isomaltulose

6-O-alpha-D- glucopyranosyl-D-fructose 6-O-alpha-dextro- glucopyranosyl-dextro-fructose palatinose (3S,4R,5R)-1,3,4,5- tetrahydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one PubMed: Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice. PubMed: The effect of using isomaltulose (Palatinose™) to modulate the glycaemic properties of breakfast on the cognitive performance of children. PubMed: Synthesis and characterization of isomaltulose-derived oligosaccharides produced by transglucosylation reaction of Leuconostoc mesenteroides dextransucrase. PubMed: Development of synbiotics with inulin, palatinose, alpha-cyclodextrin and probiotic bacteria. PubMed: Comparison of the effects of slowly and rapidly absorbed carbohydrates on postprandial glucose metabolism in type 2 diabetes mellitus patients: a randomized trial. PubMed: Transglycosylations employing recombinant α- and β-galactosidases and novel donor substrates. PubMed: Current studies on sucrose isomerase and biological isomaltulose production using sucrose isomerase. PubMed: Crystallization and preliminary X-ray crystallographic analysis of α-glucosidase HaG from Halomonas sp. strain H11. PubMed: Functional characterization of the sucrose isomerase responsible for trehalulose production in plant-associated Pectobacterium species. PubMed: The structural basis of Erwinia rhapontici isomaltulose synthase. PubMed: The effect of lactose-isomaltulose-containing growing-up milks on cognitive performance of Indonesian children: a cross-over study. PubMed: Is there a specific role for sucrose in sports and exercise performance? PubMed: Simple, fast, and efficient process for producing and purifying trehalulose. PubMed: Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity. PubMed: Potential applications of carbohydrases immobilization in the food industry. PubMed: Enhancing isomaltulose production by recombinant Escherichia coli producing sucrose isomerase: culture medium optimization containing agricultural wastes and cell immobilization. PubMed: Mature-stem expression of a silencing-resistant sucrose isomerase gene drives isomaltulose accumulation to high levels in sugarcane. PubMed: Influence of processing on the volatile profile of strawberry spreads made with isomaltulose. PubMed: The effect of selected synbiotics on microbial composition and short-chain fatty acid production in a model system of the human colon. PubMed: Transcriptional analysis of prebiotic uptake and catabolism by Lactobacillus acidophilus NCFM. PubMed: Combining protein and carbohydrate increases postprandial insulin levels but does not improve glucose response in patients with type 2 diabetes. PubMed: Insight into the role of sugars in bud burst under light in the rose. PubMed: Metabolic effects of replacing sucrose by isomaltulose in subjects with type 2 diabetes: a randomized double-blind trial. PubMed: Immobilization of glucosyltransferase from Erwinia sp. using two different techniques. PubMed: Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinose™) ingestion. PubMed: Reduced glycaemic and insulinaemic responses following trehalose and isomaltulose ingestion: implications for postprandial substrate use in impaired glucose-tolerant subjects. PubMed: Microbial sucrose isomerases: producing organisms, genes and enzymes. PubMed: Mechanism-oriented redesign of an isomaltulose synthase to an isomelezitose synthase by site-directed mutagenesis. PubMed: Exercise dose and insulin sensitivity: relevance for diabetes prevention. PubMed: Isomaltulose improves glycemia and maintains run performance in type 1 diabetes. PubMed: Isomaltulose is actively metabolized in plant cells. PubMed: The effect of high lactose-isomaltulose on cognitive performance of young children. A double blind cross-over design study. PubMed: Field performance of transgenic sugarcane expressing isomaltulose synthase. PubMed: Isomaltulose production via yeast surface display of sucrose isomerase from Enterobacter sp. FMB-1 on Saccharomyces cerevisiae. PubMed: Immobilization of Erwinia sp. D12 Cells in Alginate-Gelatin Matrix and Conversion of Sucrose into Isomaltulose Using Response Surface Methodology. PubMed: Sucrose isomerase and its mutants from Erwinia rhapontici can synthesise α-arbutin. PubMed: GLP-1 secretion in response to oral and luminal palatinose (isomaltulose) in rats. PubMed: A new immune-modulating diet enriched with whey-hydrolyzed peptide, fermented milk, and isomaltulose attenuates gut ischemia-reperfusion injury in mice. PubMed: A combined insulin reduction and carbohydrate feeding strategy 30 min before running best preserves blood glucose concentration