Identification

Namemethyl cellulose
IUPAC(5R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
CAS Number9004-67-5
FDA UNIIMRJ667KA5E
Molecular FormulaC H4 O.x-Unspecified
MDL NumberMFCD00081763

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices182.1480
JECFA Food AdditiveMethyl Cellulose
GSFA CodexMethyl cellulose (461)
DG SANTE Food Additivesmethyl cellulose
DG SANTE Food Contact Materialsmethyl cellulose
FEMA Number2696
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)9004-67-5 ; CELLULOSE, METHYL
FDA RegulationFDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS

Physical Properties

Appearance white to pale yellow powder (est)
Assay 90.00 to 100.00
Food Chemicals Codex Listed No
Soluble in acetic acid
Insoluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbinding agents

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 275000 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorymultiple purpose GRAS food substances
Recommendation for methyl cellulose usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy0.50000
fruit ices0.50000
gelatins / puddings-
granulated sugar-
gravies-
hard candy0.50000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

binding agents emulsion stabilisers stabilising agents viscosity controlling agents

Natural Occurrence

not found in nature

Synonyms

benecel methylcellulose cellulose methyl ether cellulose methylate methyl cellulose 400 CPS methyl cellulose 4000 CPS methylcellulose TICacel HV powder TICacel LV powder (5R)-2,3,4- trimethoxy-6-(methoxymethyl)-5-[(2S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane PubMed: Investigation of the mechanisms of using metal complexation and cellulose nanofiber/sodium alginate layer-by-layer coating for retaining anthocyanin pigments in thermally processed blueberries in aqueous media. PubMed: Application of foam-mat drying with egg white for carrageenan: drying rate and product quality aspects. PubMed: Robust Ultraviolet-Visible (UV-Vis) Partial Least-Squares (PLS) Models for Tannin Quantification in Red Wine. PubMed: Non-wheat pasta based on pearl millet flour containing barley and whey protein concentrate. PubMed: Optimization of process parameters for foam-mat drying of papaya pulp. PubMed: Impact of dietary fibers [methyl cellulose, chitosan, and pectin] on digestion of lipids under simulated gastrointestinal conditions. PubMed: Cellular trafficking and anticancer activity of Garcinia mangostana extract-encapsulated polymeric nanoparticles. PubMed: Production of low fat french-fries with single and multi-layer hydrocolloid coatings. PubMed: Near-infrared and fourier transform infrared chemometric methods for the quantification of crystalline tacrolimus from sustained-release amorphous solid dispersion. PubMed: Process optimization for the manufacture of lemon based beverage from hydrolyzed whey. PubMed: Hybrid HPMC nanocomposites containing bacterial cellulose nanocrystals and silver nanoparticles. PubMed: Enhanced bioavailability and bioefficacy of an amorphous solid dispersion of curcumin. PubMed: Advances in nanomedicines for malaria treatment. PubMed: Examination of molecular mechanism for the enhanced thermal stability of anthocyanins by metal cations and polysaccharides. PubMed: Nanocomposite PAAm/methyl cellulose/montmorillonite hydrogel: evidence of synergistic effects for the slow release of fertilizers. PubMed: Physico-chemical stability of astaxanthin nanodispersions prepared with polysaccharides as stabilizing agents. PubMed: Physical-mechanical and antimicrobial properties of nanocomposite films with pediocin and ZnO nanoparticles. PubMed: Microstructure and characteristics of high-amylose corn starch-chitosan film as affected by composition. PubMed: Viscous methyl cellulose solution thickens gastric mucosa and increases the number of gland mucous cells in mice. PubMed: Repellency of essential oils to Frankliniella occidentalis (Thysanoptera: Thripidae) as affected by type of oil and polymer release. PubMed: Antimicrobial assays of natural extracts and their inhibitory effect against Listeria innocua and fish spoilage bacteria, after incorporation into biopolymer edible films. PubMed: 2-O-Methyl- and 3,6-di-O-methyl-cellulose from natural cellulose: synthesis and structure characterization. PubMed: Formulation and Evaluation of Cephalexin Extended-release Matrix Tablets Using Hydroxy Propyl Methyl Cellulose as Rate-controlling Polymer. PubMed: Studies on effect of additives on protein profile, microstructure and quality characteristics of pasta. PubMed: Optimization of Rabadi-like fermented milk beverage using pearl millet. PubMed: Evaluation of certain food additives and contaminants. PubMed: Development and quality evaluation of aonla mouth freshner. PubMed: Relationship between red wine grades and phenolics. 