urolithin C

6H-dibenzo[b,d]pyran-6-one, 3,8,9-trihydroxy-

CAS: 165393-06-6 C13 H8 O5 MW: 244.20276000

Identification

Nameurolithin C
CAS Number165393-06-6
FDA UNIISearch
Molecular FormulaC13 H8 O5
Molecular Weight244.20276000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 605.38 °C. @ 760.00 mm Hg (est)
Flash Point 470.00 °F. TCC ( 243.60 °C. ) (est)
logP (o/w) 1.615 (est)
Soluble in water, 2565 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for urolithin C usage levels up tonot for fragrance use.
Recommendation for urolithin C flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

pomegranate fruit

Synonyms

6H- dibenzo[b,d]pyran-6-one, 3,8,9-trihydroxy- 3,8,9- trihydroxybenzo[c]chromen-6-one PubMed: In Vitro Bioaccessibility, Human Gut Microbiota Metabolites and Hepatoprotective Potential of Chebulic Ellagitannins: A Case of Padma Hepaten(®) Formulation. PubMed: The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells. PubMed: Pilot walnut intervention study of urolithin bioavailability in human volunteers. PubMed: Influence of gut microbiota-derived ellagitannins' metabolites urolithins on pro-inflammatory activities of human neutrophils. PubMed: Role of human gut microbiota metabolism in the anti-inflammatory effect of traditionally used ellagitannin-rich plant materials. PubMed: Description of urolithin production capacity from ellagic acid of two human intestinal Gordonibacter species. PubMed: Phase-II metabolism limits the antiproliferative activity of urolithins in human colon cancer cells. PubMed: Effects of ellagitannin-rich berries on blood lipids, gut microbiota, and urolithin production in human subjects with symptoms of metabolic syndrome. PubMed: Extracts from Epilobium sp. herbs, their components and gut microbiota metabolites of Epilobium ellagitannins, urolithins, inhibit hormone-dependent prostate cancer cells-(LNCaP) proliferation and PSA secretion. PubMed: The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota. PubMed: Colon cancer chemopreventive activities of pomegranate ellagitannins and urolithins. PubMed: Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells. PubMed: Iberian pig as a model to clarify obscure points in the bioavailability and metabolism of ellagitannins in humans.