uncaria tomentosa bark extract
extract of the bark of uncaria tomentosa, rubiaceae
Identification
| Name | uncaria tomentosa bark extract |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for uncaria tomentosa bark extract usage levels up to | not for fragrance use. |
| Recommendation for uncaria tomentosa bark extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
cat's claw bark extract
cats claw bark extract
extract of the bark of uncaria tomentosa, rubiaceae
PubMed:
Evaluation of in vitro absorption, distribution, metabolism, and excretion (ADME) properties of mitragynine, 7-hydroxymitragynine, and mitraphylline.
PubMed:
Acute Toxicity and Determination of the Active Constituents of Aqueous Extract of Uncaria tomentosa Bark in Hyphessobrycon eques.
PubMed:
Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line.
PubMed:
Uncaria tomentosa alkaloidal fraction reduces paracellular permeability, IL-8 and NS1 production on human microvascular endothelial cells infected with dengue virus.
PubMed:
Cat's claw oxindole alkaloid isomerization induced by cell incubation and cytotoxic activity against T24 and RT4 human bladder cancer cell lines.
PubMed:
Mechanisms of herb-induced nephrotoxicity.
PubMed:
Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark.
PubMed:
Studies of biological properties of Uncaria tomentosa extracts on human blood mononuclear cells.
PubMed:
Uncaria tomentosa extracts protect human erythrocyte catalase against damage induced by 2,4-D-Na and its metabolites.
PubMed:
HPLC-PDA method for quinovic acid glycosides assay in Cat's claw (Uncaria tomentosa) associated with UPLC/Q-TOF-MS analysis.
PubMed:
Evaluation of the effect of Uncaria tomentosa extracts on the size and shape of human erythrocytes (in vitro).
PubMed:
Uncaria tomentosa (Willd. ex. Roem. & Schult.) DC. and Eucalyptus globulus Labill. interactions when administered with diazepam.
PubMed:
Uncaria tomentosa aqueous-ethanol extract triggers an immunomodulation toward a Th2 cytokine profile.
PubMed:
Inhibitory mechanisms of two Uncaria tomentosa extracts affecting the Wnt-signaling pathway.
PubMed:
Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition.
PubMed:
Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB.
PubMed:
Evaluation of biological activity of Uncaria tomentosa (Willd.) DC. using the chicken embryo model.
PubMed:
Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing's sarcoma and breast cancer cell lines.
PubMed:
Effect of Alkaloid-Free and Alkaloid-Rich preparations from Uncaria tomentosa bark on mitotic activity and chromosome morphology evaluated by Allium Test.
PubMed:
(13)C, (15)N CPMAS NMR and GIAO DFT calculations of stereoisomeric oxindole alkaloids from Cat's Claw (Uncaria tomentosa).
PubMed:
Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell lines.
PubMed:
Changes in chromosome structure, mitotic activity and nuclear DNA content from cells of Allium Test induced by bark water extract of Uncaria tomentosa (Willd.) DC.
PubMed:
Proapoptotic effect of Uncaria tomentosa extracts.
PubMed:
A water soluble extract from Uncaria tomentosa (Cat's Claw) is a potent enhancer of DNA repair in primary organ cultures of human skin.
PubMed:
Antioxidant activity of ethanolic and aqueous extracts of Uncaria tomentosa (Willd.) DC.
PubMed:
Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis.
PubMed:
Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects.
PubMed:
Involvement of 5-HT2 receptors in the antinociceptive effect of Uncaria tomentosa.
PubMed:
Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction: a mechanism for anti-inflammatory activity.
PubMed:
In vitro immunomodulatory activity of plants used by the Tacana ethnic group in Bolivia.
PubMed:
Morphoanatomical studies of Uncaria tomentosa and Uncaria guianensis bark and leaves.
PubMed:
Identification and quantification of components in extracts of Uncaria tomentosa by HPLC-ES/MS.
PubMed:
C-Med 100, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo.
PubMed:
Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content.
PubMed:
Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae).
PubMed:
The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line.
PubMed:
Improved method for the determination of oxindole alkaloids in Uncaria tomentosa by high performance liquid chromatography.
PubMed:
Investigation of Uña De Gato I. 7-Deoxyloganic acid and 15N NMR spectroscopic studies on pentacyclic oxindole alkaloids from Uncaria tomentosa.
PubMed:
Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection.
PubMed:
Antiinflammatory actions of cat's claw: the role of NF-kappaB.
PubMed:
Pharmacologically active procyanidines from the bark of Uncaria tomentosa.
PubMed:
Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts.
PubMed:
Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda.