notoginsenoside R1

O- acetylseudolaric acid C beta-d- glucopyranoside, (3beta,6alpha,12beta)-20-(beta-d-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-beta-D-xylopyranosyl- (-)-pseudo laric acid B pseudo laric acid B PubMed: Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). PubMed: New triterpenoid saponins from fruits specimens of Panax japonicus collected in Kumamoto and Miyazaki prefectures (1). PubMed: [Influence of particle sizes and content of effective compositions of Panax notoginseng powders crashing by superfine somminution technique]. PubMed: Notoginsenoside R1 attenuates hypoxia and hypercapnia-induced vasoconstriction in isolated rat pulmonary arterial rings by reducing the expression of ERK. PubMed: Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. PubMed: Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model. PubMed: Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network. PubMed: [Major hypoglycemic ingredients of panax notoginseng saponins for treating diabetes]. PubMed: Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways. PubMed: Preparation of a monoclonal antibody against notoginsenoside R1, a distinctive saponin from Panax notoginseng, and its application to indirect competitive ELISA. PubMed: [Chemical constituents from processed rhizomes of Panax notoginseng]. PubMed: On-line coupling of macroporous resin column chromatography with direct analysis in real time mass spectrometry utilizing a surface flowing mode sample holder. PubMed: Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: a novel mechanism of Nrf2/ARE signaling activation. PubMed: [Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province]. PubMed: [Simultaneous content determination of notoginsenoside R1, ginsenoside Rg1, Re, Rb1 and dracorhodin in ZJHX rubber paste by double wavelength HPLC]. PubMed: Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography. PubMed: Protective effects of Notoginsenoside R1 on intestinal ischemia-reperfusion injury in rats. PubMed: Influence of gastrointestinal digestion and edible plant combination on oral bioavailability of triterpene saponins, using a biomimetic digestion and absorption system and determination by HPLC. PubMed: A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food. PubMed: Components of Panax notoginseng saponins enhance the cytotoxicity of cisplatin via their effects on gap junctions. PubMed: Effects of Borneol on Pharmacokinetics and Tissue Distribution of Notoginsenoside R1 and Ginsenosides Rg1 and Re in Panax notoginseng in Rabbits. PubMed: Combinatorial metabolism notably affects human systemic exposure to ginsenosides from orally administered extract of Panax notoginseng roots (Sanqi). PubMed: [Systematic study on QAMS method for quality control of Panax notoginseng]. PubMed: Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). PubMed: Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into oestrogen receptor activation and PI3K/Akt signalling. PubMed: [Effects of the combination of active component extracts from Astragalus membranaceus and Panax notoginseng on apoptosis, reactive oxygen species and mitochondrial membrane potential of PC12 cells with oxidative injury]. PubMed: [Analysis of saponins in Panax notoginseng by UPLC-LTQ-Orbitrap MS/MS]. PubMed: Core-shell hybrid liposomal vesicles loaded with panax notoginsenoside: preparation, characterization and protective effects on global cerebral ischemia/reperfusion injury and acute myocardial ischemia in rats. PubMed: The effects of notoginsenoside R₁ on the intestinal absorption of geniposide by the everted rat gut sac model. PubMed: Analysis of Panax notoginseng metabolites in rat bile by liquid chromatography-quadrupole time-of-flight mass spectrometry with microdialysis sampling. PubMed: New triterpenoid saponins from fruits specimens of Panax japonicus collected in Kumamoto and Miyazaki prefectures (1). PubMed: Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen. PubMed: [Network pharmacology study on major active compounds of Fufang Danshen formula]. PubMed: Metabolite profiling and pharmacokinetics of herbal compounds following oral administration of a cardiovascular multi-herb medicine (Qishen yiqi pills) in rats. PubMed: [Study on methodology of determination of Yizhi osmotic pump tablets active ingredient in Beagle dog plasma by LC-MS/MS]. PubMed: Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins. PubMed: [Effects of combination of Salvia miltiorrhiza and Panax notoginseng on the pharmacokinetics of their major bioactive components in Beagle dog]. PubMed: [In vitro balanced sustained-release of Panax notoginseng saponins controlled with various matrix materials]. PubMed: Displacement of bilirubin from albumin in plasma from jaundiced newborns. An in vitro study of purified Chinese herbal constituents and sulfisoxazole. PubMed: [Study on preparation and quality standard of Xueshuantong Drop Pills]. PubMed: Metabolism study of notoginsenoside r1, ginsenoside rg1 and ginsenoside rb1 of radix panax notoginseng in zebrafish. PubMed: Simultaneous determination of three Panax notoginseng saponins at sub-nanograms by LC-MS/MS in dog plasma for pharmacokinetics of compound Danshen tablets. PubMed: Anti-diabetic effects of Panax notoginseng saponins and its major anti-hyperglycemic components. PubMed: [Determination of effective components in different positions of Panax notoginseng by HPLC]. PubMed: Characterization of metabolism and in vitro permeability study of notoginsenoside R1 from Radix notoginseng. PubMed: Simultaneous determination of three major bioactive saponins of Panax notoginseng using liquid chromatography-tandem mass spectrometry and a pharmacokinetic study. PubMed: Notoginsenoside R1 attenuates renal ischemia-reperfusion injury in rats. PubMed: [HPLC-CAD in optimizating of saponins extraction from Radix et Rhizoma Notoginseng]. PubMed: [Study on preparation and release mechanism of effervescent osmotic pump tablet of compound Danshen]. PubMed: Simultaneous determination