Synonyms
cyclohex-1-ene-1-methanol, 4-(1-methylethenyl)-
1-
cyclohexene-1-methanol, 4-(1-methylethenyl)
dihydro cuminyl alcohol
hydrocumin alcohol
1-
hydroxymethyl-4-isopropenyl-1-cyclohexene
p-
mentha-1,8-dien-7-ol
para-
mentha-1,8-dien-7-ol
menthadien-7-carbinol
1,8-p-
menthadien-7-ol
4-(1-
methyl ethenyl)-1-cyclohexene-1-methanol
[4-(1-
methylethenyl)-1-cyclohexen-1-yl]methanol
4-(1-
methylethenyl)-1-cyclohexene-1-methanol
perillic alcohol
perillol
(4-
prop-1-en-2-yl-1-cyclohexenyl)methanol
[4-(
prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol
4-iso
propenyl cyclohex-1-en-1-yl methanol
4-iso
propenyl cyclohex-1-ene-1-methanol
4-iso
propenyl cyclohex-1-enyl methanol
(4-iso
propenyl-1-cyclohexen-1-yl)methanol
4-iso
propenyl-1-cyclohexene carbinol
4-iso
propenyl-1-cyclohexenecarbinol
4-iso
propenyl-1-cyclohexenyl methanol
4-iso
propenyl-cyclohex-1-ene-1-methanol
4-iso
propenyl-cyclohex-1-enylmethanol
4-iso
propenylcyclohex-1-en-1-ylmethanol
4-iso
propenylcyclohex-1-enyl methanol
4-iso
propenylcyclohex-1-enylmethanol
US Patents:
3,993,604 - Alicyclic compounds, their use and process for preparing same
PubMed:
Synthesis and antiproliferative effects of amino-modified perillyl alcohol derivatives.
PubMed:
Gene discovery for enzymes involved in limonene modification or utilization by the mountain pine beetle-associated pathogen Grosmannia clavigera.
PubMed:
Influence of culture conditions on the biotransformation of (+)-limonene by Aspergillus niger.
PubMed:
A Novel Temozolomide-Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells In Vitro and Intracranial Triple-Negative Tumor Growth In Vivo.
PubMed:
A systematic review of inhaled intranasal therapy for central nervous system neoplasms: an emerging therapeutic option.
PubMed:
Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation.
PubMed:
Perillyl alcohol suppresses antigen-induced immune responses in the lung.
PubMed:
Chemical composition and mosquito repellency of essential oil of Conyza newii propagated in different geographical locations of Kenya.
PubMed:
Intranasal administration of perillyl alcohol activates peripheral and bronchus-associated immune system in vivo.
PubMed:
Chemoprevention gene therapy (CGT) of pancreatic cancer using perillyl alcohol and a novel chimeric serotype cancer terminator virus.
PubMed:
Skin repair properties of d-Limonene and perillyl alcohol in murine models.
PubMed:
Anti-stress effects of d-limonene and its metabolite perillyl alcohol.
PubMed:
Influence of GSTM1 and GSTT1 polymorphisms on the survival rate of patients with malignant glioma under perillyl alcohol-based therapy.
PubMed:
eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase.
PubMed:
Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production.
PubMed:
Perillyl alcohol as a protective modulator against rat hepatocarcinogenesis via amelioration of oxidative damage and cell proliferation.
PubMed:
Double reduction of cyclic aromatic sulfonamides: synthesis of (+)-mesembrine and (+)-mesembranol.
PubMed:
4-Bromo-2-(piperidin-1-yl)thiazol-5-yl-phenyl methanone (12b) inhibits Na+/K(+)-ATPase and Ras oncogene activity in cancer cells.
PubMed:
Disruption of an hTERT-mTOR-RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin.
PubMed:
Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL.
PubMed:
Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction.
PubMed:
Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
PubMed:
The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
PubMed:
Chemoprevention of hepatocarcinogenesis with dietary isoprenic derivatives: cellular and molecular aspects.
PubMed:
Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.
PubMed:
Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.
PubMed:
Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium.
PubMed:
Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities.
PubMed:
Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans.
PubMed:
Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.
PubMed:
Influence of the active compounds of Perilla frutescens leaves on lipid membranes.
PubMed:
Nonmelanoma skin cancer chemoprevention.
PubMed:
An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1.
PubMed:
Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.
PubMed:
Evaluation of the antioxidant and antiproliferative potential of bioflavors.
PubMed:
Prevention of transplant coronary artery disease by prenylation inhibitors.
