plenolin
ambros-2-en-12-oic acid, 6-a,8-b-dihydroxy-4-oxo-, 12,8-lactone, (11S)-
Identification
| Name | plenolin |
| CAS Number | 34257-95-9 |
| FDA UNII | Search |
| Molecular Formula | C15 H20 O4 |
| Molecular Weight | 264.32120000 |
| XlogP3 | 0.50 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 451.44 °C. @ 760.00 mm Hg (est) |
| Flash Point | 337.00 °F. TCC ( 169.50 °C. ) (est) |
| logP (o/w) | 1.980 (est) |
| Soluble in | water, 2.245e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 31 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for plenolin usage levels up to | not for fragrance use. |
| Recommendation for plenolin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
ambros-2-en-12-oic acid, 6-a,8-b-dihydroxy-4-oxo-, 12,8-lactone, (11S)-
11,13-
dihydrohelenalin
11alpha,13-
dihydrohelenalin
(1S,3aR,5S,5aR,8aR,9S,9aS)-9-
hydroxy-1,5,8a-trimethyl-3a,4,5,5a,9,9a-hexahydro-1H-azuleno[6,7-b]furan-2,8-dione
PubMed:
Quantitative analysis of sesquiterpene lactones in extract of Arnica montana L. by 1H NMR spectroscopy.
PubMed:
Permeation of bioactive constituents from Arnica montana preparations through human skin in-vitro.
PubMed:
Development and stability of semisolid preparations based on a supercritical CO2 Arnica extract.
PubMed:
Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers.
PubMed:
Biologically active constituents of Centipeda minima: isolation of a new plenolin ester and the antiallergy activity of sesquiterpene lactones.