laevo-menthol

cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)- cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,3R,4S)- L- hexahydrothymol laevo- hexahydrothymol levomenthol L- menthacamphor laevo- menthacamphor (1R,3R,4S)-4- menthan-3-ol (-)-trans-p- menthan-cis-ol (-)-trans-para- menthan-cis-ol (1R,3R,4S)-4- menthane-3-ol (-)-trans-p- menthane-cis-ol (-)-trans-para- menthane-cis-ol (-)-(1R,2S,5R)- menthol (1R,2S,5R)-(-)- menthol D-(-)- menthol L- menthol L-(-)- menthol nat.L- menthol (-)- menthol (GC) ≥99% (sum of enantiomers) laevo- menthol (molten 99.5%) laevo- menthol (natural) L- menthol (pellets) synth. FCC L- menthol 98% up, japan pharmacopeia grade L- menthol cryst. nat. menthol crystal Ip/Bp/Usp/Ep/Jp L- menthol crystal, natural, chinese L- menthol crystals organic menthol crystals menthol crystals (codex) (ex mint) menthol crystals chinese menthol crystals indian L- menthol crystals USP natural laevo- menthol crystals USP select FCC (natural) L- menthol crystals USP synthetic L- menthol crystals USP/BP/EP/JP natural menthol ex mint arvensis india organic menthol flake menthol flakes FCC synthetic menthol L- 99.7% synth. menthol L- natural natural menthol large crystals BP/USP natural menthol medium crystals L- menthol natural spray dried menthol natural menthol powder 97.00%.min menthol powder dry BP/USP natural menthol small crystals natural menthol small crystals BP/USP laevo- menthol USP/NF/FCC natural menthol-L dist. menthol-L freeflow menthol-L pellets (US production) menthol-L pellets PH menthol, (1R,3R,4S)-(-)- menthol, natural crystals USP laevo- menthol(USP/BP/NF) (-)-trans-p- methan-cis-3-ol (-)-trans-p- methane-cis-3-ol (1R-(1-alpha,2-beta,5-alpha))-5- methyl-2-(1-methyl ethyl) cyclohexanol (1R-(1-alpha,2-beta,5-alpha))-5- methyl-2-(1-methylethyl)cyclohexanol (1R,2S,5R)-5- methyl-2-(1-methylethyl)cyclohexanol [1R-(1a,2b,5a)]-5- methyl-2-(1-methylethyl)cyclohexanol (1R,2S,5R)-5- methyl-2-(propan-2-yl)cyclohexan-1-ol (1R,2S,5R)-5- methyl-2-(propan-2-yl)cyclohexanol (1R-(1alpha,2beta,5alpha))-5- methyl-2-isopropyl cyclohexanol (1R,2S,5R)-5- methyl-2-propan-2-yl-cyclohexan-1-ol (1R,2S,5R)-5- methyl-2-propan-2-ylcyclohexan-1-ol L- peppermint camphor 1-iso propyl-4-methyl cyclohexan-2-ol (1R,2S,5R)-2-iso propyl-5-methyl-cyclohexanol (1R,2S,5R)-2-iso propyl-5-methylcyclohexanol Info: menthol PubMed: Influence of repeated daily menthol exposure on human temperature regulation and perception. PubMed: A Green and Sustainable Approach: Celebrating the 30th Anniversary of the Asymmetric l-Menthol Process. PubMed: Formulation and evaluation of floating tablet of H2-receptor antagonist. PubMed: Spraying with 0.20% L-menthol does not enhance 5 km running performance in the heat in untrained runners. PubMed: A continuous tri-phase transition effect for HIFU-mediated intravenous drug delivery. PubMed: Somatosensory and vasomotor manifestations of individual and combined stimulation of TRPM8 and TRPA1 using topical L-menthol and trans-cinnamaldehyde in healthy volunteers. PubMed: Prevention of colonic spasm using L-menthol in colonoscopic examination. PubMed: L-menthol improves adenoma detection rate during colonoscopy: a randomized trial. PubMed: Mechanistic investigation and reversible effect of 2-isopropyl-5-methylcyclohexyl heptanoate on the in vitro percutaneous absorption of indomethacin. PubMed: Synthesis and quantitative analysis of diastereomeric linked ester conjugates with remote stereocenters using high-field NMR and chiral HPLC. PubMed: A combination of site-directed mutagenesis and chemical modification to improve diastereopreference of Pseudomonas alcaligenes lipase. PubMed: A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia. PubMed: Structure-activity relationships of monoterpenes and acetyl derivatives against Aedes aegypti (Diptera: Culicidae) larvae. PubMed: A novel animal model of dysphagia following stroke. PubMed: TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain. PubMed: Enantioselective hydrolysis of dl-menthyl benzoate by cell-free extract of newly isolated Acinetobacter sp. ECU2040. PubMed: Efficacy of spraying l-menthol solution during endoscopic treatment of early gastric cancer: a phase