sanguinaria canadensis root tincture

bloodroot root tincture

CAS: 84929-48-6

Identification

Namesanguinaria canadensis root tincture
CAS Number84929-48-6
FDA UNIISearch

Regulatory

Physical Properties

Food Chemicals Codex Listed No

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for sanguinaria canadensis root tincture usage levels up tonot for fragrance use.
Recommendation for sanguinaria canadensis root tincture flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

sanguinaria canadensis root

Synonyms

blood root tincture bloodroot root tincture red- puccoon root tincture sanguinaria australis root tincture sanguinaria canadensis var. rotundifolia root tincture sanguinaria dilleniana root tincture sanguinaria root tincture PubMed: Rapid human melanoma cell death induced by sanguinarine through oxidative stress. PubMed: Consequences of intratumoral injection of a herbal preparation containing blood root (Sanguinaria canadensis) extract in two dogs. PubMed: The mechanism of action of sanguinarine against methicillin-resistant Staphylococcus aureus. PubMed: An Internet misadventure: bloodroot salve toxicity. PubMed: Bloodroot (Sanguinaria canadensis L., Papaveraceae) Enhances Proliferation and Cytokine Production by Human Peripheral Blood Mononuclear Cells in an In Vitro Model. PubMed: Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3. PubMed: In vitro screening for the tumoricidal properties of international medicinal herbs. PubMed: Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation. PubMed: Sanguinarine-induced apoptosis: generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL. PubMed: Effects of aqueous extracts from five species of the family Papaveraceae on selected aquatic organisms. PubMed: Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. PubMed: Sanguinarine inhibits VEGF-induced angiogenesis in a fibrin gel matrix. PubMed: Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization. PubMed: Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production. PubMed: Suppression of angiogenesis by the plant alkaloid, sanguinarine. PubMed: Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes.