artemisia annua
annus wormwood
Identification
| Name | artemisia annua |
| IUPAC | artemisia annua |
| CAS Number | 84775-74-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for artemisia annua usage levels up to | not for fragrance use. |
| Recommendation for artemisia annua flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
artemisia annua fo. macrocephala
artemisia chamomilla
artemisia stewartii
artemisia wadei
annual
wormwood
annus
wormwood
PubMed:
Enhanced Photosynthesis and Carbon Metabolism Favor Arsenic Tolerance in Artemisia annua, a Medicinal Plant as Revealed by Homology-Based Proteomics.
PubMed:
Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua.
PubMed:
Flower morphology and floral sequence in Artemisia annua (Asteraceae)1.
PubMed:
Anthelmintic activity of Artemisia annua L. extracts in vitro and the effect of an aqueous extract and artemisinin in sheep naturally infected with gastrointestinal nematodes.
PubMed:
Essential Oil of Artemisia annua L.: An Extraordinary Component with Numerous Antimicrobial Properties.
PubMed:
Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts.
PubMed:
The physiological response of Artemisia annua L. to salt stress and salicylic acid treatment.
PubMed:
Effects of Artemisia annua and Foeniculum vulgare on chickens highly infected with Eimeria tenella (phylum Apicomplexa).
PubMed:
Metabolomics coupled with pattern recognition and pathway analysis on potential biomarkers in liver injury and hepatoprotective effects of yinchenhao.
PubMed:
Artesunate induces apoptosis through caspase-dependent and -independent mitochondrial pathways in human myelodysplastic syndrome SKM-1 cells.
PubMed:
Algicidal effects of four Chinese herb extracts on bloom-forming Microcystis aeruginosa and Chlorella pyrenoidosa.
PubMed:
T-DNA insertion alters the terpenoid content composition and bioactivity of transgenic Artemisia annua.
PubMed:
Pharmacokinetics of artemisinin delivered by oral consumption of Artemisia annua dried leaves in healthy vs. Plasmodium chabaudi-infected mice.
PubMed:
Anti-tumour effects of polysaccharides isolated from Artemisia annua L by inducing cell apoptosis and immunomodulatory anti-hepatoma effects of polysaccharides.
PubMed:
Overexpression of allene oxide cyclase improves the biosynthesis of artemisinin in Artemisia annua L.
PubMed:
Effects of overexpression of AaWRKY1 on artemisinin biosynthesis in transgenic Artemisia annua plants.
PubMed:
A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control.
PubMed:
Antimicrobial activity of artemisinin and precursor derived from in vitro plantlets of Artemisia annua L.
PubMed:
Metabolic engineering of plants for artemisinin synthesis.
PubMed:
The effects of combining Artemisia annua and Curcuma longa ethanolic extracts in broilers challenged with infective oocysts of Eimeria acervulina and E. maxima.
PubMed:
[Artemisinin: a natural product for fighting against cancer].
PubMed:
Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway.
PubMed:
Potential ecological roles of artemisinin produced by Artemisia annua L.
PubMed:
Antimalarial properties of Artemisia vulgaris L. ethanolic leaf extract in a Plasmodium berghei murine malaria model.
PubMed:
Four ardeemin analogs from endophytic Aspergillus fumigatus SPS-02 and their reversal effects on multidrug-resistant tumor cells.
PubMed:
Transgenic approach to increase artemisinin content in Artemisia annua L.
PubMed:
Arsenic, chromium and NaCl induced artemisinin biosynthesis in Artemisia annua L.: a valuable antimalarial plant.
PubMed:
Differential transcriptome analysis of glandular and filamentous trichomes in Artemisia annua.
PubMed:
Pyrolytic and kinetic analysis of two coastal plant species: Artemisia annua and Chenopodium glaucum.
PubMed:
Studies on the expression of linalool synthase using a promoter-β-glucuronidase fusion in transgenic Artemisia annua.
PubMed:
Metabolic analysis of the increased adventitious rooting mutant of Artemisia annua reveals a role for the plant monoterpene borneol in adventitious root formation.
PubMed:
Artemisinins: pharmacological actions beyond anti-malarial.
PubMed:
Simulated digestion of dried leaves of Artemisia annua consumed as a treatment (pACT) for malaria.
PubMed:
Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
PubMed:
Kinetic analysis of cytochrome P450 reductase from Artemisia annua reveals accelerated rates of NADH-dependent flavin reduction.
PubMed:
Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling.
PubMed:
Combination of ERG9 Repression and Enzyme Fusion Technology for Improved Production of Amorphadiene in Saccharomyces cerevisiae.
PubMed:
Studies on the expression of sesquiterpene synthases using promoter-β-glucuronidase fusions in transgenic Artemisia annua L.
PubMed:
Effect of prolonged water stress on specialized secondary metabolites, peltate glandular trichomes, and pathway gene expression in Artemisia annua L.
PubMed:
Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract--possible synergistic and resistance mechanisms.
PubMed:
Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivo.
PubMed:
Synergism of cytotoxicity effects of triptolide and artesunate combination treatment in pancreatic cancer cell lines.
PubMed:
Strong larvicidal potential of Artemisia annua leaf extract against malaria (Anopheles stephensi Liston) and dengue (Aedes aegypti L.) vectors and bioassay-driven isolation of the marker compounds.
PubMed:
Cytotoxicity of dihydroartemisinin toward Molt-4 cells attenuated by N-tert-butyl-alpha-phenylnitrone and deferoxamine.
PubMed:
Inhibition of phenylpropanoid biosynthesis in Artemisia annua L.: a novel approach to reduce oxidative browning in plant tissue culture.
PubMed:
The synergistic anticancer effect of artesunate combined with allicin in osteosarcoma cell line in vitro and in vivo.
PubMed:
Ethnochemistry and human rights.
PubMed:
Enhanced apoptotic effects of dihydroartemisinin-aggregated gelatin and hyaluronan nanoparticles on human lung cancer cells.
PubMed:
Fast and reliable artemisinin determination from different Artemisia annua leaves based alimentary products by high performance liquid chromatography-tandem mass spectrometry.
PubMed:
Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions.
PubMed:
The complexity of medicinal plants: the traditional Artemisia annua formulation, current status and future perspectives.
PubMed:
[Effect of fertilization on phenolic components and antioxidant activities of Artemisia annua].
PubMed:
[Allelopathic effect of artemisinin on green algae].
PubMed:
Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.
PubMed:
Effect of long-term salinity on cellular antioxidants, compatible solute and fatty acid profile of Sweet Annie (Artemisia annua L.).
PubMed:
A rapid method for the determination of artemisinin and its biosynthetic precursors in Artemisia annua L. crude extracts.
PubMed:
Larvicidal, oviposition, and ovicidal effects of Artemisia annua (Asterales: Asteraceae) against Aedes aegypti, Anopheles sinensis, and Culex quinquefasciatus (Diptera: Culicidae).
PubMed:
Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis.
PubMed:
Utilization of intron-flanking EST-specific markers in the genetic characterization of Artemisia annua genotypes from the trans-Himalayan region of Ladakh, India.
PubMed:
[Interspecific association of companion species in Artemisia annua community in southwest of China].
PubMed:
[Variation of content of artemisic acid in different growth stages of Artemisia annua].
PubMed:
Transcriptome Analysis of Thapsia laciniata Rouy Provides Insights into Terpenoid Biosynthesis and Diversity in Apiaceae.
PubMed:
Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis.
PubMed:
Preparation and application of reversed phase Chromatorotor for the isolation of natural products by centrifugal preparative chromatography.
PubMed:
The metabolite chemotype of Nicotiana benthamiana transiently expressing artemisinin biosynthetic pathway genes is a function of CYP71AV1 type and relative gene dosage.
PubMed:
Dihydroartemisinin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model.
PubMed:
The use of combining ability analysis to identify elite parents for Artemisia annua F1 hybrid production.
PubMed:
Toxic essential oils. Part II: chemical, toxicological, pharmacological and microbiological profiles of Artemisia annua L. volatiles.
