No sensory data available
Potential Uses
None Found
Natural Occurrence
tea anther
tea cotyledon
tea leaf
tea seed
tea shoot
tea stem
Synonyms
(2S)-2-2S)-2-
amino-4-(N-ethylcarbamoyl)butanoic acid
(2S)-2-
amino-5-(ethylamino)-5-oxopentanoic acid
(S)-2-
amino-5-(ethylamino)-5-oxopentanoic acid
N-
ethyl-L-glutamine
N-
ethyl-laevo-glutamine
L-
glutamine, N-ethyl-
suntheanine
L-
theanine
PubMed:
Add-on Pregnenolone with L-Theanine to Antipsychotic Therapy Relieves Negative and Anxiety Symptoms of Schizophrenia: An 8-week, randomized, double-blind, placebo-controlled trial.
J-Stage:
The Involvement of L-Type Amino Acid Transporters in Theanine Transport
PubMed:
L-Theanin, Unique Aminoacid of Tea, and Its Metabolism, Health Effects, Safety.
PubMed:
Protective Effect of L-Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway.
PubMed:
Quantification of total polyphenols, catechin, caffeine, L-theanine, determination of antioxidant activity and effect on antileishmanial drugs of ethiopian tea leaves extracts.
PubMed:
Fast Dissolving/Disintegrating Dosage Forms: Growth from Immediate Release to Sustained Release and Traditional Medicines.
PubMed:
Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration?
PubMed:
Epigallocatechin-3-gallate inhibits VCAM-1 expression and apoptosis induction associated with LC3 expressions in TNFα-stimulated human endothelial cells.
PubMed:
Effect of l-theanine on glutamatergic function in patients with schizophrenia.
PubMed:
An overview of biological production of L-theanine.
PubMed:
l-Theanine prevents carbon tetrachloride-induced liver fibrosis via inhibition of nuclear factor κB and down-regulation of transforming growth factor β and connective tissue growth factor.
PubMed:
A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood.
PubMed:
In Search of a Safe Natural Sleep Aid.
PubMed:
Tea (Camellia Sinensis (L.)): a Putative Anticancer Agent in Bladder Carcinoma?
PubMed:
Tea (Camellia sinensis (L.)): a putative anticancer agent in bladder carcinoma?
PubMed:
Investigational drugs for anxiety in patients with schizophrenia.
PubMed:
Acute effects of dietary constituents on motor skill and cognitive performance in athletes.
PubMed:
L-theanine synthesis using γ-glutamyl transpeptidase from Bacillus licheniformis ER-15.
PubMed:
Effects of L-theanine on posttraumatic stress disorder induced changes in rat brain gene expression.
PubMed:
Inhibition of lung tumor growth by targeting EGFR/VEGFR-Akt/NF-κB pathways with novel theanine derivatives.
PubMed:
L-Theanine healed NSAID-induced gastric ulcer by modulating pro/antioxidant balance in gastric ulcer margin.
PubMed:
Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis.
PubMed:
Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease.
PubMed:
Protective effect of L-Theanine against aluminium induced neurotoxicity in cerebral cortex, hippocampus and cerebellum of rat brain - histopathological, and biochemical approach.
PubMed:
L-Theanine elicits umami taste via the T1R1 + T1R3 umami taste receptor.
PubMed:
Identifying key non-volatile compounds in ready-to-drink green tea and their impact on taste profile.
PubMed:
Effect of L-theanine on sensorimotor gating in healthy human subjects.
PubMed:
Neuroprotective activity of L-theanine on 3-nitropropionic acid-induced neurotoxicity in rat striatum.
PubMed:
L-theanine (suntheanin): effects of L-theanine, an amino acid derived from Camellia sinensis (green tea), on stress response parameters.
PubMed:
Physiological effects of L-theanine on Drosophila melanogaster.
PubMed:
To sleep or not to sleep: a systematic review of the literature of pharmacological treatments of insomnia in children and adolescents with attention-deficit/hyperactivity disorder.
PubMed:
Suppression of proliferation and migration in highly-metastatic lung cancer cells as well as tumor growth by a new synthesized compound TBrC and its molecular mechanisms of action.
PubMed:
Electron paramagnetic resonance studies of gamma-irradiated DL-alanine ethyl ester hydrochloride, L-theanine and L-glutamic acid dimethyl ester hydrochloride.
PubMed:
Effect of electrolyzed reduced water on chiral theanine and polyphenols in tea.
PubMed:
Protective effect of l-theanine on chronic restraint stress-induced cognitive impairments in mice.
PubMed:
L-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures.
PubMed:
L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway.
PubMed:
The involvement of L-type amino acid transporters in theanine transport.
PubMed:
[Mechanisms of cerebral protection from ischemia by tea constituents].
PubMed:
Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses.
PubMed:
L-theanine administration results in neuroprotection and prevents glutamate receptor agonist-mediated injury in the rat model of cerebral ischemia-reperfusion.
PubMed:
Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea.
PubMed:
l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice.
PubMed:
Rapid and selective quantification of L-theanine in ready-to-drink teas from Chinese market using SPE and UPLC-UV.
