2H,8H-benzo(1,2-b:3,4-b')dipyran-2-one, 8,8-dimethyl-

CAS: 523-59-1 C14 H12 O3 MW: 228.24724000

Identification

Nameseselin
IUPAC8,8-dimethylpyrano[2,3-f]chromen-2-one
CAS Number523-59-1
FDA UNII5634E8957P
Molecular FormulaC14 H12 O3
Molecular Weight228.24724000
MDL NumberMFCD01018179
Nikkaji NumberJ11.874E

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 60.34 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for seselin usage levels up tonot for fragrance use.
Recommendation for seselin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

anise leaf bowdichia virgilioides root carum roxburghianum celery seed fennel seed lemon leaf lemon root mandarin root orange root

Synonyms

2H,8H- benzo(1,2-b:3,4-b')dipyran-2-one, 8,8-dimethyl- 8,8- dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-2-one 8,8- dimethylpyrano[2,3-f]chromen-2-one PubMed: Isolation of seselin from Clausena anisata (Rutaceae) leaves and its effects on the feeding and development of Lucilia cuprina larvae may explain its use in ethnoveterinary medicine. PubMed: Antithrombotic activity of a newly synthesized coumarin derivative 3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-N-{2-[3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-propionylamino]-ethyl}-propionamide. PubMed: Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh. PubMed: Structure and in vitro antiparasitic activity of constituents of Citropsis articulata root bark. PubMed: 6-Butyryl-5-hy-droxy-4-phenyl-seselin. PubMed: Isolation of xanthyletin, an inhibitor of ants' symbiotic fungus, by high-speed counter-current chromatography. PubMed: Botanical origin of Indian celery seed (fruit). PubMed: [Synthesis and antinociceptive activity of seselin derivatives]. PubMed: Seselin from Plumbago zeylanica inhibits phytohemagglutinin (PHA)-stimulated cell proliferation in human peripheral blood mononuclear cells. PubMed: Antinociceptive activity of the pyranocoumarin seselin in mice. PubMed: Natural and synthetic 2,2-dimethylpyranocoumarins with antibacterial activity. PubMed: Synthesis and evaluation of the antioxidant and antiinflammatory activities of some benzo[l]khellactone derivatives and analogues. PubMed: Cytotoxic naphthoquinones and plumbagic acid glucosides from Plumbago zeylanica. PubMed: Antiproliferative effect of isopentenylated coumarins on several cancer cell lines. PubMed: Anti-inflammatory activity of coumarins from Decatropis bicolor on TPA ear mice model. PubMed: Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series. PubMed: Anti-AIDS agents. 15. Synthesis and anti-HIV activity of dihydroseselins and related analogs. PubMed: Biological activity of some coumarins from Sri Lankan Rutaceae. PubMed: Identification of eight coumarins occurring with psoralen, xanthotoxin, and bergapten on leaf surfaces. PubMed: Pharmacological activities of the prenylcoumarins, developed from folk usage as a medicine of Peucedanum japonicum THUNB. PubMed: Studies on the anti-tumor-promoting activity of naturally occurring substances. IV. Pd-II [(+)anomalin, (+)praeruptorin B], a seselin-type coumarin, inhibits the promotion of skin tumor formation by 12-O-tetradecanoylphorbol-13-acetate in 7,12-dimethylbenz[a]anthracene-initiated mice. PubMed: Plant antitumor agents, 21. Flavones, coumarins, and an alkaloid from Sargentia greggii. PubMed: Calcium antagonist-like actions of coumarins isolated from "Qian-Hu" on anaphylactic mediator release from mast cell induced by concanavalin A. PubMed: Effects of Seselin and Coumarin on Growth, Indoleacetic Acid Oxidase, and Peroxidase, with Special Reference to Cucumber (Cucumis sativa L.) Radicles. PubMed: [Therapeutic possibilities of a seselin in the treatment of some heart diseases].