oleuropein

2-(3,4- dihydroxyphenyl)ethyl (2S-(2alpha,3E,4beta))-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetate oleuroperin 2H- pyran-4-acetic acid, 3-ethylidene-2-(.beta.-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2S,3E,4S)- PubMed: Characteristics of oleuropeinolytic strains of Lactobacillus plantarum group and influence on phenolic compounds in table olives elaborated under reduced salt conditions. PubMed: Phytochemicals and other characteristics of croatian monovarietal extra virgin olive oils from oblica, lastovka and levantinka varieties. PubMed: Ultrahigh-pressure liquid chromatography triple-quadrupole tandem mass spectrometry quantitation of polyphenols and secoiridoids in california-style black ripe olives and dry salt-cured olives. PubMed: Phenolic profile characterization of chemlali olive stones by liquid chromatography-ion trap mass spectrometry. PubMed: Oleuropein Suppresses LPS-Induced Inflammatory Responses in RAW 264.7 Cell and Zebrafish. PubMed: Biotechnological innovations for table olives. PubMed: Evidence of oleuropein degradation by olive leaf protein extract. PubMed: Isolation and Characterization of a Secoiridoid Derivative from Two-Phase Olive Waste (Alperujo). PubMed: Whole Lyophilized Olives as Sources of Unexpectedly High Amounts of Secoiridoids: The Case of Three Tuscan Cultivars. PubMed: Nutraceuticals and amyloid neurodegenerative diseases: a focus on natural phenols. PubMed: Computer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins. PubMed: Combined use of nitrogen and coatings to improve the quality of mechanically harvested Manzanilla olives. PubMed: Recovering bioactive compounds from olive oil filter cake by advanced extraction techniques. PubMed: Endogenous enzymes involved in the transformation of oleuropein in Spanish table olive varieties. PubMed: Oleuropein attenuates visceral adiposity in high-fat diet-induced obese mice through the modulation of WNT10b- and galanin-mediated signalings. PubMed: The role of structural C--H compared with phenolic OH sites on the antioxidant activity of oleuropein and its derivatives as a great non-flavonoid family of the olive components: a DFT study. PubMed: Faecal microbial metabolism of olive oil phenolic compounds: in vitro and in vivo approaches. PubMed: 3,4-DHPEA-EA from Olea Europaea L. is effective against standard and clinical isolates of Staphylococcus sp. PubMed: Influence of olive leaf processing on the bioaccessibility of bioactive polyphenols. PubMed: A new extraction approach to correct the effect of apparent increase in the secoiridoid content after filtration of virgin olive oil. PubMed: Biomimetic synthesis and antioxidant evaluation of 3,4-DHPEA-EDA [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate]. PubMed: Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice. PubMed: Oleuropein as a bioactive constituent added in milk and yogurt. PubMed: Effects of the dietary incorporation of olive leaves on growth performance, digestibility, blood parameters and meat quality of growing pigs. PubMed: High-resolution mass spectrometry to evaluate the influence of cross-breeding segregating populations on the phenolic profile of virgin olive oils. PubMed: Minor polar compounds in extra virgin olive oil: correlation between HPLC-DAD-MS and the Folin-Ciocalteu spectrophotometric method. PubMed: Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers. PubMed: Isolation of megaritolactones and other bioactive metabolites from 'megaritiki' table olives and debittering water. PubMed: Antioxidant capacity of individual and combined virgin olive oil minor compounds evaluated at mild temperature (25 and 40°C) as compared to accelerated and antiradical assays. PubMed: Radical-scavenging compounds from olive tree (Olea europaea L.) wood. PubMed: Employing Alzheimer disease animal models for translational research: focus on dietary components. PubMed: Bioavailability of phenolics from an oleuropein-rich olive (Olea europaea) leaf extract and its acute effect on plasma antioxidant status: comparison between pre- and postmenopausal women. PubMed: Nutrition and healthy ageing: calorie restriction or polyphenol-rich "MediterrAsian" diet? PubMed: Olive leaf extracts are a natural source of advanced glycation end product inhibitors. PubMed: Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells. PubMed: Effects of certain polyphenols and extracts on furans and acrylamide formation in model system, and total furans during storage. PubMed: Insight into virgin olive oil secoiridoids characterization by high-resolution mass spectrometry and accurate mass measurements. PubMed: Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract. PubMed: DPPH assay of vegetable oils and model antioxidants in