vitexin
8-D-glucosyl-4',5,7-trihydroxyflavone
Identification
| Name | vitexin |
| CAS Number | 3681-93-4 |
| EINECS | 222-963-8 |
| FDA UNII | 9VP70K75OK |
| Molecular Formula | C21 H20 O10 |
| Molecular Weight | 432.38240000 |
| MDL Number | MFCD00017456 |
| Nikkaji Number | J14.961F |
| Beilstein | 0067796 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 767.70 °C. @ 760.00 mm Hg (est) |
| Flash Point | 524.00 °F. TCC ( 273.10 °C. ) (est) |
| logP (o/w) | -0.014 (est) |
| Soluble in | water, 3919 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD25 1 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for vitexin usage levels up to | not for fragrance use. |
| Recommendation for vitexin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(1S)-1,5-
anhydro-1-[5,7-dihydroxy-2-(4-hydroxyphényl)-4-oxo-4H-chromén-8-yl]-D-glucitol
apigenin-8-C-glucoside
5,7-
dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
5,7-
dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-one
D-
glucitol, 1,5-anhydro-1-C-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-8-yl]-, (1S)-
8-b-D-
glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
8-b-D-
glucopyranosyl-apigenin
8-D-
glucosyl-4',5,7-trihydroxyflavone
PubMed:
[Chemical constituents of Rabdosia japonica var. glaucocalyx and their anti-complementary activity].
PubMed:
Flavone C-glycosides from the flowers of Trollius chinensis and their anti-complementary activity.
PubMed:
Antinociceptive, anti-inflammatory and antioxidant activities of aqueous extract from Remirea maritima (Cyperaceae).
PubMed:
Isolation of antithrombotic phenolic compounds from the leaves of Crataegus pinnatifida.
PubMed:
Chemical profile and antiacetylcholinesterase, antityrosinase, antioxidant and α-glucosidase inhibitory activity of Cynometra cauliflora L. leaves.
PubMed:
Four Flavonoid Compounds from Phyllostachys edulis Leaf Extract Retard the Digestion of Starch and Its Working Mechanisms.
PubMed:
Effects of antioxidants of bamboo leaves and flavonoids on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) formation in chemical model systems.
PubMed:
Verification of presence of caprolactam in sprouted achenes of Fagopyrum esculentum Moench and its influence on plant phenolic compound content.
PubMed:
Changes in phenols contents from buckwheat sprouts during growth stage.
PubMed:
Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin.
PubMed:
Metabolomic analysis of the polyphenols in germinating mung beans (Vigna radiata) seeds and sprouts.
PubMed:
Qualitative and quantitative analysis of phenolics in Tetrastigma hemsleyanum and their antioxidant and antiproliferative activities.
PubMed:
Variation in contents of main active components and antioxidant activity in leaves of different pigeon pea cultivars during growth.
PubMed:
Altitudinal variation of antioxidant components and capability in Indocalamus latifolius (Keng) McClure leaf.
PubMed:
Characterisation of different digestion susceptibility of lupin seed globulins.
PubMed:
Passiflora manicata (Juss.) aqueous leaf extract protects against reactive oxygen species and protein glycation in vitro and ex vivo models.
PubMed:
Caecal absorption of vitexin-2-O-xyloside and its aglycone apigenin, in the rat.
PubMed:
Genotoxicity and acute and subchronic toxicity studies of a standardized methanolic extract of Ficus deltoidea leaves.
PubMed:
Enrichment and antioxidant properties of flavone C-glycosides from trollflowers using macroporous resin.
PubMed:
Nutritional and functional potential of Beta vulgaris cicla and rubra.
PubMed:
An enzyme-linked immunosorbent assay for the measurement of plasma flavonoids in mice fed apigenin-C-glycoside.
PubMed:
Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells.
PubMed:
[Determination of plasma protein binding rate of vitexin].
PubMed:
Identification of the flavonoids in mungbean (Phaseolus radiatus L.) soup and their antioxidant activities.
PubMed:
Screening and quantitative analysis of antioxidants in the fruits of Livistona chinensis R. Br using HPLC-DAD-ESI/MS coupled with pre-column DPPH assay.
PubMed:
Effect of salinity stress on phenolic compounds and carotenoids in buckwheat (Fagopyrum esculentum M.) sprout.
