tolylfluanid
methanesulfenamide, 1,1-dichloro-N-[(dimethylamino)sulfonyl]-1-fluoro-N-(4-methylphenyl)-
Identification
| Name | tolylfluanid |
| CAS Number | 731-27-1 |
| EINECS | 211-986-9 |
| FDA UNII | 382277YXSG |
| Molecular Formula | C10 H13 Cl2 F N2 O2 S2 |
| Molecular Weight | 347.25841320 |
| MDL Number | MFCD00055477 |
| Nikkaji Number | J6.957D |
| Beilstein | 2949607 |
| XlogP3 | 3.90 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 96.00 °C. @ 760.00 mm Hg |
| Boiling Point | 365.99 °C. @ 760.00 mm Hg (est) |
| Flash Point | 347.00 °F. TCC ( 175.10 °C. ) (est) |
| logP (o/w) | 3.900 |
| Soluble in | water, 0.9 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-guinea pig LD50 250 mg/kg |
| Dermal Toxicity | skin-rat LD50 500 mg/kg |
| Inhalation Toxicity | inhalation-rat LC50 300 mg/m3/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for tolylfluanid usage levels up to | not for fragrance use. |
| Recommendation for tolylfluanid flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
bayer 5712a
dichlofluanid-methyl
1,1-
dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)methanesulfenamide
1,1-
dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)methanesulfenamide (9CI)
N-[
dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline
N-{[
dichloro(fluoro)methyl]sulfanyl}-N',N'-dimethyl-N-(4-methylphenyl)sulfuric diamide
N-
dichlorofluoromethanesulphenyl-N',N'-dimethyl-N-p-tolylsulphamide
N-
dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide
N-
dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulphamide
N,N-
dimethyl-N-(4-tolyl)-N-(dichlorofluor-methylthio)-sulfamide
N,N-
dimethyl-N'-(4-tolyl)-N'-(dichlorfluormethylthio)-sulfamid [German]
euparen M
methanesulfanenamide, 1,1-dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)-
methanesulfenamide, 1,1-dichloro-N-((dimethylamino)sulfonyl)-1-fluoro-N-(4-methylphenyl)-
methanesulfenamide, 1,1-dichloro-N-[(dimethylamino)sulfonyl]-1-fluoro-N-(4-methylphenyl)-
sulfamide, N-((dichlorofluoromethyl)thio)-N',N'-dimethyl-N-(p-tolyl)-
tolyfluanide
tolylfluanide
PubMed:
Emerging pesticide metabolites in groundwater and surface water as determined by the application of a multimethod for 150 pesticide metabolites.
PubMed:
Effects of five antifouling biocides on settlement and growth of zoospores from the marine macroalga Ulva lactuca L.
PubMed:
The endocrine disrupting chemical tolylfluanid alters adipocyte metabolism via glucocorticoid receptor activation.
PubMed:
A sensitive and selective method for the determination of selected pesticides in fruit by gas chromatography/mass spectrometry with negative chemical ionization.
PubMed:
Comparative efficiency of macroalgal extracts and booster biocides as antifouling agents to control growth of three diatom species.
PubMed:
Effects of seven antifouling compounds on photosynthesis and inorganic carbon use in sugar kelp Saccharina latissima (Linnaeus).
PubMed:
Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming.
PubMed:
The novel endocrine disruptor tolylfluanid impairs insulin signaling in primary rodent and human adipocytes through a reduction in insulin receptor substrate-1 levels.
PubMed:
Aging of methabenzthiazuron, imidacloprid, and N,N-dimethylsulfamide in silty soils and effects on sorption and dissipation.
PubMed:
Chromosomal aberrations in ovine lymphocytes exposed in vitro to tolylfluanid.
PubMed:
Multiresidue determination of 160 pesticides in wines employing mixed-mode dispersive-solid phase extraction and gas chromatography-tandem mass spectrometry.
PubMed:
Induction of SCEs and DNA fragmentation in bovine peripheral lymphocytes by in vitro exposure to tolylfluanid-based fungicide.
PubMed:
Development of a new QuEChERS method based on dry ice for the determination of 168 pesticides in paprika using tandem mass spectrometry.
PubMed:
Influence of P-glycoprotein on embryotoxicity of the antifouling biocides to sea urchin (Strongylocentrotus intermedius).
PubMed:
Toxicity evaluation of single and mixed antifouling biocides using the Strongylocentrotus intermedius sea urchin embryo test.
PubMed:
Effect of fungicide Euparen Multi (Tolylfluanid) on the induction of chromosomal aberations in cultivated bovine lymphocytes.
PubMed:
Acute toxicity and synergism of binary mixtures of antifouling biocides with heavy metals to embryos of sea urchin Glyptocidaris crenularis.
PubMed:
Booster biocides and microfouling.
PubMed:
Micronucleus frequency in sheep lymphocytes after in vitro exposure to fungicide tolylfluanid.
PubMed:
Comparison of QuEChERS sample preparation methods for the analysis of pesticide residues in fruits and vegetables.
PubMed:
Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation.
PubMed:
The use of parasites as bioindicators of pesticide exposure.
PubMed:
Probabilistic acute dietary exposure assessments to captan and tolylfluanid using several European food consumption and pesticide concentration databases.
PubMed:
Development of an LC-MS/MS method for the determination of pesticides and patulin in apples.
PubMed:
Predicted concentrations of biocides from antifouling paints in Visakhapatnam Harbour.
PubMed:
Development of a multi-residue method for the determination of pesticides in cereals and dry animal feed using gas chromatography-tandem quadrupole mass spectrometry II. Improvement and extension to new analytes.
PubMed:
Screening preharvest/postharvest strategies to prevent fruit rot decay.
PubMed:
Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris.
PubMed:
[Occurrence of pesticide residues in raspberries in 2000-2005].
PubMed:
Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues.
PubMed:
Determination of pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate: collaborative study.
PubMed:
Phytotoxicity of tolylfluanid in tomatoes.
PubMed:
In vitro effect of pesticides (dichlofluanid, endosulfan, simazine, tolylfluanid and triallate) on proliferative activity of animal derived cell cultures.
PubMed:
Measurement uncertainty associated with sample processing of oranges and tomatoes for pesticide residue analysis.
PubMed:
Comparative toxicity of alternative antifouling biocides on embryos and larvae of marine invertebrates.
PubMed:
Monitoring of pesticide residues in apples, lettuce and potato of the Slovene origin, 2001-04.
PubMed:
Determination of fungicide residues in field-grown strawberries following different fungicide strategies against gray mold (Botrytis cinerea).
PubMed:
Baby food production chain: pesticide residues in fresh apples and products.
PubMed:
Chromosomal aberrations and frequency of micronuclei in sheep subchronically exposed to the fungicide Euparen Multi (tolylfluanid).
PubMed:
Xenobiotics and the glucocorticoid receptor: additive antagonistic effects on tyrosine aminotransferase activity in rat hepatoma cells.
PubMed:
Toxicity of pesticides to predatory mites and insects in apple-tree site under field conditions.
PubMed:
Distribution of multiple pesticide residues in apple segments after home processing.
PubMed:
Processing factors and variability of pyrimethanil, fenhexamid and tolylfluanid in strawberries.
PubMed:
Assessment of the stability of pesticides during cryogenic sample processing. 1. Apples.
PubMed:
Investigation on fungicide residues in greenhouse-grown strawberries.
PubMed:
Exposure to fungicides in fruit growing: re-entry time as a predictor for dermal exposure.
PubMed:
Fate of the fungicide tolylfluanid in the pear cold stored in controlled or non controlled atmosphere.