propylene glycol alginate
alginic acid ester with 1,2-propane diol
Identification
| Name | propylene glycol alginate |
| CAS Number | 9005-37-2 |
| FDA UNII | 26CD3J2R0C |
| Molecular Formula | C3 H8 O2.xUnspecified |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | 1973 |
| JECFA Food Additive | Propylene Glycol Alginate |
| GSFA Codex | Propylene glycol alginate (405) |
| DG SANTE Food Additives | propylene glycol alginate |
| DG SANTE Food Contact Materials | propylene glycol alginate |
| FEMA Number | 2941 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 9005-37-2 ; PROPYLENE GLYCOL ALGINATE |
| FDA Regulation | FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS |
Physical Properties
| Appearance | white to yellowish brown powder (est) |
| Assay | 99.00 to 100.00 |
| Food Chemicals Codex Listed | Yes |
| Soluble in | alcohol |
| Similar Items | note |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | binding agents |
Organoleptic Properties
| Odor Strength | none |
| Odor Description | at 100.00 %. |
Safety Information
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 7200 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | emulsifiers, flavoring adjuvants, stabilizers, thickeners |
| Recommendation for propylene glycol alginate usage levels up to | not for fragrance use. |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | 1000.00000 |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 800.00000 |
| fruit ices | 800.00000 |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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Potential Uses
Natural Occurrence
Synonyms
alginic acid ester with 1,2-propane diol
hydroxypropyl alginate
kelcoloid
manucol ester e/rep
1,2-
propane diol alginate
propane-1,2-diol alginate
propylene alginate
1,2-
propylene glycol alginate
propylene glycol alginate high viscosity
propylene glycol alginate low viscosity
propyleneglycol alginate
PubMed:
Effects of propylene glycol alginate and sucrose esters on the physicochemical properties of modified starch-stabilized beverage emulsions.
PubMed:
Facile fabrication processes for hydrogel-based microfluidic devices made of natural biopolymers.
PubMed:
New ethanol and propylene glycol free gel formulations containing a minoxidil-methyl-β-cyclodextrin complex as promising tools for alopecia treatment.
PubMed:
Determination of M/G ratio of propylene glycol alginate sodium sulfate by HPLC with pre-column derivatization.
PubMed:
Design and evaluation of polysaccharide-based transdermal films for the controlled delivery of nifedipine.
PubMed:
Tailoring of alginate-gelatin microspheres properties for oral Ciprofloxacin-controlled release against Pseudomonas aeruginosa.
PubMed:
Alginate/PEO-PPO-PEO composite hydrogels with thermally-active plasticity.
PubMed:
Enamel matrix derivative in propylene glycol alginate for treatment of infrabony defects with or without systemic doxycycline: 12- and 24-month results.
PubMed:
Alginate lyase and ciprofloxacin co-immobilization on biopolymeric microspheres for cystic fibrosis treatment.
PubMed:
Biosynthetic hydrogels--studies on chemical and physical characteristics on long-term cellular response for tissue engineering.
PubMed:
Fast-dissolving sublingual films of terbutaline sulfate: formulation and in vitro/in vivo evaluation.
PubMed:
Crosslinked ionic polysaccharides for stimuli-sensitive drug delivery.
PubMed:
An HPLC method for microanalysis and pharmacokinetics of marine sulfated polysaccharide PSS-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles in rat plasma.
PubMed:
Investigation of potential injectable polymeric biomaterials for bone regeneration.
PubMed:
Effects of enamel matrix derivative on remineralisation of initial enamel carious lesions in vitro.
PubMed:
Enamel matrix derivative and transforming growth factor-beta1 in Class III furcation defects. A histomorphometric study in dogs.
PubMed:
Morphology and structure of polymer layers protecting dental enamel against erosion.
PubMed:
Transdermal delivery of venlafaxine hydrochloride: the effects of enhancers on permeation across pig ear skin.
PubMed:
Interfacial and foaming interactions between casein glycomacropeptide (CMP) and propylene glycol alginate.
PubMed:
Thermo-responsive non-woven scaffolds for "smart" 3D cell culture.
PubMed:
Acceleration of tendon-bone healing in anterior cruciate ligament reconstruction using an enamel matrix derivative in a rat model.
PubMed:
Exploratory study on the effectiveness of a standardized extract from Ageratina pichinchensis in patients with chronic venous leg ulcers.
PubMed:
Drug-carrier/hydrogel scaffold for controlled growth of cells.
PubMed:
Integrative design of a poly(ethylene glycol)-poly(propylene glycol)-alginate hydrogel to control three dimensional biomineralization.
PubMed:
Cytotoxicity effects of cryoprotectants as single-component and cocktail vitrification solutions.
PubMed:
Biodegradable microfibers deliver the antitumor drug temozolomide to glioma C6 cells in vitro.
PubMed:
Formulations of zero-order, pH-dependent, sustained release matrix systems by ionotropic gelation of alginate-containing mixtures.
PubMed:
Effects of enamel matrix derivative on vascular endothelial growth factor expression and microvessel density in gingival tissues of periodontal pocket: a comparative study.
PubMed:
Pectin, alginate and gum arabic polymers reduce citric acid erosion effects on human enamel.
PubMed:
Local application of fluvastatin improves peri-implant bone quantity and mechanical properties: a rodent study.
PubMed:
Investigation of curcumin-cyclodextrin inclusion complexation in aqueous solutions containing various alcoholic co-solvents and alginates using an UV-VIS titration method. Studies of curcumin and curcuminoides, XXXV.
PubMed:
Evaluation of polymeric films for buccal drug delivery.
PubMed:
In vitro release of curcumin from vehicles containing alginate and cyclodextrin. Studies of curcumin and curcuminoides. XXXIII.
