rheum palmatum root
dried, crushed roots of the rhubarb, rheum palmatum l., polygonaceae
Identification
| Name | rheum palmatum root |
| IUPAC | rheum palmatum root |
| CAS Number | 90106-27-7 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | astringents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | astringent, tonic agents |
| Recommendation for rheum palmatum root usage levels up to | not for fragrance use. |
| Recommendation for rheum palmatum root flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
dried, crushed roots of the rhubarb, rheum palmatum l., polygonaceae
rheum potaninii root
rheum qinlingense root
rhubarb root
PubMed:
Emodin Suppresses Maintenance of Stemness by Augmenting Proteosomal Degradation of Epidermal Growth Factor Receptor/Epidermal Growth Factor Receptor Variant III in Glioma Stem Cells.
PubMed:
Emodin enhances ATRA-induced differentiation and induces apoptosis in acute myeloid leukemia cells.
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Rheum palmatum L. and Coptis chinensis Franch., exert antipyretic effect on yeast-induced pyrexia rats involving regulation of TRPV1 and TRPM8 expression.
PubMed:
Synergistic effects of curcumin with emodin against the proliferation and invasion of breast cancer cells through upregulation of miR-34a.
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Emodin suppresses inflammatory responses and joint destruction in collagen-induced arthritic mice.
PubMed:
Profiling of secondary metabolites in tissues from Rheum palmatum L. using laser microdissection and liquid chromatography mass spectrometry.
PubMed:
Downregulation of phosphatase of regenerating liver-3 is involved in the inhibition of proliferation and apoptosis induced by emodin in the SGC-7901 human gastric carcinoma cell line.
PubMed:
Emodin inhibits proinflammatory responses and inactivates histone deacetylase 1 in hypoxic rheumatoid synoviocytes.
PubMed:
Antiproliferative and antimetastatic effects of emodin on human pancreatic cancer.
PubMed:
[Survey and pathogen identification of rhubarb diseases in Gansu province].
PubMed:
Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew.
PubMed:
Investigations of free anthraquinones from rhubarb against alpha-naphthylisothiocyanate-induced cholestatic liver injury in rats.
PubMed:
Involvement of matrix metalloproteinases on the inhibition of cells invasion and migration by emodin in human neuroblastoma SH-SY5Y cells.
PubMed:
[Biotransformation of podophyllotoxin by cell suspension culture and root culture of Rheum palmatum].
PubMed:
The biogeochemistry of selenium in Sunan grassland, Gansu, Northwest China, casts doubt on the belief that Marco Polo reported selenosis for the first time in history.
PubMed:
Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation.
PubMed:
Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones.
PubMed:
Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor.
PubMed:
Aloe-emodin induces in vitro G2/M arrest and alkaline phosphatase activation in human oral cancer KB cells.
PubMed:
Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC).
PubMed:
Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-Ll cells.
PubMed:
Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin.
PubMed:
[Induction of hairy roots and anthraquinone production in Rheum palmatum].
PubMed:
Evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities.
PubMed:
Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation.
PubMed:
Release of nucleophosmin from the nucleus: Involvement in aloe-emodin-induced human lung non small carcinoma cell apoptosis.
PubMed:
Signaling pathway for aloe-emodin-induced apoptosis in human H460 lung nonsmall carcinoma cell.
PubMed:
Botanical medicines for the urinary tract.
PubMed:
Inducible nitric oxide synthase inhibitors of Chinese herbs III. Rheum palmatum.
PubMed:
[Effect of salicylic acid on production of anthracene derivatives in a culture of Rheum palmatum L. in vitro].
PubMed:
[Anthraquinone production and analysis in the hairy root cultures of Rheum palmatum L].
PubMed:
Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma.
PubMed:
Effects and mechanisms of emodin on cell death in human lung squamous cell carcinoma.
PubMed:
[Effect of the biotic elicitor, Candida utilis, on the production of anthracene derivatives in a tissue culture of Rheum palmatum L].
PubMed:
[Production of anthracene derivatives in elicited tissue cultures of Rheum palmatum L].
PubMed:
[Studies on polysaccharide of Rheum palmatum L].
PubMed:
Antitrichomonal action of emodin in mice.
PubMed:
[Experimental study on effects of 18 kinds of Chinese herbal medicine for synthesis of thromboxane A2 and PGI2].
PubMed:
[Analysis of the polyphenols in the root of Rheum palmatum L].