coleus forskohlii root extract
extract of the roots of coleus forskohlii
Identification
| Name | coleus forskohlii root extract |
| CAS Number | 223748-52-5 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | humectants |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for coleus forskohlii root extract usage levels up to | not for fragrance use. |
| Recommendation for coleus forskohlii root extract flavor usage levels up to | not for flavor use. |
American International Chemical, Inc.
Consistent sources
North American supplier for globally sourced ingredients.
Potential Uses
Natural Occurrence
Synonyms
extract of the roots of coleus forskohlii
plectranthus barbatus root extract
PubMed:
Coleusin factor, a novel anti-cancer diterpenoid, inhibits osteosarcoma growth by inducing bone morphogenetic protein-2 dependent differentiation.
PubMed:
Effect of chronic administration of forskolin on glycemia and oxidative stress in rats with and without experimental diabetes.
PubMed:
Eco-friendly synthesis of silver and gold nanoparticles with enhanced bactericidal activity and study of silver catalyzed reduction of 4-nitrophenol.
PubMed:
A Comparison of the Anti-Staphylococcus aureus Activity of Extracts from Commonly Used Medicinal Plants.
PubMed:
Adaptive expression of host cell wall degrading enzymes in fungal disease: an example from Fusarium root rot of medicinal Coleus.
PubMed:
Effect of Coleus forskohlii extract on cafeteria diet-induced obesity in rats.
PubMed:
Manoyl oxide (13R), the biosynthetic precursor of forskolin, is synthesized in specialized root cork cells in Coleus forskohlii.
PubMed:
In vitro plant development and root colonization of Coleus forskohlii by Piriformospora indica.
PubMed:
Cyclic AMP synergizes with butyrate in promoting β-defensin 9 expression in chickens.
PubMed:
[In vitro metabolism of forscolin isolated from Coleus forskohlii].
PubMed:
A review on botanical species and chemical compounds with appetite suppressing properties for body weight control.
PubMed:
Influence of dietary macronutrients on induction of hepatic drug metabolizing enzymes by Coleus forskohlii extract in mice.
PubMed:
Metabolic diversity in Coleus forskohlii Briq. of Indian subcontinent.
PubMed:
Hepatic cytochrome P450 mediates interaction between warfarin and Coleus forskohlii extract in vivo and in vitro.
PubMed:
Forskolin: upcoming antiglaucoma molecule.
PubMed:
Matrix solid-phase dispersion extraction for chromatographic analysis of labdane diterpenoids in Coleus forskohlii.
PubMed:
Dietary Coleus forskohlii extract generates dose-related hepatotoxicity in mice.
PubMed:
Synergy between Glomus fasciculatum and a beneficial Pseudomonas in reducing root diseases and improving yield and forskolin content in Coleus forskohlii Briq. under organic field conditions.
PubMed:
In vitro conservation of twenty-three overexploited medicinal plants belonging to the Indian sub continent.
PubMed:
Labdane-type diterpenoids from hairy root cultures of Coleus forskohlii, possible intermediates in the biosynthesis of forskolin.
PubMed:
The root endophyte fungus Piriformospora indica leads to early flowering, higher biomass and altered secondary metabolites of the medicinal plant, Coleus forskohlii.
PubMed:
Coleus forskohlii extract induces hepatic cytochrome P450 enzymes in mice.
PubMed:
Clinical efficacy of Coleus forskohlii (Willd.) Briq. (Makandi) in hypertension of geriatric population.
PubMed:
[Studies on the chemical constituents of Coleus forskohlii transplanted in Tongcheng and their antitumor activity].
PubMed:
Anti-HIV activity of Indian medicinal plants.
PubMed:
Isoforskolin pretreatment attenuates lipopolysaccharide-induced acute lung injury in animal models.
PubMed:
Oviposition deterrent activity from the ethanolic extract of Pongamia pinnata, Coleus forskohlii, and Datura stramonium leaves against Aedes aegypti and Culex quinquefaciatus.
PubMed:
Coleusin factor exerts cytotoxic activity by inducing G0/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells.
PubMed:
Oral administration of an association of forskolin, rutin and vitamins B1 and B2 potentiates the hypotonising effects of pharmacological treatments in POAG patients.
PubMed:
In vitro direct shoot regeneration from proximal, middle and distal segment of Coleus forskohlii leaf explants.
PubMed:
Effect of selected antiasthmatic plant constituents against micro organism causing upper respiratory tract infection.
PubMed:
[Studies on the chemical constituents of Coleus forskohlii].
PubMed:
[Chemical constituents in the introduced Coleus forskohlii].
PubMed:
Anti-HIV diterpenes from Coleus forskohlii.
