5-epi
thiovaleronitrile
valeronitrile, 4,5-epithio-
PubMed:
Could nitrile derivatives of turnip (Brassica rapa) glucosinolates be hepato- or cholangiotoxic in cattle?
PubMed:
Kinetic changes in glucosinolate-derived volatiles by heat-treatment and myrosinase activity in nakajimana (Brassica rapa L. cv. nakajimana).
PubMed:
1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic alpha,beta-unsaturated aldehyde acrolein.
PubMed:
Identification of the 1-cyano-3,4-epithiobutane-derived urinary mercapturic acid N-acetyl-S-(4-cyano-2-thio-1-butyl)-cysteine in male Fischer 344 rats.
PubMed:
Protection from 1-cyano-3,4-epithiobutane nephrotoxicity by aminooxyacetic acid and effect on xenobiotic-metabolizing enzymes in male Fischer 344 rats.
PubMed:
The effect of glutathione depletion by buthionine sulphoximine on 1-cyano-3,4-epithiobutane toxicity.
PubMed:
Sequential changes in hepatic and renal glutathione and development of renal karyomegaly in 1-cyano-3,4-epithiobutane toxicity in rats.
PubMed:
Comparative toxicities of the naturally occurring nitrile 1-cyano-3,4-epithiobutane and the synthetic nitrile n-valeronitrile in rats: differences in target organs, metabolism and toxic mechanisms.
PubMed:
Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake.