hypericin

cyclosan

CAS: 548-04-9 C30 H16 O8 MW: 504.45112000

Identification

Namehypericin
CAS Number548-04-9
EINECS208-941-0
FDA UNII7V2F1075HD
Molecular FormulaC30 H16 O8
Molecular Weight504.45112000
MDL NumberMFCD00016683
Nikkaji NumberJ6.443B
Beilstein1917913

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 1020.33 °C. @ 760.00 mm Hg (est)
Flash Point 1084.00 °F. TCC ( 584.60 °C. ) (est)
logP (o/w) 10.827 (est)
Soluble in water, 6.262e-006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for hypericin usage levels up tonot for fragrance use.
Recommendation for hypericin flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Potential Uses

None Found

Natural Occurrence

st. john's wort

Synonyms

cyclo werrol cyclo-werol cyclosan 1,3,4,6,8,13- hexahydroxy-10,11-dimethyl-phenanthro[1,10,9,8-opqra]perylene-7,14-dione 1,3,4,6,8,13- hexahydroxy-10,11-dimethylphenanthro(1,10,9,8-opqra)perylene-7,14-dione 1,3,4,6,8,13- hexahydroxy-10,11-diméthylphénanthro[1,10,9,8-opqra]pérylène-7,14-dione 4,5,7,4',5',7'- hexahydroxy-2,2'-dimethyl-mesonapthtodianthron 4,4',5,5',7,7'- hexahydroxy-2,2'-dimethylnaphthodianthrone 4,5,7,4',5',7'- hexahydroxy-2,2'-dimethylnaphthodianthrone hypericine hypericum red phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10,11-dimethyl- vimrxyn PubMed: St. John's wort reversal of meningeal nociception: A natural therapeutic perspective for migraine pain. PubMed: Do Other Hypericum Species Have Medical Potential As St. John's Wort (Hypericum perforatum)? PubMed: [Chemical constituents from Hypericum perforatum]. PubMed: Pilot-scale culture of hypericum perforatum L. Adventitious roots in airlift bioreactors for the production of bioactive compounds. PubMed: Molecularly imprinted polymer for specific extraction of hypericin from Hypericum perforatum L. herbal extract. PubMed: Improvement of hairy root cultures and plants by changing biosynthetic pathways leading to pharmaceutical metabolites: Strategies and applications. PubMed: Assessment of antimicrobial and antiprotozoal activity of the olive oil macerate samples of Hypericum perforatum and their LC-DAD-MS analyses. PubMed: Between species diversity of Hypericum perforatum and H. maculatum by the content of bioactive compounds. PubMed: Effective inactivation of food pathogens Listeria monocytogenes and Salmonella enterica by combined treatment of hypericin-based photosensitization and high power pulsed light. PubMed: Plant-derived bioactive compounds produced by endophytic fungi. PubMed: Effect of St. John's Wort standardized extract and hypericin on in vitro placental calcium transport. PubMed: Determination of enantiomerization barriers of hypericin and pseudohypericin by dynamic high-performance liquid chromatography on immobilized polysaccharide-type chiral stationary phases and off-column racemization experiments. PubMed: Identification of human intracellular targets of the medicinal Herb St. John's Wort by chemical-genetic profiling in yeast. PubMed: Bioactive constituent production in St. John's Wort in vitro hairy roots. Regenerated plant lines. PubMed: Hypericin and hyperforin production in St. John's wort in vitro culture: influence of saccharose, polyethylene glycol, methyl jasmonate, and Agrobacterium tumefaciens. PubMed: Evaluation of the light-sensitive cytotoxicity of Hypericum perforatum extracts, fractions, and pure compounds. PubMed: Comparison of methods for the exhaustive extraction of hypericins, flavonoids, and hyperforin from Hypericum perforatum L. PubMed: Approach to novel functional foods for stress control 4. Regulation of serotonin transporter by food factors. PubMed: Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infection. PubMed: The significance of "nonsignificance" in randomized controlled studies: a discussion inspired by a double-blinded study on St. John's wort (Hypericum perforatum L.) for premenstrual symptoms. PubMed: Liquid chromatographic determination of St. John's wort components in functional foods. PubMed: Instability of St. John's wort (Hypericum perforatum L.) and degradation of hyperforin in aqueous solutions and functional beverage. PubMed: Clinic at the health food store? Employee recommendations and product analysis. PubMed: Determination of St. John's wort components in dietary supplements and functional foods by liquid chromatography. PubMed: Impact of hypericum (St.-John's-wort) given prenatally on cognition of mice offspring. PubMed: Inhibition of c-erbB-2 expression an activity in human ovarian carcinoma cells by hypericin. PubMed: Effects of a methanolic extract and a hyperforin-enriched CO2 extract of Hypericum perforatum on alcohol intake in rats. PubMed: Optimization of extraction conditions for active components in Hypericum perforatum using response surface methodology. PubMed: Effects of Hypericum perforatum extraction on alcohol intake in Marchigian Sardinian alcohol-preferring rats. PubMed: Toxins in chrysomelid beetles Possible evolutionary sequence from de novo synthesis to derivation from food-plant chemicals.