propylene glycol caprylate

octanoic acid, ester with 1,2-propanediol

C11 H22 O3 MW: 202.29394000

Identification

Namepropylene glycol caprylate
FDA UNIIRT9P9S09QI
Molecular FormulaC11 H22 O3
Molecular Weight202.29394000
Nikkaji NumberJ106.464I

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 298.85 °C. @ 760.00 mm Hg (est)
Flash Point 243.00 °F. TCC ( 117.30 °C. ) (est)
logP (o/w) 2.887 (est)
Soluble in water, 601.4 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysurfactant
Recommendation for propylene glycol caprylate usage levels up tonot for fragrance use.
Recommendation for propylene glycol caprylate flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

capmul 908P capmul PG-8 capmul PG-8 NF 2- hydroxypropyl octanoate octanoic acid monoester with 1,2-propane diol octanoic acid, 1,2-propyleneglycol ester octanoic acid, ester with 1,2-propanediol propylene glycol monocaprylate propylene glycol monooctanoate PubMed: Solid-nanoemulsion preconcentrate for oral delivery of paclitaxel: formulation design, biodistribution, and γ scintigraphy imaging. PubMed: Pharmacoscintigraphic evaluation of potential of lipid nanocarriers for nose-to-brain delivery of antidepressant drug. PubMed: Formulation and in vitro/in vivo evaluation of levodopa transdermal delivery systems. PubMed: In situ intestinal permeability and in vivo oral bioavailability of celecoxib in supersaturating self-emulsifying drug delivery system. PubMed: Application of Box-Behnken design in the preparation and optimization of fenofibrate-loaded self-microemulsifying drug delivery system (SMEDDS). PubMed: Transcutaneous immunization system using a hydrotropic formulation induces a potent antigen-specific antibody response. PubMed: Enhancement of oral bioavailability of fenofibrate by solid self-microemulsifying drug delivery systems. PubMed: Fabrication of a uniformly sized fenofibrate microemulsion by membrane emulsification. PubMed: Characterization of semi-solid Self-Emulsifying Drug Delivery Systems (SEDDS) of atorvastatin calcium by Raman image spectroscopy and chemometrics. PubMed: Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. PubMed: Application of hydrotropy to transdermal formulations: hydrotropic solubilization of polyol fatty acid monoesters in water and enhancement effect on skin permeation of 5-FU. PubMed: Temperature-induced gel formation of core/shell nanoparticles for the regeneration of ischemic heart. PubMed: Development of clinical dosage forms for a poorly water-soluble drug II: formulation and characterization of a novel solid microemulsion preconcentrate system for oral delivery of a poorly water-soluble drug. PubMed: Development of the ambroxol gels for enhanced transdermal delivery. PubMed: Dry adsorbed emulsion of simvastatin: optimization and in vivo advantage. PubMed: Formulation and evaluation of ketorolac transdermal systems. PubMed: Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. PubMed: The effect of vehicles and pressure sensitive adhesives on the percutaneous absorption of quercetin through the hairless mouse skin. PubMed: Transdermal delivery of ketorolac tromethamine: effects of vehicles and penetration enhancers. PubMed: Transdermal delivery of ondansetron hydrochloride: effects of vehicles and penetration enhancers. PubMed: In vitro percutaneous absorption of ondansetron hydrochloride from pressure-sensitive adhesive matrices through hairless mouse skin. PubMed: Effect of vehicles and enhancers on the in vitro permeation of melatonin through hairless mouse skin. PubMed: Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. PubMed: Characterization of the influence of polyol fatty acid esters on the permeation of diclofenac through rat skin. PubMed: Pharmacokinetic behaviour of sublingually administered 8-methoxypsoralen for PUVA therapy. PubMed: Heparin absorption across the intestine: effects of sodium N-[8-(2-hydroxybenzoyl)amino]caprylate in rat in situ intestinal instillations and in Caco-2 monolayers. PubMed: Effect of polyol fatty acid esters on diclofenac permeation through rat skin.