guazatine
2-[8-[8-(diaminomethylideneamino)octylamino]octyl]guanidine
Identification
| Name | guazatine |
| EINECS | 236-855-3 |
| FDA UNII | C376JTX506 |
| Molecular Formula | C18 H41 N7 |
| Molecular Weight | 355.57377000 |
| Nikkaji Number | J1.861I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 558.38 °C. @ 760.00 mm Hg (est) |
| Flash Point | 557.00 °F. TCC ( 291.50 °C. ) (est) |
| logP (o/w) | 3.048 (est) |
| Soluble in | water, 7.64E+05 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-duck LD50 985 mg/kg |
| Dermal Toxicity | skin-rat LD50 1500 mg/kg |
| Inhalation Toxicity | inhalation-rat LC50 73 mg/m3/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for guazatine usage levels up to | not for fragrance use. |
| Recommendation for guazatine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
2-[8-[8-(
diaminomethylideneamino)octylamino]octyl]guanidine
PubMed:
Perturbation of polyamine catabolism affects grape ripening of Vitis vinifera cv. Trincadeira.
PubMed:
Evaluating eco-friendly botanicals (natural plant extracts) as alternatives to synthetic fungicides.
PubMed:
Guanylated diamines, triamines, and polyamines: chemistry and biological properties.
PubMed:
Ectopic expression of MdSPDS1 in sweet orange (Citrus sinensis Osbeck) reduces canker susceptibility: involvement of HâOâ production and transcriptional alteration.
PubMed:
Inhibition of citrus fungal pathogens by using lactic acid bacteria.
PubMed:
Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase.
PubMed:
Involvement of polyamine oxidase in abscisic acid-induced cytosolic antioxidant defense in leaves of maize.
PubMed:
In vitro and in vivo inhibition of plant polyamine oxidase activity by polyamine analogues.
PubMed:
Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis.
PubMed:
LC/ESI/MS method for the quantitative detection of guazatine residues in cereals.
PubMed:
Analysis of guazatine mixture by LC and LC-MS and antimycotic activity determination of principal components.
PubMed:
[The mechanism of ABA-induced apoplastic H2O2 accumulation in maize leaves].
PubMed:
Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back conversion.
PubMed:
Analytical method for determining iminoctadine triacetate by LC/ESI/MS using hydrophilic interaction chromatography.
PubMed:
Inhibition of polyamine and spermine oxidases by polyamine analogues.
PubMed:
Isolation, identification and antifungal susceptibility of lemon pathogenic and non pathogenic fungi.
PubMed:
Molecular basis for the binding of competitive inhibitors of maize polyamine oxidase.
PubMed:
Induction of hypersensitive cell death by hydrogen peroxide produced through polyamine degradation in tobacco plants.
PubMed:
Inhibition of pig liver and Zea mays L. polyamine oxidase: a comparative study.
PubMed:
Structural bases for inhibitor binding and catalysis in polyamine oxidase.
PubMed:
Action against Vibrio cholerae O1 Tox+ of chemical products used in the lemon production.
PubMed:
Bactericidal activity against Vibrio cholerae of chemical products used in lemon production in Tucumán, Argentina.
PubMed:
Circulatory failure caused by a fungicide containing iminoctadine and a surfactant: a pharmacological analysis in rats.
PubMed:
Mechanisms of hypotension in iminoctadine poisoning: pharmacological analysis in rats.
PubMed:
A fungicide containing iminoctadine causes circulatory failure in acute oral poisoning.
PubMed:
Postharvest-applied agrochemicals and their residues in fresh fruits and vegetables.
PubMed:
Hypusine formation in protein by a two-step process in cell lysates.
PubMed:
A method for the determination of guazatine residues in crops and soil.