lithospermum erythrorhizon root oil CO2 extract

purple gromwell root oil CO2 extract

CAS: 223749-76-6

Identification

Namelithospermum erythrorhizon root oil CO2 extract
IUPAClithospermum erythrorhizon root oil CO2 extract
CAS Number223749-76-6
FDA UNIISearch

Regulatory

Physical Properties

Appearance dark red liquid (est)
Food Chemicals Codex Listed No

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for lithospermum erythrorhizon root oil CO2 extract usage levels up tonot for fragrance use.
Recommendation for lithospermum erythrorhizon root oil CO2 extract flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

gromwell purple gromwell root

Synonyms

purple gromwell root oil CO2 extract red-root gromwell root oil CO2 extract lithospermum officinale var. erythrorhizon root oil CO2 extract PubMed: Pharmacological properties of shikonin - a review of literature since 2002. PubMed: Topical herbal formulae in the management of psoriasis: systematic review with meta-analysis of clinical studies and investigation of the pharmacological actions of the main herbs. PubMed: Shikonin promotes intestinal wound healing in vitro via induction of TGF-β release in IEC-18 cells. PubMed: Traditional chinese medicine remedy to jury: the pharmacological basis for the use of shikonin as an anticancer therapy. PubMed: Shikonin, a natural product from the root of Lithospermum erythrorhizon, is a cytotoxic DNA-binding agent. PubMed: Beneficial effect of shikonin on experimental colitis induced by dextran sulfate sodium in BALB/c mice. PubMed: Shikonin attenuates lipopolysaccharide-induced acute lung injury in mice. PubMed: β,β-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells. PubMed: Novel multiple apoptotic mechanism of shikonin in human glioma cells. PubMed: Inhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo. PubMed: Dermocosmetics for dry skin: a new role for botanical extracts. PubMed: Tigloylshikonin, a new minor Shikonin derivative, from the roots and the commercial root extract of lithospermum erythrorhizon. PubMed: In vitro screening of tumoricidal properties of international medicinal herbs: part II. PubMed: Lithospermic acid derivatives from Lithospermum erythrorhizon increased expression of serine palmitoyltransferase in human HaCaT cells. PubMed: Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling. PubMed: Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-kappaB: neuroprotective implications. PubMed: Cosmetic formulations containing Lithospermum erythrorhizon root extract show moisturizing effects on human skin. PubMed: Lithospermi radix extract inhibits histamine release and production of inflammatory cytokine in mast cells. PubMed: Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. PubMed: Protection of human keratinocytes from UVB-induced inflammation using root extract of Lithospermum erythrorhizon. PubMed: Non-radioactive and colorimetric quantification of monocyte adhesion to endothelial cells in early atherogenesis. PubMed: Inhibition of lipopolysaccharide and interferon-gamma-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by Lithospermi radix in mouse peritoneal macrophages. PubMed: Caffeic acid metabolites from Eritrichium sericeum cell cultures. PubMed: Enhancement of natural pigment extraction using Bacillus species xylanase. PubMed: Inhibitory effect of the Agrobacterium rhizogenes rolC gene on rabdosiin and rosmarinic acid production in Eritrichium sericeum and Lithospermum erythrorhizon transformed cell cultures. PubMed: Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo. PubMed: Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. PubMed: High level expression of chorismate pyruvate-lyase (UbiC) and HMG-CoA reductase in hairy root cultures of Lithospermum erythrorhizon. PubMed: Cellular pharmacology studies of shikonin derivatives. PubMed: A novel dark-inducible protein, LeDI-2, and its involvement in root-specific secondary metabolism in Lithospermum erythrorhizon. PubMed: Reaction of beta-alkannin (shikonin) with reactive oxygen species: detection of beta-alkannin free radicals. PubMed: Genetic engineering on shikonin biosynthesis: expression of the bacterial ubiA gene in Lithospermum erythrorhizon. PubMed: Simultaneous analysis of shikimate-derived secondary metabolites in Lithospermum erythrorhizon cell suspension cultures by high-performance liquid chromatography. PubMed: Caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures. PubMed: Genetic engineering of shikonin biosynthesis hairy root cultures of Lithospermum erythrorhizon transformed with the bacterial ubiC gene. PubMed: Cell-specific production and antimicrobial activity of naphthoquinones in roots of lithospermum erythrorhizon PubMed: Shikonin, an ingredient of Lithospermum erythrorhizon, inhibits angiogenesis in vivo and in vitro. PubMed: cDNA cloning and gene expression of phenylalanine ammonia-lyase in Lithospermum erythrorhizon. PubMed: Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I. PubMed: Shikonin production by extractive cultivation in transformed-suspension and hairy root cultures of Lithospermum erythrorhizon. PubMed: [Screening test of crude drug extract on anti-HIV activity]. PubMed: Shikonin production and secretion by hairy root cultures of Lithospermum erythrorhizon. PubMed: Betanin Production and Release In Vitro from Suspension Cultures of Beta vulgaris.