guazatine

2-[8-[8-(diaminomethylideneamino)octylamino]octyl]guanidine

C18 H41 N7 MW: 355.57377000

Identification

Nameguazatine
EINECS236-855-3
FDA UNIIC376JTX506
Molecular FormulaC18 H41 N7
Molecular Weight355.57377000
Nikkaji NumberJ1.861I

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 558.38 °C. @ 760.00 mm Hg (est)
Flash Point 557.00 °F. TCC ( 291.50 °C. ) (est)
logP (o/w) 3.048 (est)
Soluble in water, 7.64E+05 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-duck LD50 985 mg/kg
Dermal Toxicityskin-rat LD50 1500 mg/kg
Inhalation Toxicityinhalation-rat LC50 73 mg/m3/4H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for guazatine usage levels up tonot for fragrance use.
Recommendation for guazatine flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

2-[8-[8-( diaminomethylideneamino)octylamino]octyl]guanidine PubMed: Perturbation of polyamine catabolism affects grape ripening of Vitis vinifera cv. Trincadeira. PubMed: Evaluating eco-friendly botanicals (natural plant extracts) as alternatives to synthetic fungicides. PubMed: Guanylated diamines, triamines, and polyamines: chemistry and biological properties. PubMed: Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of H₂O₂ production and transcriptional alteration. PubMed: Inhibition of citrus fungal pathogens by using lactic acid bacteria. PubMed: Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase. PubMed: Involvement of polyamine oxidase in abscisic acid-induced cytosolic antioxidant defense in leaves of maize. PubMed: In vitro and in vivo inhibition of plant polyamine oxidase activity by polyamine analogues. PubMed: Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis. PubMed: LC/ESI/MS method for the quantitative detection of guazatine residues in cereals. PubMed: Analysis of guazatine mixture by LC and LC-MS and antimycotic activity determination of principal components. PubMed: [The mechanism of ABA-induced apoplastic H2O2 accumulation in maize leaves]. PubMed: Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back conversion. PubMed: Analytical method for determining iminoctadine triacetate by LC/ESI/MS using hydrophilic interaction chromatography. PubMed: Inhibition of polyamine and spermine oxidases by polyamine analogues. PubMed: Isolation, identification and antifungal susceptibility of lemon pathogenic and non pathogenic fungi. PubMed: Molecular basis for the binding of competitive inhibitors of maize polyamine oxidase. PubMed: Induction of hypersensitive cell death by hydrogen peroxide produced through polyamine degradation in tobacco plants. PubMed: Inhibition of pig liver and Zea mays L. polyamine oxidase: a comparative study. PubMed: Structural bases for inhibitor binding and catalysis in polyamine oxidase. PubMed: Action against Vibrio cholerae O1 Tox+ of chemical products used in the lemon production. PubMed: Bactericidal activity against Vibrio cholerae of chemical products used in lemon production in Tucumán, Argentina. PubMed: Circulatory failure caused by a fungicide containing iminoctadine and a surfactant: a pharmacological analysis in rats. PubMed: Mechanisms of hypotension in iminoctadine poisoning: pharmacological analysis in rats. PubMed: A fungicide containing iminoctadine causes circulatory failure in acute oral poisoning. PubMed: Postharvest-applied agrochemicals and their residues in fresh fruits and vegetables. PubMed: Hypusine formation in protein by a two-step process in cell lysates. PubMed: A method for the determination of guazatine residues in crops and soil.