tolylfluanid

methanesulfenamide, 1,1-dichloro-N-[(dimethylamino)sulfonyl]-1-fluoro-N-(4-methylphenyl)-

CAS: 731-27-1 C10 H13 Cl2 F N2 O2 S2 MW: 347.25841320

Identification

Nametolylfluanid
CAS Number731-27-1
EINECS211-986-9
FDA UNII382277YXSG
Molecular FormulaC10 H13 Cl2 F N2 O2 S2
Molecular Weight347.25841320
MDL NumberMFCD00055477
Nikkaji NumberJ6.957D
Beilstein2949607
XlogP33.90 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 96.00 °C. @ 760.00 mm Hg
Boiling Point 365.99 °C. @ 760.00 mm Hg (est)
Flash Point 347.00 °F. TCC ( 175.10 °C. ) (est)
logP (o/w) 3.900
Soluble in water, 0.9 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-guinea pig LD50 250 mg/kg
Dermal Toxicityskin-rat LD50 500 mg/kg
Inhalation Toxicityinhalation-rat LC50 300 mg/m3/4H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for tolylfluanid usage levels up tonot for fragrance use.
Recommendation for tolylfluanid flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

bayer 5712a dichlofluanid-methyl 1,1- dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)methanesulfenamide 1,1- dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)methanesulfenamide (9CI) N-[ dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline N-{[ dichloro(fluoro)methyl]sulfanyl}-N',N'-dimethyl-N-(4-methylphenyl)sulfuric diamide N- dichlorofluoromethanesulphenyl-N',N'-dimethyl-N-p-tolylsulphamide N- dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide N- dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulphamide N,N- dimethyl-N-(4-tolyl)-N-(dichlorofluor-methylthio)-sulfamide N,N- dimethyl-N'-(4-tolyl)-N'-(dichlorfluormethylthio)-sulfamid [German] euparen M methanesulfanenamide, 1,1-dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)- methanesulfenamide, 1,1-dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)- methanesulfenamide, 1,1-dichloro-N-[(dimethylamino)sulfonyl]-1-fluoro-N-(4-methylphenyl)- sulfamide, N-((dichlorofluoromethyl)thio)-N',N'-dimethyl-N-(p-tolyl)- tolyfluanide tolylfluanide PubMed: Emerging pesticide metabolites in groundwater and surface water as determined by the application of a multimethod for 150 pesticide metabolites. PubMed: Effects of five antifouling biocides on settlement and growth of zoospores from the marine macroalga Ulva lactuca L. PubMed: The endocrine disrupting chemical tolylfluanid alters adipocyte metabolism via glucocorticoid receptor activation. PubMed: A sensitive and selective method for the determination of selected pesticides in fruit by gas chromatography/mass spectrometry with negative chemical ionization. PubMed: Comparative efficiency of macroalgal extracts and booster biocides as antifouling agents to control growth of three diatom species. PubMed: Effects of seven antifouling compounds on photosynthesis and inorganic carbon use in sugar kelp Saccharina latissima (Linnaeus). PubMed: Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming. PubMed: The novel endocrine disruptor tolylfluanid impairs insulin signaling in primary rodent and human adipocytes through a reduction in insulin receptor substrate-1 levels. PubMed: Aging of methabenzthiazuron, imidacloprid, and N,N-dimethylsulfamide in silty soils and effects on sorption and dissipation. PubMed: Chromosomal aberrations in ovine lymphocytes exposed in vitro to tolylfluanid. PubMed: Multiresidue determination of 160 pesticides in wines employing mixed-mode dispersive-solid phase extraction and gas chromatography-tandem mass spectrometry. PubMed: Induction of SCEs and DNA fragmentation in bovine peripheral lymphocytes by in vitro exposure to tolylfluanid-based fungicide. PubMed: Development of a new QuEChERS method based on dry ice for the determination of 168 pesticides in paprika using tandem mass spectrometry. PubMed: Influence of P-glycoprotein on embryotoxicity of the antifouling biocides to sea urchin (Strongylocentrotus intermedius). PubMed: Toxicity evaluation of single and mixed antifouling biocides using the Strongylocentrotus intermedius sea urchin embryo test. PubMed: Effect of fungicide Euparen Multi (Tolylfluanid) on the induction of chromosomal aberations in cultivated bovine lymphocytes. PubMed: Acute toxicity and synergism of binary mixtures of antifouling biocides with heavy metals to embryos of sea urchin Glyptocidaris crenularis. PubMed: Booster biocides and microfouling. PubMed: Micronucleus frequency in sheep lymphocytes after in vitro exposure to fungicide tolylfluanid. PubMed: Comparison of QuEChERS sample preparation methods for the analysis of pesticide residues in fruits and vegetables. PubMed: Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation. PubMed: The use of parasites as bioindicators of pesticide exposure. PubMed: Probabilistic acute dietary exposure assessments to captan and tolylfluanid using several European food consumption and pesticide concentration databases. PubMed: Development of an LC-MS/MS method for the determination of pesticides and patulin in apples. PubMed: Predicted concentrations of biocides from antifouling paints in Visakhapatnam Harbour. PubMed: Development of a multi-residue method for the determination of pesticides in cereals and dry animal feed using gas chromatography-tandem quadrupole mass spectrometry II. Improvement and extension to new analytes. PubMed: Screening preharvest/postharvest strategies to prevent fruit rot decay. PubMed: Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris. PubMed: [Occurrence of pesticide residues in raspberries in 2000-2005]. PubMed: Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues. PubMed: Determination of pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate: collaborative study. PubMed: Phytotoxicity of tolylfluanid in tomatoes. PubMed: In vitro effect of pesticides (dichlofluanid, endosulfan, simazine, tolylfluanid and triallate) on proliferative activity of animal derived cell cultures. PubMed: Measurement uncertainty associated with sample processing of oranges and tomatoes for pesticide residue analysis. PubMed: Comparative toxicity of alternative antifouling biocides on embryos and larvae of marine invertebrates. PubMed: Monitoring of pesticide residues in apples, lettuce and potato of the Slovene origin, 2001-04. PubMed: Determination of fungicide residues in field-grown strawberries following different fungicide strategies against gray mold (Botrytis cinerea). PubMed: Baby food production chain: pesticide residues in fresh apples and products. PubMed: Chromosomal aberrations and frequency of micronuclei in sheep subchronically exposed to the fungicide Euparen Multi (tolylfluanid). PubMed: Xenobiotics and the glucocorticoid receptor: additive antagonistic effects on tyrosine aminotransferase activity in rat hepatoma cells. PubMed: Toxicity of pesticides to predatory mites and insects in apple-tree site under field conditions. PubMed: Distribution of multiple pesticide residues in apple segments after home processing. PubMed: Processing factors and variability of pyrimethanil, fenhexamid and tolylfluanid in strawberries. PubMed: Assessment of the stability of pesticides during cryogenic sample processing. 1. Apples. PubMed: Investigation on fungicide residues in greenhouse-grown strawberries. PubMed: Exposure to fungicides in fruit growing: re-entry time as a predictor for dermal exposure. PubMed: Fate of the fungicide tolylfluanid in the pear cold stored in controlled or non controlled atmosphere.