protic and aprotic solvents. PubMed: Selection of Lactobacillus plantarum strains to use as starters in fermented table olives: Oleuropeinase activity and phage sensitivity. PubMed: Antioxidant activity of phenolic fractions in olive mill wastewater. PubMed: Combined effect of starter culture and temperature on phenolic compounds during fermentation of Taggiasca black olives. PubMed: A validated method for the determination of selected phenolics in olive oil using high-performance liquid chromatography with coulometric electrochemical detection and a fused-core column. PubMed: Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents. PubMed: Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells. PubMed: Comprehensive analysis of polyphenols in 55 extra virgin olive oils by HPLC-ECD and their correlation with antioxidant activities. PubMed: Microchip electrophoresis with amperometric detection for a novel determination of phenolic compounds in olive oil. PubMed: Influence of harvest year, cultivar and geographical origin on Greek extra virgin olive oils composition: a study by NMR spectroscopy and biometric analysis. PubMed: Analytical evaluation of two monovarietal virgin olive oils cultivated in the south of Tunisia: Jemri-Bouchouka and Chemlali-Tataouin cultivars. PubMed: Characterisation and phenolic profiles of two rare olive oils from southern Tunisia: Dhokar and Gemri-Dhokar cultivars. PubMed: High-performance liquid chromatography-mass spectrometry profiling of phenolic compounds for evaluation of olive oil bitterness and pungency. PubMed: Improvement of oleuropein extractability by optimising steam blanching process as pre-treatment of olive leaf extraction via response surface methodology. PubMed: Reuse of drinking water treatment sludge for olive oil mill wastewater treatment. PubMed: Factors influencing phenolic compounds in table olives (Olea europaea). PubMed: β-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices. PubMed: Feasible application of a portable NIR-AOTF tool for on-field prediction of phenolic compounds during the ripening of olives for oil production. PubMed: Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake. PubMed: Oleuropein ameliorates acute colitis in mice. PubMed: Wastes generated during the storage of extra virgin olive oil as a natural source of phenolic compounds. PubMed: Phenolic composition, isolation, and structure of a new deoxyloganic acid derivative from Dhokar and Gemri-Dhokar olive cultivars. PubMed: Gamma irradiation of air-dried olive leaves: Effective decontamination and impact on the antioxidative properties and on phenolic compounds. PubMed: Simultaneous separation and purification of flavonoids and oleuropein from Olea europaea L. (olive) leaves using macroporous resin. PubMed: New possibilities for the valorization of olive oil by-products. PubMed: The activity of healthy olive microbiota during virgin olive oil extraction influences oil chemical composition. PubMed: Oleuropein and derivatives from olives as Tau aggregation inhibitors. PubMed: High-throughput assay of oleopentanedialdheydes in extra virgin olive oil by the UHPLC-ESI-MS/MS and isotope dilution methods. PubMed: Influence of Eriophyid mites (Aculus olearius Castagnoli and Aceria oleae (Nalepa) (Acarina: Eriophyidae)) on some physical and chemical characteristics of Ayvalık variety olive fruit. PubMed: Use of multivariate statistical techniques to optimize the simultaneous separation of 13 phenolic compounds from extra-virgin olive oil by capillary electrophoresis. PubMed: Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice. PubMed: Wound repair potential of Olea europaea L. leaf extracts revealed by in vivo experimental models and comparative evaluation of the extracts' antioxidant activity. PubMed: Effects of conventional heating on the stability of major olive oil phenolic compounds by tandem mass spectrometry and isotope dilution assay. PubMed: Metabolites involved in oleuropein accumulation and degradation in fruits of Olea europaea L.: Hojiblanca and Arbequina varieties. PubMed: Comparative study of virgin olive oil quality from single varieties cultivated in Chile and Spain. PubMed: Phenol metabolism in the leaves of the olive tree (Olea europaea L.) cv. Picual, Verdial, Arbequina, and Frantoio during ripening. PubMed: Hydroxytyrosol rich extract from olive leaves modulates cell cycle progression in MCF-7 human breast cancer cells. PubMed: Characterization of antioxidant olive oil biophenols by spectroscopic methods. PubMed: Hepatoprotective effect of oleuropein in mice: mechanisms uncovered by gene expression profiling. PubMed: Separation and identification of phenolic compounds of extra virgin olive oil from Olea europaea L. by HPLC-DAD-SPE-NMR/MS. Identification of a new diastereoisomer of the aldehydic form of oleuropein aglycone. PubMed: Sensory quality of functional beverages: bitterness perception and bitter masking of olive leaf extract fortified fruit smoothies. PubMed: HPLC analysis of oleuropein, hydroxytyrosol, and tyrosol in stems and roots of Olea europaea L. cv. Picual during ripening. PubMed: Oil content, phenolic profiling and antioxidant potential of Tunisian olive drupes. PubMed: Effect of olive ripeness on chemical properties and phenolic composition of Chétoui virgin olive oil. PubMed: Qualitative screening of phenolic compounds in olive leaf extracts by hyphenated liquid chromatography and preliminary evaluation of cytotoxic activity against human breast cancer cells. PubMed: Contribution of flavonoids to the overall radical scavenging activity of olive (Olea europaea L.) leaf polar extracts. PubMed: Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. PubMed: Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling. PubMed: Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation. PubMed: Bactericidal activity of glutaraldehyde-like compounds from olive products. PubMed: Identification of Throuba Thassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein. PubMed: Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-induced hemolysis. PubMed: Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors. PubMed: Olive tree (Olea europaea) leaves: potential beneficial effects on human health. PubMed: Tentative characterization of novel phenolic compounds in extra virgin olive oils by rapid-resolution liquid chromatography coupled with mass spectrometry. PubMed: Phenylalanine ammonia-lyase, polyphenol oxidase, and phenol concentration in fruits of Olea europaea L. cv. Picual, Verdial, Arbequina, and Frantoio during ripening. PubMed: Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation. PubMed: Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats. PubMed: Purification and characterization of an olive fruit beta-glucosidase involved in the biosynthesis of virgin olive oil phenolics. PubMed: Evaluation of potential genotoxicity of virgin olive oil (VOO) using the drosophila wing-spot test. PubMed: Effects of olive oil polyphenols on erythrocyte oxidative damage. PubMed: Effect of malaxation conditions on phenol and volatile profiles in olive paste and the corresponding virgin olive oils (Olea europaea L. Cv. Cornicabra). PubMed: Phenolic composition, sugar contents and antioxidant activity of Tunisian sweet olive cultivar with regard to fruit ripening. PubMed: Impact of sampling parameters on the radical scavenging potential of olive (Olea europaea L.) leaves. PubMed: Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells. PubMed: Debittering of olives by polyphenol oxidation. PubMed: Influence of the decrease in oxygen during malaxation of olive paste on the composition of volatiles and phenolic compounds in virgin olive oil. PubMed: Nutritional benefit of olive oil: the biological effects of hydroxytyrosol and its arylating quinone adducts. PubMed: Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach. PubMed: Isolation and characterization of a new hydroxytyrosol derivative from olive (Olea europaea) leaves. PubMed: Tunisian table olive phenolic compounds and their antioxidant capacity. PubMed: Liquid-liquid extraction for the enrichment of edible oils with phenols from olive leaf extracts. PubMed: Changes in virgin olive oil quality during low-temperature fruit storage. PubMed: Effect of the maturation process on the phenolic fractions, fatty acids, and antioxidant activity of the Chétoui olive fruit cultivar. PubMed: Phenolic compounds and antioxidant activity of Italian extra virgin olive oil Monti Iblei. PubMed: Retention and distribution of polyphenols after pan-frying of French fries in oils enriched with olive leaf extract. PubMed: Main antimicrobial compounds in table olives. PubMed: Encapsulation of olive leaf extract in beta-cyclodextrin. PubMed: Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. PubMed: New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol. PubMed: Effect of olive stoning on the volatile and phenolic composition of virgin olive oil. PubMed: Irrigation effects on quality, phenolic composition, and selected volatiles of virgin olive oils cv. Leccino. PubMed: Evaluation of the influence of thermal oxidation on the phenolic composition and on the antioxidant activity of extra-virgin olive oils. PubMed: Small branches of olive tree: a source of biophenols complementary to olive leaves. PubMed: Optimum bacteriocin production by Lactobacillus plantarum 17.2b requires absence of NaCl and apparently follows a mixed metabolite kinetics. PubMed: High-yielding preparation of a stable