cycloalliin
3-methyl-1,4-thiazane-5-carboxylic acid-1-oxide
Identification
| Name | cycloalliin |
| IUPAC | (5S)-5-methyl-1-oxo-1,4-thiazinane-2-carboxylic acid |
| CAS Number | 455-41-4 |
| FDA UNII | WP7066JG47 |
| Molecular Formula | C6 H11 N O3 S |
| Molecular Weight | 177.22327000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 462.55 °C. @ 760.00 mm Hg (est) |
| Flash Point | 452.00 °F. TCC ( 233.50 °C. ) (est) |
| logP (o/w) | -1.279 (est) |
| Soluble in | water, 2.716e+005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cycloalliin usage levels up to | not for fragrance use. |
| Recommendation for cycloalliin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
cycloallin
(5S)-5-
methyl-1-oxo-1,4-thiazinane-2-carboxylic acid
3-
methyl-1,4-thiazane-5-carboxylic acid-1-oxide
3-
thiomorpholinecarboxylic acid, 5-methyl-, 1-oxide, (1S-(1a,3b,5b))-
3-
thiomorpholinecarboxylic acid, 5-methyl-, 1-oxide, (1S-(1alpha,3beta,5beta))-
PubMed:
Pharmacokinetics of cycloalliin, an organosulfur compound found in garlic and onion, in rats.
PubMed:
Cycloalliin, a cyclic sulfur imino acid, reduces serum triacylglycerol in rats.
PubMed:
Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood.
PubMed:
[On the biosynthesis of cycloalliin].
PubMed:
Anti-obesity effects of onion extract in Zucker diabetic fatty rats.
PubMed:
Effect of genetic characteristics and environmental factors on organosulfur compounds in garlic ( Allium sativum L.) grown in Andalusia, Spain.
PubMed:
Changes in organosulfur compounds in garlic cloves during storage.
PubMed:
[Related substances in purified alliin determined by HPLC-MS/MS].
PubMed:
Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms.
PubMed:
Synthesis of a cycloallin derivative from beta-cyclodextrin: heptakis(2,3-dideoxy-2,3-epithio)-beta-cycloallin.
PubMed:
Antioxidant functions of selected allium thiosulfinates and S-alk(en)yl-L-cysteine sulfoxides.
PubMed:
Determination of seven organosulfur compounds in garlic by high-performance liquid chromatography.
PubMed:
On the health benefits of Allium sp.