PubMed:
Mechanism of statin-induced contractile dysfunction in rat cultured skeletal myofibers.
PubMed:
Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production.
PubMed:
Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.
PubMed:
Nonsurgical innovations in the treatment of nonmelanoma skin cancer.
PubMed:
The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor.
PubMed:
Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma.
PubMed:
Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids.
PubMed:
The promise of natural products for blocking early events in skin carcinogenesis.
PubMed:
A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.
PubMed:
Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol.
PubMed:
(1S,2R,4S)-1-[(Benzyl-amino)-meth-yl]-4-(prop-1-en-2-yl)cyclo-hexane-1,2-diol.
PubMed:
Pharmacotherapy of actinic keratosis.
PubMed:
Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma.
PubMed:
Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin.
PubMed:
Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system.
PubMed:
Possible contribution of beta-glycosidases and caspases in the cytotoxicity of novel glycoconjugates in colon cancer cells.
PubMed:
[Natural compounds in chemoprevention of esophageal squamous cell tumors--experimental studies].
PubMed:
Components of lemon essential oil attenuate dementia induced by scopolamine.
PubMed:
GO Explorer: A gene-ontology tool to aid in the interpretation of shotgun proteomics data.
PubMed:
Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol.
PubMed:
Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.
PubMed:
Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol.
PubMed:
Gateways to clinical trials.
PubMed:
High-performance liquid chromatographic and pharmacokinetic analyses of an intravenous submicron emulsion of perillyl alcohol in rats.
PubMed:
Sensitive determination of monoterpene alcohols in urine by HPLC-FLD combined with ESI-MS detection after online-solid phase extraction of the monoterpene-coumarincarbamate derivates.
PubMed:
Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.
PubMed:
Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol.
PubMed:
Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.
PubMed:
Fragrance material review on p-mentha-1,8-dien-7-ol.
PubMed:
Discovery of new biocatalysts for the glycosylation of terpenoid scaffolds.
PubMed:
Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
PubMed:
Biphenylalkylacetylhydroquinone ethers suppress the proliferation of murine B16 melanoma cells.
PubMed:
A pilot study of perillyl alcohol in pancreatic cancer.
PubMed:
Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma.
PubMed:
Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer.
PubMed:
Anti-inflammatory senescence actives 5203-L molecule to promote healthy aging and prolongation of lifespan.
PubMed:
Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
PubMed:
Perillyl Alcohol Protects Against Fe-NTA-Induced Nephrotoxicity and Early Tumor Promotional Events in Rat Experimental Model.
PubMed:
Cloning of four genes involved in limonene hydroxylation from Enterobacter cowanii 6L.
PubMed:
Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.
PubMed:
Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer.
PubMed:
Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofibers.
PubMed:
Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells.
PubMed:
Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review.
PubMed:
Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
PubMed:
Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549.
PubMed:
In vitro induction of apoptosis in U937 cells by perillyl alcohol with sensitization by pentoxifylline: increased BCL-2 and BAX protein expression.
PubMed:
Mastic oil from Pistacia lentiscus var. chia inhibits growth and survival of human K562 leukemia cells and attenuates angiogenesis.
PubMed:
Evaluation of characteristic aroma compounds of Citrus natsudaidai Hayata (Natsudaidai) cold-pressed peel oil.
PubMed:
Terpenoids as plant antioxidants.
PubMed:
Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.
PubMed:
Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol.
PubMed:
Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells.
PubMed:
Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.
PubMed:
Gateways to clinical trials.
PubMed:
Regio- and stereoselective fungal oxyfunctionalisation of limonenes.
PubMed:
Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells.
PubMed:
Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo.
PubMed:
CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.
PubMed:
Fumigant toxicity of the essential oils of some African plants against Anopheles gambiae sensu stricto.
PubMed:
Biocatalytic production of perillyl alcohol from limonene by using a novel Mycobacterium sp. cytochrome P450 alkane hydroxylase expressed in Pseudomonas putida.
PubMed:
Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells.
PubMed:
Cancer preventive role of selected dietary factors.
PubMed:
Effect of D-limonene on immune response in BALB/c mice with lymphoma.
PubMed:
An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation.
PubMed:
A novel psychrotrophic fungus, Mortierella minutissima, for D-limonene biotransformation.
PubMed:
Sle1ab mediates the aberrant activation of STAT3 and Ras-ERK signaling pathways in B lymphocytes.
PubMed:
Species differences in the metabolism of (+)- and (-)-limonenes and their metabolites, carveols and carvones, by cytochrome P450 enzymes in liver microsomes of mice, rats, guinea pigs, rabbits, dogs, monkeys, and humans.
PubMed:
Clinical trials in cancer prevention: current results and perspectives for the future.
PubMed:
A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia.
PubMed:
R-(+)-perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34(cdc2) expression in colonic adenocarcinoma SW480 cells.
PubMed:
Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro.
PubMed:
Repellency of essential oils of some Kenyan plants against Anopheles gambiae.
PubMed:
Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.
PubMed:
Perillyl alcohol is an angiogenesis inhibitor.
PubMed:
A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.
PubMed:
Effects of POH in combination with STI571 on the proliferation and apoptosis of K562 cells.
PubMed:
Antinociceptive effects of the essential oil of Dracocephalum kotschyi in the mouse writhing test.
PubMed:
Gateways to clinical trials.
PubMed:
Using patients as their own controls for cost evaluation of phase I clinical trials.
PubMed:
Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo.
PubMed:
Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.
PubMed:
Transformation of terpenes using a Picea abies suspension culture.
PubMed:
Development of a perillyl alcohol topical cream formulation.
PubMed:
Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.
PubMed:
Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer.
PubMed:
Gateways to clinical trials.
PubMed:
Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion.
PubMed:
Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia.
PubMed:
Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells.
PubMed:
Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro.
PubMed:
Phase I trial of perillyl alcohol administered four times daily continuously.
PubMed:
Skin cancer chemoprevention: strategies to save our skin.
PubMed:
Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells.
PubMed:
In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry.
PubMed:
Perillyl alcohol as a radio-/chemosensitizer in malignant glioma.
PubMed:
Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer.
PubMed:
Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
PubMed:
Biotransformation of limonene by bacteria, fungi, yeasts, and plants.
PubMed:
A phase I trial of perillyl alcohol in patients with advanced solid tumors.
PubMed:
Monoterpene regulation of Ras and Ras-related protein expression.
PubMed:
Mechanism-based in vitro screening of potential cancer chemopreventive agents.
PubMed:
Micronutrients in cancer chemoprevention.
PubMed:
Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
PubMed:
Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level.
PubMed:
Perillyl Alcohol Inhibits Breast Cell Migration without Affecting Cell Adhesion.
PubMed:
Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.
PubMed:
Sensitive biomonitoring of monoterpene exposure by gas chromatographic-mass spectrometric measurement of hydroxy terpenes in urine.
PubMed:
Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.
PubMed:
Phase I study of perillyl alcohol in patients with refractory malignancies.
PubMed:
A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96.
PubMed:
Effects of perillyl alcohol on melanoma in the TPras mouse model.
PubMed:
Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
PubMed:
Weight-loss drugs and supplements: are there safer alternatives?
PubMed:
Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
PubMed:
Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes.
PubMed:
Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.
PubMed:
Biotransformation of limonene by Pseudomonas putida.
PubMed:
Chemopreventive efficacy of promising farnesyltransferase inhibitors.
PubMed:
Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note.
PubMed:
Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.
PubMed:
Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat.
PubMed:
The state-of-the-art in chemoprevention of skin cancer.
PubMed:
Cloning and expression of the limonene hydroxylase of Bacillus stearothermophilus BR388 and utilization in two-phase limonene conversions.
PubMed:
Perillyl alcohol inhibits TCR-mediated [Ca(2+)](i) signaling, alters cell shape and motility, and induces apoptosis in T lymphocytes.
PubMed:
Prenylation inhibitors to treat proliferative renal disease.
PubMed:
Correlation of chemopreventive efficacy data from the human epidermal cell assay with in vivo data.
PubMed:
Progress in cancer chemoprevention: development of diet-derived chemopreventive agents.
PubMed:
Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day.
PubMed:
Perillyl alcohol, an inhibitor of geranylgeranyl transferase, induces apoptosis of immortalized human vascular smooth muscle cells in vitro.
PubMed:
Progress in cancer chemoprevention.
PubMed:
Drug development in prostate cancer.
PubMed:
Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abl-transformed myeloid cell lines.
PubMed:
Induction of AP-1 activity by perillyl alcohol in breast cancer cells.
PubMed:
Enhancement of sterol synthesis by the monoterpene perillyl alcohol is unaffected by competitive 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
PubMed:
Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma.
PubMed:
Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.
PubMed:
Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors.
PubMed:
Activation of the transforming growth factor beta signaling pathway and induction of cytostasis and apoptosis in mammary carcinomas treated with the anticancer agent perillyl alcohol.