III, multicenter, randomized, double-blind, placebo-controlled study. PubMed: The effect of inhaled menthol on upper airway resistance in humans: a randomized controlled crossover study. PubMed: The effects of menthol on cold allodynia and wind-up-like pain in upper limb amputees with different levels of phantom limb pain. PubMed: Thermal grill-evoked sensations of heat correlate with cold pain threshold and are enhanced by menthol and cinnamaldehyde. PubMed: Menthosomes, novel ultradeformable vesicles for transdermal drug delivery: optimization and characterization. PubMed: Topical hindpaw application of L-menthol decreases responsiveness to heat with biphasic effects on cold sensitivity of rat lumbar dorsal horn neurons. PubMed: Lack of effect of menthol level and type on smokers' estimated mouth level exposures to tar and nicotine and perceived sensory characteristics of cigarette smoke. PubMed: Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy. PubMed: A dual catalyst system provides the shortest pathway for L-menthol synthesis. PubMed: Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type. PubMed: Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation. PubMed: Body regional influences of L-menthol application on the alleviation of heat strain while wearing firefighter's protective clothing. PubMed: Properties of gastroretentive sustained release tablets prepared by combination of melt/sublimation actions of L-menthol and penetration of molten polymers into tablets. PubMed: Direct GC analysis of the fatty acid compositions of conjugated linoleic acid and its L-menthyl esters. PubMed: An open-label, single-arm study assessing the efficacy and safety of L: -menthol sprayed onto the gastric mucosa during upper gastrointestinal endoscopy. PubMed: A phase I study evaluating tolerability, pharmacokinetics, and preliminary efficacy of L-menthol in upper gastrointestinal endoscopy. PubMed: Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferation. PubMed: Topical high-concentration (40%) menthol-somatosensory profile of a human surrogate pain model. PubMed: The stereoisomers of menthol in selected tobacco products. A brief report. PubMed: Antiperistaltic effect and safety of L-menthol sprayed on the gastric mucosa for upper GI endoscopy: a phase III, multicenter, randomized, double-blind, placebo-controlled study. PubMed: Effect of (E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate on transdermal delivery of Aconitum alkaloids. PubMed: Different effects of l- and d-menthol on the microstructure of ceramide 5/cholesterol/palmitic acid bilayers. PubMed: A statistical approach to the development of a transdermal delivery system for ondansetron. PubMed: Feasibility of transdermal delivery of prochlorperazine. PubMed: An efficient bioprocess for enzymatic production of L-menthol with high ratio of substrate to catalyst using whole cells of recombinant E. coli. PubMed: The influence of menthol on thermoregulation and perception during exercise in warm, humid conditions. PubMed: Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats. PubMed: Lidocaine/L-menthol binary system: cocrystallization versus solid-state immiscibility. PubMed: Efficacy and safety profile of a topical methyl salicylate and menthol patch in adult patients with mild to moderate muscle strain: a randomized, double-blind, parallel-group, placebo-controlled, multicenter study. PubMed: Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers. PubMed: Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase. PubMed: Erythema multiforme-like generalized contact dermatitis to l-menthol contained in anti-inflammatory medical compresses as an ingredient. PubMed: The effects of swilling an L(-)-menthol solution during exercise in the heat. PubMed: Skin disposition of d-camphor and l-menthol alone and together. PubMed: Effect of l-menthol on the thermotropic behavior of ceramide 2/cholesterol mixtures as a model for the intercellular lipids in stratum corneum. PubMed: Transdermal delivery of tolterodine by O-acylmenthol: In vitro/in vivo correlation. PubMed: Effect of penetration enhancers on transdermal delivery of propofol. PubMed: Menthol and geraniol biotransformation and glycosylation capacity of Levisticum officinale hairy roots. PubMed: Design and in vivo evaluation of an indapamide transdermal patch. PubMed: Formulation optimization of an indomethacin-containing photocrosslinked polyacrylic acid hydrogel as an anti-inflammatory patch. PubMed: Identification of degradation products in loxoprofen sodium adhesive tapes by liquid chromatography-mass spectrometry and dynamic pressurized liquid extraction-solid-phase extraction coupled to liquid chromatography-nuclear magnetic resonance spectroscopy. PubMed: [Advantages of the L-menthol test in assessing chronic nasal obstruction]. PubMed: Impact of menthol inhalation on nasal mucosal temperature and nasal patency. PubMed: Fragrance material review on l-menthol. PubMed: Fragrance material review on d,l-menthol. PubMed: Essential oil of lavender inhibited the decreased attention during a long-term task in humans. PubMed: Differential transfer of dietary flavour compounds into human breast milk. PubMed: Transdermal delivery of valsartan: I. Effect of various terpenes. PubMed: Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives. PubMed: Esters of pyromellitic acid. Part II. Esters of chiral alcohols: para pyromellitate diesters as a novel class of resolving agents and use of pyromellitates as duplicands for chiral purification. PubMed: Expression of Fos protein in brainstem after application of l-menthol to the rat nasal mucosa. PubMed: Insecticidal activity of menthol derivatives against mosquitoes. PubMed: Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers. PubMed: Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity. PubMed: Fragrance release from the surface of branched poly (amide)s. PubMed: Effects of dimethylformamide and L-menthol permeation enhancers on transdermal delivery of quercetin. PubMed: Effects of ethanol/l-menthol on the dynamics and partitioning of spin-labeled lipids in the stratum corneum. PubMed: Characteristic component odors emerge from mixtures after selective adaptation. PubMed: Thermal and nociceptive sensations from menthol and their suppression by dynamic contact. PubMed: Efficient asymmetric synthesis of novel gastrin receptor antagonist AG-041R via highly stereoselective alkylation of oxindole enolates. PubMed: Combined effects of ethanol and L-menthol on hairless rat stratum corneum investigated by synchrotron X-ray diffraction. PubMed: Enhanced skin permeation of salicylate by ion-pair formation in non-aqueous vehicle and further enhancement by ethanol and l-menthol. PubMed: Psychophysical study of the effects of topical application of menthol in healthy volunteers. PubMed: Formulation and evaluation of ethylene-vinyl acetate copolymer matrix patches containing formoterol fumarate. PubMed: Effects of solvents on skin permeation of formoterol fumarate. PubMed: Cold sensitivity in axotomized fibers of experimental neuromas in mice. PubMed: Effects of upper airway anaesthesia on respiratory-related evoked potentials in humans. PubMed: Enzymatic synthesis of l-menthyl alpha-maltoside and l-menthyl alpha-maltooligosides from l-menthyl alpha-glucoside by cyclodextrin glucanotransferase. PubMed: Alpha-anomer-selective glucosylation of menthol with high yield through a crystal accumulation reaction using lyophilized cells of Xanthomonas campestris WU-9701. PubMed: TRPM8 protein localization in trigeminal ganglion and taste papillae. PubMed: Psychophysical isolation of the modality responsible for detecting multimodal stimuli: a chemosensory example. PubMed: [Synthetical evaluation of promoting effect of some kinds of transdermal enhancers with grey relational cluster method]. PubMed: The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes. PubMed: Effect of L-menthol and 1,8-cineole on phase behavior and molecular organization of SC lipids and skin permeation of zidovudine. PubMed: Synthesis and characterization of fluorescent poly(aromatic amide) dendrimers. PubMed: Evaluation of percutaneous absorption of midazolam by terpenes. PubMed: Synthesis, absolute configuration and biological activities of both enantiomers of 2-(5,7-Dichloro-3-indolyl)propionic acid: a novel dichloroindole auxin and antiauxin. PubMed: Flavor release and perception in hard candy: influence of flavor compound-flavor solvent interactions. PubMed: Flavor release and perception in hard candy: influence of flavor compound-compound interactions. PubMed: Origin of chiral induction in radical reactions with the diastereoisomers (5R)- and (5S)-5-l-menthyloxyfuran-2[5H]-one. PubMed: Topical menthol--a human model for cold pain by activation and sensitization of C nociceptors. PubMed: Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac. PubMed: Comparison of skin permeation enhancement by 3-l-menthoxypropane-1,2-diol and l-menthol: the permeation of indomethacin and antipyrine through Yucatan micropig skin and changes in infrared spectra and X-ray diffraction patterns of stratum corneum. PubMed: Lytic activity of l-menthol derivatives against the snow blight disease fungus, Micronectriella nivalis. PubMed: Autonomic nervous system responses to odours: the role of pleasantness and arousal. PubMed: Elevation of plasma levels of L-dopa in transdermal administration of L-dopa-butylester in rats. PubMed: In vitro skin permeation of morphine hydrochloride during the finite application of penetration-enhancing system containing water, ethanol and l-menthol. PubMed: Molecular-imprinted, polymer-coated quartz crystal microbalances for the detection of terpenes. PubMed: Effect of pH on skin permeation enhancement of acidic drugs by l-menthol-ethanol system. PubMed: Oral irritant properties of menthol: sensitizing and desensitizing effects of repeated application and cross-desensitization to nicotine. PubMed: [Does the inhalation of a 1% L-menthol solution in the premedication of fiberoptic bronchoscopy affect coughing and the sensation of dyspnea?]. PubMed: Preparation of griseofulvin for topical application using N-methyl-2-pyrrolidone. PubMed: Physicochemical studies of lidocaine-menthol binary systems for enhanced membrane transport. PubMed: Effect of l-menthol-ethanol-water system on the systemic absorption of flurbiprofen after repeated topical applications in rabbits. PubMed: Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying. PubMed: Whisker growth of l-menthol in coexistence with various excipients. PubMed: l-Menthol-induced [Ca2+]i increase and impulses in cultured sensory neurons. PubMed: Effects of branched cyclodextrins on the solubility and stability of terpenes. PubMed: Effect of synthesized cyclohexanol derivatives using L-menthol as a lead compound on the percutaneous absorption of ketoprofen. PubMed: Transbuccal permeation of a nucleoside analog, dideoxycytidine: effects of menthol as a permeation enhancer. PubMed: Analysis of skin disposition of flurbiprofen after topical application in hairless rats. PubMed: Disposition kinetics and effects of menthol. PubMed: Effect of chiral enhancers on the permeability of optically active and racemic metoprolol across hairless mouse skin. PubMed: The posterior nasal nerve plays an important role on cardiopulmonary reflexes to nasal application of capsaicin, distilled water and l-menthol in anesthetized dogs. PubMed: Effects of removal of stratum corneum, delipidization and addition of enhancers, ethanol and l-menthol, on skin permeation of benzoic acid and its 4-n-alkyl substituents in excised guinea pig dorsal skin. PubMed: The anti-inflammatory activity of L-menthol compared to mint oil in human monocytes in vitro: a novel perspective for its therapeutic use in inflammatory diseases. PubMed: Transdermal absorption of L-dopa from hydrogel in rats. PubMed: Development and in vitro evaluation of nimodipine transdermal formulations using factorial design. PubMed: Determination of l-menthol in pharmaceutical products by high performance liquid chromatography with polarized photometric detection. PubMed: Anomer-selective glucosylation of l-menthol by yeast alpha-glucosidase. PubMed: Racemate and enantiomers of ketoprofen: phase diagram, thermodynamic studies, skin permeability, and use of chiral permeation enhancers. PubMed: Effect of several hydrophilic polymers on the permeation of morphine and salicylic acid through excised hairless rat skin. PubMed: Identification of the L-menthol binding site in guinea-pig lung membranes. PubMed: Effect of menthol and related terpenes on the percutaneous