after exercise through improved fuel oxidation in type 1 diabetes mellitus. PubMed: Studies on absorption and metabolism of palatinose (isomaltulose) in rats. PubMed: Microbial production of palatinose through extracellular expression of a sucrose isomerase from Enterobacter sp. FMB-1 in Lactococcus lactis MG1363. PubMed: Cloning and characterization of a sucrose isomerase from Erwinia rhapontici NX-5 for isomaltulose hyperproduction. PubMed: Isomaltulose Improves Postexercise Glycemia by Reducing CHO Oxidation in T1DM. PubMed: Transgenic expression of trehalulose synthase results in high concentrations of the sucrose isomer trehalulose in mature stems of field-grown sugarcane. PubMed: Palatinose-blended sugar compared with sucrose: different effects on insulin sensitivity after 12 weeks supplementation in sedentary adults. PubMed: Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose). PubMed: Manipulation of glycemic response with isomaltulose in a milk-based drink does not affect cognitive performance in healthy adults. PubMed: Effect of concentration and substrate flow rate on isomaltulose production from sucrose by Erwinia sp. cells immobilized in calcium-alginate using packed bed reactor. PubMed: Sucrose: A prospering and sustainable organic raw material. PubMed: Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45. PubMed: Safer glycemic control using isomaltulose-based enteral formula: a pilot randomized crossover trial. PubMed: Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use. PubMed: Glucosylation of raffinose via alternansucrase acceptor reactions. PubMed: Molecular cloning and functional characterization of a sucrose isomerase (isomaltulose synthase) gene from Enterobacter sp. FMB-1. PubMed: Slowly digestible carbohydrate sources can be used to attenuate the postprandial glycemic response to the ingestion of diabetes-specific enteral formulas. PubMed: Structural determinants of product specificity of sucrose isomerases. PubMed: Isomaltulose production from sucrose by Protaminobacter rubrum immobilized in calcium alginate. PubMed: Beneficial effects on glucose metabolism of chronic feeding of isomaltulose versus sucrose in rats. PubMed: Isomalt production by cloning, purifying and expressing of the MDH gene from Pseudomonas fluorescens DSM 50106 in different strains of E. coli. PubMed: [Physiological and biochemical properties of the bacterium Erwinia rhapontici, a producer of isomaltulose synthase]. PubMed: Palatinose and oleic acid act together to prevent pancreatic islet disruption in nondiabetic obese Zucker rats. PubMed: Food labeling: health claims; dietary noncariogenic carbohydrate sweeteners and dental caries. Final rule. PubMed: Inhibitory action of palatinose and its hydrogenated derivatives on the hydrolysis of alpha-glucosylsaccharides in the small intestine. PubMed: Isomaltose production by modification of the fructose-binding site on the basis of the predicted structure of sucrose isomerase from "Protaminobacter rubrum". PubMed: Recent progress in the synthesis of carbohydrate-based amphiphilic materials: the examples of sucrose and isomaltulose. PubMed: Molecular and physiological role of the trehalose-hydrolyzing alpha-glucosidase from Thermus thermophilus HB27. PubMed: Role of periplasmic trehalase in uptake of trehalose by the thermophilic bacterium Rhodothermus marinus. PubMed: [Production of fructooligosaccharide syrup from sucrose in combination with palatinose and trehalose]. PubMed: Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats. PubMed: Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. PubMed: A palatinose-based balanced formula improves glucose tolerance, serum free fatty acid levels and body fat composition. PubMed: Inhibitory effect of palatinose on glucose absorption in everted rat gut. PubMed: Exogenous oxidation of isomaltulose is lower than that of sucrose during exercise in men. PubMed: A new colorimetric method for determining the isomerization activity of sucrose isomerase. PubMed: Effects of a novel palatinose based enteral formula (MHN-01) carbohydrate-adjusted fluid diet in improving the metabolism of carbohydrates and lipids in patients with esophageal cancer complicated by diabetes mellitus. PubMed: Doubled sugar content in sugarcane plants modified to produce a sucrose isomer. PubMed: Isomaltulose production using free cells: optimisation of a culture medium containing agricultural wastes and conversion in repeated-batch processes. PubMed: Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men. PubMed: Conversion of sucrose into isomaltulose by Enterobacter sp. FMB1, an isomaltulose-producing