PubMed:
L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation.
PubMed:
Protective effect of L-theanine on carbon tetrachloride-induced acute liver injury in mice.
PubMed:
L-Theanine extends lifespan of adult Caenorhabditis elegans.
PubMed:
Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
PubMed:
L-theanine partially counteracts caffeine-induced sleep disturbances in rats.
PubMed:
[Raman spectral analysis of theanine].
PubMed:
Tea and cognitive health in late life: current evidence and future directions.
PubMed:
The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial.
PubMed:
Nerve and behavioral responses of mice to various umami substances.
PubMed:
l-Theanine prevents alcoholic liver injury through enhancing the antioxidant capability of hepatocytes.
PubMed:
Behavioral and molecular evidence for psychotropic effects in L-theanine.
PubMed:
Optimum conditions for the water extraction of L-theanine from green tea.
PubMed:
L-Theanine: properties, synthesis and isolation from tea.
PubMed:
Serum levels of brain-derived neurotrophic factor and cortisol to sulfate of dehydroepiandrosterone molar ratio associated with clinical response to L-theanine as augmentation of antipsychotic therapy in schizophrenia and schizoaffective disorder patients.
PubMed:
Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice.
PubMed:
Production of bioactive γ-glutamyl transpeptidase in Escherichia coli using SUMO fusion partner and application of the recombinant enzyme to L-theanine synthesis.
PubMed:
A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study.
PubMed:
L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
PubMed:
A randomized targeted amino acid therapy with behaviourally at-risk adopted children.
PubMed:
The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness.
PubMed:
L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway.
PubMed:
Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat.
PubMed:
L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness.
PubMed:
Effects of (L)-cystine and (L)-theanine supplementation on the common cold: a randomized, double-blind, and placebo-controlled trial.
PubMed:
Neuroprotection by radical avoidance: search for suitable agents.
PubMed:
Combined administration of (L)-cystine and (L)-theanine enhances immune functions and protects against influenza virus infection in aged mice.
PubMed:
l-Theanine, an amino acid in green tea, attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity: reduction in oxidative damage and inactivation of ERK/p38 kinase and NF-kappaB pathways.
PubMed:
Impact of two types of Internet-based information on medical students' performance in an Objective Structured Clinical Exam (OSCE).
PubMed:
Co-administration of l-cystine and l-theanine enhances efficacy of influenza vaccination in elderly persons: nutritional status-dependent immunogenicity.
PubMed:
Tea and health: preventive and therapeutic usefulness in the elderly?
PubMed:
L-theanine elicits an umami taste with inosine 5'-monophosphate.
PubMed:
The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task.
PubMed:
The combined effects of L-theanine and caffeine on cognitive performance and mood.
PubMed:
L-theanine and caffeine in combination affect human cognition as evidenced by oscillatory alpha-band activity and attention task performance.
PubMed:
L-theanine, a natural constituent in tea, and its effect on mental state.
PubMed:
Immobilization of Escherichia coli novablue gamma-glutamyltranspeptidase in Ca-alginate-kappa-carrageenan beads.
PubMed:
Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death.
PubMed:
Effect of green tea and (-)-epigallocatechin gallate on ethanol-induced toxicity in HepG2 cells.
PubMed:
L-theanine intervention enhances human gammadeltaT lymphocyte function.
PubMed:
Psychological effects of dietary components of tea: caffeine and L-theanine.
PubMed:
Enhancement of antigen-specific immunoglobulin G production in mice by co-administration of L-cystine and L-theanine.
PubMed:
[Separation and quantification of theanine enantiomers using high performance liquid chromatography coupled with chiral derivatization].
PubMed:
Bioactive food components that enhance gammadelta T cell function may play a role in cancer prevention.
PubMed:
Source density analysis of the human EEG after ingestion of a drink containing decaffeinated extract of green tea enriched with L-theanine and theogallin.
PubMed:
The effects of L-theanine, caffeine and their combination on cognition and mood.
PubMed:
Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: II. Characterization in the freely moving rat by means of quantitative field potential analysis.
PubMed:
Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: I. electrophysiological characterization in the rat hippocampus in-vitro.
PubMed:
Effect of valerian extract preparation (BIM) on the sleep-wake cycle in rats.
PubMed:
The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent.
PubMed:
Expression optimization and biochemical characterization of a recombinant gamma-glutamyltranspeptidase from Escherichia coli novablue.
PubMed:
Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.
PubMed:
L-Theanine reduces psychological and physiological stress responses.
PubMed:
A 13-week dietary toxicity and toxicokinetic study with l-theanine in rats.
PubMed:
Molecular and sensory studies on the umami taste of Japanese green tea.
PubMed:
L-theanine . Monograph.
PubMed:
Pharmacokinetics of theanine enantiomers in rats.
PubMed:
The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans.
PubMed:
Analysis of derivatized and underivatized theanine enantiomers by high-performance liquid chromatography/atmospheric pressure ionization-mass spectrometry.
PubMed:
Antigens in tea-beverage prime human Vgamma 2Vdelta 2 T cells in vitro and in vivo for memory and nonmemory antibacterial cytokine responses.