tricalcium silicate

calcium silicate (Ca3SiO5)

CAS: 12168-85-3 Ca3 O5 Si MW: 228.31530000

Identification

Nametricalcium silicate
CAS Number12168-85-3
EINECS235-336-9
FDA UNII404G39282C
Molecular FormulaCa3 O5 Si
Molecular Weight228.31530000

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices182.2906

Physical Properties

Appearance colorless crystalline powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w) 0.651 (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood additive
Recommendation for tricalcium silicate usage levels up tonot for fragrance use.
Recommendation for tricalcium silicate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

calcium oxide silicate (Ca3O(SiO4)) calcium silicate (Ca3SiO5) calcium silicon oxide (Ca3SiO5) dicalcium oxocalcium silicate PubMed: Primate pulpal healing after exposure and TheraCal application. PubMed: Radiopacifier Particle Size Impacts the Physical Properties of Tricalcium Silicate-based Cements. PubMed: Interfacial characteristics of Biodentine and MTA with dentine in simulated body fluid. PubMed: Comparison of Quick-Set and Mineral Trioxide Aggregate Root-end Fillings for the Regeneration of Apical Tissues in Dogs. PubMed: Influence of composition on setting kinetics of new injectable and/or fast setting tricalcium silicate cements. PubMed: In situ assessment of the setting of tricalcium silicate-based sealers using a dentin pressure model. PubMed: Tricalcium silicate cements with resins and alternative radiopacifiers. PubMed: Ion release, porosity, solubility, and bioactivity of MTA Plus tricalcium silicate. PubMed: Comparative evaluation of shear bond strength and microleakage of tricalcium silicate-based restorative material and radioopaque posterior glass ionomer restorative cement in primary and permanent teeth: an in vitro study. PubMed: Mineral trioxide aggregate (MTA)-like materials: an update review. PubMed: Investigation of a novel mechanically mixed mineral trioxide aggregate (MM-MTA(™) ). PubMed: Hydration of Biodentine, Theracal LC, and a prototype tricalcium silicate-based dentin replacement material after pulp capping in entire tooth cultures. PubMed: Capping a pulpotomy with calcium aluminosilicate cement: comparison to mineral trioxide aggregates. PubMed: Comparison of pulpal responses to pulpotomy and pulp capping with biodentine and mineral trioxide aggregate in dogs. PubMed: Evaluation of shear bond strength of two resin-based composites and glass ionomer cement to pure tricalcium silicate-based cement (Biodentine®). PubMed: Zinc incorporation improves biological activity of beta-tricalcium silicate resin-based cement. PubMed: Sealers and warm gutta-percha obturation techniques. PubMed: Characterization of un-hydrated and hydrated BioAggregate™ and MTA Angelus™ PubMed: Zoledronate and ion-releasing resins impair dentin collagen degradation. PubMed: X-ray diffraction analysis of MTA-Plus, MTA-Angelus and DiaRoot BioAggregate. PubMed: Cytocompatibility and antibacterial properties of capping materials. PubMed: Biodentine induces human dental pulp stem cell differentiation through mitogen-activated protein kinase and calcium-/calmodulin-dependent protein kinase II pathways. PubMed: Frequently asked questions in direct pulp capping of permanent teeth. PubMed: Effect of saliva and blood contamination on the bi-axial flexural strength and setting time of two calcium-silicate based cements: Portland cement and biodentine. PubMed: Influence of QMix irrigant on the micropush-out bond strength of biodentine and white mineral trioxide aggregate. PubMed: Acidic pH weakens the microhardness and microstructure of three tricalcium silicate materials. PubMed: A force field for tricalcium aluminate to characterize surface properties, initial hydration, and organically modified interfaces in atomic resolution. PubMed: Hydration characteristics of Biodentine and Theracal used as pulp capping materials. PubMed: Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials. PubMed: Effects of tricalcium silicate cements on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro. PubMed: Investigation of chemical changes in sealers during application of the warm vertical compaction technique. PubMed: New treatment option for an incomplete vertical root fracture--a preliminary case report. PubMed: Biodentine™ material characteristics and clinical applications: a review of the literature. PubMed: Application of hydration reaction on the removal of recalcitrant contaminants in leachate after biological treatment. PubMed: In vitro biocompatibility of a dentine substitute cement on human MG63 osteoblasts cells: Biodentine™ versus MTA(®). PubMed: Effect of Biodentine™ on the proliferation, migration and adhesion of human dental pulp stem cells. PubMed: Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report. PubMed: Comparison of the