fenpyroximate
tert-butyl (E)-a-(1,3-dimethyl-5-phenoxypyrazol-4-ylmethyleneaminooxy)-p-toluate
Identification
| Name | fenpyroximate |
| CAS Number | 134098-61-6 |
| FDA UNII | 9W557V4RYA |
| Molecular Formula | C24 H27 N3 O4 |
| Molecular Weight | 421.49699000 |
| MDL Number | MFCD00274596 |
| Nikkaji Number | J1.160.369F |
| Beilstein | 8352707 |
Regulatory
Physical Properties
| Appearance | white crystalline powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 546.22 °C. @ 760.00 mm Hg (est) |
| Flash Point | 543.00 °F. TCC ( 284.10 °C. ) (est) |
| logP (o/w) | 6.443 (est) |
| Soluble in | water, 0.1185 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-mouse LD50 440 mg/kg |
| Dermal Toxicity | skin-rat LD50 > 2000 mg/kg |
| Inhalation Toxicity | inhalation-rat LC50 330 mg/m3/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for fenpyroximate usage levels up to | not for fragrance use. |
| Recommendation for fenpyroximate flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
benzoic acid, 4-((((E)-((1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene)amino)oxy)methyl)-, 1,1-dimethylethyl ester
benzoic acid, 4-[[[[(1E)-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]-, 1,1-dimethylethyl ester
tert-
butyl (E)-a-(1,3-dimethyl-5-phenoxypyrazol-4-ylmethyleneaminooxy)-p-toluate
t-
butyl (E)-alpha-(1,3-dimethyl-5-phenoxypyrazol-4-ylmethyleneaminooxy)-p-toluate
tert-
butyl 4-[({[(1E)-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino}oxy)methyl]benzoate
tert-
butyl 4-[({[(1E)-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylidene]amino}oxy)methyl]benzoate
tert-
butyl 4-[({[(E)-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino}oxy)methyl]benzoate
tert-
butyl 4-[({[(E)-(1,3-dimethyl-5-phenoxy-1Hh-pyrazol-4-yl)methylidene]amino}oxy)methyl]benzoate
tert-
butyl 4-[[(E)-(1,3-dimethyl-5-phenoxy-pyrazol-4-yl)methylideneamino]oxymethyl]benzoate
tert-
butyl4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate
danitron
(E)-4-[[[[(1,3-
dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]benzoic acid 1,1-dimethylethyl ester
4-[[(E)-(1,3-
dimethyl-5-phenoxy-4-pyrazolyl)methylideneamino]oxymethyl]benzoic acid tert-butyl ester
1,1-
dimethylethyl 4-[[[[(1E)-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]benzoate
fujimite
2-
methyl-2-propanyl 4-[({[(E)-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino}oxy)methyl]benzoate
PubMed:
Development of a methodology and evaluation of pesticides against Aceria litchii and its predator Phytoseius intermedius (Acari: Eriophyidae, Phytoseiidae).
PubMed:
Ionic liquid-based totally organic solvent-free emulsification microextraction coupled with high performance liquid chromatography for the determination of three acaricides in fruit juice.
PubMed:
[Determination of ten pesticides of pyrazoles and pyrroles in tea by accelerated solvent extraction coupled with gas chromatography-tandem mass spectrometry].
PubMed:
Acaricide, fungicide and drug interactions in honey bees (Apis mellifera).
PubMed:
Comparative toxicity of acaricides to honey bee (Hymenoptera: Apidae) workers and queens.
PubMed:
Toxicity of acaricides to Raoiella indica and their selectivity for its predator, Amblyseius largoensis (Acari: Tenuipalpidae: Phytoseiidae).
PubMed:
Survival and behavioural response to acaricides of the coconut mite predator Neoseiulus baraki.
PubMed:
A case of near-fatal fenpyroximate intoxication: the role of percutaneous cardiopulmonary support and therapeutic hypothermia.
PubMed:
Residual bioassay to assess the toxicity of Acaricides against Aceria guerreronis (Acari: Eriophyidae) under laboratory conditions.
PubMed:
Evidence of the in vitro genotoxicity of methyl-pyrazole pesticides in human cells.