PubMed:
Quantitative structure-activity relationships of the antimalarial agent artemisinin and some of its derivatives - a DFT approach.
PubMed:
High-level semi-synthetic production of the potent antimalarial artemisinin.
PubMed:
Differentially expressed genes during contrasting growth stages of Artemisia annua for artemisinin content.
PubMed:
Proteomics analysis of hepatoprotective effects for scoparone using MALDI-TOF/TOF mass spectrometry with bioinformatics.
PubMed:
Is artemisinin the only antiplasmodial compound in the Artemisia annua tea infusion? An in vitro study.
PubMed:
Indole-3-acetic acid production by endophytic Streptomyces sp. En-1 isolated from medicinal plants.
PubMed:
Feeding Artemisia annua alters digesta pH and muscle lipid oxidation products in broiler chickens.
PubMed:
AaERF1 positively regulates the resistance to Botrytis cinerea in Artemisia annua.
PubMed:
The quest for affordable artemisinin.
PubMed:
Prevalence of sensitization to weed pollens of Humulus scandens, Artemisia vulgaris, and Ambrosia artemisiifolia in northern China.
PubMed:
AaORA, a trichome-specific AP2/ERF transcription factor of Artemisia annua, is a positive regulator in the artemisinin biosynthetic pathway and in disease resistance to Botrytis cinerea.
PubMed:
Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.
PubMed:
Overexpression of the Artemisia orthologue of ABA receptor, AaPYL9, enhances ABA sensitivity and improves artemisinin content in Artemisia annua L.
PubMed:
The use of health functional foods in gastrointestinal cancer patients.
PubMed:
Inhibitory effect of dihydroartemisinin against phorbol ester-induced cyclooxygenase-2 expression in macrophages.
PubMed:
Knowledge map of artemisinin research in SCI and Medline database.
PubMed:
Malaria drug made in yeast causes market ferment.
PubMed:
Bioassay of Artemisia annua leaf extracts and artemisinin against larvae of Culex quinquefasciatus and Culex tritaeniorhynchus.
PubMed:
Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies.
PubMed:
Marked enhancement in the artemisinin content and biomass productivity in Artemisia annua L. shoots co-cultivated with Piriformospora indica.
PubMed:
Antimalarial activities of medicinal plants and herbal formulations used in Thai traditional medicine.
PubMed:
The discovery of Artemisia annua L. in the Shengjindian cemetery, Xinjiang, China and its implications for early uses of traditional Chinese herbal medicine qinghao.
PubMed:
Dried whole plant Artemisia annua as an antimalarial therapy.
PubMed:
Anti-allergic action of anti-malarial drug artesunate in experimental mast cell-mediated anaphylactic models.
PubMed:
An endophytic Pseudonocardia species induces the production of artemisinin in Artemisia annua.
PubMed:
Comparative functional analysis of CYP71AV1 natural variants reveals an important residue for the successive oxidation of amorpha-4,11-diene.
PubMed:
Enhanced IL-12p40 production in LPS-stimulated macrophages by inhibiting JNK activation by artemisinin.
PubMed:
Development of the protocol for purification of artemisinin based on combination of commercial and computationally designed adsorbents.
PubMed:
Artemisinin production and precursor ratio in full grown Artemisia annua L. plants subjected to external stress.
PubMed:
Trichome-specific expression of the amorpha-4,11-diene 12-hydroxylase (cyp71av1) gene, encoding a key enzyme of artemisinin biosynthesis in Artemisia annua, as reported by a promoter-GUS fusion.
PubMed:
Metabolomics study on the hepatoprotective effect of scoparone using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry.
PubMed:
In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusions prepared from Artemisia annua L. cultivated in the Brazilian Amazon.
PubMed:
[Influence of different processing techniques of massa medicata fermentata on their amylase activity].
PubMed:
Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways.
PubMed:
[Plasmid pCQ4 and its phage phiCQ4 of endophytic Streptomyces sp. from Artemisia annua L].
PubMed:
Anti-inflammatory effect and modulation of cytochrome P450 activities by Artemisia annua tea infusions in human intestinal Caco-2 cells.
PubMed:
The effect of roots and media constituents on trichomes and artemisinin production in Artemisia annua L.
PubMed:
Overexpression of the cytochrome P450 monooxygenase (cyp71av1) and cytochrome P450 reductase (cpr) genes increased artemisinin content in Artemisia annua (Asteraceae).
PubMed:
Molecular characterization of artemisia virus A, a new sobemovirus isolated from Artemisia annua.
PubMed:
Effects of artemisinin on photosystem II performance of Microcystis aeruginosa by in vivo chlorophyll fluorescence.
PubMed:
[Effect of artemisinin on the expressions of GRalpha mRNA, GRbeta mRNA and P300/CBP protein in lupus nephritis mice].
PubMed:
Automating gene library synthesis by structure-based combinatorial protein engineering: examples from plant sesquiterpene synthases.
PubMed:
Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway.
PubMed:
Characterization of cytochrome P450 monooxygenases isolated from trichome enriched fraction of Artemisia annua L. leaf.
PubMed:
First-time comparison of the in vitro antimalarial activity of Artemisia annua herbal tea and artemisinin.
PubMed:
Antihistomonal effects of artemisinin and Artemisia annua extracts in vitro could not be confirmed by in vivo experiments in turkeys and chickens.
PubMed:
[Impact of artesunate on the expression and secretion of transforming growth factor-b1 of primary rat hepatic stellate cells].
PubMed:
Extracts of Artemisia annua leaves and seeds mediate programmed cell death in Leishmania donovani.
PubMed:
Thaxtomin A-deficient endophytic Streptomyces sp. enhances plant disease resistance to pathogenic Streptomyces scabies.
PubMed:
Investigation of glandular trichome proteins in Artemisia annua L. using comparative proteomics.
PubMed:
A concise synthesis of (+)-artemisinin.
PubMed:
Immunomodulatory and anti-inflammatory properties of artesunate in experimental colitis.
PubMed:
The effect of Artemisia annua on broiler performance, on intestinal microbiota and on the course of a Clostridium perfringens infection applying a necrotic enteritis disease model.
PubMed:
Effect of external stress on density and size of glandular trichomes in full-grown Artemisia annua, the source of anti-malarial artemisinin.
PubMed:
Pseudonocardia antimicrobica sp. nov., a novel endophytic actinomycete associated with Artemisia annua L. (sweet wormwood).
PubMed:
[Relative expression of genes involved in artemisinin biosynthesis and artemisinin accumulation in different tissues of Artemisia annua].
PubMed:
Biochemical characterization and identification of a cinnamyl alcohol dehydrogenase from Artemisia annua.
PubMed:
The impact of impurities in various crude A. annua extracts on the analysis of artemisinin by liquid chromatographic methods.
PubMed:
A safety assessment of the antimalarial herb Artemisia annua during pregnancy in Wistar rats.
PubMed:
Biochemical and haematological evaluation of repeated dose exposure of male Wistar rats to an ethanolic extract of Artemisia annua.
PubMed:
Characterization of a novel ERF transcription factor in Artemisia annua and its induction kinetics after hormones and stress treatments.
PubMed:
[Analysis of SSR information in EST resource of sweet wormwood (Artemisia annua) and development of EST-SSR marker].
PubMed:
Anti-Helicobacter pylori potential of artemisinin and its derivatives.
PubMed:
Tetraoxanes: synthetic and medicinal chemistry perspective.
PubMed:
The flavonoids casticin and artemetin are poorly extracted and are unstable in an Artemisia annua tea infusion.
PubMed:
Isolation and identification of an anti-algal compound from Artemisia annua and mechanisms of inhibitory effect on algae.
PubMed:
Efficient Method for Agrobacterium Mediated Transformation of Artemisia annua L.
PubMed:
Chemical composition of Artemisia annua L. leaves and antioxidant potential of extracts as a function of extraction solvents.
PubMed:
Dihydroartemisinin-induced inhibition of proliferation in BEL-7402 cells: an analysis of the mitochondrial proteome.
