piperazine adipate
hexanedioic acid, compd. with piperazine (1:1)
Identification
| Name | piperazine adipate |
| CAS Number | 142-88-1 |
| EINECS | 205-569-0 |
| FDA UNII | V7P5P122LB |
| Molecular Formula | C10 H20 N2 O4 |
| Molecular Weight | 232.28020000 |
| MDL Number | MFCD00050650 |
Regulatory
Physical Properties
| Appearance | white crystalline powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 338.50 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000018 mmHg @ 25.00 °C. (est) |
| Flash Point | 343.00 °F. TCC ( 172.70 °C. ) (est) |
| logP (o/w) | 0.079 (est) |
Organoleptic Properties
| Odor Strength | none |
| Odor Description | at 100.00 %. |
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 1640 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for piperazine adipate usage levels up to | not for fragrance use. |
| Recommendation for piperazine adipate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
adipic acid, compd. with piperazine (1:1) (8CI)
adiprazina
adiprazine
arduvermin
camin AP
dietelmin
divermex
helmirazin
hexanedioic acid - piperazine (1:1)
hexanedioic acid compd. with piperazine (1:1)
hexanedioic acid, compd. with piperazine (1:1)
hexanedioic acid;piperazine
nometan
oxurasin
oxypaat
oxyzin
pipadox
piperascat
piperaskat
piperazine, monoadipate
vermicompren
vermilass
Google Patents:
Piperazine adipate compositions and treatment of helminth infections therewith
PubMed:
Studies on the control of Toxocara canis in breeding kennels.
PubMed:
Comparative anthelminthic efficacy and safety of Caesalpinia crista seed and piperazine adipate in chickens with artificially induced Ascaridia galli infection.
PubMed:
Study of the acetylcholinesterase activity of Ascaridia galli: kinetic properties and the effect of anthelmintics.
PubMed:
[Immunomodulation in patients with cavernous kidney tuberculosis using piperazine adipinate and amniocene].
PubMed:
[Experience with the prevention of enterobiasis in children from preschool institutions of the Zhitomir district].
PubMed:
[Cleft hand and cleft foot abnormalities as a possible teratogenic side effect of the anthelmintic piperazine?].
PubMed:
The effect of piperazine adipate and parbendazole on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae.
PubMed:
Effect of parbendazole and piperazine adipate on the activity of some enzymes of Ascaridia galli and Heterakis gallinae.
PubMed:
A comparison of the genetic activity of pyrvinium pamoate with that of several other anthelmintic drugs in Saccharomyces cerevisiae.
PubMed:
Integumentomuscular sac of Ascaris lumbricoides suis L: a biomembrane for studies on the transport of chemical substances.
PubMed:
[Effectiveness and influence of piperazine adipinate on the immunological indices of furunculosis patients].
PubMed:
Investigations of anthelminthic activity and synthesis of new derivatives of perhydroazepine, perhydro-1,4-diazepine, perhydro-1,4-oxazepine and perhydro-1,5-oxazocine.
PubMed:
[Study of compounds with potential antiparasitic effect. V. Antihistaminics].
PubMed:
Acute transitory cerebellar dysfunction associated with piperazine adipate.
PubMed:
Application of the isotope technique in pharmacodynamic analysis of penetration of drugs into parasites.
PubMed:
Pyrantel embonate in mass treatment of ascariasis and comparison with piperazine adipate and santonin-kainic acid complex.
PubMed:
[Usefulness of idalbin and piperazine adipate in the treatment of enterobiasis in children].
PubMed:
Piperazine adipate in tropical eosinophilia--a preliminary study.
PubMed:
[Drug control of eelworm in the domestic chicken, using piperazine adipate, with special reference to laying performance].
PubMed:
[Control of ascriasis in the domestic fowl by use of piperazine adipate--with special reference to laying performance].
PubMed:
[Tetramizole and piperazine adipate in the treatment of pigs infected with intestinal nematodes].
PubMed:
[Contribution to the study of infestations with Ascaris lumbricoides in rural environments under the influence of mass helminthiasis control with piperazine adipate (Nematocton)].
PubMed:
[Contribution to the study of the mass treatment of ascariasis with a single dose of piperazine adipate (Nematocton)].
PubMed:
[THE NEUROTOXIC SIDE-EFFECTS OF PIPERAZINE DERIVATIVES STUDIED BY EEG IN CHILDREN. II. PIPERAZINE-ADIPATE, SHORT TREATMENT, PYRIDOXINE PROPHYLAXIS].
PubMed:
Treatment of female mice and their litters with piperazine adipate in the drinking water.
PubMed:
[Clinical trials of an anthelmintic: piperazine adipate].
PubMed:
Studies on the action of cortisone administered with dithiazanine or with piperazine adipate on the course of the invasion with Trichinella spiralis (Owen, 1835) in white mice.
PubMed:
[Considerations on the problem of piperazine adipate therapy of certain parasitic diseases of the digestive tract].
PubMed:
[Changes in blood proteins in silver foxes during the administration of therapeutic portions of piperazine adipate and ethylene tetrachloride].
PubMed:
[Effect of piperazine adipate on the growth of Trichomonas vaginalis Donne, 1836, on T. Vaginalis isolated from male urethras and on T. intestinalis (hominis) Leuckart, 1879].
PubMed:
[Therapy of experimental trichinosis in rats with piperazine adipate and atabrine].
PubMed:
[Examinations on the effectiveness of Hungarian made piperazine adipate against Enterobius vermicularis and Ascaris lumbricoides].
PubMed:
Treatment of roundworm (Ascaris, Ancylostoma and Trichostrongylus) infections with piperazine adipate.
PubMed:
[Piperazine adipate and phosphate in control of ascariasis in foxes].
PubMed:
[Treatment of ascariasis with piperazine adipate; preliminary report].
PubMed:
Treatment of ascariasis in children with piperazine adipate and thiocarbanilate.
PubMed:
[The use of piperazine adipate for the mass treatment of ascariasis].
PubMed:
[Clinical experience with piperazine adipate (vermofrik tablets) in ascariasis].
PubMed:
[Effect of piperazine adipate on Enterobius vermicularis & Ascaris lumbricoides].
PubMed:
[Comparative results of the use of piperazine-adipate and oxygen in the treatment of ascariasis].
PubMed:
[Treatment of oxyuriasis in children with piperazine adipate].
PubMed:
Mass therapy with piperazine adipate in the control of threadworm infestations.
PubMed:
The use of piperazine adipate in ascariasis of captive zebras.
PubMed:
Treatment of ascariasis in children with piperazine adipate.
PubMed:
[Piperazine adipate in therapy of oxyuriasis].
PubMed:
On the anthelmintic efficacy of piperazine adipate.
PubMed:
[Forty cases of ascariasis treated with piperazine adipate].
PubMed:
Preliminary trials with piperazine adipate as a veterinary anthelmintic.
PubMed:
Piperazine adipate: a new anthelmintic agent. II. Toxicological and pharmacological studies.
PubMed:
Piperazine adipate: a new anthelmintic agent. I. Physiochemical properties.
PubMed:
[Piperazine adipate in the treatment of ascariasis and oxyuriasis].