breviscapine

breviscapin (2S,3S,4S,5R,6S)-6-[5,6- dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid scutellarein 7-b-D-glucuronide scutellarin viminol R2 PubMed: [Evaluation of transdermal property in vitro of different breviscapine lipid carrier gels]. PubMed: [Study on the extraction of breviscapine from Erigeron breviscapus with ultrasonic wave technology optimized by central composite design-response surface method]. PubMed: Improved oral bioavailability of breviscapine via a Pluronic P85-modified liposomal delivery system. PubMed: Mixed polyethylene glycol-modified breviscapine-loaded solid lipid nanoparticles for improved brain bioavailability: preparation, characterization, and in vivo cerebral microdialysis evaluation in adult Sprague Dawley rats. PubMed: Progress on the protective effect of compounds from natural medicines on cerebral ischemia. PubMed: Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats. PubMed: Breviscapine reduces acute lung injury induced by left heart ischemic reperfusion in rats by inhibiting the expression of ICAM-1 and IL-18. PubMed: Solid dispersion tablets of breviscapine with polyvinylpyrrolidone K30 for improved dissolution and bioavailability to commercial breviscapine tablets in beagle dogs. PubMed: Pharmacokinetic interaction between scutellarin and valsartan in rats. PubMed: Development of ionic-complex-based nanostructured lipid carriers to improve the pharmacokinetic profiles of breviscapine. PubMed: Superior renoprotective effects of the combination of breviscapine with enalapril and its mechanism in diabetic rats. PubMed: [Evaluation of transdermal property in vitro of different breviscapine lipid carrier gels]. PubMed: [Protective effect of breviscapine on human hepatocytes under hypoxia/re-oxygenation and its possible mechanism]. PubMed: Lipid emulsion as a drug delivery system for breviscapine: formulation development and optimization. PubMed: UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats. PubMed: Breviscapine inhibits high glucose-induced proliferation and migration of cultured vascular smooth muscle cells of rats via suppressing the ERK1/2 MAPK signaling pathway. PubMed: Effects of breviscapine on pulmonary inflammatory response and lung injury in children undergoing open heart surgery. PubMed: [Intestinal lymphatic transport of breviscapine orally administered in rat]. PubMed: Metabolic transformation of DMBA-induced carcinogenesis and inhibitory effect of salvianolic acid b and breviscapine treatment. PubMed: Preparation, characterization and evaluation of breviscapine lipid emulsions coated with monooleate-PEG-COOH. PubMed: [The anti-injury effect of breviscapine injection on the hypoxic ischemic brain damage of neonatal rats and the expression of Bcl-2 and Bax]. PubMed: [Study on the extraction of breviscapine from Erigeron breviscapus with ultrasonic wave technology optimized by central composite design-response surface method]. PubMed: Optimized preparation, characterization and biodistribution in heart of breviscapine lipid emulsion. PubMed: Characterization, biodistribution and targeting evaluation of breviscapine lipid emulsions following intravenous injection in mice. PubMed: [Formula screening and optimizing for the dispersible tablets of breviscapine by orthogonal experiment]. PubMed: [Protective effect of breviscapine on cardiac function in children after cardiopulmonary bypass undergoing open heart surgery]. PubMed: [Protective effects of Fufangdengzhanhua dripping pill on apoptosis induced by glutamate in cultured primary hippocampal neurons of rats]. PubMed: [Advances in studies on pharmacokinetics of scutellarin and scutellarein]. PubMed: Breviscapine protects against cardiac hypertrophy through blocking PKC-alpha-dependent signaling. PubMed: Breviscapine-induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity. PubMed: Breviscapine ameliorates cardiac dysfunction and regulates the myocardial Ca(2+)-cycling proteins in streptozotocin-induced diabetic rats. PubMed: Breviscapine improves functions of spatial learning and memory of focal cerebral ischemia rats. PubMed: [Study on physicochemical properties and influence factors on stability of breviscapine]. PubMed: [Comparison of the distribution of breviscapine in the brain by different administration routes]. PubMed: Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway. PubMed: Preparation, characterization, and biodistribution of