3-nonanone
ethyl hexyl ketone
Identification
| Name | 3-nonanone |
| IUPAC | nonan-3-one |
| CAS Number | 925-78-0 |
| EINECS | 213-125-2 |
| FDA UNII | 00C380UHNL |
| Molecular Formula | C9 H18 O |
| Molecular Weight | 142.24166000 |
| MDL Number | MFCD00009541 |
| Nikkaji Number | J121.213C |
| Beilstein | 1700447 |
| CoE Number | 11160 |
| XlogP3 | 2.80 (est) |
Regulatory
| JECFA Food Flavoring | 294 3-nonanone |
| DG SANTE Food Flavourings | 07.113 nonan-3-one |
| FEMA Number | 3440 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 925-78-0 ; 3-NONANONE |
Physical Properties
| Appearance | colorless clear liquid (est) |
| Assay | 97.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 0.81700 to 0.82300 @ 25.00 °C. |
| Pounds per Gallon - (est). | 6.798 to 6.848 |
| Refractive Index | 1.41500 to 1.42300 @ 20.00 °C. |
| Melting Point | -80.00 °C. @ 760.00 mm Hg |
| Boiling Point | 187.00 to 188.00 °C. @ 760.00 mm Hg, 80.00 °C. @ 20.00 mm Hg |
| Acid Value | 2.00 max. KOH/g |
| Vapor Pressure | 0.551000 mmHg @ 25.00 °C. (est) |
| Vapor Density | >1 ( Air = 1 ) |
| Flash Point | 154.00 °F. TCC ( 67.78 °C. ) |
| logP (o/w) | 3.015 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | perfuming agents |
Organoleptic Properties
| Odor Strength | medium , |
| Substantivity | 8 hour(s) at 100.00 % |
| Odor Description |
at 10.00 % in dipropylene glycol. A grassy, herbal, green, fruity odor Fruity, Leafy, Herbaceous, Pungent
|
| Odor sample from | Bedoukian Research, Inc. |
| Taste Description |
green spicy herbal grassy cilantro leafy green
|
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for 3-nonanone usage levels up to | 2.0000 % in the fragrance concentrate. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.12 (μg/capita/day) |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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Potential Uses
Natural Occurrence
Synonyms
ethyl hexyl ketone
ethyl N-hexyl ketone
ethylhexyl ketone
N-
hexyl ethyl ketone
ketone, ethyl hexyl
nonan-3-one
3-
nonanone
3-
nonanone natural
PubMed:
Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose.
PubMed:
7,7-[Ethane-1,2-diylbis(oxy)]-2-[hydroxy(phenyl)methyl]bicyclo[3.3.1]nonan-3-one.
PubMed:
Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose.
PubMed:
Volatile constituents of commercial imported and domestic black-ripe table olives (Olea europaea).
PubMed:
Cu/Nitroxyl Catalyzed Aerobic Oxidation of Primary Amines into Nitriles at Room Temperature.
PubMed:
Odour-active compounds in guava (Psidium guajava L. cv. Red Suprema).
PubMed:
Determination of the relative configuration of tropinone and granatanone aldols by using TBDMS ethers.
PubMed:
(1S*,5R*)-9-Phenyl-9-aza-bicyclo-[3.3.1]nonan-3-one.
PubMed:
Intramolecular [2+2] photocycloaddition reactions as an entry to the 2-oxatricyclo[4.2.1.0(4,9)]nonan-3-one skeleton of lactiflorin.
PubMed:
(1RS,2SR,5SR)-9-Benzyl-2-[(1RS)-1-hy-droxy-benz-yl]-9-aza-bicyclo-[3.3.1]nonan-3-one from synchrotron data.
PubMed:
Comparison of volatile components in Chinese traditional pickled peppers using HS-SPME-GC-MS, GC-O and multivariate analysis.
PubMed:
Isolation and characterization of 4-tert-butylphenol-utilizing Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment.