PubMed:
Risk assessment of selected insecticides on Tamarixia triozae (Hymenoptera: Eulophidae), a parasitoid of Bactericera cockerelli (Hemiptera: Trizoidae).
PubMed:
Acute toxic effects of fenpyroximate acaricide on Guppy (Poecilia reticulata Peters, 1859).
PubMed:
Toxicity assessment of 45 pesticides to the epigeic earthworm Eisenia fetida.
PubMed:
Resistance to acaricides in Italian strains of Tetranychus urticae: toxicological and enzymatic assays.
PubMed:
Fenpyroximate binds to the interface between PSST and 49 kDa subunits in mitochondrial NADH-ubiquinone oxidoreductase.
PubMed:
Acute and population level toxicity of imidacloprid and fenpyroximate on an important egg parasitoid, Trichogramma cacoeciae (Hymenoptera: Trichogrammatidae).
PubMed:
Pyrethroid resistance in the tomato red spider mite, Tetranychus evansi, is associated with mutation of the para-type sodium channel.
PubMed:
Sublethal effects of fenpyroximate and pyridaben on two predatory mite species, Neoseiulus womersleyi and Phytoseiulus persimilis (Acari, Phytoseiidae).
PubMed:
DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity.
PubMed:
Residue analysis of multi-class pesticides in watermelon by LC-MS/MS.
PubMed:
A review: oxidative stress in fish induced by pesticides.
PubMed:
In vitro and in vivo acute toxicity of fenpyroximate to flounder Paralichthys olivaceus and its gill cell line FG.
PubMed:
Characterization of the inhibitor binding site in mitochondrial NADH-ubiquinone oxidoreductase by photoaffinity labeling using a quinazoline-type inhibitor.
PubMed:
Resistance mechanisms to mitochondrial electron transport inhibitors in a field-collected strain of Tetranychus urticae Koch (Acari: Tetranychidae).
PubMed:
Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease.
PubMed:
tert-Butyl 4-({[(E)-1,3-dimethyl-5-phen-oxy-pyrazol-4-yl]meth-yl}amino-oxymeth-yl)benzoate.
PubMed:
Complete maternal inheritance of bifenazate resistance in Tetranychus urticae Koch (Acari: Tetranychidae) and its implications in mode of action considerations.
PubMed:
Multiple resistance and biochemical mechanisms of pyridaben resistance in Tetranychus urticae (Acari: Tetranychidae).
PubMed:
Side effects of five new acaricides on the predator Galendromus occidentalis (Acari, Phytoseiidae).
PubMed:
Evaluation of resistance pattern to fenpyroximate and pyridaben in Tetranychus urticae collected from greenhouses and apple orchards using lethal concentration-slope relationship.
PubMed:
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
PubMed:
Significance of habitat type for the genetic population structure of Panonychus citri (Acari: Tetranychidae).
PubMed:
Fenpyroximate resistance in Tetranychus urticae (Acari: Tetranychidae): cross-resistance and biochemical resistance mechanisms.
PubMed:
Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.
PubMed:
Potentiation of a propargite and fenpyroximate mixture against two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae).
PubMed:
Amiloride inhibition of the proton-translocating NADH-quinone oxidoreductase of mammals and bacteria.
PubMed:
The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I.
PubMed:
Cross-resistance, inheritance, and biochemistry of mitochondrial electron transport inhibitor-acaricide resistance in Tetranychus urticae (Acari: Tetranychidae).
PubMed:
Acaricide toxicity and resistance in larvae of different strains of Tetranychus urticae and Panonychus ulmi (Acari: Tetranychidae).
PubMed:
Incidence and inheritance of resistance to METI-acaricides in European strains of the two-spotted spider mite (Tetranychus urticae) (Acari: Tetranychidae).
PubMed:
Determination of fenpyroximate in apples by supercritical fluid extraction and packed capillary liquid chromatography with UV detection.
PubMed:
A laboratory-based method to measure relative pesticide and spray oil efficacy against broad mite, Polyphagotarsonemus latus (Banks)(Acari: Tarsonemidae).
PubMed:
Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase.