byakangelicin

7H-furo(3,2-g)(1)benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-

CAS: 482-25-7 C17 H18 O7 MW: 334.32486000

Identification

Namebyakangelicin
IUPAC9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxyfuro[3,2-g]chromen-7-one
CAS Number482-25-7
FDA UNIILE80Z850I1
Molecular FormulaC17 H18 O7
Molecular Weight334.32486000
MDL NumberMFCD00468051
Nikkaji NumberJ14.808C

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 421.7 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for byakangelicin usage levels up tonot for fragrance use.
Recommendation for byakangelicin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

angelica dahurica lemon fruit oil lemon oil

Synonyms

byak-angelicin (R)-9-(2,3- dihydroxy-3-methylbutoxy)-4-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one 9-[(2R)-2,3- dihydroxy-3-methylbutoxy]-4-methoxyfuro[3,2-g]chromen-7-one 7H- furo(3,2-g)(1)benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)- PubMed: Spectrum Effect Relationship and Component Knock-Out in Angelica Dahurica Radix by High Performance Liquid Chromatography-Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer. PubMed: Coumarins from the roots of Angelica dahurica cause anti-allergic inflammation. PubMed: Simultaneous determination and pharmacokinetics of sixteen Angelicae dahurica coumarins in vivo by LC-ESI-MS/MS following oral delivery in rats. PubMed: [Chemical constituents from polarity part in roots of Angelica dahurica var. formosana cv. Chuanbaizhi]. PubMed: [Chemical constituents from lipophilic parts in roots of Angelica dahurica var. formosana cv. Chuanbaizhi]. PubMed: [Quantitative determination of three active ingredients for quality evaluation of Angelica dahurica]. PubMed: Separation of chemical constituents from three plant medicines by counter-current chromatography using a three-phase solvent system at a novel ratio. PubMed: [Chemical constituents of Angelica nitida roots]. PubMed: Simultaneous determination of 13 chemical marker compounds in Gwakhyangjeonggi-san, a herbal formula, with validated analytical methods. PubMed: Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery. PubMed: Identification of the absorbed constituents after oral administration of Yuanhu Zhitong prescription extract and its pharmacokinetic study by rapid resolution liquid chromatography/quadrupole time-of-flight. PubMed: Anti-tumor effects of various furocoumarins isolated from the roots, seeds and fruits of Angelica and Cnidium species under ultraviolet A irradiation. PubMed: [Study on the coumarin glucosides of Angelica dahurica]. PubMed: [A new natural product from root of Angelica dahurica cv. Qibaizhi]. PubMed: Biotransformation products of phellopterin by rat liver microsomes and the inhibition on NO production in LPS-activated RAW264.7 cells. PubMed: [Study on absorption ingredients of yuanhuzhitong pill by everted intestinal sac method]. PubMed: Sodium desoxycholate-assisted capillary electrochromatography with methacrylate ester-based monolithic column on fast separation and determination of coumarin analogs in Angelica dahurica extract. PubMed: Simultaneous quantification of 17 constituents from Yuanhu Zhitong tablet using rapid resolution liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry. PubMed: Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes. PubMed: An efficient strategy based on MAE, HPLC-DAD-ESI-MS/MS and 2D-prep-HPLC-DAD for the rapid extraction, separation, identification and purification of five active coumarin components from Radix Angelicae Dahuricae. PubMed: beta-secretase inhibitory effects of furanocoumarins from the root of Angelica dahurica. PubMed: Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS. PubMed: [Studies on chemical constituents of the roots of Angelica pubescens]. PubMed: [Studies on chemical constituents from fruits of Paliurus ramosissimus]. PubMed: Separation and quantitative analysis of coumarin compounds from Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook. f by pressurized capillary electrochromatography. PubMed: Agents protecting against sepsis from the roots of Angelica dahurica. PubMed: [Studies on quality standards of radix Angelicae dahuricae]. PubMed: Antioxidative activity of furanocoumarins isolated from Angelicae dahuricae. PubMed: Identification of new urinary metabolites of byakangelicin, a component of Angelicae dahuricae Radix, in rats. PubMed: Constituents of Peucedanum zenkeri seeds and their antimicrobial effects. PubMed: Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production. PubMed: [Studies on chemical constituents of Peucedanum medium Dunn var. garcile Dunn ex Shan at Sheh]. PubMed: Crystal structure of byakangelicin (C17H18O7). PubMed: Furocoumarins from Angelica dahurica with hepatoprotective activity on tacrine-induced cytotoxicity in Hep G2 cells. PubMed: Minor furocoumarins of Murraya koenigii. PubMed: Antiproliferative constituents from umbelliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from the root of Angelica japonica. PubMed: Effect of byakangelicin, an aldose reductase inhibitor, on galactosemic cataracts, the polyol contents and Na(+), K(+)ATPase activity in sciatic nerves of strepto-zotocin-induced diabetic rats. PubMed: Histamine-release effectors from Angelica dahurica var. dahurica root. PubMed: Studies on the antitumor-promoting activity of naturally occurring substances. II. Inhibition of tumor-promoter-enhanced phospholipid metabolism by umbelliferous materials. PubMed: Endocrinological studies on plant products. 8. Inhibitory effect of byakangelicin on and presence of sulphydryl group in pregnant mare's serum gonadotropin. PubMed: Endocrinological studies on plant products: VII. Further evidences on the presence of sulphydryl group in human chorionic gonadotropin and mechanism of action of byakangelicin. PubMed: Effect of byakangelicin on placental gonadotropins. PubMed: Endocrinological studies on plant products: V. Effect of byakangelicin on female sex hormones & on fertility of rats.