PubMed:
Functional expression and characterization of sesquiterpene synthases from Artemisia annua L. using transient expression system in Nicotiana benthamiana.
PubMed:
Microbial transformation of antimalarial terpenoids.
PubMed:
Ethnopharmacology in overdrive: the remarkable anti-HIV activity of Artemisia annua.
PubMed:
Pharmacokinetics and tissue distribution study of scoparone in rats by ultraperformance liquid-chromatography with tandem high-definition mass spectrometry.
PubMed:
[Malaria treatment--herbal therapy in new clothes].
PubMed:
Exogenous nitric oxide donor protects Artemisia annua from oxidative stress generated by boron and aluminium toxicity.
PubMed:
Artemisinic acid is a regulator of adipocyte differentiation and C/EBP δ expression.
PubMed:
Cloning and characterization of trichome-specific promoter of cpr71av1 gene involved in artemisinin biosynthesis in Artemisia annua L.
PubMed:
Streptomyces endophyticus sp. nov., an endophytic actinomycete isolated from Artemisia annua L.
PubMed:
[Studies on allelopathic effect of artemisinin on rhizobium].
PubMed:
Chemical composition and antibacterial activity of the volatile oil from seeds of Artemisia annua L. from Iran.
PubMed:
In-Vitro Assessment of the Acaricidal Properties of Artemisia annua and Zataria multiflora Essential Oils to Control Cattle Ticks.
PubMed:
Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo.
PubMed:
Phytochemical analysis of a herbal tea from Artemisia annua L.
PubMed:
Effects of the antimalarial drugs ferroquine and artesunate on Plasmodium yoelii yoelii gametocytegenesis and vectorial transmission.
PubMed:
Computational identification of sweet wormwood (Artemisia annua) microRNA and their mRNA targets.
PubMed:
Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective.
PubMed:
[Cloning and distribution pattern of HMGR gene conserved fragment in Alisma orientale].
PubMed:
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin.
PubMed:
Effect of sweet wormwood Artemisia annua crude leaf extracts on some biological and physiological characteristics of the lesser mulberry pyralid, Glyphodes pyloalis.
PubMed:
Effect of cadmium on photosynthetic pigments, lipid peroxidation, antioxidants, and artemisinin in hydroponically grown Artemisia annua.
PubMed:
Trichome isolation with and without fixation using laser microdissection and pressure catapulting followed by RNA amplification: expression of genes of terpene metabolism in apical and sub-apical trichome cells of Artemisia annua L.
PubMed:
Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes.
PubMed:
Mining of miRNAs and potential targets from gene oriented clusters of transcripts sequences of the anti-malarial plant, Artemisia annua.
PubMed:
Generation of the potent anti-malarial drug artemisinin in tobacco.
PubMed:
Use of Artemisia annua as a natural coccidiostat in free-range broilers and its effects on infection dynamics and performance.
PubMed:
Pseudonocardia xishanensis sp. nov., an endophytic actinomycete isolated from the roots of Artemisia annua L.
PubMed:
Effects of Environmental Factors on Growth and Artemisinin Content of Artemisia annua L.
PubMed:
Anti-inflammatory and immunomodulatory mechanisms of artemisinin on contact hypersensitivity.
PubMed:
The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L.
PubMed:
[Isolation and characterization of promoter of ADS from Artemisia annua].
PubMed:
Isolation and characterization of culturable endophytic actinobacteria associated with Artemisia annua L.
PubMed:
Dihydroartiminisin inhibits the growth and metastasis of epithelial ovarian cancer.
PubMed:
UV-B and UV-C pre-treatments induce physiological changes and artemisinin biosynthesis in Artemisia annua L. - an antimalarial plant.
PubMed:
Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells.
PubMed:
The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine.
PubMed:
Anthelmintic effect of artesunate in experimental heterophyid infection.
PubMed:
Monitoring of artemisinin, dihydroartemisinin, and artemether in environmental matrices using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS).
PubMed:
In vitro evaluation of the cytotoxic and genotoxic effects of artemether, an antimalarial drug, in a gastric cancer cell line (PG100).
PubMed:
[Effects of inoculating arbuscular mycorrhizal fungi on Artemisia annua growth and its officinal components].
PubMed:
Simultaneous isolation of artemisinin and its precursors from Artemisia annua L. by preparative RP-HPLC.
PubMed:
Volatile fingerprints of artemisinin-rich Artemisia annua cultivars by headspace solid-phase microextraction gas chromatography/ mass spectrometry.
PubMed:
Searching for artemisinin production improvement in plants and microorganisms.
PubMed:
Sphingomonas endophytica sp. nov., isolated from Artemisia annua L.
PubMed:
Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin.
PubMed:
Medicinal chemistry perspectives of trioxanes and tetraoxanes.
PubMed:
Status of carbohydrate, protein and lipid profile in the mosquito larvae treated with certain phytoextracts.
PubMed:
[Climate suitable rank distribution of artemisinin content of Artemisia annua in China].
PubMed:
In vitro evaluation of the genotoxic and cytotoxic effects of artesunate, an antimalarial drug, in human lymphocytes.
PubMed:
Arsenic-induced changes in morphological, physiological, and biochemical attributes and artemisinin biosynthesis in Artemisia annua, an antimalarial plant.
PubMed:
Anti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathway.
PubMed:
Pseudonocardia serianimatus sp. nov., a novel actinomycete isolated from the surface-sterilized leaves of Artemisia annua L.
PubMed:
Cytotoxicity of ethanolic extracts of Artemisia annua to Molt-4 human leukemia cells.
PubMed:
Trichomes + roots + ROS = artemisinin: regulating artemisinin biosynthesis in Artemisia annua L.
PubMed:
Over-expression of HMG-CoA reductase and amorpha-4,11-diene synthase genes in Artemisia annua L. and its influence on artemisinin content.
PubMed:
Characterization of the first specific Jasmonate biosynthetic pathway gene allene oxide synthase from Artemisia annua.
PubMed:
Artemisinin production in Artemisia annua: studies in planta and results of a novel delivery method for treating malaria and other neglected diseases.
PubMed:
Rhodococcus artemisiae sp. nov., an endophytic actinobacterium isolated from the pharmaceutical plant Artemisia annua L.
PubMed:
Plant extracts to control Alternaria alternata in Murcott tangor fruits.
PubMed:
Characterization of development and artemisinin biosynthesis in self-pollinated Artemisia annua plants.
PubMed:
Validation, transfer and measurement uncertainty estimation of an HPLC-UV method for the quantification of artemisinin in hydro alcoholic extracts of Artemisia annua L.
PubMed:
In vitro trematocidal effects of crude alcoholic extracts of Artemisia annua, A. absinthium, Asimina triloba, and Fumaria officinalis: trematocidal plant alcoholic extracts.
PubMed:
Sedative effects of Iranian Artemisia annua in mice: possible benzodiazepine receptors involvement.
PubMed:
The content of artemisinin in the Artemisia annua tea infusion.
PubMed:
Artemisinin biosynthesis enhancement in transgenic Artemisia annua plants by downregulation of the β-caryophyllene synthase gene.
PubMed:
Evaluation and pharmacovigilance of projects promoting cultivation and local use of Artemisia annua for malaria.
PubMed:
β-Cyclodextrins enhance artemisinin production in Artemisia annua suspension cell cultures.
PubMed:
Chemical Compositionand Anti-acetyl cholinesterase Activity of Flower Essential Oils of Artemisiaannuaat Different Flowering Stage.
PubMed:
Enhancement of artemisinin content in tetraploid Artemisia annua plants by modulating the expression of genes in artemisinin biosynthetic pathway.
PubMed:
Millet-porridge with Artemisia annua as first aid for African children with malaria?
PubMed:
In vitro activity of Artemisia annua L (Asteraceae) extracts against Rhipicephalus (Boophilus) microplus.
PubMed:
Variation in the volatile constituents of Artemisia annua var. CIM-Arogya during plant ontogeny.
PubMed:
Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions.
PubMed:
Relative expression of genes of terpene metabolism in different tissues of Artemisia annua L.
