aloe emodin
1,8-dihydroxy-3-(hydroxymethyl)-9,10-anthraquinone
Identification
| Name | aloe emodin |
| CAS Number | 481-72-1 |
| EINECS | 207-571-7 |
| FDA UNII | C8IYT9CR7C |
| Molecular Formula | C15 H10 O5 |
| Molecular Weight | 270.24070000 |
| MDL Number | MFCD00017373 |
| Nikkaji Number | J5.780K |
| Beilstein | 2059062 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 223.50 °C. @ 760.00 mm Hg |
| Boiling Point | 568.82 °C. @ 760.00 mm Hg (est) |
| Flash Point | 593.00 °F. TCC ( 311.90 °C. ) (est) |
| logP (o/w) | 3.254 (est) |
| Soluble in | water, 45.8 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for aloe emodin usage levels up to | not for fragrance use. |
| Recommendation for aloe emodin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
aloe-emodin
aloe-emodine
aloeemodin
aloeemodin:9,10-Anthracenedione,1,8-dihydroxy-3-(hydroxymethyl)-,
9,10-
anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-
9,10-
anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- (9CI)
anthraquinone, 1,8-dihydroxy-3-hydroxymethyl-
1,8-
dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
1,8-
dihydroxy-3-(hydroxymethyl)-9,10-anthraquinone
1,8-
dihydroxy-3-(hydroxymethyl)anthra-9,10-quinone
1,8-
dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione
1,8-
dihydroxy-3-(hydroxymethyl)anthraquinone
1,8-
dihydroxy-3-hydroxymethyl-anthraquinone
1,8-
dihydroxy-3-hydroxymethylanthraquinone
emodine
3-
hydroxymethylchrysazine
rhabarberone
PubMed:
Chemical constituents of Aloe barbadensis Miller and their inhibitory effects on phosphodiesterase-4D.
PubMed:
Assessment of antibacterial properties and the active ingredient of plant extracts and its effect on the performance of crucian carp (Carassius auratus gibelio var. E'erqisi, Bloch).
PubMed:
Comment on "The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells by Zhu et al. (2012).
PubMed:
Cell-type dependent response of melanoma cells to aloe emodin.
PubMed:
Aloe-emodin inhibits adipocyte differentiation and maturation during in vitro human mesenchymal stem cell adipogenesis.
PubMed:
The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells.
PubMed:
A novel sensitive detection platform for antitumor herbal drug aloe-emodin based on the graphene modified electrode.
PubMed:
Intestinal absorption of aloin, aloe-emodin, and aloesin; A comparative study using two in vitro absorption models.
PubMed:
Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages.
PubMed:
Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
PubMed:
Anti-angiogenic effects of rhubarb and its anthraquinone derivatives.
PubMed:
Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice.
PubMed:
Aloe-emodin-induced apoptosis in human gastric carcinoma cells.
PubMed:
Chemical constituents of cape aloe and their synergistic growth-inhibiting effect on Ehrlich ascites tumor cells.
PubMed:
Rapid separation and determination of structurally related anthraquinones in Rhubarb by pressurized capillary electrochromatography.
PubMed:
Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway.
PubMed:
Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2).
PubMed:
Anthraquinones isolated from Cassia tora (Leguminosae) seed show an antifungal property against phytopathogenic fungi.
PubMed:
Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells.
PubMed:
In vitro studies on the photobiological properties of aloe emodin and aloin A.
PubMed:
[Contents of barbaloin-related compounds in aloe drinks and their change during storage].
PubMed:
Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated?