lentinan
bromoduline
Identification
| Name | lentinan |
| CAS Number | 37339-90-5 |
| FDA UNII | 6751655D1D |
| Molecular Formula | C42 H72 O36 |
| Molecular Weight | 1153.00704000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 1471.97 °C. @ 760.00 mm Hg (est) |
| Flash Point | 1551.00 °F. TCC ( 844.00 °C. ) (est) |
| logP (o/w) | -12.265 (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-dog LD50 > 100 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 > 2500 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for lentinan usage levels up to | not for fragrance use. |
| Recommendation for lentinan flavor usage levels up to | not for flavor use. |
BOC Sciences
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Glentham Life Sciences Ltd
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Potential Uses
Natural Occurrence
Synonyms
bromoduline
PubMed:
Lentinan degradation in the Lentinula edodes fruiting body during postharvest preservation is reduced by downregulation of the exo-β-1,3-glucanase EXG2.
PubMed:
Shiitake dermatitis recorded by French Poison Control Centers - new case series with clinical observations.
PubMed:
Inhibition of aflatoxin synthesis in Aspergillus flavus by three structurally modified lentinans.
PubMed:
Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds.
PubMed:
Shiitake dermatitis: a distinctive clinical entity.
PubMed:
Clinical variability of shiitake dermatitis.
PubMed:
Antitumor activity of mushroom polysaccharides: a review.
PubMed:
Dynamic high pressure microfluidization-assisted extraction and antioxidant activities of lentinan.
PubMed:
β-Glucans are involved in immune-modulation of THP-1 macrophages.
PubMed:
[Pregnant woman with flagellate erythema].
PubMed:
[Shiitake dermatitis now occurs in France].
PubMed:
[Provision for adverse effect of S-1 containing chemotherapy in patients with advanced digestive cancer--combination with superfine dispersed lentinan].
PubMed:
Effects of management factors on the concentration of a high molecular weight polysaccharide fraction from log-grown shiitake mushrooms (Lentinula edodes (Berk.) Pegler).
PubMed:
Beta-glucans in higher fungi and their health effects.
PubMed:
Different suppressive effects of fucoidan and lentinan on IL-8 mRNA expression in in vitro gut inflammation.
PubMed:
Clinical efficacy of superfine dispersed lentinan (beta-1,3-glucan) in patients with hepatocellular carcinoma.
PubMed:
Structural characterization, chain conformation, and morphology of a beta-(1-->3)-D-glucan isolated from the fruiting body of Dictyophora indusiata.
PubMed:
[Effects of six polysaccharides extracted from plants on the immunological cells of mice].
PubMed:
Immunological effects of yeast- and mushroom-derived beta-glucans.
PubMed:
[Anti tumor activities of lentinan and micellapist in tumor-bearing mice].
PubMed:
Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver.
PubMed:
1,3-beta-glucan quantification by a fluorescence microassay and analysis of its distribution in foods.
PubMed:
Effects of management on the yield and high-molecular-weight polysaccharide content of shiitake (Lentinula edodes) mushrooms.
PubMed:
Anti-tumor polysaccharides from mushrooms during storage.
PubMed:
Autolysis of lentinan, an antitumor polysaccharide, during storage of Lentinus edodes, shiitake mushroom.
PubMed:
Effects of lentinan on abnormal ingestive behaviors induced by tumor necrosis factor.
PubMed:
Effect of a nitrofuran derivative (AF2) on the immune response of mice.