bromoduline

CAS: 37339-90-5 C42 H72 O36 MW: 1153.00704000

Identification

Namelentinan
CAS Number37339-90-5
FDA UNII6751655D1D
Molecular FormulaC42 H72 O36
Molecular Weight1153.00704000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 1471.97 °C. @ 760.00 mm Hg (est)
Flash Point 1551.00 °F. TCC ( 844.00 °C. ) (est)
logP (o/w) -12.265 (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintravenous-dog LD50 > 100 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 > 2500 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for lentinan usage levels up tonot for fragrance use.
Recommendation for lentinan flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

lentinula edodes PMC

Synonyms

bromoduline PubMed: Lentinan degradation in the Lentinula edodes fruiting body during postharvest preservation is reduced by downregulation of the exo-β-1,3-glucanase EXG2. PubMed: Shiitake dermatitis recorded by French Poison Control Centers - new case series with clinical observations. PubMed: Inhibition of aflatoxin synthesis in Aspergillus flavus by three structurally modified lentinans. PubMed: Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds. PubMed: Shiitake dermatitis: a distinctive clinical entity. PubMed: Clinical variability of shiitake dermatitis. PubMed: Antitumor activity of mushroom polysaccharides: a review. PubMed: Dynamic high pressure microfluidization-assisted extraction and antioxidant activities of lentinan. PubMed: β-Glucans are involved in immune-modulation of THP-1 macrophages. PubMed: [Pregnant woman with flagellate erythema]. PubMed: [Shiitake dermatitis now occurs in France]. PubMed: [Provision for adverse effect of S-1 containing chemotherapy in patients with advanced digestive cancer--combination with superfine dispersed lentinan]. PubMed: Effects of management factors on the concentration of a high molecular weight polysaccharide fraction from log-grown shiitake mushrooms (Lentinula edodes (Berk.) Pegler). PubMed: Beta-glucans in higher fungi and their health effects. PubMed: Different suppressive effects of fucoidan and lentinan on IL-8 mRNA expression in in vitro gut inflammation. PubMed: Clinical efficacy of superfine dispersed lentinan (beta-1,3-glucan) in patients with hepatocellular carcinoma. PubMed: Structural characterization, chain conformation, and morphology of a beta-(1-->3)-D-glucan isolated from the fruiting body of Dictyophora indusiata. PubMed: [Effects of six polysaccharides extracted from plants on the immunological cells of mice]. PubMed: Immunological effects of yeast- and mushroom-derived beta-glucans. PubMed: [Anti tumor activities of lentinan and micellapist in tumor-bearing mice]. PubMed: Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver. PubMed: 1,3-beta-glucan quantification by a fluorescence microassay and analysis of its distribution in foods. PubMed: Effects of management on the yield and high-molecular-weight polysaccharide content of shiitake (Lentinula edodes) mushrooms. PubMed: Anti-tumor polysaccharides from mushrooms during storage. PubMed: Autolysis of lentinan, an antitumor polysaccharide, during storage of Lentinus edodes, shiitake mushroom. PubMed: Effects of lentinan on abnormal ingestive behaviors induced by tumor necrosis factor. PubMed: Effect of a nitrofuran derivative (AF2) on the immune response of mice.