PubMed:
Artemisia annua extracts, artemisinin and 1,8-cineole, prevent fruit infestation by a major, cosmopolitan pest of apples.
PubMed:
Artemisinin evaluation in Romanian Artemisia annua wild plants using a new HPLC/MS method.
PubMed:
[Diversity and cluster analysis on agronomic traits of Artemisia annua germplasm resources in Yun-Gui plateau].
PubMed:
Preparation of molecularly imprinted polymers for artemisinin based on the surfaces of silica gel.
PubMed:
Stereolability of dihydroartemisinin, an antimalarial drug: a comprehensive thermodynamic investigation. Part 1.
PubMed:
A combination of ultrasonic-assisted extraction with RRLC-QQQ method for the determination of artemisinin in the Chinese herb Artemisia annua L.
PubMed:
Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo.
PubMed:
Pseudonocardia bannaensis sp. nov., a novel actinomycete isolated from the surface-sterilized roots of Artemisia annua L.
PubMed:
[Correlation and path analysis on artemisinin content and yield with different agronomic traits of Artemisia annua].
PubMed:
[Effects of three Chinese herbal antidotes (Herba artemisiae annuae, Herba hedyotis diffusae and Rhizoma cimicifugae) and their different combinations on regulated on activation normal T cell expressed and secreated expression in MRL/lpr mice].
PubMed:
Toxic metal contamination in Artemisia annua L. herbal preparations from different commercial sources in China.
PubMed:
Anti-malarial activity of Holarrhena antidysenterica and Viola canescens, plants traditionally used against malaria in the Garhwal region of north-west Himalaya.
PubMed:
Nocardia artemisiae sp. nov., an endophytic actinobacterium isolated from a surface-sterilized stem of Artemisia annua L.
PubMed:
Phytomonospora endophytica gen. nov., sp. nov., isolated from the roots of Artemisia annua L.
PubMed:
Chemotype-dependent metabolic response to methyl jasmonate elicitation in Artemisia annua.
PubMed:
Improved traditional phytomedicines in current use for the clinical treatment of malaria.
PubMed:
Dinitroaliphatics as linkers: application in the synthesis of novel artemisinin carba-dimer.
PubMed:
Screening the Hemostatic Active Fraction of Artemisia annua L. In-vitro.
PubMed:
The presence of amorpha-4, 11-diene synthase, a key enzyme in artemisinin production in ten Artemisia species.
PubMed:
The production of the sesquiterpene β-caryophyllene in a transgenic strain of the cyanobacterium Synechocystis.
PubMed:
Metabolic engineering of artemisinin biosynthesis in Artemisia annua L.
PubMed:
[Breeding and spreading of new vairety "Yu-Qing No. 1" of Artemisia annua].
PubMed:
The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes.
PubMed:
Conventional and long-circulating liposomes of artemisinin: preparation, characterization, and pharmacokinetic profile in mice.
PubMed:
Methyl jasmonate and miconazole differently affect arteminisin production and gene expression in Artemisia annua suspension cultures.
PubMed:
Quantification of the total amount of artemisinin in leaf samples by thin layer chromatography.
PubMed:
A new sesquiterpene and other constituents from Saussurea lappa root.
PubMed:
Tetraoxanes: synthetic and medicinal chemistry perspective.
PubMed:
Survey of artemisinin production by diverse Artemisia species in northern Pakistan.
PubMed:
Simultaneous analysis of three bioactive compounds in Artemisia annua hairy root cultures by reversed-phase high-performance liquid chromatography-diode array detector.
PubMed:
Artemisinin inhibits extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 expression via a protein kinase Cδ/p38/extracellular signal-regulated kinase pathway in phorbol myristate acetate-induced THP-1 macrophages.
PubMed:
The biosynthesis of artemisinin (Qinghaosu) and the phytochemistry of Artemisia annua L. (Qinghao).
PubMed:
Isolation, characterization and structural studies of amorpha - 4, 11-diene synthase (ADS(3963)) from Artemisia annua L.
PubMed:
Pseudonocardia kunmingensis sp. nov., an actinobacterium isolated from surface-sterilized roots of Artemisia annua L.
PubMed:
Methyl jasmonate counteracts boron toxicity by preventing oxidative stress and regulating antioxidant enzyme activities and artemisinin biosynthesis in Artemisia annua L.
PubMed:
Effects of artemisinin and Artemisia extracts on Haemonchus contortus in gerbils (Meriones unguiculatus).
PubMed:
Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants.
PubMed:
[Biotransformation of artemisinic acid by cell suspension cultures of Cephalotaxus fortunei and Artemisia annua].
PubMed:
[Accumulation and translocation of cadmium in soil and plant and its effects on growth of Artemisia annua and artemisinin content].
PubMed:
[Correlation and path analysis of artemisininum content and related factor on Artemisiae annie in Three Gorges reservoir area].
PubMed:
[Genetic and breeding of Artemisia annua L. for a sustainable production of the antimalarial drug artemisinin].
PubMed:
Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth.
PubMed:
Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells.
PubMed:
Antiplasmodial, anti-trypanosomal, anti-leishmanial and cytotoxicity activity of selected Tanzanian medicinal plants.
PubMed:
Reproductive development modulates gene expression and metabolite levels with possible feedback inhibition of artemisinin in Artemisia annua.
PubMed:
The production of artemisinin precursors in tobacco.
PubMed:
Biomass production of hairy roots of Artemisia annua and Arachis hypogaea in a scaled-up mist bioreactor.
PubMed:
Demand for malaria drug soars.
PubMed:
The genus Artemisia: a comprehensive review.
PubMed:
Chemical composition and antioxidant and anti-Listeria activities of essential oils obtained from some Egyptian plants.
PubMed:
Flavonoids from Artemisia annua L. as antioxidants and their potential synergism with artemisinin against malaria and cancer.
PubMed:
Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties.
PubMed:
A glandular trichome-specific monoterpene alcohol dehydrogenase from Artemisia annua.
PubMed:
Artemisinin-based combination therapies and their introduction in Japan.
PubMed:
Anticancer activity of botanical compounds in ancient fermented beverages (review).
PubMed:
Pseudonocardia artemisiae sp. nov., isolated from surface-sterilized Artemisia annua L.
PubMed:
Computational analysis of the evolution of 1-deoxy-D-xylulose-5-phosphate Reductoisomerase, an important enzyme in plant terpene biosynthesis.
PubMed:
Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum.
PubMed:
The molecular cloning of dihydroartemisinic aldehyde reductase and its implication in artemisinin biosynthesis in Artemisia annua.
PubMed:
Molecular cloning and characterization of a broad substrate terpenoid oxidoreductase from Artemisia annua.
PubMed:
In vitro antiplasmodial and phytochemical study of five Artemisia species from Iran and in vivo activity of two species.
PubMed:
Mapping the potential distribution of high artemisinin-yielding Artemisia annua L. (Qinghao) in China with a geographic information system.
PubMed:
Nonomuraea endophytica sp. nov., an endophytic actinomycete isolated from Artemisia annua L.
PubMed:
Effect of sugars on artemisinin production in Artemisia annua L.: transcription and metabolite measurements.
PubMed:
[Effects of zinc manganese and boron on artemisinin and yields of Artemisia annua].
PubMed:
Effect of artemisinin on oocyst wall formation and sporulation during Eimeria tenella infection.
PubMed:
Ardeemins and cytochalasins from Aspergillus terreus residing in Artemisia annua.
PubMed:
Inhibition of tumor cell proliferation and induction of apoptosis in human lung carcinoma 95-D cells by a new sesquiterpene from hairy root cultures of Artemisia annua.
PubMed:
Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity.
PubMed:
Effect of miconazole and terbinafine on artemisinin content of shooty teratoma of Artemisia annua.
PubMed:
Comparative quantitative analysis of artemisinin by chromatography and qNMR.
PubMed:
Enhancement of artemisinin content through four cycles of recurrent selection with relation to heritability, correlation and molecular marker in Artemisia annua L.