breviscapine proliposomes in heart. PubMed: [The effect of polyamidoamine (PAMAM) dendrimers on the solubility and pharmacokinetics of breviscapine]. PubMed: [Effects of Dengzhan Xixin on blood-brain barrier permeability and metabolites after cerebral ischemia-reperfusion injuries]. PubMed: [Effects of in vitro conditions on release behavior of different types of sustained and controlled release formulations of breviscapin]. PubMed: Breviscapine, a traditional Chinese medicine, alleviates myocardial ischaemia reperfusion injury in diabetic rats. PubMed: [The effect of breviscapine on the pulmonary arterial pressure and the expression of Rho-kinase in pulmonary arterioles of hypoxic rats]. PubMed: Studies on antioxidant activities of breviscapine in the cell-free system. PubMed: Dengzhanhua preparations for acute cerebral infarction. PubMed: Comparative pharmacokinetics of breviscapine liposomes in dogs, rabbits and rats. PubMed: Pharmacokinetics and biodistribution of surface modification polymeric nanoparticles. PubMed: Effect of ion-pairing and enhancers on scutellarin skin permeability. PubMed: Neuroprotective effects of breviscapine against apoptosis induced by transient focal cerebral ischaemia in rats. PubMed: Breviscapine alleviates hepatic injury and inhibits PKC-mRNA and its protein expression in brain-dead BA-Ma mini pigs. PubMed: [Effect of Erigeron Breviscapine on premaxillary suture distraction osteogenesis in rabbit]. PubMed: Protective effects of scutellarin and breviscapine on brain and heart ischemia in rats. PubMed: [Protective effects of breviscapine against cultured rat hippocampal neuronal toxicity induced by glutamate]. PubMed: Isolation and identification of ten metabolites of breviscapine in rat urine. PubMed: Prevention of early liver injury by breviscapine in streptozotocin-induced diabetic rats. PubMed: Two major urinary metabolites of scutellarin in rats. PubMed: Amelioration of graft ischemia-reperfusion injury by breviscapine in rat small bowel transplantation. PubMed: [Protective effects of Denghuang injection on cerebral infarction in animal]. PubMed: Effect of breviscapine on fractalkine expression in chronic hypoxic rats. PubMed: Protective effects of breviscapine on ischemic vascular dementia in rats. PubMed: Renoprotective effect of breviscapine through suppression of renal macrophage recruitment in streptozotocin-induced diabetic rats. PubMed: [How brain-dead state affects the hepatic morphology and function of Ba-Ma mini pigs and its mechanism]. PubMed: [Pharmacokinetics of breviscapine liposomes following intravenous injection in Beagle dogs]. PubMed: Preparation and pharmacokinetics in rabbits of breviscapine unilamellar vesicles. PubMed: [Pharmacokinetics of breviscapine in dogs and rabbits following single intravenous administration]. PubMed: Distribution of liposomal breviscapine in brain following intravenous injection in rats. PubMed: Pharmacokinetics of scutellarin and its aglycone conjugated metabolites in rats. PubMed: Determination of aglycone conjugated metabolites of scutellarin in rat plasma by HPLC. PubMed: [Pharmacokinetics of breviscapine and its beta-cyclodextrin complex in rats]. PubMed: Multivesicular liposome formulation for the sustained delivery of breviscapine. PubMed: Enhanced oral bioavailability of breviscapine after encapsulation in a liposomal formulation. PubMed: Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment. PubMed: [Enhanced absorption of breviscapine photosomes in small intestine of rats]. PubMed: [Determination of entrapment efficiency of breviscapine nanoliposomes]. PubMed: [Regulation of pre-mRNA alternative spicing in U251 cells by TPA]. PubMed: A study of the cardioprotective effect of breviscapine during hypoxia of cardiomyocytes. PubMed: Study on pharmacokinetics of scutellarin in rabbits. PubMed: [Pharmacokinetics of scutellarin in rabbits]. PubMed: [Effect of breviscapine on urinary micro-albumine in patients with diabetes mellitus type 2]. PubMed: [Regulation of the expression of pulmonary arterial collagen by protein kinase C and breviscapine in chronic hypoxic rats]. PubMed: Differential effects of new breviscapine on arachidonic acid metabolisms in blood cells and endothelial cells. PubMed: Effect of new-breviscapine on fibrinolysis and anticoagulation of human vascular endothelial cells. PubMed: [An experimental study on the anti-reoxidation injury on myocardium of Erigeron breviscapus].