azadirachta indica seed
neem seed (azadirachta indica)
Identification
| Name | azadirachta indica seed |
| IUPAC | azadirachta indica seed |
| CAS Number | 84696-25-3 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for azadirachta indica seed usage levels up to | not for fragrance use. |
| Recommendation for azadirachta indica seed flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
antelaea azadirachta seed
margosa seed
melia azadirachta seed
melia indica seed
neem seed (azadirachta indica)
PubMed:
Morphological effects of neem (Azadirachta indica A. Juss) seed oil with known azadirachtin concentrations on the oocytes of semi-engorged Rhipicephalus sanguineus ticks (Acari: Ixodidae).
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Azadirachta indica treatment on the congenital malformations of fetuses from rats.
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Triterpenoid profiling and functional characterization of the initial genes involved in isoprenoid biosynthesis in neem (Azadirachta indica).
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Morphological alterations in the synganglion and integument of Rhipicephalus sanguineus ticks exposed to aqueous extracts of neem leaves (Azadirachta indica A. JUSS).
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In vitro and in vivo effects of neem tree (Azadirachta indica A. Juss) products on larvae of the sheep nose bot fly (Oestrus ovis L. DÃptera: Oestridae).
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Studies on repellent activity of seed oils alone and in combination on mosquito, Aedes aegypti.
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Antimicrobial efficacy of endodontic irrigants from Azadirachta indica: An in vitro study.
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In vitro acaricidal activity of neem (Azadirachta indica) seed extracts with known azadirachtin concentrations against Rhipicephalus microplus.
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Treatment with Azadirachta indica in diabetic pregnant rats: negative effects on maternal outcome.
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Azadirachta indica mitigates behavioral impairments, oxidative damage, histological alterations and apoptosis in focal cerebral ischemia-reperfusion model of rats.
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Cytotoxic evaluation of Melia azedarach in comparison with, Azadirachta indica and its phytochemical investigation.
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Evaluation of mutagenic and antimutagenic activities of neem (Azadirachta indica) seed oil in the in vitro Ames Salmonella/microsome assay and in vivo mouse bone marrow micronucleus test.
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Removal of free fatty acid in Azadirachta indica (Neem) seed oil using phosphoric acid modified mordenite for biodiesel production.
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Repellency of the oily extract of neem seeds (Azadirachta indica) against Varroa destructor (Acari: Varroidae).
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Purification of Azadirachta indica seed cake and its impact on nutritional and antinutritional factors.
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Inhibitory effects of neem seed oil and its extract on various direct acting and activation-dependant mutagens-induced bacterial mutagenesis.
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Transmission blocking activity of a standardized neem (Azadirachta indica) seed extract on the rodent malaria parasite Plasmodium berghei in its vector Anopheles stephensi.
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Bio-control and plant growth promotion potential of siderophore producing endophytic Streptomyces from Azadirachta indica A. Juss.
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Anticancer biology of Azadirachta indica L (neem): a mini review.
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Antiviral activity and mode of action of extracts from neem seed kernel against duck plague virus in vitro1.
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Cytotoxic and apoptosis-inducing activities of limonoids from the seeds of Azadirachta indica (neem).
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Effect of Azadirachta indica (neem), sodium thiosulphate and calcium chloride on changes in nitrogen transformations and inhibition of nitrification in soil incubated under laboratory conditions.
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Characterization and mosquitocidal potential of neem cake-synthesized silver nanoparticles: genotoxicity and impact on predation efficiency of mosquito natural enemies.
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A study of water relations in neem (Azadirachta indica) seed that is characterized by complex storage behaviour.
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Potential of combining neem (Azadirachta indica A. Juss) seed oil with varietal resistance for the management of the cowpea bruchid, Callosobruchus maculatus (F.).
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Morphological alterations in toxigenic Aspergillus parasiticus exposed to neem (Azadirachta indica) leaf and seed aqueous extracts.
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Acute toxicity study of the oil from Azadirachta indica seed (neem oil).
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'Antiandrogenic properties of neem seed oil (azadirachta indica) in male rat and rabbi'.
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Laboratory and field evaluation of neem (Azadirachta indica A. Juss) and Chinaberry (Melia azedarach L.) oils as repellents against Phlebotomus orientalis and P. bergeroti (Diptera: Psychodidae) in Ethiopia.
PubMed:
Antibacterial activity of Karanj (Pongamia pinnata) and Neem (Azadirachta indica) seed oil: a preliminary report.
PubMed:
Immunocontraceptive activity guided fractionation and characterization of active constituents of neem (Azadirachta indica) seed extracts.
