vidarabine

adenine, 9b-D-arabinofuranosyl-

CAS: 5536-17-4 C10 H13 N5 O4 MW: 267.24541000

Identification

Namevidarabine
CAS Number5536-17-4
EINECS226-893-9
FDA UNII3XQD2MEW34
Molecular FormulaC10 H13 N5 O4
Molecular Weight267.24541000
MDL NumberMFCD00065471
Nikkaji NumberJ3.415K
Beilstein0624881
XlogP3-1.10 (est)

Regulatory

Physical Properties

Appearance white crystalline powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 257.00 °C. @ 760.00 mm Hg
Boiling Point 676.27 °C. @ 760.00 mm Hg (est)
Vapor Pressure 6.000000 mmHg @ 25.00 °C. (est)
Flash Point 685.00 °F. TCC ( 362.80 °C. ) (est)
logP (o/w) -0.755 (est)
Soluble in water, 8228 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintravenous-human TDLo 300 ug/kg
Dermal Toxicitysubcutaneous-mouse LD50 5086 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for vidarabine usage levels up tonot for fragrance use.
Recommendation for vidarabine flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

adenine 9-b-D-arabinofuranoside adenine-9-b-D-arabinofuranoside adenine-b-D-arabinofuranoside adenine, 9-b-D-arabinofuranosyl- adenine, 9b-D-arabinofuranosyl- 6- amino-9-b-D-arabinofuranosylpurine (2R,3S,4S,5R)-2-(6- amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (2R,3S,4S,5R)-2-(6- aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 9-b-D- arabinofuranosyl-9H-purin-6-amine (9CI) 9-b-D- arabinofuranosyl-9H-purine-6-amine 9-b-D- arabinofuranosyladenine 9b-D- arabinofuranosyladenine (+)- cyclaradine spongoadenosine vidarabin vidarabinum PubMed: Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. PubMed: The pleiotropic flavonoid quercetin: from its metabolism to the inhibition of protein kinases in chronic lymphocytic leukemia. PubMed: Transplant-acquired food allergy (TAFA) following cord blood stem cell transplantation in two adult patients with haematological malignancies. PubMed: 'Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption'. PubMed: Drug repurposing for gastrointestinal stromal tumor. PubMed: Rituximab in chronic lymphocytic leukemia. PubMed: U.S. Food and drug administration approval: rituximab in combination with fludarabine and cyclophosphamide for the treatment of patients with chronic lymphocytic leukemia. PubMed: Ofatumumab in the treatment of chronic lymphocytic leukemia. PubMed: Quercetin induced apoptosis in association with death receptors and fludarabine in cells isolated from chronic lymphocytic leukaemia patients. PubMed: U.S. Food and Drug Administration approval: ofatumumab for the treatment of patients with chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab. PubMed: The odyssey of marine pharmaceuticals: a current pipeline perspective. PubMed: Leptin inhibits rosiglitazone-induced adipogenesis in murine primary adipocytes. PubMed: Nelarabine: a new purine analog in the treatment of hematologic malignancies. PubMed: Successful bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning. PubMed: Innovations in antineoplastic therapy. PubMed: The bioavailability of oral fludarabine phosphate is unaffected by food. PubMed: Emerging information on the use of rituximab in chronic lymphocytic leukemia. PubMed: Hemolytic anemia after fludarabine therapy for chronic lymphocytic leukemia. PubMed: Late listeriosis after fludarabine plus prednisone treatment. PubMed: Advances in therapy for hairy cell leukemia. A review. PubMed: From the Food and Drug Administration. PubMed: Fludarabine phosphate: a synthetic purine antimetabolite with significant activity against lymphoid malignancies. PubMed: Purification and characterization of a novel nucleoside phosphorylase from a Klebsiella sp. and its use in the enzymatic production of adenine arabinoside. PubMed: From the Food and Drug Administration. PubMed: [The glomerulopathies of cirrhosis of the liver]. PubMed: Projections on the use of antiviral chemicals in animals. PubMed: Vidarabine approved for herpes simplex virus encephalitis.