chocolate extract
Identification
| Name | chocolate extract |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Organoleptic Properties
| Taste Description | chocolate |
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavored products of all types |
| Recommendation for chocolate extract usage levels up to | not for fragrance use. |
Advanced Biotech. Inc.
Inspired by Nature
A diverse range of products, all meeting our stringent commitment to quality.
Horner International
The finest extracts in the world
Horner International supplies the finest natural extracts and flavors to a world-wide customer base.
FRUTAROM USA INC,
Flavor & Specialty Ingredients
Your preferred partner for flavour and fragrance success.
Potential Uses
Natural Occurrence
Synonyms
chocolate fluid extract
chocolate spray-dried powder extract
PubMed:
Cocoa phenolic extract protects pancreatic beta cells against oxidative stress.
PubMed:
Rapid differentiation of Ghana cocoa beans by FT-NIR spectroscopy coupled with multivariate classification.
PubMed:
Cocoa powder extracts exhibits hypolipidemic potential in cholesterol-fed rats.
PubMed:
Active films based on cocoa extract with antioxidant, antimicrobial and biological applications.
PubMed:
Cocoa powder triggers neuroprotective and preventive effects in a human Alzheimer's disease model by modulating BDNF signaling pathway.
PubMed:
Cocoa flavonoids improve insulin signalling and modulate glucose production via AKT and AMPK in HepG2 cells.
PubMed:
Cocoa husks in diets of Italian heavy pigs.
PubMed:
Reducing effect of an extract of Phaseolus vulgaris on food intake in mice--focus on highly palatable foods.
PubMed:
[Investigation of bacterial etiology with conventional and multiplex PCR methods in adult patients with community-acquired pneumonia].
PubMed:
Cocoa polyphenols prevent inflammation in the colon of azoxymethane-treated rats and in TNF-α-stimulated Caco-2 cells.
PubMed:
Human bioavailability of flavanols and phenolic acids from cocoa-nut creams enriched with free or microencapsulated cocoa polyphenols.
PubMed:
Cocoa polyphenols are absorbed in Caco-2 cell model of intestinal epithelium.
PubMed:
Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
PubMed:
Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.
PubMed:
Preventing Ralstonia solanacearum adhesion with glycans from cashew, cocoa, coffee, pumpkin, and tomato seed extract.
PubMed:
Method for the determination of catechin and epicatechin enantiomers in cocoa-based ingredients and products by high-performance liquid chromatography: single-laboratory validation.
PubMed:
Cocoa polyphenols suppress adipogenesis in vitro and obesity in vivo by targeting insulin receptor.
PubMed:
Modification of ginseng flavors by bitter compounds found in chocolate and coffee.
PubMed:
Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on food intake and glycemia in rats.
PubMed:
Prevention mechanisms of glucose intolerance and obesity by cacao liquor procyanidin extract in high-fat diet-fed C57BL/6 mice.
PubMed:
Selective removal of the violet color produced by anthocyanins in procyanidin-rich unfermented cocoa extracts.
PubMed:
Consumer acceptance of ginseng food products.
PubMed:
Nutrient agar with sodium chloride supplementation for presumptive detection of Moraxella catarrhalis in clinical specimens.
PubMed:
In vitro activity of extract and fractions of natural cocoa powder on Plasmodium falciparum.
PubMed:
A polyphenol-enriched cocoa extract reduces free radicals produced by mycotoxins.
PubMed:
Screening for natural chemoprevention agents that modify human Keap1.
PubMed:
Effect of a cocoa polyphenol extract in spontaneously hypertensive rats.
PubMed:
Comparative evaluation of chlorhexidine mouthrinse versus cacao bean husk extract mouthrinse as antimicrobial agents in children.
PubMed:
Development of an immuno-affinity column for ochratoxin analysis using an organic solvent-tolerant monoclonal antibody.
PubMed:
Inhibitory activity of Asian spices on heterocyclic amines formation in cooked beef patties.
PubMed:
One-PCR-tube approach for in situ DNA isolation and detection.
PubMed:
CYP1A1 is overexpressed upon incubation of breast cancer cells with a polyphenolic cocoa extract.
PubMed:
A new glycosylated dihydrophaseic acid from cacao germs (Theobroma cacao L.).
PubMed:
Botrytone, a new naphthalenone pentaketide produced by Botrytis fabae, the causal agent of chocolate spot disease on Vicia faba.
PubMed:
A comprehensive evaluation of the toxicology of cigarette ingredients: cocoa-derived ingredients.
PubMed:
Determination of the cyanobacterial toxin cylindrospermopsin in algal food supplements.
PubMed:
Inhibition of ulcerative colitis in mice after oral administration of a polyphenol-enriched cocoa extract is mediated by the inhibition of STAT1 and STAT3 phosphorylation in colon cells.
PubMed:
Human basophils: a unique biological instrument to detect the allergenicity of food.
PubMed:
Inhibition of key digestive enzymes by cocoa extracts and procyanidins.
PubMed:
On the taste of "Bouba" and "Kiki": An exploration of word-food associations in neurologically normal participants.
PubMed:
Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway.
PubMed:
Determination of roasted pistachio (Pistacia vera L.) key odorants by headspace solid-phase microextraction and gas chromatography-olfactometry.
PubMed:
A new arginase enzymatic reactor: development and application for the research of plant-derived inhibitors.
PubMed:
Cacao seeds are a "Super Fruit": A comparative analysis of various fruit powders and products.
PubMed:
Effects of cocoa extract and dark chocolate on angiotensin-converting enzyme and nitric oxide in human endothelial cells and healthy volunteers--a nutrigenomics perspective.
PubMed:
The effect of nutrition on blood pressure.
PubMed:
Cocoa polyphenols suppress TNF-α-induced vascular endothelial growth factor expression by inhibiting phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase kinase-1 (MEK1) activities in mouse epidermal cells.
PubMed:
Physical properties and bioactive constituents of powdered mixtures and drinks prepared with cocoa and various sweeteners.
PubMed:
Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.
PubMed:
Reducing effect of a Phaseolus vulgaris dry extract on operant self-administration of a chocolate-flavoured beverage in rats.
PubMed:
Acute Treatment With Herbal Extracts Provides Neuroprotective Benefits in In Vitro and In Vivo Stroke Models, Characterized by Reduced Ischemic Cell Death and Maintenance of Motor and Neurological Functions.
PubMed:
Development and validation of an indirect competitive enzyme linked-immunosorbent assay for the determination of potentially allergenic sesame (Sesamum indicum) in food.
PubMed:
Protective activity of Theobroma cacao L. phenolic extract on AML12 and MLP29 liver cells by preventing apoptosis and inducing autophagy.
PubMed:
Towards a platform for the metabonomic profiling of different strains of Drosophila melanogaster using liquid chromatography-Fourier transform mass spectrometry.
PubMed:
Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats.
PubMed:
Dark chocolate or tomato extract for prehypertension: a randomised controlled trial.
PubMed:
Does an extract of carob (Ceratonia siliqua L.) have chemopreventive potential related to oxidative stress and drug metabolism in human colon cells?
PubMed:
Cocoa flavonoids up-regulate antioxidant enzyme activity via the ERK1/2 pathway to protect against oxidative stress-induced apoptosis in HepG2 cells.
PubMed:
Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-gamma-valerolactone as the major metabolites.
PubMed:
Single-drop micro-extraction and diffuse reflectance Fourier transform infrared spectroscopic determination of chromium in biological fluids.
PubMed:
Crude cacao Theobroma cacao extract reduces mutagenicity induced by benzo[a]pyrene through inhibition of CYP1A activity in vitro.
PubMed:
Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress.
PubMed:
Simultaneous determination of theobromine, (+)-catechin, caffeine, and (-)-epicatechin in standard reference material baking chocolate 2384, cocoa, cocoa beans, and cocoa butter.
PubMed:
Antidepressant-like effects of a cocoa polyphenolic extract in Wistar-Unilever rats.
PubMed:
Cacao polyphenol extract suppresses transformation of an aryl hydrocarbon receptor in C57BL/6 mice.
PubMed:
Grape seed procyanidins inhibit the expression of metallothione in genes in human HepG2 cells.
PubMed:
Cocoa polyphenols and their influence on parameters involved in ex vivo skin restructuring.
PubMed:
Obtention and characterization of phenolic extracts from different cocoa sources.
PubMed:
Acetobacter fabarum sp. nov., an acetic acid bacterium from a Ghanaian cocoa bean heap fermentation.
PubMed:
Effects of cocoa extract on glucometabolism, oxidative stress, and antioxidant enzymes in obese-diabetic (Ob-db) rats.
PubMed:
In vitro stability, potency, and dissolution of duloxetine enteric-coated pellets after exposure to applesauce, apple juice, and chocolate pudding.
PubMed:
Protection of human HepG2 cells against oxidative stress by cocoa phenolic extract.
PubMed:
Chocolate mouth rinse: Effect on plaque accumulation and mutans streptococci counts when used by children.
PubMed:
[Investigation of ochratoxin a, B and citrinin contamination in various commercial foods].
PubMed:
Use of response surface methodology to examine chitinase regulation in the basidiomycete Moniliophthora perniciosa.
PubMed:
Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats.
PubMed:
Cacao procyanidins reduce plasma cholesterol and increase fecal steroid excretion in rats fed a high-cholesterol diet.