radiopacities of different root-end filling and repair materials. PubMed: Shear bond strengths of different adhesive systems to biodentine. PubMed: Trace metal contents of three tricalcium silicate materials: MTA Angelus, Micro Mega MTA and Bioaggregate. PubMed: Porosity and root dentine to material interface assessment of calcium silicate-based root-end filling materials. PubMed: Physical properties of 5 root canal sealers. PubMed: [Comparative study of antimicrobial activity of "Biodentin" and "Rootdent" cements and "Futurabond NR" adhesive]. PubMed: In vitro osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement. PubMed: Role of the extracellular signal-regulated kinase 1/2 pathway in driving tricalcium silicate-induced proliferation and biomineralization of human dental pulp cells in vitro. PubMed: In vitro cytotoxicity of white MTA, MTA Fillapex® and Portland cement on human periodontal ligament fibroblasts. PubMed: Investigation of Biodentine as dentine replacement material. PubMed: Response of human dental pulp capped with biodentine and mineral trioxide aggregate. PubMed: Biointeractivity-related versus chemi/physisorption-related apatite precursor-forming ability of current root end filling materials. PubMed: Investigation of the hydration and bioactivity of radiopacified tricalcium silicate cement, Biodentine and MTA Angelus. PubMed: Influence of light and oxygen on the color stability of five calcium silicate-based materials. PubMed: In vitro cytotoxicity evaluation of a novel root repair material. PubMed: New options for restoring a deep carious lesion. PubMed: Spheroid model study comparing the biocompatibility of Biodentine and MTA. PubMed: Pulp capping materials-is there anything better than Dycal? PubMed: Chemical characteristics of mineral trioxide aggregate and its hydration reaction. PubMed: Effect of various endodontic irrigants on the push-out bond strength of biodentine and conventional root perforation repair materials. PubMed: Influence of acrylic superplasticizer and cellulose-ether on the kinetics of tricalcium silicate hydration reaction. PubMed: Variation of the ultrasonic response of a dental implant embedded in tricalcium silicate-based cement under cyclic loading. PubMed: A biocompatible and bioactive replacement for dentine: is this a reality? The properties and uses of a novel calcium-based cement. PubMed: Clinical case reports using a novel calcium-based cement. PubMed: Characterization of set Intermediate Restorative Material, Biodentine, Bioaggregate and a prototype calcium silicate cement for use as root-end filling materials. PubMed: Biodentine used as a pulp-capping agent in primary pig teeth. PubMed: Mineral trioxide aggregate with anti-washout gel - properties and microstructure. PubMed: Investigation of the physical properties of tricalcium silicate cement-based root-end filling materials. PubMed: Vital pulp therapy with pulp capping. PubMed: New nanostructural biomaterials based on active silicate systems and hydroxyapatite: characterization and genotoxicity in human peripheral blood lymphocytes. PubMed: In vitro studies of calcium phosphate silicate bone cements. PubMed: Effect of tricalcium silicate (Ca(3)SiO(5)) bioactive material on reducing enamel demineralization: an in vitro pH-cycling study. PubMed: Effect of a calcium-silicate-based restorative cement on pulp repair. PubMed: Biodentine induces immortalized murine pulp cell differentiation into odontoblast-like cells and stimulates biomineralization. PubMed: A study on the sealing ability and antibacterial activity of Ca3SiO5/CaCl2 composite cement for dental applications. PubMed: Reactions and surface interactions of saccharides in cement slurries. PubMed: Proactive intervention dentistry: a model for oral care through life. PubMed: In vitro microleakage of Biodentine as a dentin substitute compared to Fuji II LC in cervical lining restorations. PubMed: Effects of calcium silicate-based materials on collagen matrix integrity of mineralized dentin. PubMed: Antibacterial activity of a new mineral trioxide aggregate-based root canal sealer. PubMed: Clinical evaluation of the performance and safety of a new dentine substitute, Biodentine, in the restoration of posterior teeth - a prospective study. PubMed: The microstructure and surface morphology of radiopaque tricalcium silicate cement exposed to different curing conditions. PubMed: Characterization and analyses of acid-extractable and leached trace elements in dental cements. PubMed: Biodentine(TM) induces TGF-β1 release from human pulp cells and early dental pulp mineralization. PubMed: The effect of curing conditions on the physical properties of tricalcium silicate cement for use as a dental biomaterial. PubMed: Bioactive composite bone cement based on α-tricalcium phosphate/tricalcium silicate. PubMed: Hydration kinetics of tricalcium