PubMed:
[Establishment of canditate core collection of Artemisia annua from China].
PubMed:
[Studies on flavonoids and their antioxidant activities of Artemisia annua].
PubMed:
A new cytotoxic trichothecene macrolide from the endophyte Myrothecium roridum.
PubMed:
Antibacterial activity of some Artemisia species extract.
PubMed:
Effects of ethanol extract of Artemisia annua L. against monogenean parasites of Heterobranchus longifilis.
PubMed:
Merging traditional Chinese medicine with modern drug discovery technologies to find novel drugs and functional foods.
PubMed:
Larvicidal activity of Artemisia annua L. callus culture against Anopheles stephensi larvae.
PubMed:
DMSO triggers the generation of ROS leading to an increase in artemisinin and dihydroartemisinic acid in Artemisia annua shoot cultures.
PubMed:
Metabolomic investigation of the ethnopharmacological use of Artemisia afra with NMR spectroscopy and multivariate data analysis.
PubMed:
The genetic map of Artemisia annua L. identifies loci affecting yield of the antimalarial drug artemisinin.
PubMed:
Plant science. The botanical solution for malaria.
PubMed:
Drying affects artemisinin, dihydroartemisinic acid, artemisinic acid, and the antioxidant capacity of Artemisia annua L. leaves.
PubMed:
Structural and functional characterization of HMG-COA reductase from Artemisia annua.
PubMed:
[Correlation analysis on main agronomic characters, yield per plant, artemisinin percentage contents and total artemisinin content per plant of Artemisia annua].
PubMed:
[Effects of application of N, P and K and plant density on growth of Artemisia annua and yield of artemisinin].
PubMed:
[Optimal measure for cultivation of Artemisia annua with high seeds yield].
PubMed:
[Recent advances in the study of amorpha-4,11-diene synthase and its metabolic engineering].
PubMed:
Senescent leaves of Artemisia annua are one of the most active organs for overexpression of artemisinin biosynthesis responsible genes upon burst of singlet oxygen.
PubMed:
Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study.
PubMed:
A protocol for HPLC-based activity profiling for natural products with activities against tropical parasites.
PubMed:
Anticancer activities of artemisinin and its bioactive derivatives.
PubMed:
Isolation and characterization of AaWRKY1, an Artemisia annua transcription factor that regulates the amorpha-4,11-diene synthase gene, a key gene of artemisinin biosynthesis.
PubMed:
[Analysis of essential oil in herbal pair Artemisia annua-Agastache rugosa by GC-MS and chemometric resolution method].
PubMed:
Immunosuppressive effect of ethanol extract of Artemisia annua on specific antibody and cellular responses of mice against ovalbumin.
PubMed:
Artemisinin-transferrin conjugate retards growth of breast tumors in the rat.
PubMed:
Coartem: the journey to the clinic.
PubMed:
Insecticidal activity of essential oils from native medicinal plants of Central Argentina against the house fly, Musca domestica (L.).
PubMed:
Global characterization of Artemisia annua glandular trichome transcriptome using 454 pyrosequencing.
PubMed:
Discovery, mechanisms of action and combination therapy of artemisinin.
PubMed:
Simple field assays to check quality of current artemisinin-based antimalarial combination formulations.
PubMed:
Antimalarials and the fight against malaria in Brazil.
PubMed:
Azithromycin inhibits vertical transmission of Toxoplasma gondii in Calomys callosus (Rodentia: Cricetidae).
PubMed:
Localization of enzymes of artemisinin biosynthesis to the apical cells of glandular secretory trichomes of Artemisia annua L.
PubMed:
Streptomyces artemisiae sp. nov., isolated from surface-sterilized tissue of Artemisia annua L.
PubMed:
Stimulation of artemisinin synthesis by combined cerebroside and nitric oxide elicitation in Artemisia annua hairy roots.
PubMed:
Overexpression of the HMG-CoA reductase gene leads to enhanced artemisinin biosynthesis in transgenic Artemisia annua plants.
PubMed:
Isolation and identification of novel genes involved in artemisinin production from flowers of Artemisia annua using suppression subtractive hybridization and metabolite analysis.
PubMed:
Secondary metabolic profiling and artemisinin biosynthesis of two genotypes of Artemisia annua.
PubMed:
Salicylic acid activates artemisinin biosynthesis in Artemisia annua L.
PubMed:
Effects of Artemisia annua L. (Asteracea) on the digestive enzymatic profiles and the cellular immune reactions of the Sunn pest, Eurygaster integriceps (Heteroptera: Scutellaridae), against Beauveria bassiana.
PubMed:
Enhancement of artemisinin concentration and yield in response to optimization of nitrogen and potassium supply to Artemisia annua.
PubMed:
[Effect of different soil water treatments on physiological characteristics and yield of Artemisia annua].
PubMed:
[Inspection on result of artemisinin content rank distribution in Guangxi].
PubMed:
Simple and rapid micro-scale quantification of artemisinin in living Artemisia annua L. by improved gas chromatography with electron-capture detection.
PubMed:
Synthesis and DNA polymerase alpha and beta inhibitory activity of alkyl p-coumarates and related compounds.
PubMed:
Three new triterpenoid saponins from the leaves and stems of Panax quinquefolium.
PubMed:
Degradation and ecotoxicity of the biomedical drug artemisinin in soil.
PubMed:
Toxoplasma gondii: effects of Artemisia annua L. on susceptibility to infection in experimental models in vitro and in vivo.
PubMed:
Evaluation of Artemisia annua infusion efficacy for the treatment of malaria in Plasmodium chabaudi chabaudi infected mice.
PubMed:
Cellulase production by six Trichoderma spp. fermented on medicinal plant processings.
PubMed:
Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells.
PubMed:
Development of HPLC analytical protocols for quantification of artemisinin in biomass and extracts.
PubMed:
Modulation of the antifungal activity of new medicinal plant extracts active on Candida glabrata by the major transporters and regulators of the pleiotropic drug-resistance network in Saccharomyces cerevisiae.
PubMed:
Drug resistance in Plasmodium: natural products in the fight against malaria.
PubMed:
Novel artemisinin and curcumin micellar formulations: drug solubility studies by NMR spectroscopy.
PubMed:
The improvement of amorpha-4,11-diene production by a yeast-conform variant.
PubMed:
Development of a sensitive monoclonal antibody-based enzyme-linked immunosorbent assay for the antimalaria active ingredient artemisinin in the Chinese herb Artemisia annua L.
PubMed:
Global health. Malaria drugs, the Coca-Cola way.
PubMed:
Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression.
PubMed:
Effects of low-dose gamma irradiation on artemisinin content and amorpha-4,11-diene synthase activity in Artemisia annua L.
PubMed:
[Study on climate regionalization of Artemisia annuua in Guangxi].
PubMed:
Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis.
PubMed:
Recent advances in artemisinin production through heterologous expression.
PubMed:
Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid.
PubMed:
Analysis of underivatized artemisinin and related sesquiterpene lactones by high-performance liquid chromatography with ultraviolet detection.
PubMed:
Making artemisinin.
PubMed:
Artemisia annua as a self-reliant treatment for malaria in developing countries.
PubMed:
Synthesis and anti-cancer activity of covalent conjugates of artemisinin and a transferrin-receptor targeting peptide.
PubMed:
Quantitative transcript profiling reveals down-regulation of A sterol pathway relevant gene and overexpression of artemisinin biogenetic genes in transgenic Artemisia annua plants.
PubMed:
Effect of drying temperature on essential oil content and composition of sweet wormwood (Artemisia annua) growing wild in Iran.
PubMed:
Larvicidal and adulticidal activities of some medicinal plants against the malarial vector, Anopheles stephensi (Liston).
PubMed:
Artemisinins: their growing importance in medicine.
PubMed:
The antiviral activities of artemisinin and artesunate.
PubMed:
Nitric oxide potentiates oligosaccharide-induced artemisinin production in Artemisia annua hairy roots.
PubMed:
Expression of a synthetic Artemesia annua amorphadiene synthase in Aspergillus nidulans yields altered product distribution.