PubMed:
(-)-(1S,5R)-2-Oxabicyclo-[3.3.1]nonan-3-one.
PubMed:
Widespread occurrence of estrogenic UV-filters in aquatic ecosystems in Switzerland.
PubMed:
Biparental endowment of endogenous defensive alkaloids in Epilachna paenulata.
PubMed:
Simultaneous trace determination of nine organic UV-absorbing compounds (UV filters) in environmental samples.
PubMed:
Templation of the excited-state chemistry of alpha-(n-alkyl) dibenzyl ketones: how guest packing within a nanoscale supramolecular capsule influences photochemistry.
PubMed:
Reactions of cyclopropanone acetals with alkyl azides: carbonyl addition versus ring-opening pathways.
PubMed:
A comparison of ionic liquids to molecular organic solvents as additives for chiral separations in micellar electrokinetic chromatography.
PubMed:
Iridoids from Crescentia alata.
PubMed:
Optical spectra of protected diamine 10-bond-bridged intervalence radical cations related to N,N,N'N'-tetraalkylbenzidine.
PubMed:
Comparative studies on enzyme preparations and role of cell components for (R)-phenylacetylcarbinol production in a two-phase biotransformation.
PubMed:
Chemical boundaries for detection of eye irritation in humans from homologous vapors.
PubMed:
Ergosterol elicits oxidative burst in tobacco cells via phospholipase A2 and protein kinase C signal pathway.
PubMed:
Synthesis of (4R,6S,7R)-7-hydroxy-4,6-dimethyl-3-nonanone and (3R,5S,6R)- 6-hydroxy-3,5-dimethyl-2-octanone, the pheromone components of the bostrychid beetle, Dinoderus bifoveolatus.
PubMed:
Endothelium-dependent hyperpolarization to acetylcholine in carotid artery of guinea pig: role of lipoxygenase.
PubMed:
Convenient Synthesis of N-Benzyl-1,4-dihydropyridines, Cyclohexenones, and Bicyclo[3.3.1]nonan-3-one Derivatives from 1-Aza-1,3-butadienes.
PubMed:
Hesperophylax occidentalis (Trichoptera: Limnephilidae): Electroantennogram structure-activity study of sex pheromone component 6-methylnonan-3-one.
PubMed:
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of 2-hydroxy-3-nonyl derivatives of azoles.
PubMed:
New C26 delta-lactones from the Dufour's gland of the urticating ant Tetramorium aculeatum.
PubMed:
[Synthesis of radiosensitizers. Part VII. Synthesis of 3-bromo-4-chlorophenacyl alkylxanthates].
PubMed:
Antidopaminergic effects of the stereoisomers of N-[(1-alkyl-2- pyrrolidinyl)methyl]-5-sulfamoylbenzamides and -2,3-dihydrobenzofuran-7-carboxamides.
PubMed:
Stereocontrolled syntheses for the six diastereomeric 1,2-dihydroxy-4,5-diaminocyclohexanes: PtII complexes and P-388 antitumor properties.
PubMed:
Anticonvulsant evaluation of some 3-oxo and 3-thiosemicarbazono analogues of 1-aryl-1-ethylthio-nonanes and related compounds.
PubMed:
Reinvestigation of anhydroserricornin, (2S,3S)-2,6-diethyl-3,5-dimethyl-3,4-dihydro-2H-pyran, as a sex pheromone component for male cigarette beetle.
PubMed:
Inhibitory action of (4S,6S,7R)-isomer to pheromonal activity of serricornin, (4S,6S,7S)-7-Hydroxy-4,6-dimethyl-3-nonanone.
PubMed:
Synthesis of no-carrier-added N-([18F]fluoroalkyl)spiperone derivatives.
PubMed:
Plasma protein changes in rats treated with hypolipidaemic drugs and with phthalate esters.
PubMed:
Experimental study on the enhancement of the neurotoxicity of methyl n-butyl ketone by non-neurotoxic aliphatic monoketones.