1. Tannin and total phenolics concentrations. PubMed: Composite edible films based on hydroxypropyl methylcellulose reinforced with microcrystalline cellulose nanoparticles. PubMed: Factors affecting migration of vanillin from chitosan/methyl cellulose films. PubMed: Kinetics of adsorption of whey proteins and hydroxypropyl-methyl-cellulose mixtures at the air-water interface. PubMed: Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals. PubMed: An investigation of microbial adhesion to natural and synthetic polysaccharide-based films and its relationship with the surface energy components. PubMed: Tannin quantification in red grapes and wine: comparison of polysaccharide- and protein-based tannin precipitation techniques and their ability to model wine astringency. PubMed: Effects of microcrystalline cellulose on functional properties of hydroxy propyl methyl cellulose microcomposite films. PubMed: [Rapid detection of three foodborne pathogenic bacteria by multiplex polymerase chain reaction-capillary electrophoresis with laser induced fluorescence detector]. PubMed: Safety assessment of hydroxypropyl methylcellulose as a food ingredient. PubMed: Effect of SO2 concentration on polyphenol development during red wine micro-oxygenation. PubMed: High throughput analysis of red wine and grape phenolics-adaptation and validation of methyl cellulose precipitable tannin assay and modified Somers color assay to a rapid 96 well plate format. PubMed: Effect of different additives on the persistence and insecticidal activity of native strains of Bacillus thuringiensis. PubMed: The role of fat in flavor perception: effect of partition and viscosity in model emulsions. PubMed: Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice. PubMed: Effectiveness of antimicrobial food packaging materials. PubMed: Antimicrobial and physicochemical properties of chitosan-HPMC-based films. PubMed: Skin hydration effects, film formation time, and physicochemical properties of a moisture mask containing Monostroma nitidium water-soluble mucilage. PubMed: Edible bioactive fatty acid-cellulosic derivative composites used in food-packaging applications. PubMed: Ibuprofen effects on behavioral thermoregulation with microwave radiation in albino rats. PubMed: Persistence of volatile compounds in the breath after their consumption in aqueous solutions. PubMed: Cutaneous toxicity studies with methoxy polyethylene glycol-350 (MPEG-350) in rats and rabbits. PubMed: Relation between parotid saliva flow and composition and the perception of gustatory and trigeminal stimuli in foods. PubMed: Inhibitory effects of gastrin releasing peptide on gastric emptying in rats. PubMed: In vitro/in vivo evaluation of two series of TA-5707F controlled release matrix tablets prepared with hydroxypropyl methyl cellulose derivatives with entero-soluble or gel-formation properties. PubMed: [The mutagenic and modifying properties of new gelatinous substances studied by using the Ames test]. PubMed: Effect of a soluble polysaccharide (carboxy methyl cellulose) on the absorption of minerals from the gastrointestinal tract of broilers. PubMed: Effect of a soluble polysaccharide (carboxy methyl cellulose) on the physico-chemical conditions in the gastrointestinal tract of broilers. PubMed: [Study of the effect of rations containing dietary fiber on the level of total lipids and cholesterol in the blood and liver of the rat during a 6.5-month experiment]. PubMed: [The effect of various methods of thermal treatment on the biological value of minced meat of low caloric value for infants' nutrition]. PubMed: [A new kind of dietetic bread enriched with dietary fiber]. PubMed: Mobilization, redistribution and excretion of hexachlorobenzene following food restriction in rats. PubMed: Involvement of insulin in the acute thermogenic responses to food and nonmetabolizable substances. PubMed: Cultural and nutritional studies of zoopathogenic fungi associated with livestock feeds in Nigeria. PubMed: [Differentiation of natural red wines from white wines blended with oenocyanine (author's transl)].