absorption of propranolol across excised hairless mouse skin. PubMed: Skin permeation of parabens in excised guinea pig dorsal skin, its modification by penetration enhancers and their relationship with n-octanol/water partition coefficients. PubMed: 13-week inhalation toxicity study of menthol cigarette smoke. PubMed: Nasal inhalation of l-menthol reduces respiratory discomfort associated with loaded breathing. PubMed: The effect of L-menthol stimulation of the major palatine nerve on subjective and objective nasal patency. PubMed: Nasal receptors responding to cold and l-menthol airflow in the guinea pig. PubMed: Sensitization and desensitization to capsaicin and menthol in the oral cavity: interactions and individual differences. PubMed: l-Menthol, oleic acid and lauricidin in absorption enhancement of free and sodium salt of diclofenac using ethanol treated silicone membrane as model for skin. PubMed: Preparation and stability testing of a hydrogel for topical analgesia. PubMed: [Antinociceptive effects of counterirritants]. PubMed: Metabolic fate of [3H]-l-menthol in the rat. PubMed: The antitussive effects of menthol, camphor and cineole in conscious guinea-pigs. PubMed: Determination of menthol in honey by gas chromatography. PubMed: Influence of composition of l-menthol-ethanol-water ternary solvent system on the transdermal delivery of morphine hydrochloride. PubMed: Effect of pretreatment of skin with cyclic monoterpenes on permeation of diclofenac in hairless rat. PubMed: Feasibility of use of several cardiovascular agents in transdermal therapeutic systems with l-menthol-ethanol system on hairless rat and human skin. PubMed: Effect of l-menthol on the permeation of indomethacin, mannitol and cortisone through excised hairless mouse skin. PubMed: Menthol in the upper airway depresses ventilation in newborn dogs. PubMed: The sensory effects of l-menthol on human skin. PubMed: Effects of l-menthol and dl-camphor on the penetration and hydrolysis of methyl salicylate in hairless mouse skin. PubMed: Combined effect of cyclic monoterpenes and ethanol on percutaneous absorption of diclofenac sodium. PubMed: Upper airway cooling and l-menthol reduce ventilation in the guinea pig. PubMed: Effect of l-menthol on laryngeal receptors. PubMed: The effect of L-menthol stimulation of the major palatine nerve on nasal patency. PubMed: Effect of cyclic monoterpenes on percutaneous absorption in the case of a water-soluble drug (diclofenac sodium). PubMed: Immobilization of lipase from Candida cylindraceae and its use in the synthesis of menthol esters by transesterification. PubMed: Percutaneous absorption enhancing effect and skin irritation of monocyclic monoterpenes. PubMed: Two-phase system membrane reactor with cofactor recycling. PubMed: The effects of menthol on reaction time and nasal sensation of airflow in subjects suffering from the common cold. PubMed: Olfactory and trigeminal thresholds and nasal resistance to airflow. PubMed: Chromosomal aberrations and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals. PubMed: Studies on the metabolism of l-menthol in rats. PubMed: The effects of D and L isomers of menthol upon nasal sensation of airflow. PubMed: The effects of menthol isomers on nasal sensation of airflow. PubMed: Menthol inhibits the perception of warmth. PubMed: Menthol modulates oral sensations of warmth and cold. PubMed: Metabolism of Monoterpenes : Early Steps in the Metabolism of d-Neomenthyl-beta-d-Glucoside in Peppermint (Mentha piperita) Rhizomes. PubMed: Receptor cell responses to odorants: similarities and differences among odorants. PubMed: Demonstration that limonene is the first cyclic intermediate in the biosynthesis of oxygenated p-menthane monoterpenes in Mentha piperita and other Mentha species. PubMed: Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves. PubMed: Demonstration of the Intercellular Compartmentation of l-Menthone Metabolism in Peppermint (Mentha piperita) Leaves. PubMed: Metabolism of Monoterpenes : EVIDENCE FOR COMPARTMENTATION OF l-MENTHONE METABOLISM IN PEPPERMINT (MENTHA PIPERITA) LEAVES. PubMed: Electronic properties of the nitrosamine function. PubMed: Separation of l-menthol from racemic menthol U.S.P.