PubMed:
Development of transgenic Artemisia annua (Chinese wormwood) plants with an enhanced content of artemisinin, an effective anti-malarial drug, by hairpin-RNA-mediated gene silencing.
PubMed:
[Evaluation on germplasm resources of main production area of Artemisia annua in China].
PubMed:
Artesunate derived from traditional Chinese medicine induces DNA damage and repair.
PubMed:
The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua.
PubMed:
Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells.
PubMed:
Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial.
PubMed:
Artemisinin--an innovative cornerstone for anti-malaria therapy.
PubMed:
Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry.
PubMed:
Artemisinin production by shoot regeneration of Artemisia annua L. using thidiazuron.
PubMed:
The rapid determination of artemisinin by post-column derivatization high-performance liquid chromatography using matrix solid-phase dispersion method.
PubMed:
Affordable and sensitive determination of artemisinin in Artemisia annua L. by gas chromatography with electron-capture detection.
PubMed:
[Increase of copy number of HMG-CoA reductase and FPP synthase genes improves the amorpha4,11-diene production in engineered yeast].
PubMed:
Engineering triterpene production in Saccharomyces cerevisiae-beta-amyrin synthase from Artemisia annua.
PubMed:
[Investigation and controlling measure of main diseases and pests on Artemisia annua].
PubMed:
A rapid method for the quantification of artemisinin in Artemisia annua L. plants cultivated for the first time in Burundi.
PubMed:
[Cloning and bioinformatics analysis of P450 cDNA in Artemisia annua].
PubMed:
[Determination of artemisinin in Artemisia annua by the ultraviolet spectrophotometric].
PubMed:
[Advances in sesquiterpene synthases cyclases of Artemisia annua].
PubMed:
Cloning of artemisinin biosynthetic cDNAs and novel ESTs and quantification of low temperature-induced gene overexpression.
PubMed:
Effect of arbuscular mycorrhizal (AM) colonization on terpene emission and content of Artemisia annua L.
PubMed:
Tissue specificity and developmental pattern of amorpha-4,11-diene synthase (ADS) proved by ADS promoter-driven GUS expression in the heterologous plant, Arabidopsis thaliana.
PubMed:
Quantification of artemisinin in Artemisia annua extracts by 1H-NMR.
PubMed:
Toxicity of artemisinin [Artemisia annua L.] in two different periods of pregnancy in Wistar rats.
PubMed:
Development and validation of a simple thin layer chromatographic method for the analysis of artemisinin in Artemisia annua L. plant extracts.
PubMed:
[Determination of artemisinin, arteannuin B and artemisinic acid in Herba Artemisiae Annuae by HPLC-UV-ELSD].
PubMed:
Production of artemisinin by genetically-modified microbes.
PubMed:
Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry.
PubMed:
Ensuring sustained ACT production and reliable artemisinin supply.
PubMed:
Treatment of Haemoproteus tinnunculi in falcons.
PubMed:
Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua.
PubMed:
Artemisinin triggers induction of cell-cycle arrest and apoptosis in Leishmania donovani promastigotes.
PubMed:
Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways.
PubMed:
Artemisinin and sesquiterpene precursors in dead and green leaves of Artemisia annua L. crops.
PubMed:
Ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in British Columbia, Canada.
PubMed:
Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells.
PubMed:
Preparation of a novel monoclonal antibody against the antimalarial drugs, artemisinin and artesunate.
PubMed:
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
PubMed:
Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells.
PubMed:
Effects of arbuscular mycorrhiza and phosphorus application on artemisinin concentration in Artemisia annua L.
PubMed:
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2.
PubMed:
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1.
PubMed:
TLC-densitometric analysis of artemisinin for the rapid screening of high-producing plantlets of Artemisia annua L.
PubMed:
Improvement of artemisinin production by chitosan in hairy root cultures of Artemisia annua L.
PubMed:
Functional genomics and the biosynthesis of artemisinin.
PubMed:
An effective method for fast determination of artemisinin in Artemisia annua L. by high performance liquid chromatography with evaporative light scattering detection.
PubMed:
Isolation of high-purity casticin from Artemisia annua L. by high-speed counter-current chromatography.
PubMed:
Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside.
PubMed:
Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells.
PubMed:
Nutrient deficiency in the production of artemisinin, dihydroartemisinic acid, and artemisinic acid in Artemisia annua L.
PubMed:
[Extraction of artemisinin and synthesis of its derivates artesunate and artemether].
PubMed:
[Control of malaria: market for artemisinin and its derivatives].
PubMed:
Production of Artemisinin and Related Sesquiterpenes in Japanese Artemisia annua During a Vegetation Period.
PubMed:
Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon truncatum IFB-18, an endophyte of Artemisia annua.
PubMed:
Agrobacterium rhizogenes-mediated transformation of Artemisia annua: production of transgenic plants.
PubMed:
Sugars proportionately affect artemisinin production.
PubMed:
A TLC bioautographic assay for the detection of nitrofurantoin resistance reversal compound.
PubMed:
Comparative assessment of technologies for extraction of artemisinin.
PubMed:
Earlier flowering induced by over-expression of CO gene does not accompany increase of artemisinin biosynthesis in Artemisia annua.
PubMed:
Identification and characterization of major flavonoids and caffeoylquinic acids in three Compositae plants by LC/DAD-APCI/MS.
PubMed:
Analysis of Artemisia annua L. volatile oil by comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry.
PubMed:
[Studies on the chemical constituents of essential oil of Hunan Artemisia annua].
PubMed:
[The preparation of an elicitor from a fungal endophyte to enhance artemisinin production in hairy root cultures of Artemisia annua L].
PubMed:
Direct analysis of artemisinin from Artemisia annua L. using high-performance liquid chromatography with evaporative light scattering detector, and gas chromatography with flame ionization detector.
PubMed:
Improved conditions for production of recombinant plant sesquiterpene synthases in Escherichia coli.
PubMed:
Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV).
PubMed:
Using an aerosol deposition model to increase hairy root growth in a mist reactor.
PubMed:
Is the yin-yang nature of Chinese herbal medicine equivalent to antioxidation-oxidation?
PubMed:
Effective method for extraction of larvicidal component from leaves of Azadirachta indica and Artemisia annua Linn.
PubMed:
[Determination of artemisinin in Artemisia annuna by HPLC-ELSD].
PubMed:
Dihydroarteannuin ameliorates lupus symptom of BXSB mice by inhibiting production of TNF-alpha and blocking the signaling pathway NF-kappa B translocation.
PubMed:
Artemisinin: current state and perspectives for biotechnological production of an antimalarial drug.
PubMed:
From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements.
PubMed:
Artemisinin in traditional tea preparations of Artemisia annua.
PubMed:
Absolute configuration of new cytotoxic and other bioactive trichothecene macrolides.
PubMed:
Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography-electrospray quadrupole time-of-flight tandem mass spectrometry.
PubMed:
Production of the artemisinin precursor amorpha-4,11-diene by engineered Saccharomyces cerevisiae.
PubMed:
Production of the antimalarial drug precursor artemisinic acid in engineered yeast.
PubMed:
Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells.
PubMed:
Isoprenoid biosynthesis in Artemisia annua: cloning and heterologous expression of a germacrene A synthase from a glandular trichome cDNA library.
PubMed:
The history of qing hao in the Chinese materia medica.
PubMed:
Trichome dynamics and artemisinin accumulation during development and senescence of Artemisia annua leaves.
PubMed:
Medicinal plants and Malaria: an historical case study of research at the London School of Hygiene and Tropical Medicine in the twentieth century.
PubMed:
Simultaneous analysis of artemisinin and flavonoids of several extracts of Artemisia annua L. obtained from a commercial sample and a selected cultivar.
PubMed:
Targeting angiogenesis with integrative cancer therapies.
PubMed:
Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin.
PubMed:
Medicinal plants useful for malaria therapy in Okeigbo, Ondo State, Southwest Nigeria.
PubMed:
Artemisia annua as a herbal tea for malaria.