PubMed:
Therapeutic effect of ACTICOA powder, a cocoa polyphenolic extract, on experimentally induced prostate hyperplasia in Wistar-Unilever rats.
PubMed:
Preventive effects of ACTICOA powder, a cocoa polyphenolic extract, on experimentally induced prostate hyperplasia in Wistar-Unilever rats.
PubMed:
Protective effect of Acticoa powder, a cocoa polyphenolic extract, on prostate carcinogenesis in Wistar-Unilever rats.
PubMed:
Repression of calcitonin gene-related peptide expression in trigeminal neurons by a Theobroma cacao extract.
PubMed:
Preventive antioxidant effects of cocoa polyphenolic extract on free radical production and cognitive performances after heat exposure in Wistar rats.
PubMed:
The antibacterial activity of plant extracts containing polyphenols against Streptococcus mutans.
PubMed:
Acetobacter ghanensis sp. nov., a novel acetic acid bacterium isolated from traditional heap fermentations of Ghanaian cocoa beans.
PubMed:
Standard reference materials for foods and dietary supplements.
PubMed:
In vitro evaluation of alternative oral contrast agents for MRI of the gastrointestinal tract.
PubMed:
Quantification of flavor-related compounds in the unburned contents of bidi and clove cigarettes.
PubMed:
[Characterization of cocoa fiber and its effect on the antioxidant capacity of serum in rats].
PubMed:
Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus.
PubMed:
Characterization of aroma-active compounds in raw and cooked pine-mushrooms (Tricholoma matsutake Sing.).
PubMed:
Identification of the key aroma compounds in cocoa powder based on molecular sensory correlations.
PubMed:
In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human prostate cancer and normal cells.
PubMed:
Analysis of acrylamide in coffee and cocoa by isotope dilution liquid chromatography-tandem mass spectrometry.
PubMed:
Determination of acrylamide in various food matrices: evaluation of LC and GC mass spectrometric methods.
PubMed:
Determination of biogenic amines in chocolate by ion chromatographic separation and pulsed integrated amperometric detection with implemented wave-form at Au disposable electrode.
PubMed:
Flavonoids from Theobroma cacao down-regulate inflammatory mediators.
PubMed:
Polyphenol levels in human urine after intake of six different polyphenol-rich beverages.
PubMed:
Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia.
PubMed:
Quantitation of acrylamide in food products by liquid chromatography/mass spectrometry.
PubMed:
Structures, sensory activity, and dose/response functions of 2,5-diketopiperazines in roasted cocoa nibs (Theobroma cacao).
PubMed:
Effect of Theobroma cacao flavonoids on immune activation of a lymphoid cell line.
PubMed:
Curare: the South American arrow poison.
PubMed:
The effect of Malaysian cocoa extract on glucose levels and lipid profiles in diabetic rats.
PubMed:
Bacteremia in a patient with colonic carcinoma caused by a novel Sedimentibacter species: Sedimentibacter hongkongensis sp. nov.
PubMed:
Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells.
PubMed:
Inhibitory effects of cacao bean husk extract on plaque formation in vitro and in vivo.
PubMed:
Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats.
PubMed:
Determination of ephedrine alkaloids in botanicals and dietary supplements by HPLC-UV: collaborative study.
PubMed:
Anti-cariogenic properties of a water-soluble extract from cacao.
PubMed:
Effect of the number of flavanol units on the antioxidant activity of procyanidin fractions isolated from chocolate.
PubMed:
The effect of herbal remedy on the development of Trichinella spiralis infection in mice.
PubMed:
Benzophenone in cartonboard packaging materials and the factors that influence its migration into food.
PubMed:
Immunochemical-based method for detection of hazelnut proteins in processed foods.
PubMed:
Effects of an aqueous extract of cocoa on nitric oxide production of macrophages activated by lipopolysaccharide and interferon-gamma.
PubMed:
Determination of retinyl palmitate (vitamin A) in fortified fluid milk by liquid chromatography: collaborative study.
PubMed:
The impact of fortification with conjugated linoleic acid (CLA) on the quality of fluid milk.
PubMed:
[Determination of sucralose in foods by liquid chromatography/tandem mass spectrometry].
PubMed:
Lack of in vivo clastogenic activity of grape seed and grape skin extracts in a mouse micronucleus assay.
PubMed:
Cocoa products decrease low density lipoprotein oxidative susceptibility but do not affect biomarkers of inflammation in humans.
PubMed:
Subchronic 3-month oral toxicity study of grape seed and grape skin extracts.
PubMed:
Cocoa extract protects against early alcohol-induced liver injury in the rat.
PubMed:
Chemical evaluation and digestibility of cocoa (Theobroma cacao) byproducts fed to goats.
PubMed:
Inhibitory effects of cocoa flavanols and procyanidin oligomers on free radical-induced erythrocyte hemolysis.