PubMed:
Variation in phenolic content and antioxidant activity of fermented rooibos herbal tea infusions: role of production season and quality grade.
PubMed:
Assessment of flavonoids contents and in vitro antioxidant activity of Launaea procumbens.
PubMed:
A review of the chemistry of the genus Crataegus.
PubMed:
Accumulation of phenylpropanoids and correlated gene expression during the development of tartary buckwheat sprouts.
PubMed:
Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazole-induced seizure in rats.
PubMed:
An in vitro perspective to cholinesterase inhibitory and antioxidant activity of five Gentiana species and Gentianella caucasea.
PubMed:
Seasonal Variations of the Antioxidant Composition in Ground Bamboo Sasa argenteastriatus Leaves.
PubMed:
Antioxidants of therapeutic relevance in COPD from the neotropical blueberry Anthopterus wardii.
PubMed:
Mushroom tyrosinase inhibitors from mung bean (Vigna radiatae L.) extracts.
PubMed:
Vitexin protects against myocardial ischemia/reperfusion injury in Langendorff-perfused rat hearts by attenuating inflammatory response and apoptosis.
PubMed:
Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat.
PubMed:
Antioxidant properties of the mung bean flavonoids on alleviating heat stress.
PubMed:
Distribution of free amino acids, flavonoids, total phenolics, and antioxidative activities of Jujube (Ziziphus jujuba) fruits and seeds harvested from plants grown in Korea.
PubMed:
Metabolomic analysis of phenolic compounds in buckwheat (Fagopyrum esculentum M.) sprouts treated with methyl jasmonate.
PubMed:
Edible neotropical blueberries: antioxidant and compositional fingerprint analysis.
PubMed:
Topical and systemic anti-inflammatory effects of Echinodorus macrophyllus (Kunth) Micheli (Alismataceae).
PubMed:
The compound isolated from the leaves of Phyllostachys nigra protects oxidative stress-induced retinal ganglion cells death.
PubMed:
Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
PubMed:
Antioxidant activity of the dihydrochalcones Aspalathin and Nothofagin and their corresponding flavones in relation to other Rooibos ( Aspalathus linearis ) Flavonoids, Epigallocatechin Gallate, and Trolox.
PubMed:
Quantitation of chafurosides A and B in tea leaves and isolation of prechafurosides A and B from oolong tea leaves.
PubMed:
Investigation of contribution of individual constituents to antioxidant activity in herbal drugs using postcolumn HPLC method.
PubMed:
Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves.
PubMed:
Antioxidant constituents in the dayflower (Commelina communis L.) and their alpha-glucosidase-inhibitory activity.
PubMed:
Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by Fluorescence in situ hybridization (FISH).
PubMed:
HPLC-PDA-MS and NMR characterization of C-glycosyl flavones in a hydroalcoholic extract of Citrus aurantifolia leaves with antiplatelet activity.
PubMed:
Use of cyclic voltammetry, photochemiluminescence, and spectrophotometric methods for the measurement of the antioxidant capacity of buckwheat sprouts.
PubMed:
Trace element water improves the antioxidant activity of buckwheat (Fagopyrum esculentum Moench) sprouts.
PubMed:
Exudation of allelopathic substances in buckwheat (Fagopyrum esculentum Moench).
PubMed:
Metabolism of flavone C-glucosides and p-coumaric acid from antioxidant of bamboo leaves (AOB) in rats.
PubMed:
Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells.
PubMed:
Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum.
PubMed:
Determination of flavone C-glucosides in antioxidant of bamboo leaves (AOB) fortified foods by reversed-phase high-performance liquid chromatography with ultraviolet diode array detection.
PubMed:
Unfermented rooibos tea: quantitative characterization of flavonoids by HPLC-UV and determination of the total antioxidant activity.
PubMed:
Phenolic constituents and antioxidant properties of Xanthosoma violaceum leaves.
PubMed:
Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (Hawthorn) subjected to drought and cold stress.
PubMed:
Thyroid ultrasound is the best prevalence indicator for assessment of iodine deficiency disorders: a study in rural/tribal schoolchildren from Gujarat (Western India).
PubMed:
Effect of processing on the flavonoid content in buckwheat (Fagopyrum esculentum Möench) grain.
PubMed:
Determination of flavone C-glycosides in tea.
PubMed:
Antithyroid and goitrogenic effects of millet: role of C-glycosylflavones.