PubMed:
Oral artemisinin prevents and delays the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer in the rat.
PubMed:
Phytoextract-induced developmental deformities in malaria vector.
PubMed:
Simultaneous densitometric determination of artemisinin, artemisinic acid and arteannuin-B in Artemisia annua using reversed-phase thin layer chromatography.
PubMed:
Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells.
PubMed:
The herbal tea approach for artemisinin as a therapy for malaria?
PubMed:
Artesunate in the treatment of metastatic uveal melanoma--first experiences.
PubMed:
Laboratory evaluation of Artemisia annua L. extract and artemisinin activity against Epilachna paenulata and Spodoptera eridania.
PubMed:
Yeast model uncovers dual roles of mitochondria in action of artemisinin.
PubMed:
Amorpha-4,11-diene synthase: mechanism and stereochemistry of the enzymatic cyclization of farnesyl diphosphate.
PubMed:
Analysis of artemisinin in Artemisia annua L. by LC-MS with selected ion monitoring.
PubMed:
[Allelopathy of different plants on wheat, cucumber and radish seedlings].
PubMed:
[Advances in molecular regulation of artemisinin biosynthesis].
PubMed:
Expression, purification and characterization of recombinant (E)-beta-farnesene synthase from Artemisia annua.
PubMed:
Cloning and expression of a farnesyl diphosphate synthase in Centella asiatica (L.) Urban.
PubMed:
[Review of the use of artemisinin and its derivatives in the treatment of malaria].
PubMed:
Expression, purification, and characterization of recombinant amorpha-4,11-diene synthase from Artemisia annua L.
PubMed:
[Study on chromatogrqphic fingerprint of qingying injection].
PubMed:
The development of the antimalarial drugs with new type of chemical structure--qinghaosu and dihydroqinghaosu.
PubMed:
Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua.
PubMed:
Apoptosis of human umbilical vein endothelial cells induced by artesunate.
PubMed:
Progress in the research of artemisinin and its analogues as antimalarials: an update.
PubMed:
Alteration of biomass and artemisinin production in Artemisia annua hairy roots by media sterilization method and sugars.
PubMed:
Comment on: Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria.
PubMed:
Artemisinin induces apoptosis in human cancer cells.
PubMed:
Immunosuppressive activity of a molecule isolated from Artemisia annua on DTH responses compared with cyclosporin A.
PubMed:
Artesunate reduces chicken chorioallantoic membrane neovascularisation and exhibits antiangiogenic and apoptotic activity on human microvascular dermal endothelial cell.
PubMed:
[Induction of apoptosis of cultured hepatocarcinoma cell by essential oil of Artemisia Annul L].
PubMed:
Recent advances in artemisinin and its derivatives as antimalarial and antitumor agents.
PubMed:
Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria.
PubMed:
Studies on the effects of fpf1 gene on Artemisia annua flowering time and on the linkage between flowering and artemisinin biosynthesis.
PubMed:
Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1.
PubMed:
Prediction of anti-plasmodial activity of Artemisia annua extracts: application of 1H NMR spectroscopy and chemometrics.
PubMed:
Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood).
PubMed:
Postsynaptic dopamine (D(2))-mediated behavioural effects of high acute doses of artemisinin in rodents.
PubMed:
Repellency and toxicity of oil from Artemisia annua to certain stored-product beetles.
PubMed:
Central properties of the essential oil and the crude ethanol extract from aerial parts of Artemisia annua L.
PubMed:
Analysis of artemisinin by a packed-column supercritical fluid chromatography-atmospheric pressure chemical ionisation mass spectrometry technique.
PubMed:
Terpenoids from the seeds of Artemisia annua.
PubMed:
Artemisinins target the SERCA of Plasmodium falciparum.
PubMed:
Scale-up of Artemisia annua L. hairy root cultures produces complex patterns of terpenoid gene expression.
PubMed:
Optimization of cryopreservation of Artemisia annua L. callus.
PubMed:
Growth dynamics of Artemisia annua hairy roots in three culture systems.
PubMed:
Tetraploid Artemisia annua hairy roots produce more artemisinin than diploids.
PubMed:
[Experimental studies of antitumor effect of artesunate on liver cancer].
PubMed:
Artemisinin, a novel antimalarial drug: biochemical and molecular approaches for enhanced production.
PubMed:
Medicinal and aromatic plant materials as nitrification inhibitors for augmenting yield and nitrogen uptake of Japanese mint (Mentha arvensis L. Var. Piperascens).
PubMed:
[Analysis of essential oil from Artemisia annul L. by extraction of different methods].
PubMed:
Adhesion of plant roots to poly-L-lysine coated polypropylene substrates.
PubMed:
Plants against malaria, part 2: Artemisia annua (Qinghaosu or the sweet wormwood).
PubMed:
Two flavonols from Artemisa annua which potentiate the activity of berberine and norfloxacin against a resistant strain of Staphylococcus aureus.
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Activity against Plasmodium falciparum of cycloperoxide compounds obtained from the sponge Plakortis simplex.
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A cDNA clone for beta-caryophyllene synthase from Artemisia annua.
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Antibacterial and antioxidant activities of Artemisia annua essential oil.
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Growth of Artemisia annua hairy roots in liquid- and gas-phase reactors.
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[Experimental study on antiendotoxin effect of extracts from Artemisia annua L].
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Cloning and functional characterization of a beta-pinene synthase from Artemisia annua that shows a circadian pattern of expression.
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On-line conversion and determination of artemisinin using a flow-injection capillary electrophoresis system.
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[Artemisinine and artesunate in the treatment of malaria in Vietnam (1984-1999)].
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Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum.
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Molecular docking and 3-D-QSAR studies on the possible antimalarial mechanism of artemisinin analogues.
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Antiulcerogenic activity of some sesquiterpene lactones isolated from Artemisia annua.
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[Progress in studies on the artemisinin (qinghaosu)-type antimalarials].
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Simple and rapid physico-chemical methods to examine action of antimalarial drugs with hemin: its application to Artemisia annua constituents.
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Demonstrating the validity of natural products as anti-infective drugs.
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Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies.
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The genetics of artemisinin content in Artemisia annua L. and the breeding of high yielding cultivars.
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Antiparasitic properties of medicinal plants and other naturally occurring products.
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In vitro antiprotozoal effects of artemisinin on Neospora caninum.
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Antiulcerogenic activity of crude ethanol extract and some fractions obtained from aerial parts of Artemisia annua L.
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Deoxyarteannuin B, dihydro-deoxyarteannuin B and trans-5-hydroxy-2-isopropenyl-5-methylhex-3-en-1-ol from Artemisia anuua.
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Gas concentration effects on secondary metabolite production by plant cell cultures.
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Antioxidant activity and phenolic compounds in selected herbs.
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Artemisinin and its derivatives: an important new class of antimalarial agents.
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Toxicity, feeding deterrence, and effect of activity of 1,8-cineole from Artemisia annua on progeny production of Tribolium castanaeum (Coleoptera: Tenebrionidae).
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Effects of ipt gene expression on the physiological and chemical characteristics of Artemisia annua L.
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Antifungal activity of Artemisia annua endophyte cultures against phytopathogenic fungi.
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Amorpha-4,11-diene synthase: cloning and functional expression of a key enzyme in the biosynthetic pathway of the novel antimalarial drug artemisinin.
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Screening of the anticoccidial effects of herb extracts against Eimeria tenella.
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The anti-malarial artesunate is also active against cancer.
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Amorpha-4,11-diene synthase of Artemisia annua: cDNA isolation and bacterial expression of a terpene synthase involved in artemisinin biosynthesis.
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Purification and characterization of an enzyme involved in biochemical transformation of arteannuin B to artemisinin from Artemisia annua.
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The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects.
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Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L.
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Cloning and molecular analysis of two new sesquiterpene cyclases from Artemisia annua L.
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The growth of single roots of Artemisia annua in nutrient mist reactors.
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The regulation of solasodine production by Agrobacterium rhizogenes-transformed roots of Solanum aviculare.
