quinine sulfate dihydrate

quinine, sulfate (2:1), dihydrate

CAS: 6119-70-6 C20 H24 N2 O2.1/2H2 O4 S.2H2 O

Identification

Namequinine sulfate dihydrate
IUPAC(R)-[(5R,7S)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid; dihydrate
CAS Number6119-70-6
FDA UNIIKF7Z0E0Q2B
Molecular FormulaC20 H24 N2 O2.1/2H2 O4 S.2H2 O
MDL NumberMFCD00150792
Beilstein6113937

Regulatory

JECFA Food AdditiveQuinine Sulfate
FEMA Number2977
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)6119-70-6 ; QUININE SULFATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance dull white crystalline powder (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 224.00 to 225.00 °C. @ 760.00 mm Hg
Boiling Point 495.90 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000000 mmHg @ 25.00 °C. (est)
Flash Point 489.00 °F. TCC ( 253.70 °C. ) (est)
logP (o/w) 3.440 (est)
Shelf Life 12.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in ether

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents and adjuvants
Recommendation for quinine sulfate dihydrate usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

antimalarial

Natural Occurrence

not found in nature

Synonyms

cinchonan-9-ol, 6'-methoxy-, (3a,8a,9R)-, sulfate, hydrate (2:1:2) (salt) cinchonan-9-ol, 6'-methoxy-, (8a,9R)-, sulfate (2:1) (salt), dihydrate (R)-[(5R,7S)-5- ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid; dihydrate (8alpha,9R)-6'- methoxycinchonan-9-ol sulfate dihydrate (2:1) salt 6'- methoxycinchonan-9-ol sulfate dihydrate, (8a,9R)-, (2:1) (salt) (3a,8a,9R)-6'- methoxycinchonan-9-ol sulfate hydrate (2:1:2) quinine hemisulfate monohydrate quinine sulfate (2:1) (salt) dihydrate quinine sulfate dihydrate USP quinine, sulfate (2:1), dihydrate Try the PubMed Search.