monensin sodium

monensin, monosodium salt

CAS: 22373-78-0 C36 H61 Na O11 MW: 692.86313928

Identification

Namemonensin sodium
CAS Number22373-78-0
EINECS244-941-7
FDA UNII1GS872GAFV
Molecular FormulaC36 H61 Na O11
Molecular Weight692.86313928
MDL NumberMFCD00077826
Beilstein4122200

Regulatory

Physical Properties

Appearance white to pale yellow powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 766.30 °C. @ 760.00 mm Hg (est)
Flash Point 445.00 °F. TCC ( 229.20 °C. ) (est)
logP (o/w) 3.716 (est)
Soluble in water, 1.614 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-cattle LD50 26 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"\nBEHAVIORAL: MUSCLE WEAKNESS\nPERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for monensin sodium usage levels up tonot for fragrance use.
Recommendation for monensin sodium flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

monensin sodium salt monensin, monosodium salt monensin, sodium salt rumensin sodium monensin PubMed: Analysis of veterinary drug and pesticide residues in animal feed by high-resolution mass spectrometry: comparison between time-of-flight and Orbitrap. PubMed: Influence of Ionophore Supplementation on Growth Performance, Dietary Energetics and Carcass Characteristics in Finishing Cattle during Period of Heat Stress. PubMed: Trace level determination of polyether ionophores in feed. PubMed: Effects of monensin on metabolism and production in dairy saanen goats in periparturient period. PubMed: Effect of the granulometric characteristics of monensin sodium on controlling experimental coccidiosis in broiler chickens. PubMed: Determination of ionophore coccidiostats in feeding stuffs by liquid chromatography-tandem mass spectrometry. Part II. Application to cross-contamination levels and non-targeted feed. PubMed: Multi-residue method for detecting coccidiostats at carry-over level in feed by HPLC-MS/MS. PubMed: Greenhouse gas, animal performance, and bacterial population structure responses to dietary monensin fed to dairy cows. PubMed: [The use of monensin premix in dairy cows: simple and essential steps for ensuring its proper use]. PubMed: Long-term assessment of horses and ponies post exposure to monensin sodium in commercial feed. PubMed: Effects of ionophores and antibiotics on in vitro hydrogen sulfide production, dry matter disappearance, and total gas production in cultures with a steam-flaked corn-based substrate with or without added sulfur. PubMed: A randomized herd-level field study of dietary interactions with monensin on milk fat percentage in dairy cows. PubMed: Interaction of molasses and monensin in alfalfa hay- or corn silage-based diets on rumen fermentation, total tract digestibility, and milk production by Holstein cows. PubMed: Chromatographic analysis of banned antibacterial growth promoters in animal feed. PubMed: Effect of monensin delivery method on dry matter intake, body condition score, and metabolic parameters in transition dairy cows. PubMed: Monensin might protect Ontario, Canada dairy cows from paratuberculosis milk-ELISA positivity. PubMed: Efficacy of monensin sodium for the reduction of fecal shedding of Mycobacterium avium subsp. paratuberculosis in infected dairy cattle. PubMed: Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. PubMed: Effect of monensin sodium on lactational performance of autumn- and spring-calving cows. PubMed: The effect of season and monensin sodium on the digestive characteristics of autumn and spring pasture fed to sheep. PubMed: Effect of monensin sodium on histological lesions of naturally occurring bovine paratuberculosis. PubMed: Effect of monensin on milk production and efficiency of dairy cows fed two diets differing in forage to concentrate ratios. PubMed: Effects of ionophore feeding and anthelmintic administration on age and weight at puberty in spring-born beef heifers. PubMed: Outbreaks of proliferative haemorrhagic enteropathy on two pig farms. PubMed: Use of monensin sodium in sheep feeds. PubMed: Prophylactic effect of monensin sodium against experimentally induced paratuberculosis in mice. PubMed: Polyether ionophores--effect on rumen function in feedlot cattle. PubMed: Potential of chemical regulation of food intake and body weight of broiler breeder chicks. PubMed: Virginiamycin and monensin, alone or in combination, in turkey broiler diets. PubMed: Effects of concurrent oral administration of monensin on the toxicity of increasing doses of selenium in lambs. PubMed: Occupational dermatitis in animal feed mill workers. PubMed: Evaluation of anti-coccidial drugs' inhibition of Neospora caninum development in cell cultures. PubMed: Concurrent use of the oxfendazole pulse release bolus and the monensin rumen delivery device in young grazing cattle. PubMed: The effect of monensin against swine dysentery. PubMed: A myopathy of sheep associated with sarcocystis infection and monensin administration. PubMed: Use of monensin sodium against Toxoplasma. PubMed: Influence of lasalocid and monensin plus tylosin on comparative feeding value of steam-flaked versus dry-rolled corn in diets for feedlot cattle. PubMed: Effects of feeding monensin to lactating goats: acetyl coenzyme A carboxylase, hormone-sensitive lipase, plasma glucose, and circulating hormones. PubMed: [Toxicity and nutritive action of Pharmakhim's sodium monensin in weaned lambs]. PubMed: [14C]monensin balance in bile-fistulated ponies. PubMed: Determination of monensin sodium residues in beef liver tissue by liquid chromatography of a fluorescent derivative. PubMed: The effects of dietary monensin sodium upon superovulation and embryo viability from mature cows. PubMed: Effects of feeding monensin sodium to lactating goats: milk composition and ruminal volatile fatty acids. PubMed: [Tolerance, toxicity and residues of Pharmachim's sodium monensin in pigs]. PubMed: Identification and semiquantitation of monensin sodium in liver tissue. PubMed: Comparative toxicology of monensin sodium in laboratory animals. PubMed: Accidental monensin sodium intoxication of feedlot cattle. PubMed: Identification and semiquantitation of monensin sodium in animal feeds by thin layer bioautography. PubMed: Comparison of two forms and two levels of lasalocid with monensin on feedlot cattle performance. PubMed: Effect of monensin sodium on the performance and proportions of rumen volatile fatty acids of Friesian bulls. PubMed: Monensin toxicosis in broiler chickens. PubMed: Delayed monensin sodium toxicity in horses. PubMed: The effect of dietary monensin on th luteinizing hormone response of prepuberal heifers given a multiple gonadotropin-releasing hormone challenge. PubMed: Effect of dietary monensin on ovarian response following gonadotropin treatment in prepuberal heifers. PubMed: Effect of dietary ingredients on monensin toxicity in chicks. PubMed: Toxic myopathy in a dog associated with the presence of monensin in dry food. PubMed: Monensin sodium toxicity in cattle. PubMed: Monensin sodium toxicity in cattle. PubMed: Effect of high dietary copper on the ceca of chicks. PubMed: [Effects of monensin sodium on various hematologic parameters in growing calves]. PubMed: [Effects of monensin sodium on the pH and on the concentration of volatile fatty acids of the ruminal fluid]. PubMed: The influence of monensin sodium upon feather development of male chickens. PubMed: Kinetics of monensin complexation with sodium ions by 23NaNMR spectroscopy. PubMed: Anticoccidial activity of eight compounds in domestic mink. PubMed: Effect of dietary methionine status on response of chicks to coccidial infection. PubMed: Interaction of aflatoxin with Eimeria tenella infection and monensin in young broiler chickens. PubMed: Letter: Monensin sodium in horses.