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Expression of a chimeric farnesyl diphosphate synthase gene in Artemisia annua L. transgenic plants via Agrobacterium tumefaciens-mediated transformation.
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Preventive effect of artemether in experimental animals infected with Schistosoma mansoni.
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Seasonal variation of artemisinin and its biosynthetic precursors in plants of Artemisia annua of different geographical origin: proof for the existence of chemotypes.
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Current status of artemisinin and its derivatives as antimalarial drugs.
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Differential effects of orally versus parenterally administered qinghaosu derivative artemether in dogs.
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Seasonal variations of Artemisinin and its biosynthetic precursors in tetraploid Artemisia annua plants compared with the diploid wild-type.
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Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis.
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(3R)-Linalool synthase from Artemisia annua L.: cDNA isolation, characterization, and wound induction.
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Studies on dynamics of growth and biosynthesis of artemisinin in hairy roots of Artemisia annua L.
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Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L.
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The molecular cloning of 8-epicedrol synthase from Artemisia annua.
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Isolation and identification of dihydroartemisinic acid hydroperoxide from artemisia annua: A novel biosynthetic precursor of artemisinin
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Plants showing antiplasmodial activity--from crude extracts to isolated compounds.
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RAPD profile based genetic characterization of chemotypic variants of Artemisia annua L.
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Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication.
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Positioning, labelling and control of medical information: artesunate strategy and Arsumax development story.
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How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives?
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Isolation and identification of dihydroartemisinic acid from artemisia annua and its possible role in the biosynthesis of artemisinin
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[Artemisia annua for the treatment of malaria].
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Dietary modulation of avian coccidiosis.
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In vitro antiplasmodial activity of stem and root extracts of Nauclea latifolia S.M. (Rubiaceae).
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Bitter-sweet solutions for malaria: exploring natural remedies from the past.
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Extraction of artemisinin and artemisinic acid from Artemisia annua L. using supercritical carbon dioxide.
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Effect of plant density on the yields of artemisinin and essential oil in Artemisia annua cropped under low input cost management in North-Central India.
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Effects of components of Artemisia annua on coccidia infections in chickens.
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Antimalaric effect of an alcoholic extract of Artemisia ludoviciana mexicana in a rodent malaria model.
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Mist deposition onto hairy root cultures: aerosol modeling and experiments.
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A high-performance liquid chromatography analysis of plasma artemisinin using a glassy carbon electrode for reductive electrochemical detection.
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Artemisinin: an endoperoxidic antimalarial from Artemisia annua L.
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Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.
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State of the art of the production of the antimalarial compound artemisinin in plants.
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Agrobacterium tumefaciens-mediated transformation of Artemisia annua L. and regeneration of transgenic plants.
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Cloning and analysis of a cDNA encoding farnesyl diphosphate synthase from Artemisia annua.
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Isolation of a high artemisinic acid containing plant of Artemisia annua.
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Cryopreservation of transformed (hairy) roots of Artemisia annua.
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Immunoquantitative analysis of artemisinin from Artemisia annua using polyclonal antibodies.
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Relationship of artemisinin content of tissue-cultured, greenhouse-grown, and field-grown plants of Artemisia annua.
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Selection of high artemisinin yielding Artemisia annua.
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Developmental studies of Artemisia annua: flowering and artemisinin production under greenhouse and field conditions.
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Antimalarial activity in vitro of Cochlospermum tinctorium tubercle extracts.
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Hairy root culture of Artemisia annua L. by Ri plasmid transformation and biosynthesis of artemisinin.
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Progress in the research of artemisinin-related antimalarials: an update.
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Artemisinin, Related Sesquiterpenes, and Essential Oil in Artemisia annua During a Vegetation Period in Vietnam.
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Artemisinin: current status.
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Extraction of artemisinin and artemisinic acid: preparation of artemether and new analogues.
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Agricultural production of artemisinin--a review.
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Cytotoxic terpenoids and flavonoids from Artemisia annua.
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An Improved Method for the Isolation of Qinghao (Artemisinic) Acid from Artemisia annua.
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Bioconversion of arteannuin B to artemisinin.
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A rapid screening method for artemisinin and its congeners using ms/ms: search for new analogues in Artemisia annua.
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Crystal structure of artemisinic acid: a possible biogenetic precursor of antimalarial artemisinin from Artemisia annua.
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The chemotherapy of rodent malaria. XLVIII. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 1: Studies leading to the development of novel cis-fused cyclopenteno derivatives.
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[Antipyretic and anti-inflammatory effects of Artemisia annua L].
PubMed:
[Pharmacokinetics of dihydroqinghaosu in human volunteers and comparison with qinghaosu].
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Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures.
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Stereoselective synthesis and antimalarial activity of alpha-artelinic acid from artemisinin.
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Artemisinin G: A Sesquiterpene from Artemisia annua.
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[Studies on the antimalarial action of gelatin capsule of Artemisia annua].
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Trial of antimalarial potential of extracts of Artemisia annua grown in Myanmar.
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Can ethnopharmacology contribute to the development of antimalarial agents?
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Artemisia annua L.: a source of novel antimalarial drugs.
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[The pharmacokinetics of dihydroqinghasu given orally to rabbits and dogs].
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Effects of artemisinin, dihydroartemisinin and arteether on immune responses of normal mice.
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Cultivation of artemisia annua L plantlets in a bioreactor containing a single carbon and a single nitrogen source.
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Antiplasmodial activity of Artemisia annua plant cell cultures.
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Evalutation of Artemisia annua strains for higher artemisinin production.
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Isolation of Epi-Deoxyarteannuin B from Artemisia annua.
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An investigation on in vivo allergenicity of Artemisia annua leaves and stems.
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Isolation of Arteannuic Acid from Artemisia annua.
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Effect of Sterol Inhibitors on the Incorporation of 14C-Isopentenyl Pyrophosphate into Artemisinin by a Cell-Free System from Artemisia annua Tissue Cultures and Plants.
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Analysis of the antimalarial sesquiterpene artemisinin in Artemisia annua by high-performance liquid chromatography (HPLC) with postcolumn derivatization and ultraviolet detection.
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[Biochemical study of pollens of the genus Artemisia].
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[Pollen counts (from Ambrosia and Artemisia) in Lyon-Bron from 1982 to 1985].
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The effect of combinations of qinghaosu (artemisinin) with standard antimalarial drugs in the suppressive treatment of malaria in mice.
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Potentiation of the antimalarial activity of qinghaosu by methoxylated flavones.
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Formation of Artemisinin in Artemisia annua During One Vegetation Period*,1.
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The chemotherapy of rodent malaria, XL. The action of artemisinin and related sesquiterpenes.
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Production of artemisinin in tissue cultures of Artemisia annua.
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[Tissue culture of Artemisia annual. II. Some factors: effect on callus formed on Artemisia annua and green shoot regeneration].
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Reductive electrochemical HPLC assay for artemisinin (qinghaosu).
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Artemisitene, a New Sesquiterpene Lactone Endoperoxide from Artemisia annua.
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Plants as Sources of Antimalarial Drugs Part. 1. In vitro Test Method for the Evaluation of Crude Extracts from Plants.
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[The constituents of young Artemisia annua].
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Qinghaosu (artemisinin): an antimalarial drug from China.
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[Determination of qinghaosu (arteannuin) in Artemisia annua L. by pulse polarography].
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Metabolic fate of Qinghaosu in rats; a new TLC densitometric method for its determination in biological material.
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Isolation of artemisinin (qinghaosu) from Artemisia annua growing in the United States.
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Immunosuppressive action of Qinghaosu.
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[Several properties of beta-galactosidase from Artemisia annua L].
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[Chemical constituents of volatile oils of Artemisia annua].
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Studies on the constituents of Artemisia annua Part II.
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[Studies on the constituents of Artemisia annua L. (author's transl)].
PubMed:
[Studies on the constituents of Qing-hao (Artemisia annua L.) (author's transl)].
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Phytochemical investigation of the herba of Artemisia annua.
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[Studies on the essential oils of Artemisia annua L. V].