pramoxine hydrochloride
morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride (1:1)
Identification
| Name | pramoxine hydrochloride |
| CAS Number | 637-58-1 |
| EINECS | 211-293-1 |
| FDA UNII | 88AYB867L5 |
| Molecular Formula | C17 H28 Cl N O3 |
| Molecular Weight | 329.86676000 |
| MDL Number | MFCD00054323 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 181.00 °C. @ 760.00 mm Hg (est) |
| Boiling Point | 427.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000000 mmHg @ 25.00 °C. (est) |
| Flash Point | 254.00 °F. TCC ( 123.50 °C. ) (est) |
| logP (o/w) | 3.477 (est) |
| Soluble in | water, 190.6 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-guinea pig LDLo 109 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 1470 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for pramoxine hydrochloride usage levels up to | not for fragrance use. |
| Recommendation for pramoxine hydrochloride flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Charkit Chemical Corporation
The Specialty Chemical Specialists
Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
4-(3-(p-
butoxyphenoxy)propyl)morpholine hydrochloride
4-[3-(4-
butoxyphenoxy)propyl]morpholine hydrochloride
4-[3-(p-
butoxyphenoxy)propyl]morpholine hydrochloride
4-[3-(4-
butoxyphenoxy)propyl]morpholine hydrochloride (1:1)
4-[3-(4-
butoxyphenoxy)propyl]morpholine;hydrochloride
p-
butoxyphenyl g-morpholinopropyl ether hydrochloride
morpholine, 4-(3-(4-butoxyphenoxy)propyl)-, hydrochloride
morpholine, 4-(3-(p-butoxyphenoxy)propyl)-, hydrochloride
morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride (1:1)
g-
morpholinopropyl 4-N-butoxyphenyl ether hydrochloride
pramocaine hydrochloride
pramoxine HCl
proctocream-HC
proxazocain hydrochloride
tronolane
tronothane hydrochloride
PubMed:
[A case of prostate cancer presenting as extensive abdominal metastasis].
PubMed:
Efficacy and onset of action of hydrocortisone acetate 2.5% and pramoxine hydrochloride 1% lotion for the management of pruritus: results of a pilot study.
PubMed:
A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients.
PubMed:
An evaluation of the moisturizing and anti-itch effects of a lactic acid and pramoxine hydrochloride cream.
PubMed:
Anorectal drug products for over-the-counter human use. Final rule.
PubMed:
The safety of pramoxine hydrochloride when used as a topical (surface) anesthetic.
PubMed:
Cost analysis of a mucoadhesive foam versus conventional treatment for postepisiotomy patients.
PubMed:
Clinical evaluation of a topical anaesthetic preparation (pramoxine hydrochloride and hydrocortisone) in post-episiotomy pain relief.
PubMed:
Rapid high-performance liquid chromatographic determination of pramoxine hydrochloride in topical cream and suppositories.
PubMed:
Topical pramoxine and hydrocortisone foam versus placebo in relief of post partum episiotomy symptoms and wound healing.
PubMed:
Allergic reactions to topical (surface) anesthetics with reference to the safety of tronothane (pramoxine hydrochloride).
PubMed:
High-pressure liquid chromatographic analysis of pramoxine hydrochloride in high lipoid aerosol foam dosage form.
PubMed:
[Local anesthetic activity of pramoxine hydrochloride (tronothane)].
PubMed:
Tronothane hydrochloride (pramoxine hydrochloride) in the control of pruritus.
PubMed:
The pharmacology of pramoxine hydrochloride: a new topical local anesthetic.