protamine sulfate
vasorelax
Identification
| Name | protamine sulfate |
| CAS Number | 9009-65-8 |
| FDA UNII | 0DE9724IHC |
| MDL Number | MFCD00132091 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-guinea pig LD50 120 mg/kg |
| Dermal Toxicity | subcutaneous-guinea pig LD50 200 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nKIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for protamine sulfate usage levels up to | not for fragrance use. |
| Recommendation for protamine sulfate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
protamine sulphate
vasorelax
PubMed:
Modern analytics for naturally derived complex drug substances: NMR and MS tests for protamine sulfate from chum salmon.
PubMed:
Identification of site-specific heterogeneity in peptide drugs using intact mass spectrometry with electron transfer dissociation.
PubMed:
Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use.
PubMed:
A 1-year drug utilization evaluation of protamine in hospitalized patients to identify possible future roles of heparin and low molecular weight heparin reversal agents.
PubMed:
Neutralizing the anticoagulant activity of ultra-low-molecular-weight heparins using N-acetylglucosamine 6-sulfatase.
PubMed:
Application of quality by design elements for the development and optimization of an analytical method for protamine sulfate.
PubMed:
Purification and characterisation of proteases A and D from Debaryomyces hansenii.
PubMed:
Protease B from Debaryomyces hansenii: purification and biochemical properties.
PubMed:
Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI.
PubMed:
Methods for determination of milt protein and epsilon-polylysine in food additive preparations and processed foods by capillary zone electrophoresis.
PubMed:
Fatal anaphylactoid shock associated with protamine for heparin reversal during anesthesia.
PubMed:
Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition.
PubMed:
A nationwide investigation of a possible protamine drug-product defect.
PubMed:
Lack of cross-reactivity between IgE to salmon and protamine sulfate.
PubMed:
Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene-transfer: implications for human gene therapy.
PubMed:
Lipoprotein lipase is produced, regulated, and functional in rat brain.
PubMed:
Partial Purification and Some Properties of Tyrosine Phenol-Lyase from Aeromonas phenologenes ATCC 29063.
PubMed:
Letter: Protamine sulfate and fish allergy.
PubMed:
Death of Staphylococcus aureus in liquid whole egg near pH 8.