ledol
1H-cycloprop[e]azulen-4-ol, decahydro-1,1,4,7-tetramethyl-, (1aR,4R,4aS,7R,7aS,7bS)-
Identification
| Name | ledol |
| IUPAC | (1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol |
| CAS Number | 577-27-5 |
| FDA UNII | 99XJ3YS21U |
| Molecular Formula | C15 H26 O |
| Molecular Weight | 222.37142000 |
| Nikkaji Number | J21.647J |
Regulatory
Physical Properties
| Appearance | colorless crystals (est) |
| Assay | 90.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 0.90940 @ 0.00 °C. |
| Refractive Index | 1.46670 @ 0.00 °C. |
| Melting Point | 104.00 to 105.00 °C. @ 760.00 mm Hg |
| Boiling Point | 293.00 to 294.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.000177 mmHg @ 25.00 °C. (est) |
| Flash Point | 254.00 °F. TCC ( 123.33 °C. ) |
| logP (o/w) | 4.838 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ledol usage levels up to | not for fragrance use. |
| Recommendation for ledol flavor usage levels up to | not for flavor use. |
Glentham Life Sciences Ltd
The Chemical, Biochemical & Research Essentials Supplier
Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
Potential Uses
Natural Occurrence
Synonyms
1H-
cycloprop[e]azulen-4-ol, decahydro-1,1,4,7-tetramethyl-, (1aR,4R,4aS,7R,7aS,7bS)-
(1aR- (1aalpha,4alpha,4abeta, 7alpha,7abeta,7balpha))-
decahydro-1,1,4,7-tetramethyl-1H-cycloprop(e)azulen-4-ol
[1aR-(1aa,4a,4ab,7a,7ab,7ba)]-
decahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen-4-ol
(+)-
ledol
ledum camphor
porschcamphor
(1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-
tetramethyldecahydro-1H-cyclopropa[e]azulen-4-ol
PubMed:
Supercritical CO2 extract and essential oil of aerial part of Ledum palustre L. - Chemical composition and anti-inflammatory activity.
PubMed:
Labrador tea - the aromatic beverage and spice: a review of origin, processing and safety.
PubMed:
[GC/MS-based dynamic analysis of Eucalyptus camaldulensis extract on correlation of chromatography-activity against Oncomelania hupensis].
PubMed:
Composition of the essential oil of the Rhododendron tomentosum Harmaja from Estonia.
PubMed:
Chemical and biological evaluation of Hypericum maculatum Crantz essential oil.
PubMed:
Induction of defensive response in Eucalyptus globulus plants and its persistence in vegetative propagation.
PubMed:
Composition and evaluation of the anti-inflammatory and anticancer activities of the essential oil from Annona sylvatica A. St.-Hil.
PubMed:
Composition of seed essential oils of Rhododendron tomentosum.
PubMed:
Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer L. population from Spain.
PubMed:
Chemical composition, antinociceptive and anti-inflammatory effects in rodents of the essential oil of Peperomia serpens (Sw.) Loud.
PubMed:
Intramolecular Diels-Alder reactions using chiral ruthenium Lewis acids and application in the total synthesis of ent-ledol.
PubMed:
Essential oil from aerial parts of of Betonica grandiflora Willd. from Iran.
PubMed:
Chemical composition and mosquito larvicidal activities of Salvia essential oils.
PubMed:
Seasonal variation, chemical composition, and analgesic and antimicrobial activities of the essential oil from leaves of Tetradenia riparia (Hochst.) Codd in southern Brazil.
PubMed:
Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetala, and their main individual constituents.
PubMed:
Birch (Betula spp.) leaves adsorb and re-release volatiles specific to neighbouring plants--a mechanism for associational herbivore resistance?
PubMed:
Chemical and genetic relationships among sage ( Salvia officinalis L.) cultivars and Judean sage ( Salvia judaica Boiss.).
PubMed:
Biotransformation of terpenoids by mammals, microorganisms, and plant-cultured cells.
PubMed:
Leaf surface sesquiterpene alcohols of the potato (Solanum tuberosum) and their influence on colorado beetle (Leptinotarsa decemlineata Say) feeding.
PubMed:
[GC-MS analysis of essential oils from Radix Angelicae Pubescentis].
PubMed:
Volatile oil from Guarea macrophylla ssp. tuberculata: seasonal variation and electroantennographic detection by Hypsipyla grandella.
PubMed:
Chemical composition of the essential oils of Clausena lansium from Hainan Island, China.
PubMed:
The stereochemistry of ledol from Renealmia chrysotrycha: an NMR study.
PubMed:
Sesquiterpenoids and diterpenoids from the Chilean liverwort Lepicolea ochroleuca.
PubMed:
A New Norlupene from the Leaves of Melaleuca leucadendron
PubMed:
Composition and antimicrobial activity of the essential oil of Cistus creticus subsp. eriocephalus.
PubMed:
Bridged to Fused Ring Interchange. Methodology for the Construction of Fused Cycloheptanes and Cyclooctanes. Total Syntheses of Ledol, Ledene, and Compressanolide.
PubMed:
Composition of essential oil of Ledum palustre.
PubMed:
Chemical studies of marine invertebrates. XXVII. On the absolute configuration of aromadendrane sesquiterpenes from the soft coral Cespitularia aff. subviridis.