microorganism isolated from traditional Korean food. PubMed: Application of response surface methodology to cell immobilization for the production of palatinose. PubMed: Sucrose substitutes and their role in caries prevention. PubMed: Molecular characterization of the alpha-glucosidase activity in Enterobacter sakazakii reveals the presence of a putative gene cluster for palatinose metabolism. PubMed: Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA. PubMed: Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45. PubMed: Characterization of the highly efficient sucrose isomerase from Pantoea dispersa UQ68J and cloning of the sucrose isomerase gene. PubMed: The high-affinity maltose/trehalose ABC transporter in the extremely thermophilic bacterium Thermus thermophilus HB27 also recognizes sucrose and palatinose. PubMed: Klebsiella singaporensis sp. nov., a novel isomaltulose-producing bacterium. PubMed: Comparative effect of repeated ingestion of difructose anhydride III and palatinose on the induction of gastrointestinal symptoms in humans. PubMed: Effect of a novel palatinose-based liquid balanced formula (MHN-01) on glucose and lipid metabolism in male Sprague-Dawley rats after short- and long-term ingestion. PubMed: Characterization of Pantoea dispersa UQ68J: producer of a highly efficient sucrose isomerase for isomaltulose biosynthesis. PubMed: Fermentation of five sucrose isomers by human dental plaque bacteria. PubMed: Enhanced conversion of sucrose to isomaltulose by a mutant of Erwinia rhapontici. PubMed: Production of palatinose using Serratia plymuthica cells immobilized in chitosan. PubMed: The effect of palatinose on mental concentration in humans. PubMed: Straightforward route for anchoring a glucosyl moiety onto nucleophilic species: reaction of amines and alcohols with carboxymethyl 3,4,6-tri-O-acetyl-alpha-D-glucopyranoside 2-O-lactone. PubMed: Substrate induction of isomaltulose synthase in a newly isolated Klebsiella sp. LX3. PubMed: Isomaltulose synthase (PalI) of Klebsiella sp. LX3. Crystal structure and implication of mechanism. PubMed: Distinct sucrose isomerases catalyze trehalulose synthesis in whiteflies, Bemisia argentifolii, and Erwinia rhapontici. PubMed: Structural and functional analysis of a putative gene cluster for palatinose transport on the linear chromosome of Agrobacterium tumefaciens MAFF301001. PubMed: Sugar-regulated expression of a putative hexose transport gene in grape. PubMed: A motif rich in charged residues determines product specificity in isomaltulose synthase. PubMed: Decreased sucrose content triggers starch breakdown and respiration in stored potato tubers (Solanum tuberosum). PubMed: Expression, crystallization and preliminary X-ray analysis of isomaltulose synthase (PalI) from Klebsiella sp. LX3. PubMed: Glycosidation of fructose-containing disaccharides using MCM-41 material as the catalyst. PubMed: 13-Week oral toxicity study with isomaltulose (Palatinose) in rats. PubMed: Isomaltulose (Palatinose): a review of biological and toxicological studies. PubMed: Potato tubers as bioreactors for palatinose production. PubMed: Isomaltulose synthase from Klebsiella sp. strain LX3: gene cloning and characterization and engineering of thermostability. PubMed: Metabolizable and non-metabolizable sugars activate different signal transduction pathways in tomato. PubMed: High-level production of the non-cariogenic sucrose isomer palatinose in transgenic tobacco plants strongly impairs development. PubMed: Phosphorylation and metabolism of sucrose and its five linkage-isomeric alpha-D-glucosyl-D-fructoses by Klebsiella pneumoniae. PubMed: The sucrose analog palatinose leads to a stimulation of sucrose degradation and starch synthesis when supplied to discs of growing potato tubers. PubMed: Responses of the ant Lasius niger to various compounds perceived as sweet in humans: a structure-activity relationship study. PubMed: Cloning and characterization of the gene cluster for palatinose metabolism from the phytopathogenic bacterium Erwinia rhapontici. PubMed: Assessment of acid production by various human oral micro-organisms when palatinose or leucrose is utilized. PubMed: Di- and oligosaccharide substrate specificities and subsite binding energies of pig intestinal glucoamylase-maltase. PubMed: Effects of frequent mouthrinses with palatinose and xylitol on dental plaque. PubMed: Bacillus thermoamyloliquefaciens KP1071 alpha-glucosidase II is a thermostable M(r) 540,000 homohexameric alpha-glucosidase with both exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. PubMed: Embryotoxicity/teratogenicity study with isomaltulose (Palatinose) in