dextro,laevo-isoleucine

DL-isoleucine

CAS: 443-79-8 C6 H13 N O2 MW: 131.17501000 odorless bitter

Identification

Namedextro,laevo-isoleucine
IUPAC2-amino-3-methylpentanoic acid
CAS Number443-79-8
EINECS207-139-8
FDA UNII5HX0BYT4E3
Molecular FormulaC6 H13 N O2
Molecular Weight131.17501000
MDL NumberMFCD00004268
Nikkaji NumberJ1.283A
Beilstein1721790
CoE Number10127
XlogP3-1.70 (est)

Regulatory

JECFA Food Flavoring1422 DL-isoleucine
DG SANTE Food Flavourings17.010 DL-isoleucine
FEMA Number3295
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)443-79-8 ; DL-ISOLEUCINE

Physical Properties

Appearance white crystalline powder (est)
Assay 98.00 to 100.00 sum of isomers
Food Chemicals Codex Listed Yes
Melting Point 290.00 to 292.00 °C. @ 760.00 mm Hg
Boiling Point 225.00 to 226.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.031000 mmHg @ 25.00 °C. (est)
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 0.799 (est)
Soluble in water, 2.191e+004 mg/L @ 25 °C (est)
Insoluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantistatic agents

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.
Taste Description bitter

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspecial dietary and nutritional additives
Recommendation for dextro,laevo-isoleucine usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)5.20 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

antistatic agents hair conditioning skin conditioning

Natural Occurrence

not found in nature

Synonyms

acetic acid, amino-sec-butyl- 2- amino-3-methyl pentanoic acid 2- amino-3-methyl valeric acid (±)-2- amino-3-methylpentanoic acid (±)-erythro-2- amino-3-methylpentanoic acid 2- amino-3-methylpentanoic acid DL-2- amino-3-methylpentanoic acid 2- amino-3-methylvaleric acid DL-2- amino-3-methylvaleric acid alpha- amino-beta-methyl valeric acid (±)-iso leucine dextro,laevo-allo-iso leucine dextro,laevo-iso leucine DL-allo-iso leucine DL-iso leucine iso leucine pentanoic acid, 2-amino-3-methyl- valeric acid, 2-amino-3-methyl- PubMed: Linear-dichroic infrared spectroscopy - validation and experimental design of the new orientation technique of solid samples as suspension in nematic liquid crystal. PubMed: Analysis of the loading and hydroxylation steps in lankamycin biosynthesis in Streptomyces rochei. PubMed: Structural relationships in crystals accommodating different stereoisomers of 2-amino-3-methylpentanoic acid. PubMed: Stereoconfiguration of anteiso-fatty biosynthesized from DL-isoleucine in rat skin. PubMed: Soft agar colony formation of bladder cells during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine and application to detection of bladder cancer promoters. PubMed: Preparation of Tc 99m-Sn-thioglycolic acid-dl-isoleucine (Tc-99m-TGA-ILEU) complex and its comparison with Tl 201-chloride for myocardial imaging. PubMed: Anti-inflammatory and analgesic properties of four amino-acids. PubMed: Comparative utilization of the alpha-keto and D- and L-alpha-hydroxy analogs of leucine, isoleucine and valine by chicks and rats. PubMed: Effect of different concentrations of dl-isoleucine, dl-valine, and dl-alanine on growth and sporulation in Fusarium oxysporum f. udum (Butl.) Sn. et H. PubMed: Influence of isoleucine upon quinomycin biosynthesis by Streptomyces sp. 732. PubMed: Amino Acid and vitamin requirements of several bacteroides strains. PubMed: NUTRITIONAL AND REGULATORY ASPECTS OF SERINE METABOLISM IN ESCHERICHIA COLI. PubMed: Nitrogenous compounds in germination and postgerminative development of Bacillus megaterium spores. PubMed: THE EFFECT OF dl-METHIONINE, l-CYSTINE, AND dl-ISOLEUCINE ON THE UTILIZATION OF PARENTERALLY ADMINISTERED DOG HEMOGLOBIN : A SUGGESTION FOR DESIGNING THE COMPOSITION OF THE "IDEAL" PROTEIN DIGEST. PubMed: PLASMA SUBSTITUTES : HUMAN AND ANIMAL GLOBIN RELATED TO THE PRODUCTION OF HEMOGLOBIN AND PLASMA PROTEIN DOG HEMOGLOBIN UTILIZATION IMPROVED BY METHIONINE BUT NOT BY ISOLEUCINE. PubMed: Dog hemoglobin parenterally well utilized to maintain weight and nitrogen balance; utilization improved by dl-methionine but not by dl-isoleucine. PubMed: PLASMA PROTEIN PRODUCTION INFLUENCED BY AMINO ACID MIXTURES AND LACK OF ESSENTIAL AMINO ACIDS : A DEFICIENCY STATE RELATED TO UNKNOWN FACTORS. PubMed: TOLERANCE TO AMINO ACID MIXTURES AND CASEIN DIGESTS GIVEN INTRAVENOUSLY : GLUTAMIC ACID RESPONSIBLE FOR REACTIONS. PubMed: AMINO ACID MIXTURES EFFECTIVE PARENTERALLY FOR LONG CONTINUED PLASMA PROTEIN PRODUCTION. CASEIN DIGESTS COMPARED.