precursor of hydroxytyrosol by total synthesis and from the natural glycoside oleuropein. PubMed: Dysfunctionality of the xylem in Olea europaea L. Plants associated with the infection process by Verticillium dahliae Kleb. Role of phenolic compounds in plant defense mechanism. PubMed: Novel secoiridoids with antioxidant activity from Australian olive mill waste. PubMed: Bioscreening of Australian olive mill waste extracts: biophenol content, antioxidant, antimicrobial and molluscicidal activities. PubMed: 1H NMR monitoring of the canine metabolic profile after oral administration of xenobiotics using multivariate statistics. PubMed: Adsorption of olive leaf (Olea europaea L.) antioxidants on silk fibroin. PubMed: Evolution of minor polar compounds and antioxidant capacity during storage of bottled extra virgin olive oil. PubMed: Secondary metabolism of olive secoiridoids. New microcomponents detected in drupes by electrospray ionization and high-resolution tandem mass spectrometry. PubMed: Rapid quantification of the phenolic fraction of Spanish virgin olive oils by capillary electrophoresis with UV detection. PubMed: Pro-oxidant activity of oleuropein determined in vitro by electron spin resonance spin-trapping methodology. PubMed: Lipase production by yeasts from extra virgin olive oil. PubMed: Comparison of the concentrations of phenolic compounds in olive oils and other plant oils: correlation with antimicrobial activity. PubMed: Protective effects of extra virgin olive oil phenolics on oxidative stability in the presence or absence of copper ions. PubMed: The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformation. PubMed: The use of Lactobacillus pentosus 1MO to shorten the debittering process time of black table olives (Cv. Itrana and Leccino): a pilot-scale application. PubMed: Effects of copper on the antioxidant activity of olive polyphenols in bulk oil and oil-in-water emulsions. PubMed: Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation. PubMed: Antioxidant effect of two virgin olive oils depends on the concentration and composition of minor polar compounds. PubMed: Effect of storage on secoiridoid and tocopherol contents and antioxidant activity of monovarietal extra virgin olive oils. PubMed: Evaluation of phenolic compounds in virgin olive oil by direct injection in high-performance liquid chromatography with fluorometric detection. PubMed: Factors affecting the contents of iridoid oleuropein in olive leaves (Olea europaea L.). PubMed: Investigation of Australian olive mill waste for recovery of biophenols. PubMed: Discrimination of olive oils and fruits into cultivars and maturity stages based on phenolic and volatile compounds. PubMed: Absolute method for the assay of oleuropein in olive oils by atmospheric pressure chemical ionization tandem mass spectrometry. PubMed: Development of a sensitive and specific solid phase extraction--gas chromatography-tandem mass spectrometry method for the determination of elenolic acid, hydroxytyrosol, and tyrosol in rat urine. PubMed: Inhibition of Staphylococcus aureus by oleuropein is mediated by hydrogen peroxide. PubMed: Kinetic study of the physicochemical and microbiological changes in "seasoned" olives during the shelf-life period. PubMed: Characterization and quantification of phenolic compounds in olive oils by solid-phase extraction, HPLC-DAD, and HPLC-MS/MS. PubMed: Antioxidant and anti-atherogenic activities of olive oil phenolics. PubMed: Interactions of ferric ions with olive oil phenolic compounds. PubMed: Antioxidant activity of olive pulp and olive oil phenolic compounds of the arbequina cultivar. PubMed: Secoiridoids, tocopherols, and antioxidant activity of monovarietal extra virgin olive oils extracted from destoned fruits. PubMed: Identification and antioxidant potential of flavonoids and low molecular weight phenols in olive cultivar chemlali growing in Tunisia. PubMed: Qualitative and semiquantitative analysis of phenolic compounds in extra virgin olive oils as a function of the ripening degree of olive fruits by different analytical techniques. PubMed: Comparative study on phenolic content and antioxidant activity during maturation of the olive cultivar Chemlali from Tunisia. PubMed: Contribution of the phenolic fraction to the antioxidant activity and oxidative stability of olive oil. PubMed: Phenolic antioxidants and the protection of low density lipoprotein from peroxynitrite-mediated oxidations at physiologic CO2. PubMed: Comparison of the radical scavenging potential of polar and lipidic fractions of olive oil and other vegetable oils under normal conditions and after thermal treatment. PubMed: Polyphenol changes during fermentation of naturally black olives. PubMed: LC-MS investigation of oxidation