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Purification of the seven tetranortriterpenoids in neem (Azadirachta indica) seed by counter-current chromatography sequentially followed by isocratic preparative reversed-phase high-performance liquid chromatography.
PubMed:
Neem (Azadirachta indica) seed kernel powder retards urease and nitrification activities in different soils at contrasting moisture and temperature regimes.
PubMed:
In vitro acaricidal effect of plant extract of neem seed oil (Azadirachta indica) on egg, immature, and adult stages of Hyalomma anatolicum excavatum (Ixodoidea: Ixodidae).
PubMed:
Purified neem (Azadirachta indica) seed extracts (Praneem) abrogate pregnancy in primates.
PubMed:
Effects of aqueous extract of deoiled neem (Azadirachta Indica A. juss) seed kernel and karanja (Pongamia Glabra vent) seed kernel against Culex quinquefasciatus.
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Oral administration of Azadirachta indica (L.) seed kernel active principle protects rat liver hepatocytes and testis seminiferous tubules from phenobarbitol-induced damage.
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Comparative efficacy of Annona squamosa and Azadirachta indica extracts against Boophilus microplus Izatnagar isolate.
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In vitro antimalarial activity of neem (Azadirachta indica A. Juss) leaf and seed extracts.
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Efficacy of Azadirachta indica extracts against Boophilus microplus.
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Extracts of Azadirachta indica and Melia azedarach seeds inhibit folliculogenesis in albino rats.
PubMed:
Morphological and oil content variation in seeds of Azadirachta indica A. Juss. (Neem) from northern and western provenances of India.
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Effect of Azadirachta indica (neem) on the growth pattern of dermatophytes.
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Comprehensive analyses of genomes, transcriptomes and metabolites of neem tree.
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Larvicidal and ovideterrent properties of neem oil and fractions against the filariasis vector Aedes albopictus (Diptera: Culicidae): a bioactivity survey across production sites.
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Toxicity of Neem Seed Oil against the Larvae of Boophilus decoloratus, A One-Host Tick In Cattle.
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Phenolic acids in neem (Azadirachta indica): a major pre-existing secondary metabolites.
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A study of hypoglycaemic effects of Azadirachta indica (Neem) in normaland alloxan diabetic rabbits.
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Acaricidal effect of herbal extracts against cattle tick Rhipicephalus (Boophilus) microplus using in vitro studies.
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Prediction of desiccation sensitivity in seeds of woody species: a probabilistic model based on two seed traits and 104 species.
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Bioactivity of neem, Azadirachta indica, against spittlebug Mahanarva fimbriolata (Hemiptera: Cercopidae) on sugarcane.
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Larvicidal action of ethanolic extracts from fruit endocarps of Melia azedarach and Azadirachta indica against the dengue mosquito Aedes aegypti.
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Safety evaluation of neem (Azadirachta indica) derived pesticides.
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Inhibition of the growth and development of asexual and sexual stages of drug-sensitive and resistant strains of the human malaria parasite Plasmodium falciparum by Neem (Azadirachta indica) fractions.
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Ethnopharmacognostical survey of Azadirachta indica A. Juss (Meliaceae).
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A new shampoo based on neem (Azadirachta indica) is highly effective against head lice in vitro.
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Molluscicidal effects of neem (Azadirachta indica) extracts on edible tropical land snails.
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A new triterpenoid from Azadirachta indica.
PubMed:
Rapid and sensitive analysis of azadirachtin and related triterpenoids from Neem (Azadirachta indica) by high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
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Two novel azadirachtin derivatives from azadirachta indica
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Toxicological studies on debitterized Neem oil (Azadirachta indica).
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[In vitro insecticidal activity of seed neem oil on Lutzomyia longipalpis (Diptera: Psychodidae)].
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Early post implantation contraceptive effects of a purified fraction of neem (Azadirachta indica) seeds, given orally in rats: possible mechanisms involved.
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Influence of operating parameters on the use of the microwave-assisted process (MAP) for the extraction of azadirachtin-related limonoids from neem (Azadirachta indica) under atmospheric pressure conditions.
PubMed:
Relative toxicity of neem fruit, bitter gourd, and castor seed extracts against the larvae of filaria vector, Culex quinquefasciatus (Say).
PubMed:
Antifeedant activity of extracts from neem,Azadirachta indica, to strawberry aphid,Chaetosiphon fragaefolii.
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Medicinal plants potential and use by pastoral and agro-pastoral communities in Erer Valley of Babile Wereda, Eastern Ethiopia.
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A comprehensive study on characterization of elite Neem chemotypes through mycofloral, tissue-cultural, ecomorphological and molecular analyses using azadirachtin-A as a biomarker.