rats. PubMed: The effects of isomaltulose, isomalt, and isomaltulose-based oligomers on mineral absorption and retention. PubMed: Urinary excretion by dogs of intravenously administered simple sugars. PubMed: The effects of isomaltulose-based oligomers feeding and calcium deficiency on mineral retention in rats. PubMed: Industrial application of immobilized biocatalysts in Japan. PubMed: Transglucosylation with 6'-chloro-6'-deoxysucrose and immobilized isomaltulose-producing microorganisms using 2,2-dimethyl-1,3-dioxolane-4-methanol and its related compounds as acceptors. Steric and chemical requirement of the glucosyl acceptor. PubMed: Characterization of alpha-glucosyltransferase from Pseudomonas mesoacidophila MX-45. PubMed: Downstream processing of sucrose 6-glucosylmutase and production of isomaltulose, a non-cariogenic, low-caloric sweetener. PubMed: Synthesis of dispirodioxanyl pseudo-oligosaccharides by selective protonic activation of isomeric glycosylfructoses in anhydrous hydrogen fluoride. PubMed: Investigation of sucrose synthase from rice for the synthesis of various nucleotide sugars and saccharides. PubMed: Selective protonic activation of isomeric glycosylfructoses with pyridinium poly(hydrogen fluoride) and synthesis of spirodioxanyl oligosaccharides. PubMed: Trehalulose does not induce dental caries in rats infected with mutans streptococci. PubMed: First purification and characterization of a sucrase-isomaltase from goose kidney microvillous membrane. PubMed: Plaque formation of dietary isomaltulose in humans. PubMed: Evaluation of a model for short-term clinical testing of cariogenicity. PubMed: Usefulness of palatinose as a caloric sweetener for diabetic patients. PubMed: Isomaltulose "palatinose". An anticariogenic substitute for glucose. PubMed: Hydrolysis of alpha-D-glucopyranosyl-1,6-sorbitol and alpha-D-glucopyranosyl-1,6-mannitol by rat intestinal disaccharidases. PubMed: [Sugar substitutes--new substances]. PubMed: New experiments on Palatinose (Isomaltulose) as a sugar substitute. PubMed: [Effect of candy containing palatinose on human dental plaque formation]. PubMed: [A stepwise method of evaluating sugar substitutes--a preliminary study using enzymes. 2. Beta-fructosidase from yeast]. PubMed: Effects of parenteral palatinose on glucose metabolism in normal and streptozotocin diabetic rats. PubMed: Palatinose as a potential parenteral nutrient: its metabolic effects and fate after oral and intravenous administration to dogs. PubMed: Changes in blood glucose and insulin after an oral palatinose administration in normal subjects. PubMed: [New sucrose substitutes]. PubMed: Isomaltulose production using immobilized cells. PubMed: Microbiological aspects of some caloric sugar substitutes. PubMed: New trends on sweeteners in Japan. PubMed: [Non-cariogenicity of palatinose]. PubMed: [Caries-inducing activity of Palatinose syrup]. PubMed: Cariogenicity of isomaltulose (palatinose), sucrose and mixture of these sugars in rats infected with Streptococcus mutans E-49. PubMed: Palatinose--a sucrose substitute. Pilot studies. PubMed: The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici. PubMed: [Effect of sugar substitutes on the growth and acid production of 2 types of acidogenic bacteria of the oral cavity]. PubMed: Virulence factors of Streptococcus mutans and dental caries prevention. PubMed: Effect of frequent rinses with isomaltulose (Palatinose) solution on acid production in human dental plaque. PubMed: [Oligosaccharides produced by Streptococcus mutans glucosyltransferase from sucrose with isomaltulose]. PubMed: Cariostatic effect of palatinose on experimental dental caries in rats. PubMed: [Dental caries and palatinose, a structural isomer of sucrose]. PubMed: Effect of isomaltulose on acid production and insoluble glucan synthesis by Streptococcus mutans. PubMed: Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats. PubMed: Acid production from isomaltulose, sucrose, sorbitol, and xylitol in suspensions of human dental plaque. PubMed: Carbohydrate transformations by immobilized cells. PubMed: [Inhibitory mechanism of isomaltulose for insoluble glucan synthesis by Streptococcus mutans (author's transl)]. PubMed: [Analytical characterization of palatinit (author's transl)]. PubMed: [Formation of acids by cariogenically important streptococci from sugars and sugar alcohols with special reference to isomaltitol and isomaltulose]. PubMed: Human intestinal disaccharidases and hereditary disaccharide intolerance. The hydrolysis of sucrose, isomaltose, palatinose (isomaltulose), and a 1,6-alpha-oligosaccharide (isomalto-oligosaccharide) preparation.