products of phenolic antioxidants. PubMed: Antioxidant effect of phenolic compounds, alpha-tocopherol, and other minor components in virgin olive oil. PubMed: Main polyphenols in the bitter taste of virgin olive oil. Structural confirmation by on-line high-performance liquid chromatography electrospray ionization mass spectrometry. PubMed: Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration. PubMed: Quantitative changes in phenolic content during physiological development of the olive (Olea europaea) cultivar Hardy's Mammoth. PubMed: Sensory properties of virgin olive oil polyphenols: identification of deacetoxy-ligstroside aglycon as a key contributor to pungency. PubMed: Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidation. PubMed: Radioprotective effects in vivo of phenolics extracted from Olea europaea L. leaves against X-ray-induced chromosomal damage: comparative study versus several flavonoids and sulfur-containing compounds. PubMed: Comparison of the antioxidant activities of extra virgin olive oils. PubMed: Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method. PubMed: Phenolic compounds profile of cornicabra virgin olive oil. PubMed: Identification of phenolic compounds in tissues of the novel olive cultivar hardy's mammoth. PubMed: Deterioration of natural antioxidant species of vegetable edible oils during the domestic deep-frying and pan-frying of potatoes. PubMed: Biological properties of olive oil phytochemicals. PubMed: Microbiological activity in stored olive oil. PubMed: Partition behavior of virgin olive oil phenolic compounds in oil-brine mixtures during thermal processing for fish canning. PubMed: Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants. PubMed: Supplementation of plasma with olive oil phenols and extracts: influence on LDL oxidation. PubMed: Partitioning of olive oil antioxidants between oil and water phases. PubMed: Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts. PubMed: Changes in the phenolic composition of virgin olive oil from young trees (Olea europaea L. cv. Arbequina) grown under linear irrigation strategies. PubMed: Isolation and characterization of the antioxidant component 3,4-dihydroxyphenylethyl 4-formyl-3-formylmethyl-4-hexenoate from olive (Olea europaea) leaves. PubMed: Inactivation of cytochrome P450 by the food-derived complex phenol oleuropein. PubMed: Antioxidant activity of the main bioactive derivatives from oleuropein hydrolysis by hyperthermophilic beta-glycosidase. PubMed: Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols. PubMed: Effect of enzyme treatment during mechanical extraction of olive oil on phenolic compounds and polysaccharides. PubMed: Modulation of the biosynthesis of some phenolic compounds in Olea europaea L. fruits: their influence on olive oil quality. PubMed: Rapid high-performance liquid chromatography analysis for the quantitative determination of oleuropein in Olea europaea leaves. PubMed: Phenolic Compounds in Different Olive Varieties. PubMed: HPLC analysis of flavonoids and secoiridoids in leaves of Ligustrum vulgare L. (Oleaceae). PubMed: Oleuropein site selective hydrolysis by technomimetic nuclear magnetic resonance experiments. PubMed: Comparison among differential pulse voltammetry, amperometric biosensor, and HPLC/DAD analysis for polyphenol determination. PubMed: Rapid evaluation of phenolic component profile and analysis of oleuropein aglycon in olive oil by atmospheric pressure chemical ionization-mass spectrometry (APCI-MS). PubMed: Protective effect of oleuropein, an olive oil biophenol, on low density lipoprotein oxidizability in rabbits. PubMed: NMR experiments of oleuropein biomimetic hydrolysis. PubMed: Phenolic compounds in Spanish olive oils. PubMed: Bioactive derivatives of oleuropein from olive fruits. PubMed: Polyphenolic content in five tuscany cultivars of Olea europaea L. PubMed: Quantitation of oleuropein in virgin olive oil by ionspray mass spectrometry-selected reaction monitoring. PubMed: Phenolic compounds of olive fruit: one- and two-dimensional nuclear magnetic resonance characterization of Nüzhenide and its distribution in the constitutive parts of fruit. PubMed: On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. PubMed: Modelling the effectiveness of a natural antimicrobial on Salmonella enteritidis as a function of concentration, temperature and pH, using conductance measurements. PubMed: Inhibition of Salmonella enteritidis by oleuropein in broth and in a model food system. PubMed: Effect of phenolic compounds and oleuropein on the germination of Bacillus cereus T spores. PubMed: Utilization of oleuropein by microorganisms associated with olive fermentations. PubMed: Studies on the mechanism of the antimicrobial action of oleuropein.