silicate by calorimetric methods. PubMed: Antibacterial activity of two MTA-based root canal sealers. PubMed: Effect of tricalcium silicate on the proliferation and odontogenic differentiation of human dental pulp cells. PubMed: Biomimetic calcium-silicate cements support differentiation of human orofacial mesenchymal stem cells. PubMed: Tricalcium silicate induced mineralization for occlusion of dentinal tubules. PubMed: Characterization and hydration kinetics of tricalcium silicate cement for use as a dental biomaterial. PubMed: Anti-washout carboxymethyl chitosan modified tricalcium silicate bone cement: preparation, mechanical properties and in vitro bioactivity. PubMed: Nanostructure of calcium silicate hydrates in cements. PubMed: Effect of tricalcium aluminate on the properties of tricalcium silicate-tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility. PubMed: Biomimetic calcium-silicate cements aged in simulated body solutions. Osteoblast response and analyses of apatite coating. PubMed: Apatite formation on bioactive calcium-silicate cements for dentistry affects surface topography and human marrow stromal cells proliferation. PubMed: The apatite formation ability of CaF2 doping tricalcium silicates in simulated body fluid. PubMed: Phase composition of ProRoot mineral trioxide aggregate by X-ray powder diffraction. PubMed: [Study of spectra characteristics of Ca3SiO5 : Eu2+ phosphor]. PubMed: Sealing ability of grar MTA AngelusTM, CPM TM and MBPc used as apical plugs. PubMed: Novel bioactive composite bone cements based on the beta-tricalcium phosphate-monocalcium phosphate monohydrate composite cement system. PubMed: Characterization and chemical activity of Portland cement and two experimental cements with potential for use in dentistry. PubMed: Effect of sodium carbonate solution on self-setting properties of tricalcium silicate bone cement. PubMed: Adsorption of polyelectrolytes and its influence on the rheology, zeta potential, and microstructure of various cement and hydrate phases. PubMed: Induction of specific cell responses to a Ca(3)SiO(5)-based posterior restorative material. PubMed: Immobilisation of heavy metal in cement-based solidification/stabilisation: a review. PubMed: Study on physicochemical properties and in vitro bioactivity of tricalcium silicate-calcium carbonate composite bone cement. PubMed: Characterization of carbonated tricalcium silicate and its sorption capacity for heavy metals: a micron-scale composite adsorbent of active silicate gel and calcite. PubMed: Nano-pH sensor for the study of reactive materials. PubMed: Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4.1/2H2O composite cement. PubMed: The constitution, physical properties and biocompatibility of modified accelerated cement. PubMed: Self-setting properties and in vitro bioactivity of calcium sulfate hemihydrate-tricalcium silicate composite bone cements. PubMed: Hydration mechanisms of mineral trioxide aggregate. PubMed: Characterisation of products of tricalcium silicate hydration in the presence of heavy metals. PubMed: Characterization of Ca3SiO5/CaCl2 composite cement for dental application. PubMed: Novel tricalcium silicate/monocalcium phosphate monohydrate composite bone cement. PubMed: In vitro bioactivity of novel tricalcium silicate ceramics. PubMed: Near-infrared spectroscopy investigation of the water confined in tricalcium silicate pastes. PubMed: Hydration process of cement in the presence of a cellulosic additive. A calorimetric investigation. PubMed: Hydration of tricalcium and dicalcium silicate mixtures studied using quasielastic neutron scattering. PubMed: Investigation into the stabilization/solidification performance of Portland cement through cement clinker phases. PubMed: X-ray diffraction analysis of mineral trioxide aggregate and Portland cement. PubMed: Formation of the C-S-H Layer during early hydration of tricalcium silicate grains with different sizes. PubMed: Characterization of Portland cement for use as a dental restorative material. PubMed: Controlling the cohesion of cement paste. PubMed: The self-setting properties and in vitro bioactivity of tricalcium silicate. PubMed: The influence of superplasticizers on the first steps of tricalcium silicate hydration studied by NMR techniques. PubMed: The constitution of mineral trioxide aggregate. PubMed: Preparation and characterization of novel tricalcium silicate bioceramics. PubMed: Characterization and preliminary assessment of a sorbent produced by accelerated mineral carbonation. PubMed: Adsorption and heterocoagulation of nonionic surfactants and latex particles on cement hydrates. PubMed: Age-dependent dynamics of water in hydrated cement paste. PubMed: Global hydration kinetics of tricalcium silicate cement. PubMed: Calcium hydroxide: its role in the fracture of tricalcium silicate paste.