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Tertiary combination of freeze-dried urine of Indian breeds of cow with plant products against snail Lymnaea acuminata.
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Isolation of antioxidant principle from Azadirachta seed kernels: determination of its role on plant lipoxygenases.
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Efficacy of crude neem seed kernel extracts against natural infestation of Sarcoptes scabiei var. ovis.
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Efficacy of natural products against Callosobruchus chinensis (Coleoptera: Bruchidae) in Nepal.
PubMed:
Three new tetranortriterpenoids from neem seed oil.
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Effect of meliaceous seed extracts on growth and survival ofSpodoptera frugiperda (J.E. Smith).
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Comparison of extraction procedures on the immunocontraceptive activity of neem seed extracts.
PubMed:
Termination of pregnancy in rodents by oral administration of praneem, a purified neem seed extract.
PubMed:
Effect of pest controlling neem and mata-raton leaf extracts on greenhouse gas emissions from urea-amended soil cultivated with beans: a greenhouse experiment.
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Azadirachtin as a larvicide against the horn fly, stable fly, and house fly (Diptera: Muscidae).
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Development of controlled release formulations of azadirachtin-A employing poly(ethylene glycol) based amphiphilic copolymers.
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Antimicrobial activities of skincare preparations from plant extracts.
PubMed:
Assessment of antioxidant capacity and cytotoxicity of selected Malaysian plants.
PubMed:
[Plant extracts in control of Rhipicephalus (Boophilus) microplus (Canestrini, 1887) (Acari: Ixodidae) in laboratory].
PubMed:
[Action of extract and oil neem in the control of Rhipicephalus (Boophilus) microplus (Canestrini, 1887) (Acari: Ixodidae) in laboratory].
PubMed:
Molluscicidal activity of Lawsonia inermis and its binary and tertiary combinations with other plant derived molluscicides.
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Studies on the use of neem products for removal of ammonia from brackishwater.
PubMed:
Studies on the management of root-knot nematode, Meloidogyne incognita-wilt fungus, Fusarium oxysporum disease complex of green gram, Vigna radiata cv ML-1108.
PubMed:
Response and effect of two plant crude extracts on mosquito larvae Culex pipiens.
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Behavioral and developmental effects of neem extracts on Clavigralla scutellaris (Hemiptera: Heteroptera: Coreidae) and its egg parasitoid, Gryon fulviventre (Hymenoptera: Scelionidae).
PubMed:
An efficient method for the purification and characterization of nematicidal azadirachtins A, B, and H, using MPLC and ESIMS.
PubMed:
Efficacy of local neem extracts for sustainable malaria vector control in an African village.
PubMed:
Determination of azadirachtin in agricultural matrixes and commercial formulations by enzyme-linked immunosorbent assay.
PubMed:
Melanogenesis inhibitory, anti-inflammatory, and chemopreventive effects of limonoids from the seeds of Azadirachta indicia A. Juss. (neem).
PubMed:
Production of biopesticides in an in situ cell retention bioreactor.
PubMed:
Fungitoxicity of some higher plants and synergistic activity of their essential oils against Sclerotium rolfsii sacc. causing foot-rot disease of barley.
PubMed:
Actin cytoskeleton as a putative target of the neem limonoid Azadirachtin A.
PubMed:
Glutaraldehyde crosslinked sodium alginate beads containing liquid pesticide for soil application.
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Activity and biological effects of neem products against arthropods of medical and veterinary importance.
PubMed:
Plant products used as mosquito repellents in Guinea Bissau, West Africa.
PubMed:
The toxicity of margosan-O, a product of neem seeds, to selected target and nontarget aquatic invertebrates
PubMed:
Ovicidal activity of neem products (azadirachtin) against Culex tarsalis and Culex quinquefasciatus (Diptera: Culicidae).
PubMed:
Plant immunomodulators for termination of unwanted pregnancy and for contraception and reproductive health.
PubMed:
Effects of the neem tree compounds azadirachtin, salannin, nimbin, and 6-desacetylnimbin on ecdysone 20-monooxygenase activity.
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Bioactivity of phytochemicals in some lesser-known plants and their effects and potential applications in livestock and aquaculture production systems.
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Nimbidin suppresses functions of macrophages and neutrophils: relevance to its antiinflammatory mechanisms.
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First results of the application of a new Neemazal powder formulation in hydroponics against different pest insects.
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Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India.
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Effect of volatiles from neem and other natural products on gonotrophic cycle and oviposition of Anopheles stephensi and An. culicifacies (Diptera: Culicidae).
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Evaluation of ash from some tropical plants of Nigeria for the control of Sclerotium rolfsii Sacc. on wheat (Triticum aestivum L.).