PubMed:
Synthesis and rheological properties of responsive thickeners based on polysaccharide architectures.
PubMed:
Topical application of statin affects bone healing around implants.
PubMed:
The role of macrophages in the periodontal regeneration using Emdogain gel.
PubMed:
Effect of amelogenin extracellular matrix protein and compression on hard-to-heal venous leg ulcers: follow-up data.
PubMed:
How to improve the storage stability of aqueous polymeric film coatings.
PubMed:
pH-sensitive film coatings: towards a better understanding and facilitated optimization.
PubMed:
Albumin-alginate-coated microspheres: resistance to steam sterilization and to lyophilization.
PubMed:
Emdogain-gel stimulates proliferation of odontoblasts and osteoblasts.
PubMed:
Solubility and stability of curcumin in solutions containing alginate and other viscosity modifying macromolecules. Studies of curcumin and curcuminoids. XXX.
PubMed:
The effect of enamel matrix proteins and deproteinized bovine bone mineral on heterotopic bone formation.
PubMed:
The effect of amelogenins (Xelma) on hard-to-heal venous leg ulcers.
PubMed:
Effect of enamel matrix protein derivative on healing of surgical supra-infrabony periodontal defects in the rat molar: a histomorphometric study.
PubMed:
Coverage of Miller class I and II recession defects using enamel matrix proteins versus coronally advanced flap technique: a 2-year report.
PubMed:
Formation of microcapsules from polyelectrolyte and covalent interactions.
PubMed:
Moderate effect of enamel matrix derivative (Emdogain Gel) on Porphyromonas gingivalis growth in vitro.
PubMed:
The effect of Emdogain on ectopic bone formation in tubes of rat demineralized dentin matrix.
PubMed:
Effects of the combination of hydrophobic polypeptides, iso-alpha acids, and malto-oligosaccharides on beer foam stability.
PubMed:
Dental pulp capping: effect of Emdogain Gel on experimentally exposed human pulps.
PubMed:
Coating alginate microspheres with a serum albumin-alginate membrane: application to the encapsulation of a peptide.
PubMed:
Effect of penetration enhancers on the release and skin permeation of bupranolol from reservoir-type transdermal delivery systems.
PubMed:
Oesophageal bioadhesion of sodium alginate suspensions: particle swelling and mucosal retention.
PubMed:
Effect of heat treatment on bioactivities of enamel matrix derivatives in human periodontal ligament (HPDL) cells.
PubMed:
Towards a fully-synthetic substitute of alginate: development of a new process using thermal gelation and chemical cross-linking.
PubMed:
Effects of a topical enamel matrix derivative on skin wound healing.
PubMed:
Effects of enamel matrix derivative on Porphyromonas gingivalis.
PubMed:
Porcine enamel matrix derivative enhances the formation of reparative dentine and dentine bridges during wound healing of amputated rat molars.
PubMed:
Enamel matrix derivative and titanium implants.
PubMed:
Effects of enamel matrix derivative on mineralized tissue formation during bone wound healing in rat parietal bone defects.
PubMed:
Antibacterial effect of an enamel matrix protein derivative on in vivo dental biofilm vitality.
PubMed:
Effects of cellulose derivatives and poly(ethylene oxide)-poly(propylene oxide) tri-block copolymers (Pluronic)surfactants) on the properties of alginate based microspheres and their interactions with phagocytic cells.
PubMed:
Calcium-alginate gel bead cross-linked with gelatin as microcarrier for anchorage-dependent cell culture.
PubMed:
Effects of enamel matrix derivative to titanium implantation in rat femurs.
PubMed:
Effect of the enamel matrix derivative Emdogain on the growth of periodontal pathogens in vitro.
PubMed:
Comparative study of Emdogain and coronally advanced flap technique in the treatment of human gingival recessions. A prospective controlled clinical study.
PubMed:
Effect of an enamel matrix protein derivative (Emdogain) on ex vivo dental plaque vitality.
PubMed:
Injectable gels for tissue engineering.
PubMed:
Polymers for use in controlled release systems: the effect of surfactants on their swelling properties.
PubMed:
Serum albumin-alginate coated beads: mechanical properties and stability.
PubMed:
Comparative study of the use of poly(glycolic acid), calcium alginate and pluronics in the engineering of autologous porcine cartilage.
PubMed:
Antioxidative activities of several marine polysaccharides evaluated in a phosphatidylcholine-liposomal suspension and organic solvents.
PubMed:
Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defects.
PubMed:
Periodontal regeneration with enamel matrix derivative in one human experimental defect. A case report.
PubMed:
Formulation of enamel matrix derivative for surface coating. Kinetics and cell colonization.
PubMed:
Periodontal regeneration in a buccal dehiscence model in monkeys after application of enamel matrix proteins.
PubMed:
Survival, proliferation, and functions of porcine hepatocytes encapsulated in coated alginate beads: a step toward a reliable bioartificial liver.
PubMed:
Coating alginate beads with cross-linked biopolymers: a novel method based on a transacylation reaction.
PubMed:
The controlled release of prednisolone using alginate gel.
PubMed:
Preparation and evaluation of a controlled-release formulation of nifedipine using alginate gel beads.
PubMed:
Viscoelasticity of anionic polymers and their mucociliary transport on the frog palate.
PubMed:
Dietary effects of propylene glycol alginate in humans.
PubMed:
Isolation and characterization of an alginate lyase from Klebsiella aerogenes.
PubMed:
Inhibition of lipolytic activity in milk by polysaccharides.
PubMed:
[The analysis of polysaccharides used as food additives. VIII. Simple qualitative and semiquantitative procedures for the determination of alginates in food].
PubMed:
The use of alginate ester films on solid supports in the preparation of water-insoluble immunoadsorbents for purification of antigens.