synephrine hydrochloride
benzenemethanol, 4-hydroxy-a-[(methylamino)methyl]-, hydrochloride (1:1)
Identification
| Name | synephrine hydrochloride |
| CAS Number | 5985-28-4 |
| EINECS | 227-804-6 |
| FDA UNII | EN5D1IH09S |
| Molecular Formula | C9 H14 Cl N O2 |
| Molecular Weight | 203.66798000 |
| MDL Number | MFCD00050566 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 341.10 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000032 mmHg @ 25.00 °C. (est) |
| Flash Point | 326.00 °F. TCC ( 163.40 °C. ) (est) |
| logP (o/w) | -0.030 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | subcutaneous-guinea pig LDLo 500 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for synephrine hydrochloride usage levels up to | not for fragrance use. |
| Recommendation for synephrine hydrochloride flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzenemethanol, 4-hydroxy-a-((methylamino)methyl)-, hydrochloride
benzenemethanol, 4-hydroxy-a-[(methylamino)methyl]-, hydrochloride (1:1)
benzyl alcohol, p-hydroxy-a-((methylamino)methyl)-, hydrochloride
[2-
hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium;chloride
4-(1-
hydroxy-2-(methylamino)ethyl)phenol hydrochloride
4-[1-
hydroxy-2-(methylamino)ethyl]phenol hydrochloride
4-[1-
hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1)
4-
hydroxy-a-((methylamino)methyl)benzyl alcohol hydrochloride
p-
hydroxy-a-(methylaminomethyl)benzyl alcohol hydrochloride
4-
hydroxy-a-[(methylamino)methyl]benzyl alcohol hydrochloride
p-
methylaminoethanol phenol hydrochloride
synephrine HCl
synephrinehydrochloride
PubMed:
The effects of induced hypertension and acute graded compression on impulse propagation in the spinal nerve roots of the pig.
PubMed:
NTP Toxicology and Carcinogenesis Studies of Phenylephrine Hydrochloride (CAS No. 61-76-7) in F344/N Rats and B6C3F1 Mice (Feed Studies).
PubMed:
The mammalian metabolism of R-(-)-m-synephrine.
PubMed:
Cocaine toxicity during dacryocystorhinostomy.
PubMed:
The treatment of prolonged arterial hypotension with continuous intravenous infusions of neo-synephrine hydrochloride.
PubMed:
Use of phenylephrine hydrochloride, neo-synephrine hydrochloride, in ophthalmology.