of notoginsenoside R1, ginsenoside Rg1, Re, Rb1 and icariin in rat plasma by ultra-performance liquid chromatography-tandem mass spectrometry. PubMed: [Preparation and release characterization in vitro of pulsed-release tablets of compound Danshen]. PubMed: Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly. PubMed: Antiproliferative effects of different plant parts of Panax notoginseng on SW480 human colorectal cancer cells. PubMed: Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography. PubMed: [Studies on chemical constituents from rhizomes of Panax notoginseng]. PubMed: Effect of notoginsenoside R1 on hepatic microcirculation disturbance induced by gut ischemia and reperfusion. PubMed: Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells. PubMed: Protective effects of ginsenoside Rb1, ginsenoside Rg1, and notoginsenoside R1 on lipopolysaccharide-induced microcirculatory disturbance in rat mesentery. PubMed: [Effect compound decoction on notoginsenosides in Panax notoginseng]. PubMed: Microbial transformation of 20(S)-protopanaxatriol-type saponins by Absidia coerulea. PubMed: Chemical characteristics of three medicinal plants of the Panax genus determined by HPLC-ELSD. PubMed: A rapid method for the simultaneous determination of 11 saponins in Panax notoginseng using ultra performance liquid chromatography. PubMed: Pharmacokinetic and absolute bioavailability study of total panax notoginsenoside, a typical multiple constituent traditional chinese medicine (TCM) in rats. PubMed: Application of atmospheric pressure chemical ionisation mass spectrometry in the identification and differentiation of Panax species. PubMed: Simultaneous determination of panax notoginsenoside R1, ginsenoside Rg1, Rd, Re and Rb1 in rat plasma by HPLC/ESI/MS: platform for the pharmacokinetic evaluation of total panax notoginsenoside, a typical kind of multiple constituent traditional Chinese medicine. PubMed: [RP-HPLC characteristics of Panax notoginseng]. PubMed: Ginsenoside Re and notoginsenoside R1: Immunologic adjuvants with low haemolytic effect. PubMed: Simultaneous determination of 11 saponins in Panax notoginseng using HPLC-ELSD and pressurized liquid extraction. PubMed: [Determination of notoginsenoside R1 and ginsenoside Rg1 in Rupixiao tablets by HPLC]. PubMed: Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway. PubMed: Simultaneous determination of components in preparation Naodesheng injection by high performance liquid chromatograph-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI). PubMed: Chemical characteristics for different parts of Panax notoginseng using pressurized liquid extraction and HPLC-ELSD. PubMed: Notoginsenoside R1 from Panax notoginseng inhibits TNF-alpha-induced PAI-1 production in human aortic smooth muscle cells. PubMed: A rapid HPLC-ESI-MS/MS for qualitative and quantitative analysis of saponins in "XUESETONG" injection. PubMed: Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction. PubMed: Determination of four active saponins of Panax notoginseng in rat feces by high-performance liquid chromatography. PubMed: Orthogonal array design in optimizing the extraction efficiency of active constituents from roots of Panax notoginseng. PubMed: [Cell proliferation inhibitive and apoptosis promoting effects of sanchi extract on GES-1 cell after being transformed by MNNG]. PubMed: [Effects of panax notoginseng saponins on the process of renal interstitial fibrosis after unilateral ureteral obstruction in rats]. PubMed: Simultaneous quantification of six major active saponins of Panax notoginseng by high-performance liquid chromatography-UV method. PubMed: [Determination of notoginsenoside R1, ginsenoside Rg1 and Rb1 in Radix Notoginseng and its preparation by HPLC-ELSD]. PubMed: HPLC determination of four active saponins from Panax notoginseng in rat serum and its application to pharmacokinetic studies. PubMed: Liquid chromatographic method for determination of four active saponins from Panax notoginseng in rat urine using solid-phase extraction. PubMed: [Identification of Panax notoginseng and its preparations by LC/MS]. PubMed: [Up-regulation of transcription factors NF-E2, c-jun and c-fos of AP-1 family induced by Panax Notoginosides in hematopoietic cells]. PubMed: [Effects of root rot on saponin content in Panax notoginseng]. PubMed: Chemical assessment of roots of Panax notoginseng in China: regional and seasonal variations in its active constituents. PubMed: [Effect of Panax notoginsenosides on the proliferation of hematopoietic progenitor cells in mice with immune-mediated aplastic anemia]. PubMed: Analysis of saponins in raw and steamed Panax notoginseng using high-performance liquid chromatography with diode array detection. PubMed: Isolation of dammarane saponins from Panax notoginseng by high-speed counter-current chromatography. PubMed: [Proliferation and differentiation of human CD34+ hematopoietic stem/progenitor cells induced by Panax notoginosides]. PubMed: Notoginseny cream in the treatment of phlebitis. PubMed: [Determination of notoginsenoside R1 in radix notoginseng by HPLC-ELSD]. PubMed: Bioactive saponins and glycosides. XIX. Notoginseng (3): immunological adjuvant activity of notoginsenosides and related saponins: structures of notoginsenosides-L, -M, and -N from the roots of Panax notoginseng (Burk.) F. H. Chen. PubMed: Saponins of plants of Panax species collected in Central Nepal, and their chemotaxonomical significance. III. PubMed: Effect of notoginsenoside R1 on the synthesis of components of the fibrinolytic system in cultured smooth muscle cells of human pulmonary artery. PubMed: Notoginsenoside R1 counteracts endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo. PubMed: Effect of notoginsenoside R1 on the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells. PubMed: [Protection of Chinese medicinal herb extracts against cerebral ischemia-reperfusion injury]. PubMed: [Preliminary studies of notoginsenoside R1-induced differentiation of HL-60 cell lines in vitro].