cynara scolymus extract (whole plant)
extract of the whole plant, cynara scolymus
Identification
| Name | cynara scolymus extract (whole plant) |
| IUPAC | cynara scolymus extract |
| CAS Number | 84012-14-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 1000 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for cynara scolymus extract (whole plant) usage levels up to | not for fragrance use. |
| Recommendation for cynara scolymus extract (whole plant) flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
artichoke extract (whole plant)
artichoke extract HS 2564 G (Grau)
actipone
artichoke GW (Symrise)
extract of the whole plant, cynara scolymus
PubMed:
Use of artichoke (Cynara scolymus) flower extract as a substitute for bovine rennet in the manufacture of Gouda-type cheese: characterization of aspartic proteases.
PubMed:
Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells.
PubMed:
Investigation of the in vivo antioxidative activity of Cynara scolymus (artichoke) leaf extract in the streptozotocin-induced diabetic rat.
PubMed:
Lanthanide-IMAC enrichment of carbohydrates and polyols.
PubMed:
Cynara Scolymus Leaf Extract Stimulates Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Hepatic Glucose Output in H4IIE Hepatocytes.
PubMed:
Extensive characterisation of bioactive phenolic constituents from globe artichoke (Cynara scolymus L.) by HPLC-DAD-ESI-QTOF-MS.
PubMed:
Protective activity of Cynara scolymus L. leaf extract against chemically induced complex genomic alterations in CHO cells.
PubMed:
Protective effect of artichoke (Cynara scolymus) leaf extract against lead toxicity in rat.
PubMed:
Chemical constituents and anti-ulcerogenic potential of the scales of Cynara scolymus (artichoke) heads.
PubMed:
Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:
Metabolic management in overweight subjects with naive impaired fasting glycaemia by means of a highly standardized extract from Cynara scolymus: a double-blind, placebo-controlled, randomized clinical trial.
PubMed:
[Artichoke--untapped potential of herbal medicine in the treatment of atherosclerosis and liver diseases].
PubMed:
[Development and validation of method for the determination of cynarin, luteolin in plasma].
PubMed:
In vivo genotoxicity evaluation of an artichoke (Cynara scolymus L.) aqueous extract.
PubMed:
Artichoke induces genetic toxicity in the cytokinesis-block micronucleus (CBMN) cytome assay.
PubMed:
Separation and identification of phenolic compounds in canned artichoke by LC/DAD/ESI-MS using core-shell C18 column: a comparative study.
PubMed:
Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B.
PubMed:
Effect of zeolite nano-materials and artichoke (Cynara scolymus L.) leaf extract on increase in urinary clearance of systematically absorbed nicotine.
PubMed:
Development of an automated method for Folin-Ciocalteu total phenolic assay in artichoke extracts.
PubMed:
Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
PubMed:
Artichoke induces genetic toxicity and decreases ethyl methanesulfonate-related DNA damage in Chinese hamster ovary cells.
PubMed:
Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial.
PubMed:
Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on food intake and glycemia in rats.
PubMed:
Extracts of edible and medicinal plants in inhibition of growth, adherence, and cytotoxin production ofâCampylobacter jejuniâandâCampylobacter coli.
PubMed:
Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters.
PubMed:
Appetite Control and Glycaemia Reduction in Overweight Subjects treated with a Combination of Two Highly Standardized Extracts from Phaseolus vulgaris and Cynara scolymus.
PubMed:
Evidence of glycemia-lowering effect by a Cynara scolymus L. extract in normal and obese rats.
PubMed:
Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation.
PubMed:
Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells.
PubMed:
[Phytotherapy with a mixture of dry extracts with hepato-protective effects containing artichoke leaves in the management of functional dyspepsia symptoms].
PubMed:
Inhibitory effect of the flowers of artichoke (Cynara cardunculus) on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin.
PubMed:
Effects of artichoke leaf extract on acute gastric mucosal injury in rats.
PubMed:
The effect of artichoke (Cynara scolymus L.) extract on respiratory chain system activity in rat liver mitochondria.
PubMed:
Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:
Artichoke leaf extract reduces oxidative stress and lipoprotein dyshomeostasis in rats fed on high cholesterol diet.
PubMed:
Effect of artichoke leaf extract on hepatic and cardiac oxidative stress in rats fed on high cholesterol diet.
PubMed:
Artichoke leave extract for chronic hepatitis C - a pilot study.
PubMed:
The effect of artichoke (Cynara scolymus L.) extract on ROS generation in HUVEC cells.
PubMed:
Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress.
PubMed:
The influence of supplementation with artichoke (Cynara scolymus L.) extract on selected redox parameters in rowers.
PubMed:
Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold.
PubMed:
Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial.
PubMed:
Effect of artichoke extract (Cynara scolymus L.) on palmitic-1-14C acid oxidation in rats.
PubMed:
Flavonoids of Cynara scolymus possess potent xanthinoxidase inhibitory activity in vitro but are devoid of hypouricemic effects in rats after oral application.
PubMed:
Effects of artichoke extract supplementation on gonads of cadmium-treated rats.
PubMed:
Clinical uses of artichoke leaf extract.
PubMed:
Research on biomodulatory effect of natural compounds.
PubMed:
Tabletted microspheres containing Cynara scolymus (var. Spinoso sardo) extract for the preparation of controlled release nutraceutical matrices.
PubMed:
Time-resolved spectral studies of blue-green fluorescence of artichoke (Cynara cardunculus L. Var. Scolymus) leaves: identification of chlorogenic acid as one of the major fluorophores and age-mediated changes.
PubMed:
Choleretic effects of yarrow (Achillea millefolium s.l.) in the isolated perfused rat liver.
PubMed:
Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.
PubMed:
Antifungal activity of Cynara scolymus L. extracts.
PubMed:
Purification of cynarases from artichoke (Cynara scolymus L.): enzymatic properties of cynarase A.
PubMed:
Purification and characterization of a milk-clotting aspartic proteinase from globe artichoke (Cynara scolymus L.).
PubMed:
Experimental mycotoxicosis in chickens induced by ochratoxin A and penicillic acid and intervention with natural plant extracts.
PubMed:
Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities.
PubMed:
Artichoke leaf extract reduces symptoms of irritable bowel syndrome and improves quality of life in otherwise healthy volunteers suffering from concomitant dyspepsia: a subset analysis.
PubMed:
Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells.
PubMed:
Effectiveness of artichoke extract in preventing alcohol-induced hangovers: a randomized controlled trial.
PubMed:
Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial.
PubMed:
Validated method for the determination of six metabolites derived from artichoke leaf extract in human plasma by high-performance liquid chromatography-coulometric-array detection.
PubMed:
Screening pharmaceutical preparations containing extracts of turmeric rhizome, artichoke leaf, devil's claw root and garlic or salmon oil for antioxidant capacity.
PubMed:
Occupational rhinitis and bronchial asthma due to artichoke (Cynara scolymus).
PubMed:
Efficacy of different Cynara scolymus preparations on liver complaints.
PubMed:
Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats.
PubMed:
Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action.
PubMed:
Protective properties of artichoke (Cynara scolymus) against oxidative stress induced in cultured endothelial cells and monocytes.
PubMed:
Artichoke (Cynara scolymus L.) byproducts as a potential source of health-promoting antioxidant phenolics.
PubMed:
Electrospray characterization of selected medicinal plant extracts.
PubMed:
Artichoke leaf extract - Recent findings reflecting effects on lipid metabolism, liver and gastrointestinal tracts.
PubMed:
[Action of an extract of artichoke (Cynara scolymus) on cholesterolesterase in vitro].