PubMed:
Prevention and therapy of cancer by dietary monoterpenes.
PubMed:
Inhibition of protein prenylation by metabolites of limonene.
PubMed:
Insulin promotes phosphorylation and activation of geranylgeranyltransferase II. Studies with geranylgeranylation of rab-3 and rab-4.
PubMed:
Perillyl alcohol: applications in oncology.
PubMed:
Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines.
PubMed:
Modulation of small G protein isoprenylation by anticancer monoterpenes in in situ mammary gland epithelial cells.
PubMed:
Effects of the antitumor agent perillyl alcohol on H-Ras vs. K-Ras farnesylation and signal transduction in pancreatic cells.
PubMed:
Phase I clinical trial of perillyl alcohol administered daily.
PubMed:
Monoterpenes in breast cancer chemoprevention.
PubMed:
Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation.
PubMed:
Quantification of carvone, cineole, perillaldehyde, perillyl alcohol and sobrerol by isocratic high-performance liquid chromatography.
PubMed:
Clinical trials referral resource. Clinical trials with perillyl alcohol.
PubMed:
Lysophosphatidic acid stimulates phospholipase D activity and cell proliferation in PC-3 human prostate cancer cells.
PubMed:
Modulation of RAS expression in human malignant cells by dietary supplements.
PubMed:
Induction of the apoptosis-promoting protein Bak by perillyl alcohol in pancreatic ductal adenocarcinoma relative to untransformed ductal epithelial cells.
PubMed:
Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells.
PubMed:
Total Synthesis of the Enantiomer of the Furanocembrane Rubifolide.
PubMed:
Cancer chemoprevention and therapy by monoterpenes.
PubMed:
Composition and antimalarial activity in vitro of the essential oil of Tetradenia riparia.
PubMed:
Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo.
PubMed:
Oral monoterpene therapy (perillyl alcohol) reduces vein graft intimal hyperplasia.
PubMed:
Production of alpha-terpineol from Escherichia coli cells expressing thermostable limonene hydratase.
PubMed:
Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol.
PubMed:
Chemoprevention of colon carcinogenesis by dietary perillyl alcohol.
PubMed:
Analysis of perillic acid in plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
PubMed:
Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung.
PubMed:
Prevention of mammary preneoplastic transformation by naturally-occurring tumor inhibitors.
PubMed:
Inhibition of metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by limonene.
PubMed:
Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action.
PubMed:
Chemoprevention of breast cancer.
PubMed:
Clinical development plan: l-perillyl alcohol.
PubMed:
Strategy and planning for chemopreventive drug development: clinical development plans II.
PubMed:
New agents for cancer chemoprevention.
PubMed:
Monoterpenes as regulators of malignant cell proliferation.
PubMed:
Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.
PubMed:
Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo.
PubMed:
Genetic and cellular changes in colorectal cancer: proposed targets of chemopreventive agents.
PubMed:
Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol.
PubMed:
Induction of differentiation in neuro-2A cells by the monoterpene perillyl alcohol.
PubMed:
Promoting apoptosis.
PubMed:
Differential effects of monoterpenes and lovastatin on RAS processing.
PubMed:
Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, an investigational antineoplastic agent, to the dog.
PubMed:
Isoprenylation of proteins in the protozoan Giardia lamblia.
PubMed:
The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol.
PubMed:
Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol.
PubMed:
Prevention and therapy of mammary cancer by monoterpenes.
PubMed:
The chemoprevention of cancer by mevalonate-derived constituents of fruits and vegetables.
PubMed:
Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation.
PubMed:
Growth inhibition of rat liver epithelial tumor cells by monoterpenes does not involve Ras plasma membrane association.
PubMed:
Prenylated proteins and lymphocyte proliferation: inhibition by d-limonene related monoterpenes.
PubMed:
Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol.
PubMed:
Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene.
PubMed:
[Constituents of essential oils from leaves, stems, and fruits of Perilla frutescens (L.) Britt].
PubMed:
Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves.
PubMed:
Benzyl alcohol dehydrogenase and benzaldehyde dehydrogenase II from Acinetobacter calcoaceticus. Substrate specificities and inhibition studies.
PubMed:
Metabolism of alpha-terpineol by Pseudomonas incognita.
PubMed:
Monographs on fragrance raw materials.
PubMed:
Microbiological transformations of terpenes. XIV. Purification & properties of perillyl alcohol dehydrogenase.
PubMed:
Perillyl alcohol dehydrogenase from a soil pseudomonad.