PubMed:
Use of gas chromatography-olfactometry to identify key odorant compounds in dark chocolate. Comparison of samples before and after conching.
PubMed:
Serum IgG response to differentiated antigens of Helicobacter pylori.
PubMed:
Standardization of broth microdilution and disk diffusion susceptibility tests for Actinobacillus pleuropneumoniae and Haemophilus somnus: quality control standards for ceftiofur, enrofloxacin, florfenicol, gentamicin, penicillin, tetracycline, tilmicosin, and trimethoprim-sulfamethoxazole.
PubMed:
Anticlastogenic activity of cacao: inhibitory effect of cacao liquor polyphenols against mitomycin C-induced DNA damage.
PubMed:
Aroma components of cooked tail meat of American lobster (Homarus americanus).
PubMed:
Improved high-performance liquid chromatography method to determine theobromine and caffeine in cocoa and cocoa products.
PubMed:
[Determination of bisphenol A in foods using GC/MS].
PubMed:
Diverse biological activity of polycaphenol.
PubMed:
Determination of conjugated linoleic acid (CLA) concentrations in milk chocolate.
PubMed:
Development of antirotavirus agents in Asia.
PubMed:
Cariostatic activity of cacao mass extract.
PubMed:
Caries inhibitory activity of cacao bean husk extract in in-vitro and animal experiments.
PubMed:
Determination of inulin in foods.
PubMed:
[Antibacterial effects of cacao mass on enterohemorrhagic Escherichia coli O157:H7].
PubMed:
Resistance profile survey of 50 periodontal strains of Actinobacillus actinomyectomcomitans.
PubMed:
Pharmacologic effects of cocoa and rye flour extracts on isolated guinea pig trachea.
PubMed:
Nutritive value of hot water- or cocoa-pod ash solution-treated cocoa bean cake for broiler chicks.
PubMed:
Respiratory function and immunological status in cocoa and flour processing workers.
PubMed:
Comparison of axenic and monoxenic media for isolation of Acanthamoeba.
PubMed:
Helicobacter pylori--in vitro susceptibility to garlic (Allium sativum) extract.
PubMed:
Evaluation of an extended blood culture protocol to isolate fastidious organisms from patients with AIDS.
PubMed:
Nutrient and antinutrient profiles of raw and fermented cocoa beans.
PubMed:
Theobromine toxicity on Sertoli cells and comparison with cocoa extract in male rats.
PubMed:
Agar disk diffusion (Bauer-Kirby) tests with various fastidious and nonfastidious reference (ATCC) strains: comparison of several agar media.
PubMed:
Determination of aspartame and its major decomposition products in foods.
PubMed:
Determination of acesulfam-K in foods.
PubMed:
Effects of long-term laxative treatment on neuropeptides in rat mesenteric vessels and caecum.
PubMed:
Triacetin as food additive in gummy candy and other foodstuffs on the market.
PubMed:
Reproductive toxicity of theobromine and cocoa extract in male rats.
PubMed:
Effect of cacao husk extract on human immunodeficiency virus infection.
PubMed:
Egg yolk emulsion agar, a new medium for the cultivation of Helicobacter pylori.
PubMed:
A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia.
PubMed:
Effects of long-term laxative treatment on rat mesenteric resistance vessel responses in vitro.
PubMed:
Inhibitory effects of aqueous extract of cacao bean husk on collagenase of Bacteroides gingivalis.
PubMed:
[Haemophilus somnus as a cause of bronchopneumonia in calves].
PubMed:
Improved medium for antimicrobial susceptibility testing of Haemophilus influenzae.
PubMed:
Studies on the estrogenic activity of a coffee extract.
PubMed:
Pseudomonas mesophilica infections in humans.
PubMed:
[Acute recurring Quincke edema in allergy to malt extract].
PubMed:
[Effect of the harvest season on the composition of raw and fermented cotyledons of 2 varieties of cacao and shell fractions].
PubMed:
Extraction procedures for oilseeds and related high fat-low moisture products.
PubMed:
[Isolation of the Derivatives from Coca-Powder Fumigated by Ethylene Oxide 1,2-14 C and their Structure Suggested on the Basis of I. R. and Mass-Spectrometry].
PubMed:
[Group separation of ethylene oxide 1,2-14c fumigated coca-powder derivatives and their distribution of radioactivity (author's transl)].
PubMed:
Diets for Rearing the Ambrosia Beetle Xyleborus ferrugineus (Fabricius) in vitro.
PubMed:
Effect on hamster caries by dialysed, detanned or carbon-treated water-extract of cocoa.
PubMed:
[A discussion contribution to spectrophotometric differentiation of cocoa pressed butter and cocoa fat extract].