PubMed:
Monoclonal antibodies against naturally occurring bioactive compounds.
PubMed:
Free amino acids in botanicals and botanical preparations.
PubMed:
Effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women.
PubMed:
Inhibition of tumor cell proliferation by Coleon C.
PubMed:
[Studies on HPLC-ELSD fingerprint of the Coleus forskohlii introduced in Tongcheng].
PubMed:
Diterpenes from Coleus forskohlii (WILLD.) BRIQ. (Labiatae).
PubMed:
Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro.
PubMed:
Two minor diterpene glycosides and an eudesman sesquiterpene from Coleus forskohlii.
PubMed:
Potential application of urea-derived herbicides as cytokinins in plant tissue culture.
PubMed:
Identification of a forskolin-like molecule in human renal cysts.
PubMed:
A forskolin derivative, FSK88, induces apoptosis in human gastric cancer BGC823 cells through caspase activation involving regulation of Bcl-2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release.
PubMed:
Three new diterpenoids from Coleus forskohlii Briq.
PubMed:
Antifungal activity of some coleus species growing in nilgiris.
PubMed:
Coleus forskohlii. Monograph.
PubMed:
[Studies on the chemical constituents in root of Coleus forskohlii].
PubMed:
Simple and rapid method for the isolation of forskolin from Coleus forskohlii by charcoal column chromatography.
PubMed:
Two new diterpenoids from Coleus forskohlii.
PubMed:
Influence of different AM-fungi on the growth, nutrition and forskolin content of Coleus forskohlii.
PubMed:
Effects of Coleus forskohlii on fat storage in ovariectomized rats.
PubMed:
Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq.
PubMed:
Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway.
PubMed:
Quantitative analysis of forskolin in Coleus forskohlii (Lamiaceae) by reversed-phase liquid chromatography.
PubMed:
Biotransformation of low-molecular-weight alcohols by Coleus forskohlii hairy root cultures.
PubMed:
Natural therapies for ocular disorders, part two: cataracts and glaucoma.
PubMed:
Establishment of forskolin yielding transformed cell suspension cultures of Coleus forskohlii as controlled by different factors.
PubMed:
Development of ELISA-analysis methods for the quantification of bioactive natural products in plants, phytomedicines and in humans or similar.
PubMed:
Forskolin synthesis in in vitro cultures of Coleus forskohlii Briq transformed with Agrobacterium tumefaciens.
PubMed:
Rapid analysis of small samples containing forskolin using monoclonal antibodies.
PubMed:
Production of Forskolin by Axenic Coleus forskohlii Roots Cultivated in Shake Flasks and 20-l Glass Jar Bioreactors*.
PubMed:
Production of Forskolin in in vitro Cultures of Coleus forskohlii.
PubMed:
In vitro propagation of Coleus forskohlii Briq., a threatened medicinal plant.
PubMed:
In vitro propagation of Coleus forskohlii Briq. for forskolin synthesis.
PubMed:
Insulin and glucagon releasing activity of coleonol (forskolin) and its effect on blood glucose level in normal and alloxan diabetic rats.
PubMed:
The effect of adenylate cyclase stimulation on endocochlear potential in the guinea pig.
PubMed:
Chonemorphine, stigmasterol, and ecdysterone: steroids isolated through bioassay-directed plant screening programs.
PubMed:
Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep.
PubMed:
Variation in forskolin content in the roots of Coleus forskohlii.
PubMed:
Formation of forskolin by suspension cultures of Coleus forskohlii.
PubMed:
Relaxant effects of forskolin on guinea pig tracheal smooth muscle.
PubMed:
Inhibition of IgE-mediated release of histamine and peptide leukotriene from human basophils and mast cells by forskolin.
PubMed:
[Protective effect of forskolin in acetylcholine provocation in healthy probands. Comparison of 2 doses with fenoterol and placebo].
PubMed:
Forskolin: from an ayurvedic remedy to a modern agent.
PubMed:
Forskolin stimulation of naphthylamidase in guinea pig thyroid sections detected with a cytochemical bioassay.
PubMed:
Forskolin lowers intraocular pressure by reducing aqueous inflow.
PubMed:
Forskolin: a potential antimetastatic agent.
PubMed:
Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives.
PubMed:
Forskolin stimulation of acid and pepsinogen secretion by gastric glands.
PubMed:
The action of forskolin on muscle cells is modified by hormones, calcium ions and calcium antagonists.
PubMed:
[Zum Mechanismus der positiv inotropen und gefässerweiternden Wirkung von Forskolin aus Coleus forskohlii.]
PubMed:
Coleonol and forskolin from Coleus forskohlii.
PubMed:
The positive inotropic-acting forskolin, a potent adenylate cyclase activator.
PubMed:
Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii.